Oleh Pochynyuk

Department of Integrative Biology & Pharmacology, University of Texas Health Science Center at Houston

Affiliated withUniversity of Texas Health Science Center at Houston

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 15	2015

Other Publications

Article	Year
Ras couples phosphoinositide 3-OH kinase to the epithelial Na+ channel. Biochimica et biophysica acta\| PubMed ID: 15893513	2005
Identification of a functional phosphatidylinositol 3,4,5-trisphosphate binding site in the epithelial Na+ channel. The Journal of biological chemistry\| PubMed ID: 16154997	2005
Regulation of epithelial Na+ channel activity by conserved serine/threonine switches within sorting signals. The Journal of biological chemistry\| PubMed ID: 16203727	2005
Regulation of the epithelial Na+ channel (ENaC) by phosphatidylinositides. American journal of physiology. Renal physiology\| PubMed ID: 16601296	2006
Rapid translocation and insertion of the epithelial Na+ channel in response to RhoA signaling. The Journal of biological chemistry\| PubMed ID: 16829523	2006
Functional reconstitution of the human epithelial Na+ channel in a mammalian expression system. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 16929934	2006
Binding and direct activation of the epithelial Na+ channel (ENaC) by phosphatidylinositides. The Journal of physiology\| PubMed ID: 17272344	2007
Quantifying RhoA facilitated trafficking of the epithelial Na+ channel toward the plasma membrane with total internal reflection fluorescence-fluorescence recovery after photobleaching. The Journal of biological chemistry\| PubMed ID: 17376773	2007
Acute regulation of the epithelial Na+ channel by phosphatidylinositide 3-OH kinase signaling in native collecting duct principal cells. Journal of the American Society of Nephrology : JASN\| PubMed ID: 17442787	2007
Molecular determinants of PI(4,5)P2 and PI(3,4,5)P3 regulation of the epithelial Na+ channel. The Journal of general physiology\| PubMed ID: 17893193	2007
Purinergic control of apical plasma membrane PI(4,5)P2 levels sets ENaC activity in principal cells. American journal of physiology. Renal physiology\| PubMed ID: 17913833	2008
Ion channel regulation by Ras, Rho, and Rab small GTPases. Experimental biology and medicine (Maywood, N.J.)\| PubMed ID: 17959838	2007
Insight toward epithelial Na+ channel mechanism revealed by the acid-sensing ion channel 1 structure. IUBMB life\| PubMed ID: 18459164	2008
Regulation of the epithelial Na+ channel by endothelin-1 in rat collecting duct. American journal of physiology. Renal physiology\| PubMed ID: 18667482	2008
Physiologic regulation of the epithelial sodium channel by phosphatidylinositides. Current opinion in nephrology and hypertension\| PubMed ID: 18695396	2008
Paracrine regulation of the epithelial Na+ channel in the mammalian collecting duct by purinergic P2Y2 receptor tone. The Journal of biological chemistry\| PubMed ID: 18981175	2008
Thiazolidinedione-induced fluid retention is independent of collecting duct alphaENaC activity. Journal of the American Society of Nephrology : JASN\| PubMed ID: 19158355	2009
Intrinsic voltage dependence of the epithelial Na+ channel is masked by a conserved transmembrane domain tryptophan. The Journal of biological chemistry\| PubMed ID: 19620245	2009
Activation of the epithelial Na+ channel in the collecting duct by vasopressin contributes to water reabsorption. American journal of physiology. Renal physiology\| PubMed ID: 19692483	2009
Dietary Na+ inhibits the open probability of the epithelial sodium channel in the kidney by enhancing apical P2Y2-receptor tone. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 20097874	2010
Endothelin-1 inhibits the epithelial Na+ channel through betaPix/14-3-3/Nedd4-2. Journal of the American Society of Nephrology : JASN\| PubMed ID: 20338996	2010
Purinergic inhibition of ENaC produces aldosterone escape. Journal of the American Society of Nephrology : JASN\| PubMed ID: 20813869	2010
Acute cholesterol-induced anti-natriuretic effects: role of epithelial Na+ channel activity, protein levels, and processing. The Journal of biological chemistry\| PubMed ID: 21041305	2011
Bradykinin acutely inhibits activity of the epithelial Na+ channel in mammalian aldosterone-sensitive distal nephron. American journal of physiology. Renal physiology\| PubMed ID: 21325499	2011
Voltage-dependent gating underlies loss of ENaC function in Pseudohypoaldosteronism type 1. Biophysical journal\| PubMed ID: 21504729	2011
Af17 deficiency increases sodium excretion and decreases blood pressure. Journal of the American Society of Nephrology : JASN\| PubMed ID: 21546577	2011
Purinergic activation of Ca2+-permeable TRPV4 channels is essential for mechano-sensitivity in the aldosterone-sensitive distal nephron. PloS one\| PubMed ID: 21850238	2011
Role of collecting duct AT1a receptors in concentrating urine. Journal of the American Society of Nephrology : JASN\| PubMed ID: 22034643	2011
Angiotensin II increases activity of the epithelial Na+ channel (ENaC) in distal nephron additively to aldosterone. The Journal of biological chemistry\| PubMed ID: 22086923	2012
Function of transient receptor potential cation channel subfamily V member 4 (TRPV4) as a mechanical transducer in flow-sensitive segments of renal collecting duct system. The Journal of biological chemistry\| PubMed ID: 22298783	2012
Salt-dependent inhibition of epithelial Na+ channel-mediated sodium reabsorption in the aldosterone-sensitive distal nephron by bradykinin. Hypertension\| PubMed ID: 23033373	2012
Direct activation of ENaC by angiotensin II: recent advances and new insights. Current hypertension reports\| PubMed ID: 23180052	2013
Novel insights into TRPV4 function in the kidney. Pflügers Archiv : European journal of physiology\| PubMed ID: 23207579	2013
TRPV4 dysfunction promotes renal cystogenesis in autosomal recessive polycystic kidney disease. Journal of the American Society of Nephrology : JASN\| PubMed ID: 23411787	2013
Primary aldosteronism and impaired natriuresis in mice underexpressing TGFβ1. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23503843	2013
Recording ion channels in isolated, split-opened tubules. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 23529443	2013
Ca2+ Imaging as a tool to assess TRP channel function in murine distal nephrons. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 23529445	2013
Discrete control of TRPV4 channel function in the distal nephron by protein kinases A and C. The Journal of biological chemistry\| PubMed ID: 23709216	2013
Direct inhibition of basolateral Kir4.1/5.1 and Kir4.1 channels in the cortical collecting duct by dopamine. American journal of physiology. Renal physiology\| PubMed ID: 23986512	2013
Chronic angiotensin II infusion drives extensive aldosterone-independent epithelial Na+ channel activation. Hypertension\| PubMed ID: 24060890	2013
Direct regulation of ENaC by bradykinin in the distal nephron. Implications for renal sodium handling. Current opinion in nephrology and hypertension\| PubMed ID: 24378775	2014
Emerging role of the calcium-activated, small conductance, SK3 K+ channel in distal tubule function: regulation by TRPV4. PloS one\| PubMed ID: 24762817	2014
IGF-1 and insulin exert opposite actions on ClC-K2 activity in the cortical collecting ducts. American journal of physiology. Renal physiology\| PubMed ID: 25339702	2015
Control of ENaC-mediated sodium reabsorption in the distal nephron by Bradykinin. Vitamins and hormones\| PubMed ID: 25817868	2015