Vera Gorbunova

Department of Biology, University of Rochester

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 116	2010
Publication title Cited by 301	2010

Other Publications

Article	Year
CLK-1 protein has DNA binding activity specific to O(L) region of mitochondrial DNA. FEBS letters\| PubMed ID: 11959146	2002
Expression of human telomerase (hTERT) does not prevent stress-induced senescence in normal human fibroblasts but protects the cells from stress-induced apoptosis and necrosis. The Journal of biological chemistry\| PubMed ID: 12140282	2002
Evidence that high telomerase activity may induce a senescent-like growth arrest in human fibroblasts. The Journal of biological chemistry\| PubMed ID: 12496279	2003
Selectable system for monitoring the instability of CTG/CAG triplet repeats in mammalian cells. Molecular and cellular biology\| PubMed ID: 12808091	2003
Telomerase as a growth-promoting factor. Cell cycle (Georgetown, Tex.)\| PubMed ID: 14504469	2003
Phase III study of N,N-diethyl-2-[4-(phenylmethyl) phenoxy]ethanamine (BMS-217380-01) combined with doxorubicin versus doxorubicin alone in metastatic/recurrent breast cancer: National Cance... Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 14722035	2004
DNA end joining becomes less efficient and more error-prone during cellular senescence. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15123826	2004
Genome-wide demethylation destabilizes CTG.CAG trinucleotide repeats in mammalian cells. Human molecular genetics\| PubMed ID: 15459182	2004
Making ends meet in old age: DSB repair and aging. Mechanisms of ageing and development\| PubMed ID: 15888314	2005
Cell divisions are required for L1 retrotransposition. Molecular and cellular biology\| PubMed ID: 17145770	2007
Telomerase activity coevolves with body mass not lifespan. Aging cell\| PubMed ID: 17173545	2007
TRF2 is required for repair of nontelomeric DNA double-strand breaks by homologous recombination. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17670947	2007
Changes in the level and distribution of Ku proteins during cellular senescence. DNA repair\| PubMed ID: 17686666	2007
Changes in DNA repair during aging. Nucleic acids research\| PubMed ID: 17913742	2007
Genome-wide demethylation promotes triplet repeat instability independently of homologous recombination. DNA repair\| PubMed ID: 18083071	2008
Bevacizumab plus interferon alfa-2a for treatment of metastatic renal cell carcinoma: a randomised, double-blind phase III trial. Lancet\| PubMed ID: 18156031	2007
Coevolution of telomerase activity and body mass in mammals: from mice to beavers. Mechanisms of ageing and development\| PubMed ID: 18387652	2009
Comparison of nonhomologous end joining and homologous recombination in human cells. DNA repair\| PubMed ID: 18675941	2008
DNA repair by nonhomologous end joining and homologous recombination during cell cycle in human cells. Cell cycle (Georgetown, Tex.)\| PubMed ID: 18769152	2008
Distinct tumor suppressor mechanisms evolve in rodent species that differ in size and lifespan. Aging cell\| PubMed ID: 18778411	2008
Use of the Rad51 promoter for targeted anti-cancer therapy. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19106292	2008
Rodents for comparative aging studies: from mice to beavers. Age (Dordrecht, Netherlands)\| PubMed ID: 19424861	2008
DNA repair by homologous recombination, but not by nonhomologous end joining, is elevated in breast cancer cells. Neoplasia (New York, N.Y.)\| PubMed ID: 19568413	2009
Doxorubicin and paclitaxel versus fluorouracil, doxorubicin and cyclophosphamide as first-line therapy for women with advanced breast cancer: long-term analysis of the previously published t... Onkologie\| PubMed ID: 19745590	2009
Hypersensitivity to contact inhibition provides a clue to cancer resistance of naked mole-rat. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19858485	2009
Multicenter phase III comparison of cisplatin/S-1 with cisplatin/infusional fluorouracil in advanced gastric or gastroesophageal adenocarcinoma study: the FLAGS trial. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 20159816	2010
SIRT6 promotes DNA repair under stress by activating PARP1. Science (New York, N.Y.)\| PubMed ID: 21680843	2011
SIRT6 overexpression induces massive apoptosis in cancer cells but not in normal cells. Cell cycle (Georgetown, Tex.)\| PubMed ID: 21900744	2011
Repairing split ends: SIRT6, mono-ADP ribosylation and DNA repair. Aging\| PubMed ID: 21946623	2011
Rad51 promoter-targeted gene therapy is effective for in vivo visualization and treatment of cancer. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 22008909	2012
Comparative effectiveness of axitinib versus sorafenib in advanced renal cell carcinoma (AXIS): a randomised phase 3 trial. Lancet\| PubMed ID: 22056247	2011
Safety and efficacy of first-line bevacizumab plus chemotherapy in elderly patients with advanced or recurrent nonsquamous non-small cell lung cancer: safety of avastin in lung trial (MO1939... Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer\| PubMed ID: 22173662	2012
Adenoviral vector driven by a minimal Rad51 promoter is selective for p53-deficient tumor cells. PloS one\| PubMed ID: 22174876	2011
SIRT1 as a therapeutic target in inflammaging of the pulmonary disease. Preventive medicine\| PubMed ID: 22178470	2011
Pharmacogenomics of cisplatin-based chemotherapy in ovarian cancer patients of different ethnic origins. Pharmacogenomics\| PubMed ID: 22188361	2012