Guoren Deng

Department of Urology, University of California San Francisco

Affiliated withUniversity of California San Francisco VA Medical Center and UCSF

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 16	2015
Publication title Cited by 17	2016

Other Publications

Article	Year
Functional role of DNA mismatch repair gene PMS2 in prostate cancer cells. Oncotarget\| PubMed ID: 26036629	2015
Simultaneous detection of CpG methylation and single nucleotide polymorphism by denaturing high performance liquid chromatography. Nucleic acids research\| PubMed ID: 11809901	2002
Methylation status of promoters and expression of MUC2 and MUC5AC mucins in pancreatic cancer cells. International journal of oncology\| PubMed ID: 12527922	2003
BRAF mutation is frequently present in sporadic colorectal cancer with methylated hMLH1, but not in hereditary nonpolyposis colorectal cancer. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 14734469	2004
Promoter methylation inhibits APC gene expression by causing changes in chromatin conformation and interfering with the binding of transcription factor CCAAT-binding factor. Cancer research\| PubMed ID: 15087381	2004
Mucinous carcinomas of the colorectum have distinct molecular genetic characteristics. International journal of oncology\| PubMed ID: 15703832	2005
The relationship between global methylation level, loss of heterozygosity, and microsatellite instability in sporadic colorectal cancer. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 16361538	2005
BRAF mutation, CpG island methylator phenotype and microsatellite instability occur more frequently and concordantly in mucinous than non-mucinous colorectal cancer. International journal of cancer. Journal international du cancer\| PubMed ID: 16381005	2006
Regional hypermethylation and global hypomethylation are associated with altered chromatin conformation and histone acetylation in colorectal cancer. International journal of cancer. Journal international du cancer\| PubMed ID: 16425274	2006
CpG island methylation is frequently present in tubulovillous and villous adenomas and correlates with size, site, and villous component. Human pathology\| PubMed ID: 17950780	2008
Aberrant expression of SOX2 upregulates MUC5AC gastric foveolar mucin in mucinous cancers of the colorectum and related lesions. International journal of cancer. Journal international du cancer\| PubMed ID: 18027866	2008
Tumor histology helps to identify Lynch syndrome among colorectal cancer patients. Familial cancer\| PubMed ID: 18283560	2008
Proximal and distal colorectal cancers show distinct gene-specific methylation profiles and clinical and molecular characteristics. European journal of cancer (Oxford, England : 1990)\| PubMed ID: 18486467	2008
Clinicopathologic characteristics, CpG island methylator phenotype, and BRAF mutations in microsatellite-stable colorectal cancers without chromosomal instability. Archives of pathology & laboratory medicine\| PubMed ID: 18517279	2008
Aberrant expression of carbohydrate antigens in cancer: the role of genetic and epigenetic regulation. Gastroenterology\| PubMed ID: 18558094	2008
Distinct CpG island methylation profiles and BRAF mutation status in serrated and adenomatous colorectal polyps. International journal of cancer. Journal international du cancer\| PubMed ID: 18798261	2008
Unique methylation pattern of oncostatin m receptor gene in cancers of colorectum and other digestive organs. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 19223499	2009
Combined analysis of minimal residual disease at two time points and its value for risk stratification in childhood B-lineage acute lymphoblastic leukemia. Leukemia research\| PubMed ID: 20034668	2010
Epigenetic changes (aberrant DNA methylation) in colorectal neoplasia. Gut and liver\| PubMed ID: 20485652	2007
Wnt antagonist DKK1 acts as a tumor suppressor gene that induces apoptosis and inhibits proliferation in human renal cell carcinoma. International journal of cancer. Journal international du cancer\| PubMed ID: 20549706	2011
MicroRNA-205-directed transcriptional activation of tumor suppressor genes in prostate cancer. Cancer\| PubMed ID: 20737563	2010
Cytochrome P450 17 (CYP17) is involved in endometrial cancinogenesis through apoptosis and invasion pathways. Molecular carcinogenesis\| PubMed ID: 20886547	2011
MicroRNAs 221/222 and genistein-mediated regulation of ARHI tumor suppressor gene in prostate cancer. Cancer prevention research (Philadelphia, Pa.)\| PubMed ID: 21071579	2011
Regulatory Role of mir-203 in Prostate Cancer Progression and Metastasis. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 21159887	2011
MicroRNA-205 inhibits Src-mediated oncogenic pathways in renal cancer. Cancer research\| PubMed ID: 21330408	2011
MicroRNA-145 is regulated by DNA methylation and p53 gene mutation in prostate cancer. Carcinogenesis\| PubMed ID: 21349819	2011
CASP8AP2 is a promising prognostic indicator in pediatric acute lymphoblastic leukemia. Leukemia research\| PubMed ID: 21696825	2012
Curcumin modulates microRNA-203-mediated regulation of the Src-Akt axis in bladder cancer. Cancer prevention research (Philadelphia, Pa.)\| PubMed ID: 21836020	2011
Catechol-O-methyltransferase-mediated metabolism of 4-hydroxyestradiol inhibits the growth of human renal cancer cells through the apoptotic pathway. Carcinogenesis\| PubMed ID: 22159223	2012
MicroRNA-34a modulates c-Myc transcriptional complexes to suppress malignancy in human prostate cancer cells. PloS one\| PubMed ID: 22235332	2012
Up-regulation of microRNA-21 correlates with lower kidney cancer survival. PloS one\| PubMed ID: 22347428	2012
Loss of heterozygosity, aberrant methylation, BRAF mutation and KRAS mutation in colorectal signet ring cell carcinoma. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc\| PubMed ID: 22522845	2012
miRNA-708 control of CD44(+) prostate cancer-initiating cells. Cancer research\| PubMed ID: 22552290	2012
MicroRNA-124a and microRNA-34b/c are frequently methylated in all histological types of colorectal cancer and polyps, and in the adjacent normal mucosa. Oncology letters\| PubMed ID: 22870149	2011
Genistein suppresses prostate cancer growth through inhibition of oncogenic microRNA-151. PloS one\| PubMed ID: 22928040	2012
MicroRNA-1280 inhibits invasion and metastasis by targeting ROCK1 in bladder cancer. PloS one\| PubMed ID: 23056431	2012
miR-23b represses proto-oncogene Src kinase and functions as methylation-silenced tumor suppressor with diagnostic and prognostic significance in prostate cancer. Cancer research\| PubMed ID: 23074286	2012
miRNA-34b inhibits prostate cancer through demethylation, active chromatin modifications, and AKT pathways. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 23147995	2013
Inhibition of PTEN gene expression by oncogenic miR-23b-3p in renal cancer. PloS one\| PubMed ID: 23189187	2012
MicroRNA-182-5p promotes cell invasion and proliferation by down regulating FOXF2, RECK and MTSS1 genes in human prostate cancer. PloS one\| PubMed ID: 23383207	2013
Genistein up-regulates tumor suppressor microRNA-574-3p in prostate cancer. PloS one\| PubMed ID: 23554959	2013
Hrk mediates 2-methoxyestradiol-induced mitochondrial apoptotic signaling in prostate cancer cells. Molecular cancer therapeutics\| PubMed ID: 23580416	2013
MicroRNA-23b functions as a tumor suppressor by regulating Zeb1 in bladder cancer. PloS one\| PubMed ID: 23844063	2013
MicroRNA-4723 inhibits prostate cancer growth through inactivation of the Abelson family of nonreceptor protein tyrosine kinases. PloS one\| PubMed ID: 24223753	2013
Long non-coding RNA HOTAIR is targeted and regulated by miR-141 in human cancer cells. The Journal of biological chemistry\| PubMed ID: 24616104	2014
Effect of microRNA-210 on prognosis and response to chemotherapeutic drugs in pediatric acute lymphoblastic leukemia. Cancer science\| PubMed ID: 24720529	2014
Regulation of SRC kinases by microRNA-3607 located in a frequently deleted locus in prostate cancer. Molecular cancer therapeutics\| PubMed ID: 24817628	2014
Cytochrome P450 1B1 polymorphisms and risk of renal cell carcinoma in men. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine\| PubMed ID: 25027399	2014
DNMT3A mutations and prognostic significance in childhood acute lymphoblastic leukemia. Leukemia & lymphoma\| PubMed ID: 25242092	2015
DNA mismatch repair gene MLH1 induces apoptosis in prostate cancer cells. Oncotarget\| PubMed ID: 25526032	2014
Long Noncoding RNA MALAT1 Promotes Aggressive Renal Cell Carcinoma through Ezh2 and Interacts with miR-205. Cancer research\| PubMed ID: 25600645	2015
Inactivation of bone morphogenetic protein 2 may predict clinical outcome and poor overall survival for renal cell carcinoma through epigenetic pathways. Oncotarget\| PubMed ID: 25797254	2015
CYP1B1 promotes tumorigenesis via altered expression of CDC20 and DAPK1 genes in renal cell carcinoma. BMC cancer\| PubMed ID: 26626260	2015
Functional role and tobacco smoking effects on methylation of CYP1A1 gene in prostate cancer. Oncotarget\| PubMed ID: 27203547	2016