Maarten Merkx

Laboratory of Chemical Biology, Institute of Complex Molecular Systems (ICMS)

Affiliated withInstitute of Complex Molecular Systems (ICMS)Eindhoven University of Technology

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 8	2016

Other Publications

Article	Year
Cover Picture. Angewandte Chemie (International ed. in English)\| PubMed ID: 11500870	2001
Dioxygen Activation and Methane Hydroxylation by Soluble Methane Monooxygenase: A Tale of Two Irons and Three Proteins A list of abbreviations can be found in Section 7. Angewandte Chemie (International ed. in English)\| PubMed ID: 11500872	2001
Why OrfY? Characterization of MMOD, a long overlooked component of the soluble methane monooxygenase from Methylococcus capsulatus (Bath). The Journal of biological chemistry\| PubMed ID: 11709550	2002
Determination by X-ray absorption spectroscopy of the Fe-Fe separation in the oxidized form of the hydroxylase of methane monooxygenase alone and in the presence of MMOD. Inorganic chemistry\| PubMed ID: 15257585	2004
Copper-dependent protein-protein interactions studied by yeast two-hybrid analysis. Biochemical and biophysical research communications\| PubMed ID: 15381069	2004
Preparation and X-ray structures of metal-free, dicobalt and dimanganese forms of soluble methane monooxygenase hydroxylase from Methylococcus capsulatus (Bath). Biochemistry\| PubMed ID: 15610020	2004
Successful recombinant production of Allochromatium vinosum cytochrome c' requires coexpression of cmm genes in heme-rich Escherichia coli JCB712. Biochemical and biophysical research communications\| PubMed ID: 15649399	2005
Electrochemical reduction of NO by hemin adsorbed at pyrolitic graphite. Journal of the American Chemical Society\| PubMed ID: 15898809	2005
Multivalent peptide and protein dendrimers using native chemical ligation. Angewandte Chemie (International ed. in English)\| PubMed ID: 16007714	2005
Heme release in myoglobin-DDAB films and its role in electrochemical NO reduction. Journal of the American Chemical Society\| PubMed ID: 16287313	2005
Fluorescently labeled collagen binding proteins allow specific visualization of collagen in tissues and live cell culture. Analytical biochemistry\| PubMed ID: 16476406	2006
Ratiometric fluorescent sensor proteins with subnanomolar affinity for Zn(II) based on copper chaperone domains. Journal of the American Chemical Society\| PubMed ID: 16910670	2006
Quantitative understanding of the energy transfer between fluorescent proteins connected via flexible peptide linkers. Biochemistry\| PubMed ID: 17073440	2006
Electron transfer and ligand binding to cytochrome c' immobilized on self-assembled monolayers. Langmuir : the ACS journal of surfaces and colloids\| PubMed ID: 17209627	2007
Allocation of substance use disorder patients to appropriate levels of care: feasibility of matching guidelines in routine practice in Dutch treatment centres. Addiction (Abingdon, England)\| PubMed ID: 17298655	2007
Protein-liposome conjugates using cysteine-lipids and native chemical ligation. Bioconjugate chemistry\| PubMed ID: 17315942	2007
Reorganization of immobilized horse and yeast cytochrome c induced by pH changes or nitric oxide binding. Langmuir : the ACS journal of surfaces and colloids\| PubMed ID: 17319704	2007
Variation of linker length in ratiometric fluorescent sensor proteins allows rational tuning of Zn(II) affinity in the picomolar to femtomolar range. Journal of the American Chemical Society\| PubMed ID: 17335212	2007
Evidence for heme release in layer-by-layer assemblies of myoglobin and polystyrenesulfonate on pyrolitic graphite. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry\| PubMed ID: 17410384	2007
Enhanced sensitivity of FRET-based protease sensors by redesign of the GFP dimerization interface. Chembiochem : a European journal of chemical biology\| PubMed ID: 17525917	2007
Ligand-induced monomerization of Allochromatium vinosum cytochrome c' studied using native mass spectrometry and fluorescence resonance energy transfer. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry\| PubMed ID: 17546467	2007
High resolution imaging of collagen organisation and synthesis using a versatile collagen specific probe. Journal of structural biology\| PubMed ID: 17572104	2007
Human copper transporter 2 is localized in late endosomes and lysosomes and facilitates cellular copper uptake. The Biochemical journal\| PubMed ID: 17617060	2007
Imaging collagen in intact viable healthy and atherosclerotic arteries using fluorescently labeled CNA35 and two-photon laser scanning microscopy. Molecular imaging\| PubMed ID: 17711780	2007
Branched KLVFF tetramers strongly potentiate inhibition of beta-amyloid aggregation. Chembiochem : a European journal of chemical biology\| PubMed ID: 17763487	2007
Site-specific protein and peptide immobilization on a biosensor surface by pulsed native chemical ligation. Chembiochem : a European journal of chemical biology\| PubMed ID: 17763488	2007
Ratiometric detection of Zn(II) using chelating fluorescent protein chimeras. Journal of molecular biology\| PubMed ID: 17936298	2007
Mapping preferred sites for fluorescent labeling by combining fluorescence and MS analysis of tryptic CNA35 protein digests. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences\| PubMed ID: 18272440	2008
His-tags as Zn(II) binding motifs in a protein-based fluorescent sensor. Protein engineering, design & selection : PEDS\| PubMed ID: 18502789	2008
Biomechanical properties of abdominal aortic aneurysms assessed by simultaneously measured pressure and volume changes in humans. Journal of vascular surgery\| PubMed ID: 18771885	2008
One-step refolding and purification of disulfide-containing proteins with a C-terminal MESNA thioester. BMC biotechnology\| PubMed ID: 18828922	2008
Two-photon microscopy on vital carotid arteries: imaging the relationship between collagen and inflammatory cells in atherosclerotic plaques. Journal of biomedical optics\| PubMed ID: 19021350	2008
Multivalent choline dendrimers as potent inhibitors of pneumococcal cell-wall hydrolysis. Angewandte Chemie (International ed. in English)\| PubMed ID: 19115336	2009
Efficient and chemoselective surface immobilization of proteins by using aniline-catalyzed oxime chemistry. Chembiochem : a European journal of chemical biology\| PubMed ID: 19241407	2009
Collagen targeting using protein-functionalized micelles: the strength of multiple weak interactions. Journal of the American Chemical Society\| PubMed ID: 19469576	2009
Feasibility and validity of low-budget telephonic follow-up interviews in routine outcome monitoring of substance abuse treatment. Addiction (Abingdon, England)\| PubMed ID: 19563559	2009
Noncovalent synthesis of protein dendrimers. Chemistry (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 19609988	2009
Efficient, chemoselective synthesis of immunomicelles using single-domain antibodies with a C-terminal thioester. BMC biotechnology\| PubMed ID: 19619333	2009
High-affinity peptide-based collagen targeting using synthetic phage mimics: from phage display to dendrimer display. Journal of the American Chemical Society\| PubMed ID: 19642697	2009
Genetically encoded FRET sensors to monitor intracellular Zn2+ homeostasis. Nature methods\| PubMed ID: 19718032	2009
Exchange kinetics of protein-functionalized micelles and liposomes studied by Förster resonance energy transfer. Bioconjugate chemistry\| PubMed ID: 20397687	2010
Protease-activatable collagen targeting based on protein cyclization. Chembiochem : a European journal of chemical biology\| PubMed ID: 20589824	2010
Collagen targeting using multivalent protein-functionalized dendrimers. Bioorganic & medicinal chemistry\| PubMed ID: 20724168	2011
Antibody detection by using a FRET-based protein conformational switch. Chembiochem : a European journal of chemical biology\| PubMed ID: 20928879	2010
The binding of CNA35 contrast agents to collagen fibrils. Chemical communications (Cambridge, England)\| PubMed ID: 21088778	2011
Guidelines for allocating outpatient alcohol abusers to levels of care: Predictive validity. Addictive behaviors\| PubMed ID: 21236585	2011
Dendrimer display of tumor-homing peptides. Bioconjugate chemistry\| PubMed ID: 21261269	2011
Engineering protein switches: sensors, regulators, and spare parts for biology and biotechnology. Chembiochem : a European journal of chemical biology\| PubMed ID: 21271630	2011
From phage display to dendrimer display: insights into multivalent binding. Journal of the American Chemical Society\| PubMed ID: 21473586	2011
Choline dendrimers as generic scaffolds for the non-covalent synthesis of multivalent protein assemblies. Chemical communications (Cambridge, England)\| PubMed ID: 21512694	2011
NMR characterization of a Cu(I)-bound peptide model of copper metallochaperones: insights on the role of methionine. Chemical communications (Cambridge, England)\| PubMed ID: 21552638	2011
Chemoselective protein and peptide immobilization on biosensor surfaces. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 21674345	2011
Semi-synthesis of a protease-activatable collagen targeting probe. Chemical communications (Cambridge, England)\| PubMed ID: 21691626	2011
Reengineering of a fluorescent zinc sensor protein yields the first genetically encoded cadmium probe. Chemical communications (Cambridge, England)\| PubMed ID: 21986860	2011
In vivo characterization of a new abdominal aortic aneurysm mouse model with conventional and molecular magnetic resonance imaging. Journal of the American College of Cardiology\| PubMed ID: 22133853	2011
Colorful calcium sensors. Chembiochem : a European journal of chemical biology\| PubMed ID: 22234942	2012
Calculation of transition dipole moment in fluorescent proteins--towards efficient energy transfer. Physical chemistry chemical physics : PCCP\| PubMed ID: 22331099	2012
Accuracy and precision of vessel area assessment: manual versus automatic lumen delineation based on full-width at half-maximum. Journal of magnetic resonance imaging : JMRI\| PubMed ID: 22826150	2012
Monitoring bile acid transport in single living cells using a genetically encoded Förster resonance energy transfer sensor. Hepatology (Baltimore, Md.)\| PubMed ID: 22899095	2013
Tuning the metal binding site specificity of a fluorescent sensor protein: from copper to zinc and back. Dalton transactions (Cambridge, England : 2003)\| PubMed ID: 23076326	2013
Predictive validity of treatment allocation guidelines on drinking outcome in alcohol-dependent patients. Addictive behaviors\| PubMed ID: 23254220	2013
Supramolecular control of enzyme activity through cucurbit[8]uril-mediated dimerization. Angewandte Chemie (International ed. in English)\| PubMed ID: 23355250	2013
The benefit of non contrast-enhanced magnetic resonance angiography for predicting vascular access surgery outcome: a computer model perspective. PloS one\| PubMed ID: 23390490	2013
Non contrast-enhanced MRA versus ultrasound blood vessel assessment to determine the choice of hemodialysis vascular access. The journal of vascular access\| PubMed ID: 23817956	2013
Switchable reporter enzymes based on mutually exclusive domain interactions allow antibody detection directly in solution. ACS chemical biology\| PubMed ID: 23941162	2013
Robust red FRET sensors using self-associating fluorescent domains. ACS chemical biology\| PubMed ID: 23962156	2013
Rational design of FRET sensor proteins based on mutually exclusive domain interactions. Biochemical Society transactions\| PubMed ID: 24059509	2013
No washing, less waiting: engineering biomolecular reporters for single-step antibody detection in solution. Organic & biomolecular chemistry\| PubMed ID: 24091607	2013
MagFRET: the first genetically encoded fluorescent Mg2+ sensor. PloS one\| PubMed ID: 24312622	2013
Dynamic imaging of cytosolic zinc in Arabidopsis roots combining FRET sensors and RootChip technology. The New phytologist\| PubMed ID: 24372442	2014
Engineering genetically encoded FRET sensors. Sensors (Basel, Switzerland)\| PubMed ID: 24991940	2014
Mitochondrial and ER-targeted eCALWY probes reveal high levels of free Zn2+. ACS chemical biology\| PubMed ID: 25011072	2014
Genetically-encoded FRET-based sensors for monitoring Zn(2+) in living cells. Metallomics : integrated biometal science\| PubMed ID: 25156481	2015
DNA-directed control of enzyme-inhibitor complex formation: a modular approach to reversibly switch enzyme activity. ACS synthetic biology\| PubMed ID: 25216042	2015
Quantifying stickiness: thermodynamic characterization of intramolecular domain interactions to guide the design of förster resonance energy transfer sensors. Biochemistry\| PubMed ID: 25216081	2014
Treatment outcome of alcohol use disorder outpatients with or without medically assisted detoxification. Journal of studies on alcohol and drugs\| PubMed ID: 25343657	2014
Colorful protein-based fluorescent probes for collagen imaging. PloS one\| PubMed ID: 25490719	2014
Antibody activation using DNA-based logic gates. Angewandte Chemie (International ed. in English)\| PubMed ID: 25573528	2015
Efficient Synthesis of Peptide and Protein Functionalized Pyrrole-Imidazole Polyamides Using Native Chemical Ligation. International journal of molecular sciences\| PubMed ID: 26053396	2015
eZinCh-2: A Versatile, Genetically Encoded FRET Sensor for Cytosolic and Intraorganelle Zn(2+) Imaging. ACS chemical biology\| PubMed ID: 26151333	2015
Inhibition of human copper trafficking by a small molecule significantly attenuates cancer cell proliferation. Nature chemistry\| PubMed ID: 26587712	2015