Wei-Li Wu

Wei-Li Wu

Division of Biology and Biological Engineering, California Institute of Technology

Affiliated withCalifornia Institute of TechnologyNational Cheng Kung University

Research Area

Biography

Dr. Wei-Li Wu is an assistant professor in the Department of Physiology at the College of Medicine, National Cheng Kung University. Dr. Wu received his M.S. degree in marine biology with Dr. Hin-Kiu Mok and Dr. Chi-Ying Lee as advisors at National Sun Yat-sen University. Dr. Wu's master's study investigated neurotransmission during aggressive behavior using a fighting fish model. Then Dr. Wu received his Ph.D. degree in neuroscience with Dr. Chih-Cheng Chen as advisor at the Academia Sinica. In the Ph.D. training, he profiled the alternations of emotion-related behaviors in a mouse model with sensory deficits. After completing the doctoral degree, Dr. Wu joined the late Prof. Paul Patterson laboratory at Caltech as a postdoctoral scholar in neuroimmunology from 2012 to 2014. In Patterson laboratory, Dr. Wu focused on the gene x environment interactions in a preclinical mouse model of autism spectrum disorder (ASD) and schizophrenia, maternal immune activation. In 2014, Dr. Wu joined Prof. Sarkis Mazmanian laboratory at Caltech to carry on his works from the Patterson lab and to explore a brand-new direction: understanding how gut microbiota mediate mental homeostasis and disease. In Mazmanian laboratory, Dr. Wu interrogated the microbiota-based neural circuits underlying the social behavior using germ-free and antibiotics-treated mice, the mice deprived of the gut microbiota. In 2018, Dr. Wu set up his laboratory at National Cheng Kung University and continuously worked to unravel the neural mechanism by which gut microbiota impact brain circuits and host behaviors.

JoVE Journal Publications

ArticleTotal : 2
Year
Induction of Maternal Immune Activation in Mice at Mid-gestation Stage with Viral Mimic Poly(I:C)
Publication title

Cited by 25

2016
2022

Other Publications

Article
Year
Apoptotic effect of As2S2 on K562 cells and its mechanism.

Acta pharmacologica Sinica| PubMed ID: 12421474

2002
[New Retinoid SX-116 Induces Apoptosis of Acute Promyelocytic Leukemia Cell Line NB4]

Zhongguo shi yan xue ye xue za zhi / Zhongguo bing li sheng li xue hui = Journal of experimental hematology / Chinese Association of Pathophysiology| PubMed ID: 12578641

2001
[Preliminary study on the molecular mechanism of K562 cell apoptosis induced by As2S2].

Zhonghua zhong liu za zhi [Chinese journal of oncology]| PubMed ID: 12839680

2003
[Studies on the dynamics of biological characteristics of CD133+ cells from human umbilical cord blood during short-term culture].

Zhongguo shi yan xue ye xue za zhi / Zhongguo bing li sheng li xue hui = Journal of experimental hematology / Chinese Association of Pathophysiology| PubMed ID: 14706136

2003
[Synergism of As2S2 and STI 571 in inducing apoptosis of K562 cells].

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi| PubMed ID: 14720443

2003
[Effect of TGF-beta1 on biological characteristics of umbilical cord blood hematopoietic progenitor cells during ex-vivo expansion].

Zhongguo shi yan xue ye xue za zhi / Zhongguo bing li sheng li xue hui = Journal of experimental hematology / Chinese Association of Pathophysiology| PubMed ID: 14989763

2004
[The reliability and validity of adult attachment scale (AAS-1996 revised edition): a report on its application in China].

Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition| PubMed ID: 15291121

2004
[Relationship between the adult attachment styles of social anxiety disorder (SAD) and its cognitive mode and behavior mode].

Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition| PubMed ID: 15807286

2005
2005
2006
2007
2007
2008
2007
2008
An amperometric horseradish peroxidase inhibition biosensor for the determination of phenylhydrazine.

Analytical sciences : the international journal of the Japan Society for Analytical Chemistry| PubMed ID: 18614832

2008
[The influence of self-improving based group psychotherapy in defense mechanisms for the clients with social anxiety disorder].

Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition| PubMed ID: 19253851

2008
2009
Voltammetric Behavior of o-Nitrophenol and Damage to DNA.

International journal of molecular sciences| PubMed ID: 19325751

2008
2009
2009
2009
[Synergistic effects of proteasome inhibitor and histone deacetylase inhibitor on apoptosis and aggresome formation in T lymphoma cells].

Zhongguo shi yan xue ye xue za zhi / Zhongguo bing li sheng li xue hui = Journal of experimental hematology / Chinese Association of Pathophysiology| PubMed ID: 19840453

2009
Histone H3 lysine 36 methyltransferase Hypb/Setd2 is required for embryonic vascular remodeling.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 20133625

2010
2010
[The effects of cardiac pacing with multisite combination on myocardial mechanics and cardiac work in dogs].

Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology| PubMed ID: 21166231

2003
2011
2011
[Mammary serine proteinase inhibitor subcellular expression in oral squamous cell carcinoma and its clinical significance].

Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology| PubMed ID: 22169751

2011
Targeting ASIC3 for pain, anxiety, and insulin resistance.

Pharmacology & therapeutics| PubMed ID: 22233754

2012
2012
2012
2012
2014
2016
2014
2015
2015
2015
Bilaterality weighs more than unilateral multifocality in predicting prognosis in papillary thyroid cancer.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine| PubMed ID: 26743781

2016
2016
2018
2019
2022
2022