Jerome Zack

David Geffen School of Medicine, University of California, Los Angeles

Affiliated withUniversity of California, Los Angeles

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 19	2016

Other Publications

Article	Year
Activation of CD8 T cells induces expression of CD4, which functions as a chemotactic receptor. Blood\| PubMed ID: 11756173	2002
Effect of latent human immunodeficiency virus infection on cell surface phenotype. Journal of virology\| PubMed ID: 11799162	2002
Retrocyclin: a primate peptide that protects cells from infection by T- and M-tropic strains of HIV-1. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 11854483	2002
Cocaine enhances human immunodeficiency virus replication in a model of severe combined immunodeficient mice implanted with human peripheral blood leukocytes. The Journal of infectious diseases\| PubMed ID: 11865430	2002
Effects of prostratin on T-cell activation and human immunodeficiency virus latency. Journal of virology\| PubMed ID: 12134017	2002
Interleukin-7 induces expression of latent human immunodeficiency virus type 1 with minimal effects on T-cell phenotype. Journal of virology\| PubMed ID: 12438635	2002
HIV type 1 infection alters cytokine mRNA expression in thymus. AIDS research and human retroviruses\| PubMed ID: 12581511	2003
Human immunodeficiency virus type 1 infection and replication in normal human oral keratinocytes. Journal of virology\| PubMed ID: 12610122	2003
HIV-1 infection in peripheral blood lymphocytes (PBLs) exposed to alcohol. Virology\| PubMed ID: 12667812	2003
Molecular characterization, reactivation, and depletion of latent HIV. Immunity\| PubMed ID: 14499116	2003
Controlling false-negative errors in microarray differential expression analysis: a PRIM approach. Bioinformatics (Oxford, England)\| PubMed ID: 14512352	2003
Identification of T cell-signaling pathways that stimulate latent HIV in primary cells. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 14569007	2003
Psychological risk factors for HIV pathogenesis: mediation by the autonomic nervous system. Biological psychiatry\| PubMed ID: 14675810	2003
Impacts of epitope expression kinetics and class I downregulation on the antiviral activity of human immunodeficiency virus type 1-specific cytotoxic T lymphocytes. Journal of virology\| PubMed ID: 14694087	2004
Public health. A sound rationale needed for phase III HIV-1 vaccine trials. Science (New York, N.Y.)\| PubMed ID: 14726576	2004
The CCR5 and CXCR4 coreceptors--central to understanding the transmission and pathogenesis of human immunodeficiency virus type 1 infection. AIDS research and human retroviruses\| PubMed ID: 15000703	2004
Anti-human immunodeficiency virus hematopoietic progenitor cell-delivered ribozyme in a phase I study: myeloid and lymphoid reconstitution in human immunodeficiency virus type-1-infected pat... Human gene therapy\| PubMed ID: 15018734	2004
Stress-induced enhancement of NF-kappaB DNA-binding in the peripheral blood leukocyte pool: effects of lymphocyte redistribution. Brain, behavior, and immunity\| PubMed ID: 15050650	2004
CD4 on CD8(+) T cells directly enhances effector function and is a target for HIV infection. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15173593	2004
Alcohol enhances HIV type 1 infection in normal human oral keratinocytes by up-regulating cell-surface CXCR4 coreceptor. AIDS research and human retroviruses\| PubMed ID: 15186526	2004
Expression-based monitoring of transcription factor activity: the TELiS database. Bioinformatics (Oxford, England)\| PubMed ID: 15374858	2005
The CD4 molecule on CD8+ T lymphocytes directly enhances the immune response to viral and cellular antigens. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15731353	2005
Prostratin and bortezomib are novel inducers of latent Kaposi's sarcoma-associated herpesvirus. Antiviral therapy\| PubMed ID: 16218174	2005
beta-Adrenoreceptors reactivate Kaposi's sarcoma-associated herpesvirus lytic replication via PKA-dependent control of viral RTA. Journal of virology\| PubMed ID: 16227274	2005
Rapid size dependent deletion of foreign gene sequences inserted into attenuated HIV-1 upon infection in vivo: implications for vaccine development. Current HIV research\| PubMed ID: 16250884	2005
Serum levels of the homeostatic B cell chemokine, CXCL13, are elevated during HIV infection. Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research\| PubMed ID: 16318584	2005
PTEN negatively regulates neural stem cell self-renewal by modulating G0-G1 cell cycle entry. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16373498	2006
Rapid expression of human immunodeficiency virus following activation of latently infected cells. Journal of virology\| PubMed ID: 16415036	2006
T lineage differentiation from human embryonic stem cells. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16844782	2006
CD4 expression on activated NK cells: ligation of CD4 induces cytokine expression and cell migration. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 16951326	2006
A plea for justice for jailed medical workers. Science (New York, N.Y.)\| PubMed ID: 17062652	2006
Immediate activation fails to rescue efficient human immunodeficiency virus replication in quiescent CD4+ T cells. Journal of virology\| PubMed ID: 17229711	2007
Interleukin-15 but not interleukin-7 abrogates vaccine-induced decrease in virus level in simian immunodeficiency virus mac251-infected macaques. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 17339444	2007
Human immunodeficiency virus bearing a disrupted central DNA flap is pathogenic in vivo. Journal of virology\| PubMed ID: 17392373	2007
Primary cell model for activation-inducible human immunodeficiency virus. Journal of virology\| PubMed ID: 17475639	2007
Generation of T lineage cells from human embryonic stem cells in a feeder free system. Stem cells (Dayton, Ohio)\| PubMed ID: 18974209	2009
Eradication of HIV: current challenges and new directions. The Journal of antimicrobial chemotherapy\| PubMed ID: 18984648	2009
Short communication: Activating stimuli enhance immunotoxin-mediated killing of HIV-infected macrophages. AIDS research and human retroviruses\| PubMed ID: 19000022	2008
A functional link between Wnt signaling and SKP2-independent p27 turnover in mammary tumors. Genes & development\| PubMed ID: 19056892	2008
Differentially stimulated CD4+ T cells display altered human immunodeficiency virus infection kinetics: implications for the efficacy of antiviral agents. Journal of virology\| PubMed ID: 19129455	2009
Phase 2 gene therapy trial of an anti-HIV ribozyme in autologous CD34+ cells. Nature medicine\| PubMed ID: 19219022	2009
A self-renewal program controls the expansion of genetically unstable cancer stem cells in pluripotent stem cell-derived tumors. Stem cells (Dayton, Ohio)\| PubMed ID: 19224508	2009
CD4+ NK cells can be productively infected with HIV, leading to downregulation of CD4 expression and changes in function. Virology\| PubMed ID: 19251297	2009
Human immunodeficiency virus integration efficiency and site selection in quiescent CD4+ T cells. Journal of virology\| PubMed ID: 19369341	2009
Animal models of HIV-1 latency and persistence. Current opinion in HIV and AIDS\| PubMed ID: 19372792	2006
Engineering antigen-specific T cells from genetically modified human hematopoietic stem cells in immunodeficient mice. PloS one\| PubMed ID: 19997617	2009
A highly efficient short hairpin RNA potently down-regulates CCR5 expression in systemic lymphoid organs in the hu-BLT mouse model. Blood\| PubMed ID: 20018916	2010
Differential expression and interaction of host factors augment HIV-1 gene expression in neonatal mononuclear cells. Virology\| PubMed ID: 20138641	2010
Macrophage differentiation from embryoid bodies derived from human embryonic stem cells. Journal of stem cells\| PubMed ID: 20498689	2009
Gene expression and transcription factor profiling reveal inhibition of transcription factor cAMP-response element-binding protein by gamma-herpesvirus replication and transcription activato... The Journal of biological chemistry\| PubMed ID: 20516076	2010
CD40 ligand (CD154) incorporated into HIV virions induces activation-induced cytidine deaminase (AID) expression in human B lymphocytes. PloS one\| PubMed ID: 20625427	2010
Quiescent T cells and HIV: an unresolved relationship. Immunologic research\| PubMed ID: 20725862	2010
Female human iPSCs retain an inactive X chromosome. Cell stem cell\| PubMed ID: 20727844	2010
Stem cell-based approaches to treating HIV infection. Current opinion in HIV and AIDS\| PubMed ID: 21242896	2011
Establishment and maintenance of HIV latency: model systems and opportunities for intervention. Future virology\| PubMed ID: 21318097	2010
Activation of latent HIV using drug-loaded nanoparticles. PloS one\| PubMed ID: 21483687	2011
Single mutations in HIV integrase confer high-level resistance to raltegravir in primary human macrophages. Antimicrobial agents and chemotherapy\| PubMed ID: 21628534	2011
Phase I/II Clinical Trials Using Gene-Modified Adult Hematopoietic Stem Cells for HIV: Lessons Learnt. Stem cells international\| PubMed ID: 21716651	2011
HIV latency is influenced by regions of the viral genome outside of the long terminal repeats and regulatory genes. Virology\| PubMed ID: 21777932	2011
HIV latency in the humanized BLT mouse. Journal of virology\| PubMed ID: 22072769	2012
Genome-wide binding map of the HIV-1 Tat protein to the human genome. PloS one\| PubMed ID: 22073215	2011
Antitumor activity from antigen-specific CD8 T cells generated in vivo from genetically engineered human hematopoietic stem cells. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 22123951	2011
In vivo suppression of HIV by antigen specific T cells derived from engineered hematopoietic stem cells. PLoS pathogens\| PubMed ID: 22511873	2012
Virological evidence supporting the use of raltegravir in HIV post-exposure prophylaxis regimens. Antiviral therapy\| PubMed ID: 22820096	2012
Designed, synthetically accessible bryostatin analogues potently induce activation of latent HIV reservoirs in vitro. Nature chemistry\| PubMed ID: 22914190	2012
From skin biopsy to neurons through a pluripotent intermediate under Good Manufacturing Practice protocols. Stem cells translational medicine\| PubMed ID: 23197638	2012
Interferon-inducible cholesterol-25-hydroxylase broadly inhibits viral entry by production of 25-hydroxycholesterol. Immunity\| PubMed ID: 23273844	2013
Introduction of exogenous T-cell receptors into human hematopoietic progenitors results in exclusion of endogenous T-cell receptor expression. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 23481324	2013
HIV restriction in quiescent CD4⁺ T cells. Retrovirology\| PubMed ID: 23557201	2013
HIV/AIDS eradication. Bioorganic & medicinal chemistry letters\| PubMed ID: 23735743	2013
Highly potent, synthetically accessible prostratin analogs induce latent HIV expression in vitro and ex vivo. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23812750	2013
Cocaine exposure enhances permissiveness of quiescent T cells to HIV infection. Journal of leukocyte biology\| PubMed ID: 23817564	2013
HIV-1 infection of hematopoietic progenitor cells in vivo in humanized mice. Blood\| PubMed ID: 23886835	2013
Generation and characterization of transgene-free human induced pluripotent stem cells and conversion to putative clinical-grade status. Stem cell research & therapy\| PubMed ID: 23890092	2013
Adoptive transfer of MART-1 T-cell receptor transgenic lymphocytes and dendritic cell vaccination in patients with metastatic melanoma. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 24634374	2014
CD4 ligation on human blood monocytes triggers macrophage differentiation and enhances HIV infection. Journal of virology\| PubMed ID: 24942581	2014
Bioengineered vaults: self-assembling protein shell-lipophilic core nanoparticles for drug delivery. ACS nano\| PubMed ID: 25061969	2014
Neutralizing the HIV reservoir. Cell\| PubMed ID: 25171398	2014
Double trouble: HIV latency and CTL escape. Cell host & microbe\| PubMed ID: 25674977	2015
Studies of retroviral infection in humanized mice. Virology\| PubMed ID: 25680625	2015
RNAi-Mediated CCR5 Knockdown Provides HIV-1 Resistance to Memory T Cells in Humanized BLT Mice. Molecular therapy. Nucleic acids\| PubMed ID: 25689223	2015
Cocaine exposure impairs multilineage hematopoiesis of human hematopoietic progenitor cells mediated by the sigma-1 receptor [corrected]. Scientific reports\| PubMed ID: 25728014	2015
Lymphoid regeneration from gene-corrected SCID-X1 subject-derived iPSCs. Cell stem cell\| PubMed ID: 25772073	2015
Noninvasive detection of tumor-infiltrating T cells by PET reporter imaging. The Journal of clinical investigation\| PubMed ID: 25822024	2015
HIV-specific Immunity Derived From Chimeric Antigen Receptor-engineered Stem Cells. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 26050990	2015
Cocaine-mediated impact on HIV infection in humanized BLT mice. Scientific reports\| PubMed ID: 26084721	2015
Corrigendum: Cocaine exposure impairs multilineage hematopoiesis of human hematopoietic progenitor cells mediated by the sigma-1 receptor. Scientific reports\| PubMed ID: 26166708	2015
Disruption of Type I Interferon Induction by HIV Infection of T Cells. PloS one\| PubMed ID: 26375588	2015
Improvements and Limitations of Humanized Mouse Models for HIV Research: NIH/NIAID "Meet the Experts" 2015 Workshop Summary. AIDS research and human retroviruses\| PubMed ID: 26670361	2016
A Single CRISPR-Cas9 Deletion Strategy that Targets the Majority of DMD Patients Restores Dystrophin Function in hiPSC-Derived Muscle Cells. Cell stem cell\| PubMed ID: 26877224	2016
Medial HOXA genes demarcate haematopoietic stem cell fate during human development. Nature cell biology\| PubMed ID: 27183470	2016
HIV-1-Specific Chimeric Antigen Receptors Based on Broadly-Neutralizing Antibodies. Journal of virology\| PubMed ID: 27226366	2016