Aron M. Geurts

Departments of Physiology, Medical College of Wisconsin

Affiliated withMedical College of Wisconsin

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 5	2015
Publication title	2017

Other Publications

Article	Year
Structure-function analysis of the inverted terminal repeats of the sleeping beauty transposon. Journal of molecular biology\| PubMed ID: 12083513	2002
Gene transfer into genomes of human cells by the sleeping beauty transposon system. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 12842434	2003
Transposon vectors for gene-trap insertional mutagenesis in vertebrates. Genesis (New York, N.Y. : 2000)\| PubMed ID: 15286994	2004
Target-site preferences of Sleeping Beauty transposons. Journal of molecular biology\| PubMed ID: 15663935	2005
Structure-based prediction of insertion-site preferences of transposons into chromosomes. Nucleic acids research\| PubMed ID: 16717285	2006
Conditional gene expression in the mouse using a Sleeping Beauty gene-trap transposon. BMC biotechnology\| PubMed ID: 16800892	2006
Gene mutations and genomic rearrangements in the mouse as a result of transposon mobilization from chromosomal concatemers. PLoS genetics\| PubMed ID: 17009875	2006
Efficient transgenic rat production by a lentiviral vector. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 17322424	2007
Generation of rat mutants using a coat color-tagged Sleeping Beauty transposon system. Mammalian genome : official journal of the International Mammalian Genome Society\| PubMed ID: 17557177	2007
Predicting preferential DNA vector insertion sites: implications for functional genomics and gene therapy. Genome biology\| PubMed ID: 18047689	2007
Progress and prospects in rat genetics: a community view. Nature genetics\| PubMed ID: 18443588	2008
Knockout rats via embryo microinjection of zinc-finger nucleases. Science (New York, N.Y.)\| PubMed ID: 19628861	2009
Generation of gene-specific mutated rats using zinc-finger nucleases. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 20013236	2010
Efficient mammalian germline transgenesis by cis-enhanced Sleeping Beauty transposition. Transgenic research\| PubMed ID: 20352328	2011
Zinc-finger nucleases: new strategies to target the rat genome. Clinical science (London, England : 1979)\| PubMed ID: 20615201	2010
Gene targeting in the rat: advances and opportunities. Trends in genetics : TIG\| PubMed ID: 20869786	2010
Creation and characterization of a renin knockout rat. Hypertension\| PubMed ID: 21242461	2011
Exacerbated pulmonary arterial hypertension and right ventricular hypertrophy in animals with loss of function of extracellular superoxide dismutase. Hypertension\| PubMed ID: 21730301	2011
The emerging role for rat models in gene discovery. Mammalian genome : official journal of the International Mammalian Genome Society\| PubMed ID: 21732192	2011
Efficient non-viral integration and stable gene expression in multipotent adult progenitor cells. Stem cells international\| PubMed ID: 21977042	2011
Increased expression of NAD(P)H oxidase subunit p67(phox) in the renal medulla contributes to excess oxidative stress and salt-sensitive hypertension. Cell metabolism\| PubMed ID: 22326221	2012
Transposon-mediated transgenesis, transgenic rescue, and tissue-specific gene expression in rodents and rabbits. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 23195032	2013
Heterozygous knockout of transforming growth factor-β1 protects Dahl S rats against high salt-induced renal injury. Physiological genomics\| PubMed ID: 23249995	2013
Genetic mutation of recombination activating gene 1 in Dahl salt-sensitive rats attenuates hypertension and renal damage. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 23364523	2013
Derivation and genetic modification of embryonic stem cells from disease-model inbred rat strains. Stem cells and development\| PubMed ID: 23635087	2013
Rats are the smart choice: Rationale for a renewed focus on rats in behavioral genetics. Neuropharmacology\| PubMed ID: 23791960	2014
Gene targeting in NOD mouse embryos using zinc-finger nucleases. Diabetes\| PubMed ID: 23974926	2014
Identifying multiple causative genes at a single GWAS locus. Genome research\| PubMed ID: 24006081	2013
Amelioration of salt-induced vascular dysfunction in mesenteric arteries of Dahl salt-sensitive rats by missense mutation of extracellular superoxide dismutase. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 24322611	2014
CD247 modulates blood pressure by altering T-lymphocyte infiltration in the kidney. Hypertension\| PubMed ID: 24343121	2014
HV1 acts as a sodium sensor and promotes superoxide production in medullary thick ascending limb of Dahl salt-sensitive rats. Hypertension\| PubMed ID: 24935944	2014
Mutation of Plekha7 attenuates salt-sensitive hypertension in the rat. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 25136115	2014
CXM: a new tool for mapping breast cancer risk in the tumor microenvironment. Cancer research\| PubMed ID: 25172839	2014
Zinc-finger nuclease knockout of dual-specificity protein phosphatase-5 enhances the myogenic response and autoregulation of cerebral blood flow in FHH.1BN rats. PloS one\| PubMed ID: 25397684	2014
Maternal diet during gestation and lactation modifies the severity of salt-induced hypertension and renal injury in dahl salt-sensitive rats. Hypertension\| PubMed ID: 25452472	2015
Impaired myogenic response and autoregulation of cerebral blood flow is rescued in CYP4A1 transgenic Dahl salt-sensitive rat. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 25540098	2015
SH2B3 Is a Genetic Determinant of Cardiac Inflammation and Fibrosis. Circulation. Cardiovascular genetics\| PubMed ID: 25628389	2015
Mutation of SH2B3 (LNK), a genome-wide association study candidate for hypertension, attenuates Dahl salt-sensitive hypertension via inflammatory modulation. Hypertension\| PubMed ID: 25776069	2015
Efficient CRISPR/Cas9-Mediated Genome Editing in Mice by Zygote Electroporation of Nuclease. Genetics\| PubMed ID: 25819794	2015