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Use of Electromagnetic Navigational Transthoracic Needle Aspiration (E-TTNA) for Sampling of Lung Nodules

Lung nodule evaluation represents a clinical challenge especially in patients with intermediate risk for malignancy. Multiple technologies are presently ...

Johns Hopkins University

Experiments and mathematical modeling show that complex flows driven by unexpected flagellar arrangements are induced when peritrichously flagellated bacteria are confined in a thin layer of fluid, between asymmetric boundaries. The flagella apparently form a dynamic bipolar assembly rather than the single bundle characteristic of free swimming bacteria, and the resulting flow is observed to circulate around the cell body. It ranges over several cell diameters, in contrast to the small extent of the flows surrounding free swimmers. Results also suggest that flagellar bundles on bacteria that lie flat on a solid substrate have an effective rotation rate slower than "free" flagella. This discovery extends our knowledge of the dynamic geometry of bacteria and their flagella, and reveals new mechanisms for motility-associated molecular transport and intercellular communication.

Unexpected bipolar flagellar arrangements and long-range flows driven by bacteria near solid boundaries.

To evaluate the efficacy and safety of iron(III) polymaltose complex (Maltofer(®)) versus ferrous sulfate in iron-deficient pregnant women using recommended doses.

Efficacy and safety of oral iron(III) polymaltose complex versus ferrous sulfate in pregnant women with iron-deficiency anemia: a multicenter, randomized, controlled study.

The diagnosis of the peripheral lung lesion has been a long-standing clinical challenge--balancing accuracy with patient safety. With recent data revealing mortality benefits with lung cancer screening via low-dose computed tomography, now more than ever, clinicians will be challenged with the task of providing the means to provide a safe and minimally invasive method of obtaining accurate tissue diagnostics for the pulmonary nodule. In this review, we present available technologies to aid clinicians in attempts at minimally invasive techniques and the data supporting their use. In addition, we review novel tools under investigation that may further increase yield and provide additional benefit in obtaining an early diagnosis of lung cancer.

Novel bronchoscopic strategies for the diagnosis of peripheral lung lesions: present techniques and future directions.

Pneumomediastinum and pneumopericardium after endobronchial ultrasound-guided transbronchial needle aspiration.

The objective of this study was to compare the accuracy of a handheld digital manometer (DM) and U-tube (UT) manometer with an electronic transducer (ET) manometer during thoracentesis.

Comparison of pleural pressure measuring instruments.

Malignant pleural effusion remains a common complication of advanced malignancies. Indwelling tunneled pleural catheter placement provides effective palliation, but can be associated with complications, including infection. Hematologic malignancy in particular and the associated immunosuppressive treatment regimens may increase infectious complications. This study aimed to review the outcomes of hematological malignancy patients undergoing indwelling tunneled pleural catheter placement.

The Use of Indwelling Tunneled Pleural Catheters for Recurrent Pleural Effusions in Patients with Hematologic Malignancies: A Multicenter Study.

The indwelling tunneled pleural catheter has altered the management of patients with dyspnea related to malignant pleural effusions. Indwelling tunneled pleural catheter placement does not remain free from risk; with infection the most commonly reported risk.

Article	Year
Unexpected bipolar flagellar arrangements and long-range flows driven by bacteria near solid boundaries. Physical review letters\| PubMed ID: 18999716	2008
Efficacy and safety of oral iron(III) polymaltose complex versus ferrous sulfate in pregnant women with iron-deficiency anemia: a multicenter, randomized, controlled study. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians\| PubMed ID: 21859366	2011
Novel bronchoscopic strategies for the diagnosis of peripheral lung lesions: present techniques and future directions. Respirology (Carlton, Vic.)\| PubMed ID: 24797257	2014
Pneumomediastinum and pneumopericardium after endobronchial ultrasound-guided transbronchial needle aspiration. Annals of the American Thoracic Society\| PubMed ID: 24828808	2014
Comparison of pleural pressure measuring instruments. Chest\| PubMed ID: 24853674	2014
The Use of Indwelling Tunneled Pleural Catheters for Recurrent Pleural Effusions in Patients with Hematologic Malignancies: A Multicenter Study. Chest\| PubMed ID: 25789576	2015
A Quality Improvement Intervention to Reduce Indwelling Tunneled Pleural Catheter Infection Rates. Annals of the American Thoracic Society\| PubMed ID: 25871702	2015

Ricardo Ortiz

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