Jongyoon Han

Department of Electrical Engineering and Computer Science, MIT

Affiliated withMIT Massachusetts Institute of Technology

Research Area

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 1	2016
Publication title Cited by 2	2018

Other Publications

Article	Year
Characterization and optimization of an entropic trap for DNA separation. Analytical chemistry\| PubMed ID: 11811414	2002
Two-dimensional protein separation with advanced sample and buffer isolation using microfluidic valves. Analytical chemistry\| PubMed ID: 15283583	2004
Rapid protein separations in ultra-short microchannels: microchip sodium dodecyl sulfate-polyacrylamide gel electrophoresis and isoelectric focusing. Journal of chromatography. A\| PubMed ID: 15499934	2004
Million-fold preconcentration of proteins and peptides by nanofluidic filter. Analytical chemistry\| PubMed ID: 16013838	2005
Fabrication and characterization of 20 nm planar nanofluidic channels by glass-glass and glass-silicon bonding. Lab on a chip\| PubMed ID: 16027934	2005
Continuous-flow pI-based sorting of proteins and peptides in a microfluidic chip using diffusion potential. Analytical chemistry\| PubMed ID: 16737204	2006
Molecular sieving in periodic free-energy landscapes created by patterned nanofilter arrays. Physical review letters\| PubMed ID: 16907412	2006
Electrohydrodynamic generation and delivery of monodisperse picoliter droplets using a poly(dimethylsiloxane) microchip. Analytical chemistry\| PubMed ID: 17134134	2006
Biomolecule separation by steric hindrance using nanofluidic filters. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference\| PubMed ID: 17270810	2004
Patterning of proteins and cells on functionalized surfaces prepared by polyelectrolyte multilayers and micromolding in capillaries. Biosensors & bioelectronics\| PubMed ID: 17400439	2007
Poly(dimethylsiloxane)-based protein preconcentration using a nanogap generated by junction gap breakdown. Analytical chemistry\| PubMed ID: 17628080	2007
Concentration polarization and nonlinear electrokinetic flow near a nanofluidic channel. Physical review letters\| PubMed ID: 17678369	2007
Electrical detection of fast reaction kinetics in nanochannels with an induced flow. Nano letters\| PubMed ID: 17997589	2007
Molecular sieving using nanofilters: past, present and future. Lab on a chip\| PubMed ID: 18094759	2008
Continuum transport model of Ogston sieving in patterned nanofilter arrays for separation of rod-like biomolecules. Electrophoresis\| PubMed ID: 18203240	2008
Pre-binding dynamic range and sensitivity enhancement for immuno-sensors using nanofluidic preconcentrator. Lab on a chip\| PubMed ID: 18305855	2008
Increase of reaction rate and sensitivity of low-abundance enzyme assay using micro/nanofluidic preconcentration chip. Analytical chemistry\| PubMed ID: 18358012	2008
Multiplexed proteomic sample preconcentration device using surface-patterned ion-selective membrane. Lab on a chip\| PubMed ID: 18369515	2008
Self-sealed vertical polymeric nanoporous-junctions for high-throughput nanofluidic applications. Analytical chemistry\| PubMed ID: 18380489	2008
Artificial molecular sieves and filters: a new paradigm for biomolecule separation. Trends in biotechnology\| PubMed ID: 18430480	2008
A patterned anisotropic nanofluidic sieving structure for continuous-flow separation of DNA and proteins. Nature nanotechnology\| PubMed ID: 18654231	2007
Simulation of DNA electrophoresis in systems of large number of solvent particles by coarse-grained hybrid molecular dynamics approach. Journal of computational chemistry\| PubMed ID: 18773412	2009
A Nanofilter Array Chip for Fast Gel-Free Biomolecule Separation. Applied physics letters\| PubMed ID: 18846250	2005
Decreasing effective nanofluidic filter size by modulating electrical double layers: separation enhancement in microfabricated nanofluidic filters. Electrophoresis\| PubMed ID: 19016242	2008
Transport of biomolecules in asymmetric nanofilter arrays. Analytical and bioanalytical chemistry\| PubMed ID: 19127359	2009
Realistic simulations of combined DNA electrophoretic flow and EOF in nano-fluidic devices. Electrophoresis\| PubMed ID: 19130595	2008
Massively-parallel ultra-high-aspect-ratio nanochannels as mesoporous membranes. Lab on a chip\| PubMed ID: 19190794	2009
Amplified electrokinetic response by concentration polarization near nanofluidic channel. Langmuir : the ACS journal of surfaces and colloids\| PubMed ID: 19358584	2009
Rapid quantification of disease-marker proteins using continuous-flow immunoseparation in a nanosieve fluidic device. Analytical chemistry\| PubMed ID: 19627123	2009
Microfluidic concentration-enhanced cellular kinase activity assay. Journal of the American Chemical Society\| PubMed ID: 19722608	2009
Continuous-flow bioseparation using microfabricated anisotropic nanofluidic sieving structures. Nature protocols\| PubMed ID: 19876028	2009
Analytical description of Ogston-regime biomolecule separation using nanofilters and nanopores. Physical review. E, Statistical, nonlinear, and soft matter physics\| PubMed ID: 19905346	2009
Stabilization of ion concentration polarization using a heterogeneous nanoporous junction. Nano letters\| PubMed ID: 20017532	2010
Free-flow zone electrophoresis of peptides and proteins in PDMS microchip for narrow pI range sample prefractionation coupled with mass spectrometry. Analytical chemistry\| PubMed ID: 20163146	2010
Nanofluidic concentration devices for biomolecules utilizing ion concentration polarization: theory, fabrication, and applications. Chemical Society reviews\| PubMed ID: 20179814	2010
Direct seawater desalination by ion concentration polarization. Nature nanotechnology\| PubMed ID: 20305644	2010
Increasing the sensitivity of enzyme-linked immunosorbent assay using multiplexed electrokinetic concentrator. Analytical chemistry\| PubMed ID: 20307052	2010
Microfluidics for cell separation. Medical & biological engineering & computing\| PubMed ID: 20414811	2010
Capillary-valve-based fabrication of ion-selective membrane junction for electrokinetic sample preconcentration in PDMS chip. Lab on a chip\| PubMed ID: 20480116	2010
Deformability based cell margination--a simple microfluidic design for malaria-infected erythrocyte separation. Lab on a chip\| PubMed ID: 20689864	2010
Micro and nanotechnology for biological and biomedical applications. Medical & biological engineering & computing\| PubMed ID: 20844973	2010
Concentration-enhanced rapid detection of human chorionic gonadotropin (hCG) on a Au surface using a nanofluidic preconcentrator. Microfluidics and nanofluidics\| PubMed ID: 20953263	2010
Shape and Biomechanical Characteristics of Human Red Blood Cells in Health and Disease. MRS bulletin / Materials Research Society\| PubMed ID: 21151848	2010
A microfabricated deformability-based flow cytometer with application to malaria. Lab on a chip\| PubMed ID: 21293801	2011
Massively parallel concentration device for multiplexed immunoassays. Lab on a chip\| PubMed ID: 21321747	2011
High-throughput cell cycle synchronization using inertial forces in spiral microchannels. Lab on a chip\| PubMed ID: 21336340	2011
Dispersive transport of biomolecules in periodic energy landscapes with application to nanofilter sieving arrays. Electrophoresis\| PubMed ID: 21341285	2011
Pinched flow coupled shear-modulated inertial microfluidics for high-throughput rare blood cell separation. Lab on a chip\| PubMed ID: 21505682	2011
Enhancing protease activity assay in droplet-based microfluidics using a biomolecule concentrator. Journal of the American Chemical Society\| PubMed ID: 21671557	2011
Non-linear and linear enhancement of enzymatic reaction kinetics using a biomolecule concentrator. Lab on a chip\| PubMed ID: 21677981	2011
Continuous signal enhancement for sensitive aptamer affinity probe electrophoresis assay using electrokinetic concentration. Analytical chemistry\| PubMed ID: 21809885	2011
Continuous-flow biomolecule and cell concentrator by ion concentration polarization. Analytical chemistry\| PubMed ID: 21854051	2011
Electrochemical activation and inhibition of neuromuscular systems through modulation of ion concentrations with ion-selective membranes. Nature materials\| PubMed ID: 22019944	2011
Adhesive-based liquid metal radio-frequency microcoil for magnetic resonance relaxometry measurement. Lab on a chip\| PubMed ID: 22116258	2012
Layer-by-layer deposition of all-nanoparticle multilayers in confined geometries. ACS applied materials & interfaces\| PubMed ID: 22181001	2012
A microfluidics approach towards high-throughput pathogen removal from blood using margination. Biomicrofluidics\| PubMed ID: 22655023	2012
Nanotechnology in plastic surgery. Plastic and reconstructive surgery\| PubMed ID: 22878482	2012
A microfluidic in vitro system for the quantitative study of the stomach mucus barrier function. Lab on a chip\| PubMed ID: 22878692	2012
Nanofluidic preconcentration device in a straight microchannel using ion concentration polarization. Lab on a chip\| PubMed ID: 22907316	2012
Pf155/RESA protein influences the dynamic microcirculatory behavior of ring-stage Plasmodium falciparum infected red blood cells. Scientific reports\| PubMed ID: 22937223	2012
Continuous-flow biomolecule concentration and detection in a slanted nanofilter array. Lab on a chip\| PubMed ID: 22955573	2012
Development of miniaturized, portable magnetic resonance relaxometry system for point-of-care medical diagnosis. The Review of scientific instruments\| PubMed ID: 23020427	2012
Separation of leukocytes from blood using spiral channel with trapezoid cross-section. Analytical chemistry\| PubMed ID: 23025404	2012
Multi-vortical flow inducing electrokinetic instability in ion concentration polarization layer. Nanoscale\| PubMed ID: 23085964	2012
Multiplexed protease activity assay for low-volume clinical samples using droplet-based microfluidics and its application to endometriosis. Journal of the American Chemical Society\| PubMed ID: 23157326	2013
Direct numerical simulation of electroconvective instability and hysteretic current-voltage response of a permselective membrane. Physical review. E, Statistical, nonlinear, and soft matter physics\| PubMed ID: 23214680	2012
Tunable ionic transport for a triangular nanochannel in a polymeric nanofluidic system. ACS nano\| PubMed ID: 23244067	2013
Dynamic deformability of Plasmodium falciparum-infected erythrocytes exposed to artesunate in vitro. Integrative biology : quantitative biosciences from nano to macro\| PubMed ID: 23254624	2013
Isolation and retrieval of circulating tumor cells using centrifugal forces. Scientific reports\| PubMed ID: 23405273	2013
Isoporous micro/nanoengineered membranes. ACS nano\| PubMed ID: 23442009	2013
Spiral microchannel with rectangular and trapezoidal cross-sections for size based particle separation. Scientific reports\| PubMed ID: 23502529	2013
ADAM-10 and -17 regulate endometriotic cell migration via concerted ligand and receptor shedding feedback on kinase signaling. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23674691	2013
Slanted spiral microfluidics for the ultra-fast, label-free isolation of circulating tumor cells. Lab on a chip\| PubMed ID: 23949794	2014
Spatial configuration and composition of charge modulates transport into a mucin hydrogel barrier. Biophysical journal\| PubMed ID: 24047986	2013
Tunable membranes for free-flow zone electrophoresis in PDMS microchip using guided self-assembly of silica microbeads. Analytical chemistry\| PubMed ID: 24251795	2013
Microfabricated nerve-electrode interfaces in neural prosthetics and neural engineering. Biotechnology & genetic engineering reviews\| PubMed ID: 24568276	2013
Microfluidic probe for single-cell analysis in adherent tissue culture. Nature communications\| PubMed ID: 24594667	2014
In vivo splenic clearance correlates with in vitro deformability of red blood cells from Plasmodium yoelii-infected mice. Infection and immunity\| PubMed ID: 24686065	2014
An ultra-high-throughput spiral microfluidic biochip for the enrichment of circulating tumor cells. The Analyst\| PubMed ID: 24840240	2014
Clinical validation of an ultra high-throughput spiral microfluidics for the detection and enrichment of viable circulating tumor cells. PloS one\| PubMed ID: 24999991	2014
Detecting kinase activities from single cell lysate using concentration-enhanced mobility shift assay. Analytical chemistry\| PubMed ID: 25025773	2014
Direct in vivo electrochemical detection of haemoglobin in red blood cells. Scientific reports\| PubMed ID: 25163492	2014
Shear flow of an electrically charged fluid by ion concentration polarization: scaling laws for electroconvective vortices. Physical review letters\| PubMed ID: 25166542	2013
Micromagnetic resonance relaxometry for rapid label-free malaria diagnosis. Nature medicine\| PubMed ID: 25173428	2014
Multivariate biophysical markers predictive of mesenchymal stromal cell multipotency. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 25298531	2014
Towards microfluidic-based depletion of stiff and fragile human red cells that accumulate during blood storage. Lab on a chip\| PubMed ID: 25406942	2015
Bone marrow regeneration promoted by biophysically sorted osteoprogenitors from mesenchymal stromal cells. Stem cells translational medicine\| PubMed ID: 25411477	2015
Jetting microfluidics with size-sorting capability for single-cell protease detection. Biosensors & bioelectronics\| PubMed ID: 25460876	2015
Malaria detection using inertial microfluidics. Lab on a chip\| PubMed ID: 25537768	2015
Capacitive deionization on-chip as a method for microfluidic sample preparation. Lab on a chip\| PubMed ID: 25607349	2015
Enhanced transport of materials into enamel nanopores via electrokinetic flow. Journal of dental research\| PubMed ID: 25691072	2015
High-throughput protease activity cytometry reveals dose-dependent heterogeneity in PMA-mediated ADAM17 activation. Integrative biology : quantitative biosciences from nano to macro\| PubMed ID: 25832727	2015
Direct detection and drug-resistance profiling of bacteremias using inertial microfluidics. Lab on a chip\| PubMed ID: 25882432	2015
Enhancing malaria diagnosis through microfluidic cell enrichment and magnetic resonance relaxometry detection. Scientific reports\| PubMed ID: 26081638	2015
Identification of malaria parasite-infected red blood cell surface aptamers by inertial microfluidic SELEX (I-SELEX). Scientific reports\| PubMed ID: 26126714	2015
Membrane-less microfiltration using inertial microfluidics. Scientific reports\| PubMed ID: 26154774	2015
Large-Volume Microfluidic Cell Sorting for Biomedical Applications. Annual review of biomedical engineering\| PubMed ID: 26194427	2015
Reply to "Considerations regarding the micromagnetic resonance relaxometry technique for rapid label-free malaria diagnosis". Nature medicine\| PubMed ID: 26646491	2015
Ultra-fast, label-free isolation of circulating tumor cells from blood using spiral microfluidics. Nature protocols\| PubMed ID: 26678083	2016
Broad spectrum immunomodulation using biomimetic blood cell margination for sepsis therapy. Lab on a chip\| PubMed ID: 26767950	2016
Study of individual erythrocyte deformability susceptibility to INFeD and ethanol using a microfluidic chip. Scientific reports\| PubMed ID: 26964754	2016
Multiplexed Affinity-Based Separation of Proteins and Cells Using Inertial Microfluidics. Scientific reports\| PubMed ID: 27026280	2016
Gene disruption of dematin causes precipitous loss of erythrocyte membrane stability and severe hemolytic anemia. Blood\| PubMed ID: 27073223	2016
Helical vortex formation in three-dimensional electrochemical systems with ion-selective membranes. Physical review. E\| PubMed ID: 27078454	2016
Enhanced Salt Removal by Unipolar Ion Conduction in Ion Concentration Polarization Desalination. Scientific reports\| PubMed ID: 27158057	2016
Differential Spleen Remodeling Associated with Different Levels of Parasite Virulence Controls Disease Outcome in Malaria Parasite Infections. mSphere\| PubMed ID: 27303680	2016
Liquid biopsy and therapeutic response: Circulating tumor cell cultures for evaluation of anticancer treatment. Science advances\| PubMed ID: 27453941	2016
Purification of High Salinity Brine by Multi-Stage Ion Concentration Polarization Desalination. Scientific reports\| PubMed ID: 27545955	2016
Monitoring sepsis using electrical cell profiling. Lab on a chip\| PubMed ID: 27722555	2016
Continuous micro-vortex-based nanoparticle manipulation via focused surface acoustic waves. Lab on a chip\| PubMed ID: 27883136	2016
Direct evidence for cancer-cell-autonomous extracellular protein catabolism in pancreatic tumors. Nature medicine\| PubMed ID: 28024083	2017
Differentiation of Club Cells to Alveolar Epithelial Cells In Vitro. Scientific reports\| PubMed ID: 28128362	2017
Group 6 Layered Transition-Metal Dichalcogenides in Lab-on-a-Chip Devices: 1T-Phase WS for Microfluidics Non-Enzymatic Detection of Hydrogen Peroxide. Analytical chemistry\| PubMed ID: 28394576	2017
Patient-Derived Airway Secretion Dissociation Technique To Isolate and Concentrate Immune Cells Using Closed-Loop Inertial Microfluidics. Analytical chemistry\| PubMed ID: 28402103	2017
Integrated pretreatment and desalination by electrocoagulation (EC)-ion concentration polarization (ICP) hybrid. Lab on a chip\| PubMed ID: 28518195	2017
Nanofluidic device for continuous multiparameter quality assurance of biologics. Nature nanotechnology\| PubMed ID: 28530715	2017
Microfluidic Cell Retention Device for Perfusion of Mammalian Suspension Culture. Scientific reports\| PubMed ID: 28751635	2017
Nanofluidic crystals: nanofluidics in a close-packed nanoparticle array. Lab on a chip\| PubMed ID: 28752878	2017
Enabling electrical biomolecular detection in high ionic concentrations and enhancement of the detection limit thereof by coupling a nanofluidic crystal with reconfigurable ion concentration... Lab on a chip\| PubMed ID: 28983543	2017
Characterizing Deformability and Electrical Impedance of Cancer Cells in a Microfluidic Device. Analytical chemistry\| PubMed ID: 29172457	2018
Expansion of patient-derived circulating tumor cells from liquid biopsies using a CTC microfluidic culture device. Nature protocols\| PubMed ID: 29215634	2018
Force fields of charged particles in micro-nanofluidic preconcentration systems. AIP advances\| PubMed ID: 29308297	2017
Thrombospondin-1 protects against pathogen-induced lung injury by limiting extracellular matrix proteolysis. JCI insight\| PubMed ID: 29415890	2018
Microfluidic label-free selection of mesenchymal stem cell subpopulation during culture expansion extends the chondrogenic potential in vitro. Lab on a chip\| PubMed ID: 29459915	2018
Characterization and application of size-sorted zonal chondrocytes for articular cartilage regeneration. Biomaterials\| PubMed ID: 29518707	2018
Negative Selection by Spiral Inertial Microfluidics Improves Viral Recovery and Sequencing from Blood. Analytical chemistry\| PubMed ID: 29536737	2018
Self-Aligned Acoustofluidic Particle Focusing and Patterning in Microfluidic Channels from Channel-Based Acoustic Waveguides. Physical review letters\| PubMed ID: 29542954	2018
Deciphering ion concentration polarization-based electrokinetic molecular concentration at the micro-nanofluidic interface: theoretical limits and scaling laws. Nanoscale\| PubMed ID: 29790562	2018