Deborah A. Howatt

Saha Cardiovascular Research Center, University of Kentucky

Research Area

Biography

Deborah A. Howatt has not added Biography.
If you are Deborah A. Howatt and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 84	2015

Other Publications

Article	Year
Aldosterone does not mediate angiotensin II-induced atherosclerosis and abdominal aortic aneurysms. British journal of pharmacology\| PubMed ID: 15655500	2005
Angiotensin II infusion induces site-specific intra-laminar hemorrhage in macrophage colony-stimulating factor-deficient mice. Atherosclerosis\| PubMed ID: 16153649	2006
Rapid dilation of the abdominal aorta during infusion of angiotensin II detected by noninvasive high-frequency ultrasonography. Journal of vascular surgery : official publication, the Society for Vascular Surgery [and] International Society for Cardiovascular Surgery, North American Chapter\| PubMed ID: 16890871	2006
Interferon-gamma and the interferon-inducible chemokine CXCL10 protect against aneurysm formation and rupture. Circulation\| PubMed ID: 19139386	2009
ANG II infusion promotes abdominal aortic aneurysms independent of increased blood pressure in hypercholesterolemic mice. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 19252100	2009
Modes of defining atherosclerosis in mouse models: relative merits and evolving standards. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 19763919	2009
Angiotensin II infusion promotes ascending aortic aneurysms: attenuation by CCR2 deficiency in apoE-/- mice. Clinical science (London, England : 1979)\| PubMed ID: 20088827	2010
Dietary coenzyme Q10 does not protect against cigarette smoke-augmented atherosclerosis in apoE-deficient mice. Free radical biology & medicine\| PubMed ID: 20227489	2010
Deficiency of the NR4A orphan nuclear receptor NOR1 decreases monocyte adhesion and atherosclerosis. Circulation research\| PubMed ID: 20558821	2010
Group X secretory phospholipase A(2) augments angiotensin II-induced inflammatory responses and abdominal aortic aneurysm formation in apoE-deficient mice. Atherosclerosis\| PubMed ID: 20833395	2011
Telomerase deficiency in bone marrow-derived cells attenuates angiotensin II-induced abdominal aortic aneurysm formation. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 21088250	2011
Angiotensin-converting enzyme 2 deficiency in whole body or bone marrow-derived cells increases atherosclerosis in low-density lipoprotein receptor-/- mice. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 21252069	2011
Endothelial cell-specific deficiency of Ang II type 1a receptors attenuates Ang II-induced ascending aortic aneurysms in LDL receptor-/- mice. Circulation research\| PubMed ID: 21252156	2011
Prolonged infusion of angiotensin II in apoE(-/-) mice promotes macrophage recruitment with continued expansion of abdominal aortic aneurysm. The American journal of pathology\| PubMed ID: 21763672	2011
MyD88 deficiency attenuates angiotensin II-induced abdominal aortic aneurysm formation independent of signaling through Toll-like receptors 2 and 4. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 21960563	2011
Calpain inhibition attenuates angiotensin II-induced abdominal aortic aneurysms and atherosclerosis in low-density lipoprotein receptor-deficient mice. Journal of cardiovascular pharmacology\| PubMed ID: 21964156	2012
Comparative effects of different modes of renin angiotensin system inhibition on hypercholesterolaemia-induced atherosclerosis. British journal of pharmacology\| PubMed ID: 22014125	2011
Deficiency of receptor-associated protein attenuates angiotensin II-induced atherosclerosis in hypercholesterolemic mice without influencing abdominal aortic aneurysms. Atherosclerosis\| PubMed ID: 22153700	2012
Atherogenic and pulmonary responses of ApoE- and LDL receptor-deficient mice to sidestream cigarette smoke. Toxicology\| PubMed ID: 22659316	2012
Differential effects of dietary sodium intake on blood pressure and atherosclerosis in hypercholesterolemic mice. The Journal of nutritional biochemistry\| PubMed ID: 22705323	2013
Doxycycline does not influence established abdominal aortic aneurysms in angiotensin II-infused mice. PloS one\| PubMed ID: 23029514	2012
Regional variation in aortic AT1b receptor mRNA abundance is associated with contractility but unrelated to atherosclerosis and aortic aneurysms. PloS one\| PubMed ID: 23119030	2012
Depletion of endothelial or smooth muscle cell-specific angiotensin II type 1a receptors does not influence aortic aneurysms or atherosclerosis in LDL receptor deficient mice. PloS one\| PubMed ID: 23236507	2012
PD123319 augments angiotensin II-induced abdominal aortic aneurysms through an AT2 receptor-independent mechanism. PloS one\| PubMed ID: 23593499	2013
High density lipoprotein protects against polymicrobe-induced sepsis in mice. The Journal of biological chemistry\| PubMed ID: 23658016	2013
Calpain-2 compensation promotes angiotensin II-induced ascending and abdominal aortic aneurysms in calpain-1 deficient mice. PloS one\| PubMed ID: 23977256	2013
Amlodipine reduces AngII-induced aortic aneurysms and atherosclerosis in hypercholesterolemic mice. PloS one\| PubMed ID: 24244746	2013
Deficiency of endogenous acute phase serum amyloid A does not affect atherosclerotic lesions in apolipoprotein E-deficient mice. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 24265416	2014
Scavenger receptor BI and high-density lipoprotein regulate thymocyte apoptosis in sepsis. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 24603680	2014
Angiotensin II induces region-specific medial disruption during evolution of ascending aortic aneurysms. The American journal of pathology\| PubMed ID: 25038458	2014
Angiotensin-converting enzyme 2 decreases formation and severity of angiotensin II-induced abdominal aortic aneurysms. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 25301841	2014
Smooth muscle cell deletion of low-density lipoprotein receptor-related protein 1 augments angiotensin II-induced superior mesenteric arterial and ascending aortic aneurysms. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 25395615	2015
Cys18-Cys137 disulfide bond in mouse angiotensinogen does not affect AngII-dependent functions in vivo. Hypertension\| PubMed ID: 25691624	2015
Deficiency of Endogenous Acute-Phase Serum Amyloid A Protects apoE-/- Mice From Angiotensin II-Induced Abdominal Aortic Aneurysm Formation. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 25745063	2015
Increasing adipocyte lipoprotein lipase improves glucose metabolism in high fat diet-induced obesity. The Journal of biological chemistry\| PubMed ID: 25784555	2015
Associations of ApoAI and ApoB-Containing Lipoproteins With AngII-Induced Abdominal Aortic Aneurysms in Mice. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 26044581	2015
Fibroblast Angiotensin II Type 1a Receptors Contribute to Angiotensin II-Induced Medial Hyperplasia in the Ascending Aorta. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 26160957	2015