Edith M. Janssen

Division of Immunobiology, Cincinnati Children's Hospital Medical Center and University of Cincinnati College of Medicine

Affiliated withCincinnati Children's Hospital Medical Center and University of Cincinnati College of Medicine

Research Area

Medicine

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 38	2015

Other Publications

Article	Year
Immunomodulatory effects of antigen-pulsed macrophages in a murine model of allergic asthma. American journal of respiratory cell and molecular biology\| PubMed ID: 12151319	2002
CD4+ T cells are required for secondary expansion and memory in CD8+ T lymphocytes. Nature\| PubMed ID: 12594515	2003
Upregulation of costimulatory molecules induced by lipopolysaccharide and double-stranded RNA occurs by Trif-dependent and Trif-independent pathways. Nature immunology\| PubMed ID: 14625548	2003
CD4+ T-cell help controls CD8+ T-cell memory via TRAIL-mediated activation-induced cell death. Nature\| PubMed ID: 15744305	2005
Protein kinase C-theta is an early survival factor required for differentiation of effector CD8+ T cells. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 16210616	2005
Anti-T-cell Ig and mucin domain-containing protein 1 antibody decreases TH2 airway inflammation in a mouse model of asthma. The Journal of allergy and clinical immunology\| PubMed ID: 16337469	2005
The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9. Nature immunology\| PubMed ID: 16415873	2006
IL-2 gets with the program. Nature immunology\| PubMed ID: 16855604	2006
Dendritic cell programming by cytomegalovirus stunts naive T cell responses via the PD-L1/PD-1 pathway. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 18354207	2008
LXR signaling couples sterol metabolism to proliferation in the acquired immune response. Cell\| PubMed ID: 18614014	2008
CD4 cell-secreted, posttranslationally modified cytokine GIF suppresses Th2 responses by inhibiting the initiation of IL-4 production. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19036925	2008
Distinct roles of cytolytic effector molecules for antigen-restricted killing by CTL in vivo. Immunology and cell biology\| PubMed ID: 20309009	2010
Immunosuppression: learning from the masters. Expert review of clinical immunology\| PubMed ID: 20477014	2007
Cutting edge: merocytic dendritic cells break T cell tolerance to beta cell antigens in nonobese diabetic mouse diabetes. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 20644171	2010
Prolonged antigen storage endows merocytic dendritic cells with enhanced capacity to prime anti-tumor responses in tumor-bearing mice. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 20720209	2010
Interleukin-2 rescues helpless effector CD8+ T cells by diminishing the susceptibility to TRAIL mediated death. Immunology letters\| PubMed ID: 21621553	2011
Breaking T cell tolerance to beta cell antigens by merocytic dendritic cells. Cellular and molecular life sciences : CMLS\| PubMed ID: 21626409	2011
Immune adjuvant efficacy of CpG oligonucleotide in cancer treatment is founded specifically upon TLR9 function in plasmacytoid dendritic cells. Cancer research\| PubMed ID: 21788345	2011
Nab2 regulates secondary CD8+ T-cell responses through control of TRAIL expression. Blood\| PubMed ID: 22128144	2012
Cross-presentation of cell-associated antigens by mouse splenic dendritic cell populations. Frontiers in immunology\| PubMed ID: 22566924	2012
Melanoma-infiltrating dendritic cells: Limitations and opportunities of mouse models. Oncoimmunology\| PubMed ID: 23264904	2012
Respond to "No antigen-presentation defect in Unc93b1(3d/3d) (3d) mice". Nature immunology\| PubMed ID: 24145779	2013
Harnessing dendritic cells for tumor antigen presentation. Cancers\| PubMed ID: 24212804	2011
DNA methylation dynamics during ex vivo differentiation and maturation of human dendritic cells. Epigenetics & chromatin\| PubMed ID: 25161698	2014
STING-mediated DNA sensing promotes antitumor and autoimmune responses to dying cells. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 25385820	2014
Quantitating MHC class II trafficking in primary dendritic cells using imaging flow cytometry. Journal of immunological methods\| PubMed ID: 25967952	2015
Loss of Phagocytic and Antigen Cross-Presenting Capacity in Aging Dendritic Cells Is Associated with Mitochondrial Dysfunction. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 26246142	2015
Ablation of CD8α(+) dendritic cell mediated cross-presentation does not impact atherosclerosis in hyperlipidemic mice. Scientific reports\| PubMed ID: 26486587	2015