Sang-Jun Ha

Department of Biochemistry, Yonsei University

Affiliated withYonsei University Yonsei University

Research Area

Biography

Sang-Jun Ha has not added Biography.
If you are Sang-Jun Ha and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 1	2016

Other Publications

Article	Year
IL-23 induces stronger sustained CTL and Th1 immune responses than IL-12 in hepatitis C virus envelope protein 2 DNA immunization. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 14688363	2004
IL-12 priming during in vitro antigenic stimulation changes properties of CD8 T cells and increases generation of effector and memory cells. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 14978082	2004
Enhancement of interleukin-12 gene-based tumor immunotherapy by the reduced secretion of p40 subunit and the combination with farnesyltransferase inhibitor. Human gene therapy\| PubMed ID: 15812228	2005
Stimulation history dictates memory CD8 T cell phenotype: implications for prime-boost vaccination. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 16818737	2006
Enhanced immunogenicity and protective efficacy with the use of interleukin-12-encapsulated microspheres plus AS01B in tuberculosis subunit vaccination. Infection and immunity\| PubMed ID: 16861689	2006
Molecular signature of CD8+ T cell exhaustion during chronic viral infection. Immunity\| PubMed ID: 17950003	2007
Enhancing therapeutic vaccination by blocking PD-1-mediated inhibitory signals during chronic infection. The Journal of experimental medicine\| PubMed ID: 18332181	2008
Manipulating both the inhibitory and stimulatory immune system towards the success of therapeutic vaccination against chronic viral infections. Immunological reviews\| PubMed ID: 18613845	2008
IL-10 and PD-L1 operate through distinct pathways to suppress T-cell activity during persistent viral infection. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19075244	2008
Impact of epitope escape on PD-1 expression and CD8 T-cell exhaustion during chronic infection. Journal of virology\| PubMed ID: 19211743	2009
Visualizing antigen-specific and infected cells in situ predicts outcomes in early viral infection. Science (New York, N.Y.)\| PubMed ID: 19325114	2009
PD-L1 has distinct functions in hematopoietic and nonhematopoietic cells in regulating T cell responses during chronic infection in mice. The Journal of clinical investigation\| PubMed ID: 20551512	2010
Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 20679213	2010
Lung cancer in never smokers: change of a mindset in the molecular era. Lung cancer (Amsterdam, Netherlands)\| PubMed ID: 21272954	2011
Mechanism of T cell exhaustion in a chronic environment. BMB reports\| PubMed ID: 21524346	2011
Distinct clinical features and outcomes in never-smokers with nonsmall cell lung cancer who harbor EGFR or KRAS mutations or ALK rearrangement. Cancer\| PubMed ID: 21720997	2012
4-1BB signaling synergizes with programmed death ligand 1 blockade to augment CD8 T cell responses during chronic viral infection. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 21742975	2011
Chronic virus infection enforces demethylation of the locus that encodes PD-1 in antigen-specific CD8(+) T cells. Immunity\| PubMed ID: 21943489	2011
Co-immunization of plasmid DNA encoding IL-12 and IL-18 with Bacillus Calmette-Guérin vaccine against progressive tuberculosis. Yonsei medical journal\| PubMed ID: 22028167	2011
Antigen-specific CD4 T-cell help rescues exhausted CD8 T cells during chronic viral infection. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 22160724	2011
High EGFR gene copy number and skin rash as predictive markers for EGFR tyrosine kinase inhibitors in patients with advanced squamous cell lung carcinoma. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 22271877	2012
Mind bomb-1 in dendritic cells is specifically required for Notch-mediated T helper type 2 differentiation. PloS one\| PubMed ID: 22558446	2012
Activation of IL-6R/JAK1/STAT3 signaling induces de novo resistance to irreversible EGFR inhibitors in non-small cell lung cancer with T790M resistance mutation. Molecular cancer therapeutics\| PubMed ID: 22891040	2012
Tumor-infiltrating regulatory T cells delineated by upregulation of PD-1 and inhibitory receptors. Cellular immunology\| PubMed ID: 23121978	2012
Fibroblast growth factor receptor 1 gene amplification is associated with poor survival and cigarette smoking dosage in patients with resected squamous cell lung cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 23182986	2013
A phase I trial of gefitinib and nimotuzumab in patients with advanced non-small cell lung cancer (NSCLC). Lung cancer (Amsterdam, Netherlands)\| PubMed ID: 23261229	2013
Recruitment of monocytes/macrophages in different tumor microenvironments. Biochimica et biophysica acta\| PubMed ID: 23287570	2013
Interleukin-21 is a critical cytokine for the generation of virus-specific long-lived plasma cells. Journal of virology\| PubMed ID: 23637417	2013
PD-L1 blockade synergizes with IL-2 therapy in reinvigorating exhausted T cells. The Journal of clinical investigation\| PubMed ID: 23676462	2013
The impact of cigarette smoking on the frequency of and qualitative differences in KRAS mutations in Korean patients with lung adenocarcinoma. Yonsei medical journal\| PubMed ID: 23709419	2013
Egr2 induced during DC development acts as an intrinsic negative regulator of DC immunogenicity. European journal of immunology\| PubMed ID: 23716134	2013
Negative regulation of type I IFN expression by OASL1 permits chronic viral infection and CD8⁺ T-cell exhaustion. PLoS pathogens\| PubMed ID: 23874199	2013
Differentiation of antigen-specific T cells with limited functional capacity during Mycobacterium tuberculosis infection. Infection and immunity\| PubMed ID: 24126533	2014
Highly efficient gene knockout in mice and zebrafish with RNA-guided endonucleases. Genome research\| PubMed ID: 24253447	2014
Regulatory T cells-an important target for cancer immunotherapy. Nature reviews. Clinical oncology\| PubMed ID: 24781417	2014
Direct endothelial junction restoration results in significant tumor vascular normalization and metastasis inhibition in mice. Oncotarget\| PubMed ID: 24811731	2014
Enhancing T Cell Immune Responses by B Cell-based Therapeutic Vaccine Against Chronic Virus Infection. Immune network\| PubMed ID: 25177253	2014
Inhibition of IL-17A suppresses enhanced-tumor growth in low dose pre-irradiated tumor beds. PloS one\| PubMed ID: 25181290	2014
Peptidylarginine deiminase inhibition impairs Toll-like receptor agonist-induced functional maturation of dendritic cells, resulting in the loss of T cell-proliferative capacity: a partial m... Journal of leukocyte biology\| PubMed ID: 25420918	2015
Discrimination between active and latent tuberculosis based on ratio of antigen-specific to mitogen-induced IP-10 production. Journal of clinical microbiology\| PubMed ID: 25428147	2015
Diagnostic performance of a cytokine and IFN-γ-induced chemokine mRNA assay after Mycobacterium tuberculosis-specific antigen stimulation in whole blood from infected individuals. The Journal of molecular diagnostics : JMD\| PubMed ID: 25528189	2015
Identification of a subnuclear body involved in sequence-specific cytokine RNA processing. Nature communications\| PubMed ID: 25557830	2015
PD-1 upregulated on regulatory T cells during chronic virus infection enhances the suppression of CD8+ T cell immune response via the interaction with PD-L1 expressed on CD8+ T cells. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 25934860	2015
PD-1: Dual guard for immunopathology. Oncotarget\| PubMed ID: 26318040	2015
Altered Biological Potential and Radioresponse of Murine Tumors in Different Microenvironments. Cancer research and treatment : official journal of Korean Cancer Association\| PubMed ID: 26323643	2016
IL-4 Induced Innate CD8+ T Cells Control Persistent Viral Infection. PLoS pathogens\| PubMed ID: 26452143	2015
AMIGO2, a novel membrane anchor of PDK1, controls cell survival and angiogenesis via Akt activation. The Journal of cell biology\| PubMed ID: 26553931	2015
A small molecule inhibitor for ATPase activity of Hsp70 and Hsc70 enhances the immune response to protein antigens. Scientific reports\| PubMed ID: 26631605	2015
Correction: PD-1 Upregulated on Regulatory T Cells during Chronic Virus Infection Enhances the Suppression of CD8+ T Cell Immune Response via the Interaction with PD-L1 Expressed on CD8+ T C... Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 26637664	2015
Generation of Tolerogenic Dendritic Cells and Their Therapeutic Applications. Immune network\| PubMed ID: 26937232	2016
Effect of IL-4 on the Development and Function of Memory-like CD8 T Cells in the Peripheral Lymphoid Tissues. Immune network\| PubMed ID: 27162529	2016
Cisplatin induces tolerogenic dendritic cells in response to TLR agonists via the abundant production of IL-10, thereby promoting Th2- and Tr1-biased T-cell immunity. Oncotarget\| PubMed ID: 27172902	2016
Cell Type Preference of a Novel Human Derived Cell-Permeable Peptide dNP2 and TAT in Murine Splenic Immune Cells. PloS one\| PubMed ID: 27186978	2016