a-novel-strategy-combining-array-cgh-whole-exome-sequencing-utero

A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and <em>In Utero</em> Electroporation in Rodents to Identify Causative Genes for Brain Malformations

Birth defects that involve the cerebral cortex &#8212; also known as malformations of cortical development (MCD) &#8212; are important causes of ...

INSERM INMED

Aix-Marseille University

Plateforme Biologie Moléculaire et Cellulaire INMED

Transcription is the initial and generally the most sensitive step to cellular needs and environmental cues. Thus, it serves as a major mechanism controlling gene expression. Using reverse-transcription quantitative polymerase chain reaction technology (RT-qPCR), we will present how to quantify the transcriptional expression of NMDARs subunits during brain development and in both healthy and pathological conditions.

Emilie Pallesi-Pocachard

Biography

JoVE Journal Publications

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