Twan Lammers

Experimental Molecular Imaging, RWTH Aachen University

Affiliated withRWTH Aachen University Utrecht University

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 34	2015

Other Publications

Article	Year
Effect of physicochemical modification on the biodistribution and tumor accumulation of HPMA copolymers. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 16274831	2005
Synthesis and characterization of HE-24.8: a polymeric contrast agent for magnetic resonance angiography. Bioconjugate chemistry\| PubMed ID: 16417250	2006
Effect of intratumoral injection on the biodistribution and the therapeutic potential of HPMA copolymer-based drug delivery systems. Neoplasia (New York, N.Y.)\| PubMed ID: 17032495	2006
Effect of radiotherapy and hyperthermia on the tumor accumulation of HPMA copolymer-based drug delivery systems. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 17215057	2007
Specific targeting of tumor angiogenesis by RGD-conjugated ultrasmall superparamagnetic iron oxide particles using a clinical 1.5-T magnetic resonance scanner. Cancer research\| PubMed ID: 17308094	2007
Role of PP2Calpha in cell growth, in radio- and chemosensitivity, and in tumorigenicity. Molecular cancer\| PubMed ID: 17941990	2007
Role of type 2C protein phosphatases in growth regulation and in cellular stress signaling. Critical reviews in biochemistry and molecular biology\| PubMed ID: 18066953	2007
Superparamagnetic iron oxide nanoparticles encapsulated in biodegradable thermosensitive polymeric micelles: toward a targeted nanomedicine suitable for image-guided drug delivery. Langmuir : the ACS journal of surfaces and colloids\| PubMed ID: 19166276	2009
Simultaneous delivery of doxorubicin and gemcitabine to tumors in vivo using prototypic polymeric drug carriers. Biomaterials\| PubMed ID: 19304320	2009
Improving the efficacy of combined modality anticancer therapy using HPMA copolymer-based nanomedicine formulations. Advanced drug delivery reviews\| PubMed ID: 19951732	2010
HPMA copolymers: 30 years of advances. Advanced drug delivery reviews\| PubMed ID: 20005273	2010
Core-crosslinked polymeric micelles with controlled release of covalently entrapped doxorubicin. Biomaterials\| PubMed ID: 20673684	2010
Nanotheranostics and image-guided drug delivery: current concepts and future directions. Molecular pharmaceutics\| PubMed ID: 20822168	2010
Gene silencing activity of siRNA polyplexes based on thiolated N,N,N-trimethylated chitosan. Bioconjugate chemistry\| PubMed ID: 21049986	2010
Gene silencing activity of siRNA polyplexes based on biodegradable polymers. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V\| PubMed ID: 21118719	2011
HPMA-based polymer therapeutics improve the efficacy of surgery, of radiotherapy and of chemotherapy combinations. Nanomedicine (London, England)\| PubMed ID: 21143030	2010
Removable nanocoatings for siRNA polyplexes. Bioconjugate chemistry\| PubMed ID: 21218805	2011
Nanobody-shell functionalized thermosensitive core-crosslinked polymeric micelles for active drug targeting. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 21262289	2011
SiRNA delivery with functionalized carbon nanotubes. International journal of pharmaceutics\| PubMed ID: 21320582	2011
Interaction of liposomes with proteins measured by surface plasmon resonance correlates with their in vivo circulation time. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 21529608	2010
Photochemical internalization (PCI)-mediated enhancement of gene silencing efficiency of polymethacrylates and N,N,N-trimethylated chitosan (TMC) based siRNA polyplexes. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 21529659	2010
Theranostic nanomedicine. Accounts of chemical research\| PubMed ID: 21545096	2011
FMN-coated fluorescent iron oxide nanoparticles for RCP-mediated targeting and labeling of metabolically active cancer and endothelial cells. Biomaterials\| PubMed ID: 21605902	2011
Physicochemical and biological aspects of macrophage-mediated drug targeting in anti-microbial therapy. Fundamental & clinical pharmacology\| PubMed ID: 21631585	2012
Iron oxide nanoparticle-containing microbubble composites as contrast agents for MR and ultrasound dual-modality imaging. Biomaterials\| PubMed ID: 21632103	2011
Reprint of "Nanobody--shell functionalized thermosensitive core-crosslinked polymeric micelles for active drug targeting". Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 21684029	2011
Virtual elastic sphere processing enables reproducible quantification of vessel stenosis at CT and MR angiography. Radiology\| PubMed ID: 21788527	2011
MRI evaluation of the antitumor activity of paramagnetic liposomes loaded with prednisolone phosphate. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences\| PubMed ID: 21896328	2012
Macromolecular nanotheranostics for multimodal anticancer therapy. Nanoscale\| PubMed ID: 21901211	2011
Overcoming cellular multidrug resistance using classical nanomedicine formulations. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences\| PubMed ID: 21907796	2012
Liposomes as carriers for colchicine-derived prodrugs: vascular disrupting nanomedicines with tailorable drug release kinetics. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences\| PubMed ID: 21907797	2012
Polyplexes based on cationic polymers with strong nucleic acid binding properties. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences\| PubMed ID: 21925599	2012
Drug targeting to tumors: principles, pitfalls and (pre-) clinical progress. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 21945285	2012
Comparison of polymeric siRNA nanocarriers in a murine LPS-activated macrophage cell line: gene silencing, toxicity and off-target gene expression. Pharmaceutical research\| PubMed ID: 21971827	2012
Nanomedicine formulations for combination therapies. Nano reviews\| PubMed ID: 22110857	2010
A polymeric colchicinoid prodrug with reduced toxicity and improved efficacy for vascular disruption in cancer therapy. International journal of nanomedicine\| PubMed ID: 22114500	2011
Double-edged role of the CXCL12/CXCR4 axis in experimental myocardial infarction. Journal of the American College of Cardiology\| PubMed ID: 22115649	2011
Theranostic cRGD-BioShuttle Constructs Containing Temozolomide- and Cy7 For NIR-Imaging and Therapy. Theranostics\| PubMed ID: 22211144	2011
Theranostic systems and strategies for monitoring nanomedicine-mediated drug targeting. Current pharmaceutical biotechnology\| PubMed ID: 22214503	2012
Drug targeting systems for inflammatory disease: one for all, all for one. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 22226771	2012
Fluorescent magnetoliposomes as a platform technology for functional and molecular MR and optical imaging. Contrast media & molecular imaging\| PubMed ID: 22344881	2012
Nanomedicine on the move: from monotherapeutic regimens to combination therapies. Expert review of clinical pharmacology\| PubMed ID: 22390552	2012
Ultrasound microbubbles for molecular diagnosis, therapy, and theranostics. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 22393225	2012
MRI-assessed therapeutic effects of locally administered PLGA nanoparticles loaded with anti-inflammatory siRNA in a murine arthritis model. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 22580113	2012
Image-guided, targeted and triggered drug delivery to tumors using polymer-based microbubbles. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 22580225	2012
Drug delivery research in Europe. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 22626515	2012
Glucocorticoid-loaded core-cross-linked polymeric micelles with tailorable release kinetics for targeted therapy of rheumatoid arthritis. Angewandte Chemie (International ed. in English)\| PubMed ID: 22692876	2012
BioShuttle Mobility in Living Cells Studied with High-Resolution FCS & CLSM Methodologies. International journal of medical sciences\| PubMed ID: 22811608	2012
Personalized nanomedicine. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 22829203	2012
Screening of budesonide nanoformulations for treatment of inflammatory bowel disease in an inflamed 3D cell-culture model. ALTEX\| PubMed ID: 22847255	2012
Riboflavin carrier protein-targeted fluorescent USPIO for the assessment of vascular metabolism in tumors. Biomaterials\| PubMed ID: 22959180	2012
Peptide-functionalized gold nanorods increase liver injury in hepatitis. ACS nano\| PubMed ID: 22994679	2012
Combined treatment with recombinant tissue plasminogen activator and dexamethasone phosphate-containing liposomes improves neurological outcome and restricts lesion progression after embolic... Journal of neurochemistry\| PubMed ID: 23050644	2012
Noninvasive optical imaging of nanomedicine biodistribution. ACS nano\| PubMed ID: 23067565	2013
Intrinsically active nanobody-modified polymeric micelles for tumor-targeted combination therapy. Biomaterials\| PubMed ID: 23122804	2013
Non-invasive imaging for studying anti-angiogenic therapy effects. Thrombosis and haemostasis\| PubMed ID: 23407722	2013
Elastin-based molecular MRI of liver fibrosis. Hepatology (Baltimore, Md.)\| PubMed ID: 23424008	2013
Smart drug delivery systems: back to the future vs. clinical reality. International journal of pharmaceutics\| PubMed ID: 23485339	2013
Recent progress in nanomedicine: therapeutic, diagnostic and theranostic applications. Current opinion in biotechnology\| PubMed ID: 23578464	2013
Nondestructive monitoring of tissue-engineered constructs. Biomedizinische Technik. Biomedical engineering\| PubMed ID: 24021591	2014
Rhodamine-loaded intercellular adhesion molecule-1-targeted microbubbles for dual-modality imaging under controlled shear stresses. Circulation. Cardiovascular imaging\| PubMed ID: 24036383	2013
Multidrug resistance: Physiological principles and nanomedical solutions. Advanced drug delivery reviews\| PubMed ID: 24120954	2013
In Vivo Nanotoxicity Testing using the Zebrafish Embryo Assay. Journal of materials chemistry. B, Materials for biology and medicine\| PubMed ID: 24179674	2013
Micro-CT imaging of tumor angiogenesis: quantitative measures describing micromorphology and vascularization. The American journal of pathology\| PubMed ID: 24262753	2014
Recent advances in molecular, multimodal and theranostic ultrasound imaging. Advanced drug delivery reviews\| PubMed ID: 24316070	2014
Nanomedicines for inflammatory arthritis: head-to-head comparison of glucocorticoid-containing polymers, micelles, and liposomes. ACS nano\| PubMed ID: 24341611	2014
Passive versus active tumor targeting using RGD- and NGR-modified polymeric nanomedicines. Nano letters\| PubMed ID: 24422585	2014
PEG-pHPMAm-based polymeric micelles loaded with doxorubicin-prodrugs in combination antitumor therapy with oncolytic vaccinia viruses. Polymer chemistry\| PubMed ID: 24518685	2014
CCL2-dependent infiltrating macrophages promote angiogenesis in progressive liver fibrosis. Gut\| PubMed ID: 24561613	2014
Iron Oxide-labeled Collagen Scaffolds for Non-invasive MR Imaging in Tissue Engineering. Advanced functional materials\| PubMed ID: 24569840	2014
Liposomal encapsulation of dexamethasone modulates cytotoxicity, inflammatory cytokine response, and migratory properties of primary human macrophages. Nanomedicine : nanotechnology, biology, and medicine\| PubMed ID: 24607939	2014
Characterizing EPR-mediated passive drug targeting using contrast-enhanced functional ultrasound imaging. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 24631862	2014
Absolute MR thermometry using nanocarriers. Contrast media & molecular imaging\| PubMed ID: 24706612	2014
The Theranostic Path to Personalized Nanomedicine. Clinical and translational imaging\| PubMed ID: 24860796	2014
Liposomal corticosteroids for the treatment of inflammatory disorders and cancer. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 24878183	2014
Absorption reconstruction improves biodistribution assessment of fluorescent nanoprobes using hybrid fluorescence-mediated tomography. Theranostics\| PubMed ID: 25157277	2014
FMN-coated fluorescent USPIO for cell labeling and non-invasive MR imaging in tissue engineering. Theranostics\| PubMed ID: 25157279	2014
Decationized polyplexes as stable and safe carrier systems for improved biodistribution in systemic gene therapy. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 25204289	2014
Nanoparticles for imaging: top or flop? Radiology\| PubMed ID: 25247562	2014
Decationized polyplexes for gene delivery. Expert opinion on drug delivery\| PubMed ID: 25425332	2015
Fluorescent cell-traceable dexamethasone-loaded liposomes for the treatment of inflammatory liver diseases. Biomaterials\| PubMed ID: 25453965	2015
USPIO-labeled textile materials for non-invasive MR imaging of tissue-engineered vascular grafts. Biomaterials\| PubMed ID: 25465443	2015
Liposomal delivery of dexamethasone attenuates prostate cancer bone metastatic tumor growth In Vivo. The Prostate\| PubMed ID: 25663076	2015
Water-soluble dopamine-based polymers for photoacoustic imaging. Chemical communications (Cambridge, England)\| PubMed ID: 25670068	2015
Theranostic USPIO-Loaded Microbubbles for Mediating and Monitoring Blood-Brain Barrier Permeation. Advanced functional materials\| PubMed ID: 25729344	2015
Enhanced in vitro and in vivo cellular imaging with green tea coated water-soluble iron oxide nanocrystals. ACS applied materials & interfaces\| PubMed ID: 25729881	2015
Fluorescently labeled microbubbles for facilitating translational molecular ultrasound studies. Drug delivery and translational research\| PubMed ID: 25786599	2012
Complete Regression of Xenograft Tumors upon Targeted Delivery of Paclitaxel via Π-Π Stacking Stabilized Polymeric Micelles. ACS nano\| PubMed ID: 25831471	2015
Noninvasive Molecular Ultrasound Monitoring of Vessel Healing After Intravascular Surgical Procedures in a Preclinical Setup. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 25838431	2015
Flexible and modular MPI simulation framework and its use in modelling a μMPI. IEEE transactions on magnetics\| PubMed ID: 25892744	2015
A FIELD CANCELATION SIGNAL EXTRACTION METHOD FOR MAGNETIC PARTICLE IMAGING. IEEE transactions on magnetics\| PubMed ID: 25892745	2015
Core-Crosslinked Polymeric Micelles: Principles, Preparation, Biomedical Applications and Clinical Translation. Nano today\| PubMed ID: 25893004	2015
Fluorophore labeling of core-crosslinked polymeric micelles for multimodal in vivo and ex vivo optical imaging. Nanomedicine (London, England)\| PubMed ID: 25929568	2015
Applications of nanoparticles for diagnosis and therapy of cancer. The British journal of radiology\| PubMed ID: 25969868	2015