Markus Heilig

Center for Social and Affective Neuroscience, linköping university

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 21	2017
Publication title Cited by 7	2019

Other Publications

Article	Year
[Documented effect of methadone, but not naltrexone]. Lakartidningen\| PubMed ID: 11881232	2002
Long-lasting increase in voluntary ethanol consumption and transcriptional regulation in the rat brain after intermittent exposure to alcohol. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 11772933	2002
[Surprising conclusion by the SBU concerning the benefits of naltrexone in the treatment of heroin dependence]. Lakartidningen\| PubMed ID: 11838078	2002
Anxiogenic-like action of centrally administered glucagon-like peptide-1 in a punished drinking test. Progress in neuro-psychopharmacology & biological psychiatry\| PubMed ID: 11853101	2002
Brain neuropeptide Y (NPY) in stress and alcohol dependence. Reviews in the neurosciences\| PubMed ID: 12013027	2002
[The brain behind stress and fatigue depression]. Lakartidningen\| PubMed ID: 12092052	2002
The dual-diagnosis concept used by Swedish social workers: limited validity upon examination using a structured diagnostic approach. European psychiatry : the journal of the Association of European Psychiatrists\| PubMed ID: 12457747	2002
NPY Leu7Pro and alcohol dependence in Finnish and Swedish populations. Alcoholism, clinical and experimental research\| PubMed ID: 12544000	2003
Neuropeptide y and alcoholism: genetic, molecular, and pharmacological evidence. Alcoholism, clinical and experimental research\| PubMed ID: 12605064	2003
1-year retention and social function after buprenorphine-assisted relapse prevention treatment for heroin dependence in Sweden: a randomised, placebo-controlled trial. Lancet (London, England)\| PubMed ID: 12606177	2003
[Researchers and psychiatrists defending Gillberg's research on ADDH: Karfve's campaign is a form of personal persecution and scientific basis is missing]. Lakartidningen\| PubMed ID: 12640980	2003
Persistent behavioral and autonomic supersensitivity to stress following prenatal stress exposure in rats. Behavioural brain research\| PubMed ID: 12644280	2003
[Ecstasy is a dangerous drug the society chooses to ignore]. Lakartidningen\| PubMed ID: 12674555	2003
Behavioural analysis of melanin-concentrating hormone in rats: evidence for orexigenic and anxiolytic properties. Regulatory peptides\| PubMed ID: 12832098	2003
A temporal threshold for induction of persistent alcohol preference: behavioral evidence in a rat model of intermittent intoxication. Journal of studies on alcohol\| PubMed ID: 12921185	2003
[Reduced drug craving and better social function with buprenorphine therapy. Combination therapy as an alternative to methadone therapy in heroin addiction]. Lakartidningen\| PubMed ID: 12959012	2003
Corticotropin-releasing hormone (CRH) mRNA expression in rat central amygdala in cannabinoid tolerance and withdrawal: evidence for an allostatic shift? Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology\| PubMed ID: 12968131	2004
Neuropeptide systems as novel therapeutic targets for depression and anxiety disorders. Trends in pharmacological sciences\| PubMed ID: 14607081	2003
Fetus at risk: prevalence of alcohol consumption during pregnancy estimated with a simple screening method in Swedish antenatal clinics. Addiction (Abingdon, England)\| PubMed ID: 14616177	2003
Attenuation of ethanol self-administration and of conditioned reinstatement of alcohol-seeking behaviour by the antiopioid peptide nociceptin/orphanin FQ in alcohol-preferring rats. Psychopharmacology\| PubMed ID: 14624331	2004
Decreased cerebrospinal fluid neuropeptide Y (NPY) in patients with treatment refractory unipolar major depression: preliminary evidence for association with preproNPY gene polymorphism. Journal of psychiatric research\| PubMed ID: 14757324	2004
Analysis of 5-hydroxytryptamine 2c receptor gene promoter variants as alcohol-dependence risk factors. Alcohol and alcoholism (Oxford, Oxfordshire)\| PubMed ID: 15304380	2004
Beliefs and reality: detection and prevention of high alcohol consumption in Swedish antenatal clinics. Acta obstetricia et gynecologica Scandinavica\| PubMed ID: 15315589	2004
High trait anxiety and hyporeactivity to stress of the dorsomedial prefrontal cortex: a combined phMRI and Fos study in rats. NeuroImage\| PubMed ID: 15325386	2004
The NPY system in stress, anxiety and depression. Neuropeptides\| PubMed ID: 15337373	2004
Increased attributable risk related to a functional mu-opioid receptor gene polymorphism in association with alcohol dependence in central Sweden. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology\| PubMed ID: 15525999	2005
Functional genomics strategies to identify susceptibility genes and treatment targets in alcohol dependence. Neurotoxicity research\| PubMed ID: 15545019	2004
Suppression of ethanol self-administration by the neuropeptide Y (NPY) Y2 receptor antagonist BIIE0246: evidence for sensitization in rats with a history of dependence. Neuroscience letters\| PubMed ID: 15670655	2005
Anxiolytic-like actions of centrally-administered neuropeptide Y, but not galanin, in C57BL/6J mice. Pharmacology, biochemistry, and behavior\| PubMed ID: 15740785	2005
Cannabinoid CB1 receptor antagonism reduces conditioned reinstatement of ethanol-seeking behavior in rats. The European journal of neuroscience\| PubMed ID: 15869521	2005
A novel single nucleotide polymorphism of the neuropeptide Y (NPY) gene associated with alcohol dependence. Alcoholism, clinical and experimental research\| PubMed ID: 15897713	2005
Unexpectedly high prevalence of alcohol use among pregnant Swedish women: failed detection by antenatal care and simple tools that improve detection. Journal of studies on alcohol\| PubMed ID: 15957666	2005
Gene discovery in neuropharmacological and behavioral studies using Affymetrix microarray data. Methods (San Diego, Calif.)\| PubMed ID: 16308151	2005
Addiction and its brain science. Addiction (Abingdon, England)\| PubMed ID: 16367982	2005
NPY in alcoholism and psychiatric disorders. EXS\| PubMed ID: 16383007	2006
Genetic impairment of frontocortical endocannabinoid degradation and high alcohol preference. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology\| PubMed ID: 16482090	2007
Buprenorphine reduces alcohol drinking through activation of the nociceptin/orphanin FQ-NOP receptor system. Biological psychiatry\| PubMed ID: 16533497	2007
Pharmacological treatment of alcohol dependence: target symptoms and target mechanisms. Pharmacology & therapeutics\| PubMed ID: 16545872	2006
Identifying hazardous alcohol consumption during pregnancy: implementing a research-based model in real life. Acta obstetricia et gynecologica Scandinavica\| PubMed ID: 16752255	2006
Neuroendocrine, cognitive and structural imaging characteristics of women on longterm sickleave with job stress-induced depression. Biological psychiatry\| PubMed ID: 16934773	2006
Association of a functional polymorphism in the mu-opioid receptor gene with alcohol response and consumption in male rhesus macaques. Archives of general psychiatry\| PubMed ID: 17339526	2007
3-(4-Chloro-2-morpholin-4-yl-thiazol-5-yl)-8-(1-ethylpropyl)-2,6-dimethyl-imidazo[1,2-b]pyridazine: a novel brain-penetrant, orally available corticotropin-releasing factor receptor 1 antago... The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 17344409	2007
Hazardous alcohol users during pregnancy: psychiatric health and personality traits. Drug and alcohol dependence\| PubMed ID: 17363194	2007
Region-specific down-regulation of Crhr1 gene expression in alcohol-preferring msP rats following ad lib access to alcohol. Addiction biology\| PubMed ID: 17407495	2007
A stepped care strategy using buprenorphine and methadone versus conventional methadone maintenance in heroin dependence: a randomized controlled trial. The American journal of psychiatry\| PubMed ID: 17475739	2007
Effect of the adenosine A2a receptor antagonist 3,7-dimethyl-propargylxanthine on anxiety-like and depression-like behavior and alcohol consumption in Wistar Rats. Alcoholism, clinical and experimental research\| PubMed ID: 17550371	2007
Upregulation of voluntary alcohol intake, behavioral sensitivity to stress, and amygdala crhr1 expression following a history of dependence. Biological psychiatry\| PubMed ID: 17585886	2008
A key role for corticotropin-releasing factor in alcohol dependence. Trends in neurosciences\| PubMed ID: 17629579	2007
Long-lasting tolerance to alcohol following a history of dependence. Addiction biology\| PubMed ID: 17850416	2008
Mood and neuroendocrine response to a chemical stressor, metyrapone, in buprenorphine-maintained heroin dependence. Biological psychiatry\| PubMed ID: 17850768	2008
The neuropeptide Y Y1 receptor subtype is necessary for the anxiolytic-like effects of neuropeptide Y, but not the antidepressant-like effects of fluoxetine, in mice. Psychopharmacology\| PubMed ID: 17891380	2008
Changes in the occurrences of coercive interventions and staff injuries on a psychiatric intensive care unit. Archives of psychiatric nursing\| PubMed ID: 17904484	2007
Association between the recombinant human serotonin transporter linked promoter region polymorphism and behavior in rhesus macaques during a separation paradigm. Development and psychopathology\| PubMed ID: 17931429	2007
Imagen: implications for addiction science and science policy. Addiction (Abingdon, England)\| PubMed ID: 17935578	2007
Association between the nociceptin receptor gene (OPRL1) single nucleotide polymorphisms and alcohol dependence. Addiction biology\| PubMed ID: 18269382	2008
Neurokinin 1 receptor antagonism as a possible therapy for alcoholism. Science (New York, N.Y.)\| PubMed ID: 18276852	2008
Buprenorphine and methadone treatment of opiate dependence during pregnancy: comparison of fetal growth and neonatal outcomes in two consecutive case series. Drug and alcohol dependence\| PubMed ID: 18355989	2008
Dysregulation of nociceptin/orphanin FQ activity in the amygdala is linked to excessive alcohol drinking in the rat. Biological psychiatry\| PubMed ID: 18367152	2008
Variation at the mu-opioid receptor gene (OPRM1) influences attachment behavior in infant primates. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18378897	2008
Neuroplasticity in brain reward circuitry following a history of ethanol dependence. The European journal of neuroscience\| PubMed ID: 18412612	2008
Rapid tolerance and locomotor sensitization in ethanol-naïve adolescent rhesus macaques. Alcoholism, clinical and experimental research\| PubMed ID: 18482160	2008
Loss of glial glutamate and aspartate transporter (excitatory amino acid transporter 1) causes locomotor hyperactivity and exaggerated responses to psychotomimetics: rescue by haloperidol an... Biological psychiatry\| PubMed ID: 18550032	2008
CRH haplotype as a factor influencing cerebrospinal fluid levels of corticotropin-releasing hormone, hypothalamic-pituitary-adrenal axis activity, temperament, and alcohol consumption in rhe... Archives of general psychiatry\| PubMed ID: 18678798	2008
Acute ethanol challenge inhibits glycogen synthase kinase-3beta in the rat prefrontal cortex. The international journal of neuropsychopharmacology\| PubMed ID: 19007447	2009
[New guidelines against unfair treatment of narcotic addicts necessary]. Lakartidningen\| PubMed ID: 19031975	2008
Suppressed neuroendocrine stress response in depressed women on job-stress-related long-term sick leave: a stable marker potentially suggestive of preexisting vulnerability. Biological psychiatry\| PubMed ID: 19058782	2009
Assessment of glutamate transporter GLAST (EAAT1)-deficient mice for phenotypes relevant to the negative and executive/cognitive symptoms of schizophrenia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology\| PubMed ID: 19078949	2009
Arrestin3 mediates D(2) dopamine receptor internalization. Synapse (New York, N.Y.)\| PubMed ID: 19309759	2009
Persistent increase of alcohol-seeking evoked by neuropeptide S: an effect mediated by the hypothalamic hypocretin system. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology\| PubMed ID: 19322167	2009
Requirement of central ghrelin signaling for alcohol reward. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19564604	2009
Functional CRH variation increases stress-induced alcohol consumption in primates. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19706546	2009
Suppression of alcohol preference by naltrexone in the rhesus macaque: a critical role of genetic variation at the micro-opioid receptor gene locus. Biological psychiatry\| PubMed ID: 19748082	2010
Rimonabant (SR141716) has no effect on alcohol self-administration or endocrine measures in nontreatment-seeking heavy alcohol drinkers. Psychopharmacology\| PubMed ID: 19902183	2010
Stress-related neuropeptides and alcoholism: CRH, NPY, and beyond. Alcohol (Fayetteville, N.Y.)\| PubMed ID: 19913192	2009
Translating the neuroscience of alcoholism into clinical treatments: from blocking the buzz to curing the blues. Neuroscience and biobehavioral reviews\| PubMed ID: 19941895	2010
Neuropeptide Y (NPY) suppresses yohimbine-induced reinstatement of alcohol seeking. Psychopharmacology\| PubMed ID: 20012021	2010
Gene-environment interactions and response to social intrusion in male and female rhesus macaques. Biological psychiatry\| PubMed ID: 20015482	2010
D2 dopamine receptor internalization prolongs the decrease of radioligand binding after amphetamine: a PET study in a receptor internalization-deficient mouse model. NeuroImage\| PubMed ID: 20097293	2010
Neurokinin-1 receptors (NK1R:s), alcohol consumption, and alcohol reward in mice. Psychopharmacology\| PubMed ID: 20112009	2010
Alcohol response and consumption in adolescent rhesus macaques: life history and genetic influences. Alcohol (Fayetteville, N.Y.)\| PubMed ID: 20113875	2010
Alcohol-induced neurodegeneration, suppression of transforming growth factor-beta, and cognitive impairment in rats: prevention by group II metabotropic glutamate receptor activation. Biological psychiatry\| PubMed ID: 20132926	2010
Ethanol consumption: how should we measure it? Achieving consilience between human and animal phenotypes. Addiction biology\| PubMed ID: 20148775	2010
Reward sensitivity: issues of measurement, and achieving consilience between human and animal phenotypes. Addiction biology\| PubMed ID: 20148777	2010
Acute withdrawal, protracted abstinence and negative affect in alcoholism: are they linked? Addiction biology\| PubMed ID: 20148778	2010
Effects of early-life stress on serotonin(1A) receptors in juvenile Rhesus monkeys measured by positron emission tomography. Biological psychiatry\| PubMed ID: 20172506	2010
Early onset alcohol dependence with high density of family history is not "male limited". Alcohol (Fayetteville, N.Y.)\| PubMed ID: 20193873	2010
A multiplex calcium assay for identification of GPCR agonists and antagonists. Assay and drug development technologies\| PubMed ID: 20230302	2010
Long-term suppression of forebrain neurogenesis and loss of neuronal progenitor cells following prolonged alcohol dependence in rats. The international journal of neuropsychopharmacology\| PubMed ID: 20334723	2010
Functional NPY variation as a factor in stress resilience and alcohol consumption in rhesus macaques. Archives of general psychiatry\| PubMed ID: 20368518	2010
Ethanol-induced activation of AKT and DARPP-32 in the mouse striatum mediated by opioid receptors. Addiction biology\| PubMed ID: 20456289	2010
Addiction research centres and the nurturing of creativity: the National Institute on Alcohol Abuse and Alcoholism. Addiction (Abingdon, England)\| PubMed ID: 20569230	2011
Suppression of alcohol self-administration and reinstatement of alcohol seeking by melanin-concentrating hormone receptor 1 (MCH1-R) antagonism in Wistar rats. Psychopharmacology\| PubMed ID: 20628734	2010
Human NPY promoter variation rs16147:T>C as a moderator of prefrontal NPY gene expression and negative affect. Human mutation\| PubMed ID: 20648632	2010
Reversibility of object recognition but not spatial memory impairment following binge-like alcohol exposure in rats. Neurobiology of learning and memory\| PubMed ID: 20849966	2010
Effect of acamprosate on magnetic resonance spectroscopy measures of central glutamate in detoxified alcohol-dependent individuals: a randomized controlled experimental medicine study. Archives of general psychiatry\| PubMed ID: 20921123	2010
Chronic alcohol neuroadaptation and stress contribute to susceptibility for alcohol craving and relapse. Pharmacology & therapeutics\| PubMed ID: 20951730	2011
Neuropeptide S facilitates cue-induced relapse to cocaine seeking through activation of the hypothalamic hypocretin system. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 20974945	2010
Selective Modulation of Gq/Gs pathways by Naphtho Pyrano Pyrimidines as antagonists of the Neuropeptide S Receptor. ACS chemical neuroscience\| PubMed ID: 21116448	2010
The novel, selective, brain-penetrant neuropeptide Y Y2 receptor antagonist, JNJ-31020028, tested in animal models of alcohol consumption, relapse, and anxiety. Alcohol (Fayetteville, N.Y.)\| PubMed ID: 21145691	2011
Genetic moderators and psychiatric mediators of the link between sexual abuse and alcohol dependence. Drug and alcohol dependence\| PubMed ID: 21193270	2011
Increased mRNA Levels of TCF7L2 and MYC of the Wnt Pathway in Tg-ArcSwe Mice and Alzheimer's Disease Brain. International journal of Alzheimer's disease\| PubMed ID: 21234373	2010
Dissociation of antidepressant-like activity of escitalopram and nortriptyline on behaviour and hippocampal BDNF expression in female rats. Journal of psychopharmacology (Oxford, England)\| PubMed ID: 21262856	2011
Activation of nuclear PPARγ receptors by the antidiabetic agent pioglitazone suppresses alcohol drinking and relapse to alcohol seeking. Biological psychiatry\| PubMed ID: 21276964	2011
Pharmacologically induced alcohol craving in treatment seeking alcoholics correlates with alcoholism severity, but is insensitive to acamprosate. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology\| PubMed ID: 21289601	2011
Child Î¼-opioid receptor gene variant influences parent-child relations. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology\| PubMed ID: 21326192	2011
Stress-induced reinstatement of alcohol-seeking in rats is selectively suppressed by the neurokinin 1 (NK1) antagonist L822429. Psychopharmacology\| PubMed ID: 21340476	2011
Exposure to nicotine during periadolescence or early adulthood alters aversive and physiological effects induced by ethanol. Pharmacology, biochemistry, and behavior\| PubMed ID: 21420998	2011
OPRM1 gene variation influences hypothalamic-pituitary-adrenal axis function in response to a variety of stressors in rhesus macaques. Psychoneuroendocrinology\| PubMed ID: 21459516	2011
A welcome change that stops short of being fully satisfying. Addiction (Abingdon, England)\| PubMed ID: 21477231	2011
Translational and reverse translational research on the role of stress in drug craving and relapse. Psychopharmacology\| PubMed ID: 21494792	2011
Translational approaches to medication development. Current topics in behavioral neurosciences\| PubMed ID: 21590390	2013
The biometric measurement of alcohol consumption. Alcoholism, clinical and experimental research\| PubMed ID: 21895709	2012
Pharmacological consequence of the A118G Î¼ opioid receptor polymorphism on morphine- and fentanyl-mediated modulation of CaÂ²âº channels in humanized mouse sensory neurons. Anesthesiology\| PubMed ID: 21926562	2011
The G protein coupled receptor Gpr153 shares common evolutionary origin with Gpr162 and is highly expressed in central regions including the thalamus, cerebellum and the arcuate nucleus. The FEBS journal\| PubMed ID: 21981325	2011
Relationship between liver function and brain shrinkage in patients with alcohol dependence. Alcoholism, clinical and experimental research\| PubMed ID: 21995416	2012
Pharmacogenetic approaches to the treatment of alcohol addiction. Nature reviews. Neuroscience\| PubMed ID: 22011682	2011
Pharmacological blockade of corticotropin-releasing hormone receptor 1 (CRH1R) reduces voluntary consumption of high alcohol concentrations in non-dependent Wistar rats. Pharmacology, biochemistry, and behavior\| PubMed ID: 22036774	2012
Brain-specific inactivation of the Crhr1 gene inhibits post-dependent and stress-induced alcohol intake, but does not affect relapse-like drinking. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology\| PubMed ID: 22113086	2012
Effects of the NK1 antagonist, aprepitant, on response to oral and intranasal oxycodone in prescription opioid abusers. Addiction biology\| PubMed ID: 22260216	2013
The serotonin transporter gene linked polymorphic region is associated with the behavioral response to repeated stress exposure in infant rhesus macaques. Development and psychopathology\| PubMed ID: 22293001	2012
Reduced alcohol intake and reward associated with impaired endocannabinoid signaling in mice with a deletion of the glutamate transporter GLAST. Neuropharmacology\| PubMed ID: 22342743	2012
Impact of multiple types of childhood trauma exposure on risk of psychiatric comorbidity among alcoholic inpatients. Alcoholism, clinical and experimental research\| PubMed ID: 22420670	2012
Medications development to treat alcohol dependence: a vision for the next decade. Addiction biology\| PubMed ID: 22458728	2012
Binge-like ethanol consumption increases corticosterone levels and neurodegneration whereas occupancy of type II glucocorticoid receptors with mifepristone is neuroprotective. Addiction biology\| PubMed ID: 22500955	2014
The kappa opioid receptor antagonist JDTic attenuates alcohol seeking and withdrawal anxiety. Addiction biology\| PubMed ID: 22515275	2012
Corticosteroid-dependent plasticity mediates compulsive alcohol drinking in rats. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 22649234	2012
Melanin-concentrating hormone receptor 1 (MCH1-R) antagonism: reduced appetite for calories and suppression of addictive-like behaviors. Pharmacology, biochemistry, and behavior\| PubMed ID: 22705492	2012
Stress-related neuropeptides and addictive behaviors: beyond the usual suspects. Neuron\| PubMed ID: 23040815	2012
Enhanced GABAergic transmission in the central nucleus of the amygdala of genetically selected Marchigian Sardinian rats: alcohol and CRF effects. Neuropharmacology\| PubMed ID: 23220399	2013
Childhood trauma exposure and alcohol dependence severity in adulthood: mediation by emotional abuse severity and neuroticism. Alcoholism, clinical and experimental research\| PubMed ID: 23278300	2013
Behavioral, biological, and chemical perspectives on targeting CRF(1) receptor antagonists to treat alcoholism. Drug and alcohol dependence\| PubMed ID: 23294766	2013
The NK1 receptor antagonist L822429 reduces heroin reinforcement. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology\| PubMed ID: 23303056	2013
Low vitamin D status and suicide: a case-control study of active duty military service members. PloS one\| PubMed ID: 23308099	2013
Rescue of infralimbic mGluR2 deficit restores control over drug-seeking behavior in alcohol dependence. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 23407939	2013
Conditioned preference to a methamphetamine-associated contextual cue in humans. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology\| PubMed ID: 23416857	2013
Tacr1 gene variation and neurokinin 1 receptor expression is associated with antagonist efficacy in genetically selected alcohol-preferring rats. Biological psychiatry\| PubMed ID: 23419547	2013
Activation of PPARγ by pioglitazone potentiates the effects of naltrexone on alcohol drinking and relapse in msP rats. Alcoholism, clinical and experimental research\| PubMed ID: 23550625	2013
Role of a genetic polymorphism in the corticotropin-releasing factor receptor 1 gene in alcohol drinking and seeking behaviors of marchigian sardinian alcohol-preferring rats. Frontiers in psychiatry\| PubMed ID: 23630503	2013
A novel brain penetrant NPS receptor antagonist, NCGC00185684, blocks alcohol-induced ERK-phosphorylation in the central amygdala and decreases operant alcohol self-administration in rats. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 23761908	2013
β-Arrestin 2 knockout mice exhibit sensitized dopamine release and increased reward in response to a low dose of alcohol. Psychopharmacology\| PubMed ID: 23779257	2013
Loss of metabotropic glutamate receptor 2 escalates alcohol consumption. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 24082084	2013
Structure-activity relationship of imidazopyridinium analogues as antagonists of neuropeptide s receptor. Journal of medicinal chemistry\| PubMed ID: 24171469	2013
The role of the neurokinin-1 receptor in stress-induced reinstatement of alcohol and cocaine seeking. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology\| PubMed ID: 24173499	2014
Gender differences in neural-behavioral response to self-observation during a novel fMRI social stress task. Neuropsychologia\| PubMed ID: 24316200	2014
[Opioid dependence: New national guidelines must allow maintenance treatment]. Lakartidningen\| PubMed ID: 24340431	2013
Restraint stress alters nociceptin/orphanin FQ and CRF systems in the rat central amygdala: significance for anxiety-like behaviors. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 24403138	2014
Acamprosate: an alcoholism treatment that may not be what we thought. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology\| PubMed ID: 24518272	2014
FKBP5 moderates alcohol withdrawal severity: human genetic association and functional validation in knockout mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology\| PubMed ID: 24603855	2014
Alcohol-preferring rats show decreased corticotropin-releasing hormone-2 receptor expression and differences in HPA activation compared to alcohol-nonpreferring rats. Alcoholism, clinical and experimental research\| PubMed ID: 24611993	2014
Stress and alcohol interactions: animal studies and clinical significance. Trends in neurosciences\| PubMed ID: 24636458	2014
microRNA-206 in rat medial prefrontal cortex regulates BDNF expression and alcohol drinking. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 24672003	2014
Cerebrospinal fluid monocyte chemoattractant protein-1 in alcoholics: support for a neuroinflammatory model of chronic alcoholism. Alcoholism, clinical and experimental research\| PubMed ID: 24689518	2014
Kappa-opioid receptor antagonism: a mechanism for treatment of relief drinking? Biological psychiatry\| PubMed ID: 24780009	2014
Methods for inducing alcohol craving in individuals with co-morbid alcohol dependence and posttraumatic stress disorder: behavioral and physiological outcomes. Addiction biology\| PubMed ID: 24806358	2015
Chronic treatment with novel brain-penetrating selective NOP receptor agonist MT-7716 reduces alcohol drinking and seeking in the rat. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology\| PubMed ID: 24863033	2014
The neurokinin-1 receptor antagonist aprepitant in co-morbid alcohol dependence and posttraumatic stress disorder: a human experimental study. Psychopharmacology\| PubMed ID: 25030801	2015
Polymorphism in the corticotropin-releasing factor receptor 1 (CRF1-R) gene plays a role in shaping the high anxious phenotype of Marchigian Sardinian alcohol-preferring (msP) rats. Psychopharmacology\| PubMed ID: 25260340	2015
PPARγ activation attenuates opioid consumption and modulates mesolimbic dopamine transmission. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology\| PubMed ID: 25311134	2015
Reduced anterior insula, enlarged amygdala in alcoholism and associated depleted von Economo neurons. Brain : a journal of neurology\| PubMed ID: 25367022	2015
Hypocretin receptor 2 antagonism dose-dependently reduces escalated heroin self-administration in rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology\| PubMed ID: 25367502	2015
Daniel W. Hommer. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology\| PubMed ID: 25381706	2014
The corticotropin releasing hormone-1 (CRH1) receptor antagonist pexacerfont in alcohol dependence: a randomized controlled experimental medicine study. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology\| PubMed ID: 25409596	2015
A pharmacogenetic determinant of mu-opioid receptor antagonist effects on alcohol reward and consumption: evidence from humanized mice. Biological psychiatry\| PubMed ID: 25442002	2015
Effects of naltrexone on neural and subjective response to alcohol in treatment-seeking alcohol-dependent patients. Alcoholism, clinical and experimental research\| PubMed ID: 25581657	2014
PPARc activation attenuates opioid consumption and modulates mesolimbic dopamine transmission. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology\| PubMed ID: 25668637	2015
The role of expectation in the therapeutic outcomes of alcohol and drug addiction treatments. Alcohol and alcoholism (Oxford, Oxfordshire)\| PubMed ID: 25761920	2015
DNA methylation in the medial prefrontal cortex regulates alcohol-induced behavior and plasticity. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 25878287	2015
Receptor Reserve Moderates Mesolimbic Responses to Opioids in a Humanized Mouse Model of the OPRM1 A118G Polymorphism. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology\| PubMed ID: 25881115	2015
Circumspectives: The Replacements. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology\| PubMed ID: 26068571	2015
Effects of Varenicline on Neural Correlates of Alcohol Salience in Heavy Drinkers. The international journal of neuropsychopharmacology\| PubMed ID: 26209857	2015
Neurokinin 1 receptor blockade in the medial amygdala attenuates alcohol drinking in rats with innate anxiety but not in Wistar rats. British journal of pharmacology\| PubMed ID: 26275374	2015
Glutamatergic transmission in the central nucleus of the amygdala is selectively altered in Marchigian Sardinian alcohol-preferring rats: Alcohol and CRF effects. Neuropharmacology\| PubMed ID: 26519902	2016
Circumspectives: Cannabis and Psychiatric Illness: Blunt Thoughts. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology\| PubMed ID: 26555278	2016
What the alcohol doctor ordered from the neuroscientist: Theragnostic biomarkers for personalized treatments. Progress in brain research\| PubMed ID: 26822368	2016
mRNA GPR162 changes are associated with decreased food intake in rat, and its human genetic variants with impairments in glucose homeostasis in two Swedish cohorts. Gene\| PubMed ID: 26827797	2016
Tunable Diffractive Optical Elements Based on Shape-Memory Polymers Fabricated via Hot Embossing. ACS applied materials & interfaces\| PubMed ID: 26998646	2016
The melanin-concentrating hormone-1 receptor modulates alcohol-induced reward and DARPP-32 phosphorylation. Psychopharmacology\| PubMed ID: 27044354	2016
The Effect of Varenicline on the Neural Processing of Fearful Faces and the Subjective Effects of Alcohol in Heavy Drinkers. Alcoholism, clinical and experimental research\| PubMed ID: 27062270	2016
The CRF1 Antagonist Verucerfont in Anxious Alcohol-Dependent Women: Translation of Neuroendocrine, But not of Anti-Craving Effects. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology\| PubMed ID: 27109623	2016
Characterization of comorbid PTSD in treatment-seeking alcohol dependent inpatients: Severity and personality trait differences. Drug and alcohol dependence\| PubMed ID: 27114205	2016
The Need for Treatment Responsive Translational Biomarkers in Alcoholism Research. Current topics in behavioral neurosciences\| PubMed ID: 27240677	2016
Proinflammatory signaling regulates voluntary alcohol intake and stress-induced consumption after exposure to social defeat stress in mice. Addiction biology\| PubMed ID: 27273552	2016
Time to connect: bringing social context into addiction neuroscience. Nature reviews. Neuroscience\| PubMed ID: 27277868	2016
The mGluR2 Positive Allosteric Modulator, AZD8529, and Cue-Induced Relapse to Alcohol Seeking in Rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology\| PubMed ID: 27339394	2016
OPRM1 genotype interacts with serotonin system dysfunction to predict alcohol-heightened aggression in primates. Addiction biology\| PubMed ID: 27484010	2016
The nociceptin/orphanin FQ receptor agonist SR-8993 as a candidate therapeutic for alcohol use disorders: validation in rat models. Psychopharmacology\| PubMed ID: 27515665	2016
Melanin-Concentrating Hormone and Its MCH-1 Receptor: Relationship Between Effects on Alcohol and Caloric Intake. Alcoholism, clinical and experimental research\| PubMed ID: 27579857	2016
Effect of the CRF1-receptor antagonist pexacerfont on stress-induced eating and food craving. Psychopharmacology\| PubMed ID: 27595147	2016
Erratum to: The melanin-concentrating hormone-1 receptor modulates alcohol-induced reward and DARPP-32 phosphorylation. Psychopharmacology\| PubMed ID: 27650828	2016
FAAH Gene Variation Moderates Stress Response and Symptom Severity in Patients with Posttraumatic Stress Disorder and Comorbid Alcohol Dependence. Alcoholism, clinical and experimental research\| PubMed ID: 27716956	2016
Genetic Deletion of Neuronal PPARγ Enhances the Emotional Response to Acute Stress and Exacerbates Anxiety: An Effect Reversed by Rescue of Amygdala PPARγ Function. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 27810934	2016
Concurrent Treatment of PTSD and Substance Use Disorders Using Prolonged Exposure (COPE): A Pilot Study in Alcohol-dependent Women. Journal of addiction medicine\| PubMed ID: 28079572	2017
Addiction research and theory: a commentary on the Surgeon General's Report on alcohol, drugs, and health. Addiction biology\| PubMed ID: 28224686	2018
The GABA Positive Allosteric Modulator ADX71441 Attenuates Alcohol Self-Administration and Relapse to Alcohol Seeking in Rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology\| PubMed ID: 28294133	2017
mTORC and ProSAPiP1: How Alcohol Changes Synapses of Reward Circuitry. Neuron\| PubMed ID: 28957677	2017
Substance P and the Neurokinin-1 Receptor: The New CRF. International review of neurobiology\| PubMed ID: 29056150	2017
Early rearing history influences oxytocin receptor epigenetic regulation in rhesus macaques. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 29078292	2017
Deep TMS of the insula using the H-coil modulates dopamine release: a crossover [C] PHNO-PET pilot trial in healthy humans. Brain imaging and behavior\| PubMed ID: 29170944	2018
A cannabinoid receptor antagonist attenuates ghrelin-induced activation of the mesolimbic dopamine system in mice. Physiology & behavior\| PubMed ID: 29221808	2018
Insula Sensitivity to Unfairness in Alcohol Use Disorder. Alcohol and alcoholism (Oxford, Oxfordshire)\| PubMed ID: 29309499	2018
Neural responses to cues paired with methamphetamine in healthy volunteers. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology\| PubMed ID: 29463908	2018
Several behavioral traits relevant for alcoholism are controlled by ɣ2 subunit containing GABA receptors on dopamine neurons in mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology\| PubMed ID: 29463910	2018
Preclinical evaluation of the kappa-opioid receptor antagonist CERC-501 as a candidate therapeutic for alcohol use disorders. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology\| PubMed ID: 29463912	2018
Genetic Association and Expression Analyses of the Phosphatidylinositol-4-Phosphate 5-Kinase (PIP5K1C) Gene in Alcohol Use Disorder-Relevance for Pain Signaling and Alcohol Use. Alcoholism, clinical and experimental research\| PubMed ID: 29667742	2018
The salience of self, not social pain, is encoded by dorsal anterior cingulate and insula. Scientific reports\| PubMed ID: 29670166	2018
The novel ghrelin receptor inverse agonist PF-5190457 administered with alcohol: preclinical safety experiments and a phase 1b human laboratory study. Molecular psychiatry\| PubMed ID: 29728704	2018
A molecular mechanism for choosing alcohol over an alternative reward. Science (New York, N.Y.)\| PubMed ID: 29930131	2018
Putting a good face on touch: Facial expression reflects the affective valence of caress-like touch across modalities. Biological psychology\| PubMed ID: 30003943	2018
Protective effects of elevated anandamide on stress and fear-related behaviors: translational evidence from humans and mice. Molecular psychiatry\| PubMed ID: 30120421	2018
Neural Correlates of Compulsive Alcohol Seeking in Heavy Drinkers. Biological psychiatry. Cognitive neuroscience and neuroimaging\| PubMed ID: 30143454	2018
Science-Based Actions Can Help Address the Opioid Crisis. Trends in pharmacological sciences\| PubMed ID: 30343726	2018
Lack of Target Engagement Following Low-Frequency Deep Transcranial Magnetic Stimulation of the Anterior Insula. Neuromodulation : journal of the International Neuromodulation Society\| PubMed ID: 30370983	2018
Striatal dopamine deficits predict reductions in striatal functional connectivity in major depression: a concurrent C-raclopride positron emission tomography and functional magnetic resonanc... Translational psychiatry\| PubMed ID: 30504860	2018
Distinction of self-produced touch and social touch at cortical and spinal cord levels. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 30670645	2019