Jochen Klein

Department of Pharmacology, Goethe University of Frankfurt

Affiliated withGoethe University of Frankfurt

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 9	2015

Other Publications

Article	Year
A homeostatic mechanism counteracting K(+) -evoked choline release in adult brain. Journal of neurochemistry\| PubMed ID: 11948248	2002
Dual modulation of striatal acetylcholine release by hyperforin, a constituent of St. John's wort. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 11961077	2002
Breakdown of choline-containing phospholipids in rat brain during severe weight loss. Neuroscience letters\| PubMed ID: 12052529	2002
Stability of phospholipase D in primary astrocytes. Biochemical and biophysical research communications\| PubMed ID: 12270129	2002
NMDA-induced acetylcholine release in mouse striatum: role of NO synthase isoforms. Journal of neurochemistry\| PubMed ID: 12354305	2002
ADP-ribosylation factor-dependent phospholipase D2 activation is required for agonist-induced mu-opioid receptor endocytosis. The Journal of biological chemistry\| PubMed ID: 12519790	2003
Effects of septal grafts on acetylcholine release from rat hippocampus after 192 IgG-saporin lesion. Neurochemical research\| PubMed ID: 12675132	2003
Nitrergic modulation of hippocampal acetylcholine release is independent of endothelial NO synthase activity. Neurochemical research\| PubMed ID: 12675148	2003
Intestinal ischaemia during cardiac arrest and resuscitation: comparative analysis of extracellular metabolites by microdialysis. Resuscitation\| PubMed ID: 12909384	2003
Mitogenic effects of phospholipase D and phosphatidic acid in transiently permeabilized astrocytes: effects of ethanol. Journal of neurochemistry\| PubMed ID: 12969256	2003
Stimulation of hippocampal acetylcholine release by hyperforin, a constituent of St. John's Wort. Neuroscience letters\| PubMed ID: 15196674	2004
Effects of norepinephrine and cardiotrophin-1 on phospholipase D activity and incorporation of myristic acid into phosphatidylcholine in rat heart. Journal of pharmacological sciences\| PubMed ID: 15272209	2004
Glycerophosphocholine is elevated in cerebrospinal fluid of Alzheimer patients. Neurobiology of aging\| PubMed ID: 15465626	2004
Cross-talk between phosphatidic acid and ceramide during ethanol-induced apoptosis in astrocytes. BMC pharmacology\| PubMed ID: 15694004	2005
Microarray analysis and response of the lungs to inhaled insulin. Diabetes technology & therapeutics\| PubMed ID: 15929684	2005
NGP1-01, a lipophilic polycyclic cage amine, is neuroprotective in focal ischemia. Neuroscience letters\| PubMed ID: 15936510	2005
Functions and pathophysiological roles of phospholipase D in the brain. Journal of neurochemistry\| PubMed ID: 16042758	2005
NGP1-01 is a brain-permeable dual blocker of neuronal voltage- and ligand-operated calcium channels. Neurochemical research\| PubMed ID: 16733815	2006
NMDA receptor-antagonistic properties of hyperforin, a constituent of St. John's Wort. Journal of pharmacological sciences\| PubMed ID: 16936454	2006
Effects of chloride flux modulators in an in vitro model of brain edema formation. Brain research\| PubMed ID: 17014830	2006
Role of GABAergic antagonism in the neuroprotective effects of bilobalide. Brain research\| PubMed ID: 17134681	2007
Excessive hippocampal acetylcholine levels in acetylcholinesterase-deficient mice are moderated by butyrylcholinesterase activity. Journal of neurochemistry\| PubMed ID: 17212694	2007
Phenserine. Expert opinion on investigational drugs\| PubMed ID: 17594192	2007
Choline availability and acetylcholine synthesis in the hippocampus of acetylcholinesterase-deficient mice. Neurochemistry international\| PubMed ID: 18023504	2008
Neuroprotection in mice by NGP1-01 after transient focal brain ischemia. Brain research\| PubMed ID: 18234166	2008
Role of glycine receptors and glycine release for the neuroprotective activity of bilobalide. Brain research\| PubMed ID: 18325484	2008
Metabolism of boswellic acids in vitro and in vivo. Drug metabolism and disposition: the biological fate of chemicals\| PubMed ID: 18356270	2008
Effects of rivastigmine and donepezil on brain acetylcholine levels in acetylcholinesterase-deficient mice. Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Société canadienne des sciences pharmaceutiques\| PubMed ID: 19470293	2009
Neurotransmitters and energy metabolites in amyloid-bearing APP(SWE)xPSEN1dE9 Mouse Brain. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 19846589	2010
Nicotine exacerbates brain edema during in vitro and in vivo focal ischemic conditions. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 19889792	2010
Metabolic and transmitter changes in core and penumbra after middle cerebral artery occlusion in mice. Brain research\| PubMed ID: 19961839	2010
Quantitative determination of acetylcholine and choline in microdialysis samples by MALDI-TOF MS. Analytical chemistry\| PubMed ID: 20058877	2010
Acute depression of energy metabolism after microdialysis probe implantation is distinct from ischemia-induced changes in mouse brain. Neurochemical research\| PubMed ID: 20878232	2011
Lactate levels in the brain are elevated upon exposure to volatile anesthetics: a microdialysis study. Neurochemistry international\| PubMed ID: 20933036	2010
The ketogenic diet changes metabolite levels in hippocampal extracellular fluid. Neurochemistry international\| PubMed ID: 21070829	2011
Brain permeability of bilobalide as probed by microdialysis before and after middle cerebral artery occlusion in mice. Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Société canadienne des sciences pharmaceutiques\| PubMed ID: 21486534	2010
In vivo brain microdialysis: advances in neuropsychopharmacology and drug discovery. Expert opinion on drug discovery\| PubMed ID: 21532928	2011
Neuroprotective effects of bilobalide are accompanied by a reduction of ischemia-induced glutamate release in vivo. Brain research\| PubMed ID: 22032877	2011
Ginkgo extract EGb761 confers neuroprotection by reduction of glutamate release in ischemic brain. Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Société canadienne des sciences pharmaceutiques\| PubMed ID: 22365091	2012
Uptake of lithium into rat brain after acute and chronic administration. Neuroscience letters\| PubMed ID: 22659074	2012
Near-complete adaptation of the PRiMA knockout to the lack of central acetylcholinesterase. Journal of neurochemistry\| PubMed ID: 22747514	2012
Mice heterozygous for AChE are more sensitive to AChE inhibitors but do not respond to BuChE inhibition. Neuropharmacology\| PubMed ID: 23147415	2013
Neuroprotective effects of lactate in brain ischemia: dependence on anesthetic drugs. Neurochemistry international\| PubMed ID: 23298645	2013
Blood gases and energy metabolites in mouse blood before and after cerebral ischemia: the effects of anesthetics. Experimental biology and medicine (Maywood, N.J.)\| PubMed ID: 23479767	2013
Neurodegeneration after transient brain ischemia in aged mice: beneficial effects of bilobalide. Brain research\| PubMed ID: 23850645	2013
Phospholipase D is a target for inhibition of astroglial proliferation by ethanol. Neuropharmacology\| PubMed ID: 24262632	2014
Choline acetyltransferase and organic cation transporters are responsible for synthesis and propionate-induced release of acetylcholine in colon epithelium. European journal of pharmacology\| PubMed ID: 24698650	2014
Impaired brain development and reduced cognitive function in phospholipase D-deficient mice. Neuroscience letters\| PubMed ID: 24813107	2014
Bitter triggers acetylcholine release from polymodal urethral chemosensory cells and bladder reflexes. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 24843119	2014
Dynamics of hippocampal acetylcholine release during lithium-pilocarpine-induced status epilepticus in rats. Journal of neurochemistry\| PubMed ID: 24909269	2014
Self-built microdialysis probes with improved recoveries of ATP and neuropeptides. Journal of neuroscience methods\| PubMed ID: 25172804	2014
Detection and Site Localization of Phosphorylcholine-Modified Peptides by NanoLC-ESI-MS/MS Using Precursor Ion Scanning and Multiple Reaction Monitoring Experiments. Journal of the American Society for Mass Spectrometry\| PubMed ID: 25487775	2015
Role of phospholipases D1 and 2 in astroglial proliferation: effects of specific inhibitors and genetic deletion. European journal of pharmacology\| PubMed ID: 25967349	2015