Youngjoo Kwon

Department of Medical Oncology, Women's Cancer Program

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 38	2010

Other Publications

Article	Year
Induced formation of a DNA bulge structure by a molecular wedge ligand-postactivated neocarzinostatin chromophore. Biochemistry\| PubMed ID: 11955061	2002
New complex of post-activated neocarzinostatin chromophore with DNA: bulge DNA binding from the minor groove. Biochemistry\| PubMed ID: 12564921	2003
A wrench-shaped synthetic molecule that modulates a transcription factor-coactivator interaction. Journal of the American Chemical Society\| PubMed ID: 15025473	2004
Inhibition of colonic aberrant crypt foci by curcumin in rats is affected by age. Nutrition and cancer\| PubMed ID: 15203376	2004
Small molecule transcription factor mimic. Journal of the American Chemical Society\| PubMed ID: 15584709	2004
Study on the synthesis and cytotoxicity of new quinophenoxazine derivatives. Chemical & pharmaceutical bulletin\| PubMed ID: 16462076	2006
Anthocyanin-rich extracts inhibit multiple biomarkers of colon cancer in rats. Nutrition and cancer\| PubMed ID: 16800776	2006
Effect of azoxymethane and curcumin on transcriptional levels of cyclooxygenase-1 and -2 during initiation of colon carcinogenesis. Scandinavian journal of gastroenterology\| PubMed ID: 17190766	2007
Synthesis of new xanthone analogues and their biological activity test--cytotoxicity, topoisomerase II inhibition, and DNA cross-linking study. Bioorganic & medicinal chemistry letters\| PubMed ID: 17194586	2007
Polyproline-rod approach to isolating protein targets of bioactive small molecules: isolation of a new target of indomethacin. Journal of the American Chemical Society\| PubMed ID: 17243824	2007
P-glycoprotein inhibitory activity of two phenolic compounds, (-)-syringaresinol and tricin from Sasa borealis. Chemistry & biodiversity\| PubMed ID: 17256728	2007
Modulation of P-glycoprotein-mediated resistance by kaempferol derivatives isolated from Zingiber zerumbet. Phytotherapy research : PTR\| PubMed ID: 17335117	2007
Design, docking, and synthesis of novel indeno[1,2-c]isoquinolines for the development of antitumor agents as topoisomerase I inhibitors. Bioorganic & medicinal chemistry letters\| PubMed ID: 17498951	2007
Convenient synthesis of indeno[1,2-c]isoquinolines as constrained forms of 3-arylisoquinolines and docking study of a topoisomerase I inhibitor into DNA-topoisomerase I complex. Bioorganic & medicinal chemistry letters\| PubMed ID: 17827007	2007
Aging alters acute apoptotic response to azoxymethane in the colon of rats. Experimental gerontology\| PubMed ID: 17961945	2007
First synthesis of 4'-selenonucleosides showing unusual Southern conformation. Organic letters\| PubMed ID: 18088134	2008
New insight for fluoroquinophenoxazine derivatives as possibly new potent topoisomerase I inhibitor. Bioorganic & medicinal chemistry letters\| PubMed ID: 18178085	2008
Ovarian normal and tumor-associated fibroblasts retain in vivo stromal characteristics in a 3-D matrix-dependent manner. Gynecologic oncology\| PubMed ID: 18448156	2008
2,2-dimethyl-2H-pyran-derived alkaloids I. Practical synthesis of acronycine and benzo[b]acronycine and their biological properties. Archives of pharmacal research\| PubMed ID: 18806949	2008
A rapid and sensitive screening system for human type I collagen with the aim of discovering potent anti-aging or anti-fibrotic compounds. Molecules and cells\| PubMed ID: 18810249	2008
Age-related differential responses to curcumin-induced apoptosis during the initiation of colon cancer in rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association\| PubMed ID: 19095035	2009
Wrenchnolol derivative optimized for gene activation in cells. Journal of the American Chemical Society\| PubMed ID: 19290630	2009
Molecular design, synthesis and docking study of benz[b]oxepines and 12-oxobenzo[c]phenanthridinones as topoisomerase 1 inhibitors. Bioorganic & medicinal chemistry letters\| PubMed ID: 19345580	2009
Identification of 3-acetyl-2-aminoquinolin-4-one as a novel, nonpeptidic scaffold for specific calpain inhibitory activity. Journal of medicinal chemistry\| PubMed ID: 19419206	2009
A concise synthesis of licochalcone E and its regio-isomer, licochalcone F. Chemical & pharmaceutical bulletin\| PubMed ID: 19483343	2009
A small molecule that blocks fat synthesis by inhibiting the activation of SREBP. Chemistry & biology\| PubMed ID: 19716478	2009
Synthesis of isoquinolinone-based tetracycles as poly (ADP-ribose) polymerase-1 (PARP-1) inhibitors. Bioorganic & medicinal chemistry\| PubMed ID: 19800803	2009
Oxiranylmethyloxy or thiiranylmethyloxy-azaxanthones and -acridone analogues as potential topoisomerase I inhibitors. Bioorganic & medicinal chemistry letters\| PubMed ID: 19836231	2009
2-Thienyl-4-furyl-6-aryl pyridine derivatives: synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study. Bioorganic & medicinal chemistry\| PubMed ID: 19939682	2010
2,6-Dithienyl-4-furyl pyridines: Synthesis, topoisomerase I and II inhibition, cytotoxicity, structure-activity relationship, and docking study. Bioorganic & medicinal chemistry letters\| PubMed ID: 19954977	2010
New benzoxanthone derivatives as topoisomerase inhibitors and DNA cross-linkers. Bioorganic & medicinal chemistry\| PubMed ID: 20093033	2010
Synthesis of 2-(thienyl-2-yl or -3-yl)-4-furyl-6-aryl pyridine derivatives and evaluation of their topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationsh... Bioorganic & medicinal chemistry\| PubMed ID: 20188578	2010
Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study of hydroxylated 2,4-diphenyl-6-aryl pyridines. Bioorganic & medicinal chemistry\| PubMed ID: 20392646	2010
Mutations in SOHLH1 gene associate with nonobstructive azoospermia. Human mutation\| PubMed ID: 20506135	2010
Synthesis and pharmacological evaluation of new methyloxiranylmethoxyxanthone analogues. European journal of medicinal chemistry\| PubMed ID: 20619511	2010
Synthesis and biological properties of benzo-annulated rutaecarpines. Biological & pharmaceutical bulletin\| PubMed ID: 20930379	2010
Methyl gallate exhibits potent antitumor activities by inhibiting tumor infiltration of CD4+CD25+ regulatory T cells. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 21048105	2010
Rapid and Reliable Measurement for Evaluating Directly the Reactivity of N-Acetylcysteine with Glucose Degradation Products in Peritoneal Dialysis Fluids. Analytical chemistry\| PubMed ID: 21299245	2011
Design, synthesis and docking study of 5-amino substituted indeno[1,2-c]isoquinolines as novel topoisomerase I inhibitors. Bioorganic & medicinal chemistry\| PubMed ID: 21353568	2011
A peptide binding to dimerized translationally controlled tumor protein modulates allergic reactions. Journal of molecular medicine (Berlin, Germany)\| PubMed ID: 21384150	2011
Synthesis, biological evaluation, and molecular docking study of 3-(3'-heteroatom substituted-2'-hydroxy-1'-propyloxy) xanthone analogues as novel topoisomerase IIÎ± catalytic inhibitor. European journal of medicinal chemistry\| PubMed ID: 21419530	2011
Synthesis and anti-melanogenic activity of hydroxyphenyl benzyl ether analogues. Bioorganic & medicinal chemistry\| PubMed ID: 21429753	2011
Design and evaluation of variants of the protein transduction domain originated from translationally controlled tumor protein. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences\| PubMed ID: 21440624	2011
Differential expressions of adhesive molecules and proteases define mechanisms of ovarian tumor cell matrix penetration/invasion. PloS one\| PubMed ID: 21526198	2011
Synthesis of 2,4-diaryl chromenopyridines and evaluation of their topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship. European journal of medicinal chemistry\| PubMed ID: 21601964	2011
Design and synthesis of 4-amino-2-phenylquinazolines as novel topoisomerase I inhibitors with molecular modeling. Bioorganic & medicinal chemistry\| PubMed ID: 21684168	2011
Synthesis of benzo[3,4]azepino[1,2-b]isoquinolin-9-ones from 3-arylisoquinolines via ring closing metathesis and evaluation of topoisomerase I inhibitory activity, cytotoxicity and docking s... Bioorganic & medicinal chemistry\| PubMed ID: 21873069	2011
2,4-Diaryl-5,6-dihydro-1,10-phenanthroline and 2,4-diaryl-5,6-dihydrothieno[2,3-h] quinoline derivatives for topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity ... Bioorganic chemistry\| PubMed ID: 22000119	2012
Dihydroxylated 2,4,6-triphenyl pyridines: Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study. European journal of medicinal chemistry\| PubMed ID: 22318164	2012
Neuroprotective effect of undecylenic acid extracted from Ricinus communis L. through inhibition of Î¼-calpain. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences\| PubMed ID: 22333440	2012