synthesis-poly-n-isopropylacrylamide-janus-microhydrogels-for

Synthesis of Poly(<em>N</em>-isopropylacrylamide) Janus Microhydrogels for Anisotropic Thermo-responsiveness and Organophilic/Hydrophilic Loading Capability

Janus microparticles are compartmentalized particles with differing molecular structures and/or functionality on each of their two sides. Because of this ...

Pohang University of Science and Technology (POSTECH)

We report one-step microfluidic synthesis and characterization of novel Janus microhydrogels composed entirely of the same base material, N-isopropylacrylamide (NIPAAm). The microhydrogels were fabricated by the microfluidic generation of Janus monomer microdroplets based on separation of a supersaturated aqueous NIPAAm solution into NIPAAm-rich and -poor phases followed by UV irradiation. The resulting Janus microhydrogels exhibited tunable anisotropic thermo-responsive behavior and organophilic/hydrophilic loading capability.

One-step microfluidic synthesis of Janus microhydrogels with anisotropic thermo-responsive behavior and organophilic/hydrophilic loading capability.

In this paper, we fabricate a flexible and location traceable micromotor, called organo-motor, assisted by microfluidic devices and with high throughput. The organo-motors are composed of organic hydrogel material, poly (ethylene glycol) diacrylate (PEGDA), which can provide the flexibility of their structure. For spatial and temporal traceability of the organo-motors under magnetic resonance imaging (MRI), superparamagnetic iron oxide nanoparticles (SPION; Fe3O4) were incorporated into the PEGDA microhydrogels. Furthermore, a thin layer of platinum (Pt) was deposited onto one side of the SPION-PEGDA microhydrogels providing geometrical asymmetry and catalytic propulsion in aqueous fluids containing hydrogen peroxide solution, H2O2. Furthermore, the motion of the organo-motor was controlled by a small external magnet enabled by the presence of SPION in the motor architecture.

Article	Year
One-step microfluidic synthesis of Janus microhydrogels with anisotropic thermo-responsive behavior and organophilic/hydrophilic loading capability. Langmuir : the ACS journal of surfaces and colloids\| PubMed ID: 24279317	2013
Microfluidic-assisted fabrication of flexible and location traceable organo-motor. IEEE transactions on nanobioscience\| PubMed ID: 25751871	2015

Kyoung Duck Seo

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