Wolfgang W. A. Schamel

Centre for Biological Signalling Studies (bioss) and Biology III, University of Freiburg

Affiliated withUniversity of Freiburg Max-Planck-Institute of Immunology and Epigenetics

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 92	2011

Other Publications

Article	Year
Recruitment of Nck by CD3 epsilon reveals a ligand-induced conformational change essential for T cell receptor signaling and synapse formation. Cell\| PubMed ID: 12110186	2002
Amplification of B cell antigen receptor signaling by a Syk/ITAM positive feedback loop. Molecular cell\| PubMed ID: 12453414	2002
Initiation of TCR signaling: regulation within CD3 dimers. Immunological reviews\| PubMed ID: 12614350	2003
A high-molecular-weight complex of membrane proteins BAP29/BAP31 is involved in the retention of membrane-bound IgD in the endoplasmic reticulum. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12886015	2003
Two-dimensional Blue native/SDS gel electrophoresis of multi-protein complexes from whole cellular lysates: a proteomics approach. Molecular & cellular proteomics : MCP\| PubMed ID: 14665681	2004
Biochemical differences in the alphabeta T cell receptor.CD3 surface complex between CD8+ and CD4+ human mature T lymphocytes. The Journal of biological chemistry\| PubMed ID: 15060077	2004
Adenosine and cAMP are potent inhibitors of the NF-kappa B pathway downstream of immunoreceptors. European journal of immunology\| PubMed ID: 15580656	2005
Coexistence of multivalent and monovalent TCRs explains high sensitivity and wide range of response. The Journal of experimental medicine\| PubMed ID: 16087711	2005
Subproteomic analysis of metal-interacting proteins in human B cells. Proteomics\| PubMed ID: 16097032	2005
Differences in pairing and cluster formation of T cell receptor alpha- and beta-chains in T cell clones and fusion hybridomas. Immunobiology\| PubMed ID: 16323705	2005
Two dimensional Blue Native-/SDS-PAGE analysis of SLP family adaptor protein complexes. Immunology letters\| PubMed ID: 16356554	2006
A conformation- and avidity-based proofreading mechanism for the TCR-CD3 complex. Trends in immunology\| PubMed ID: 16527543	2006
T-cell antigen-receptor stoichiometry: pre-clustering for sensitivity. EMBO reports\| PubMed ID: 16670682	2006
Blue native polyacrylamide gel electrophoresis (BN-PAGE) for the identification and analysis of multiprotein complexes. Science's STKE : signal transduction knowledge environment\| PubMed ID: 16868305	2006
Identification of disulfide bonds in the Ig-alpha/Ig-beta component of the B cell antigen receptor using the Drosophila S2 cell reconstitution system. International immunology\| PubMed ID: 16877534	2006
Overlapping functions of human CD3delta and mouse CD3gamma in alphabeta T-cell development revealed in a humanized CD3gamma-mouse. Blood\| PubMed ID: 16888097	2006
Full activation of the T cell receptor requires both clustering and conformational changes at CD3. Immunity\| PubMed ID: 17188005	2007
High-sensitivity detection and quantitative analysis of native protein-protein interactions and multiprotein complexes by flow cytometry. Science's STKE : signal transduction knowledge environment\| PubMed ID: 17551170	2007
A native antibody-based mobility-shift technique (NAMOS-assay) to determine the stoichiometry of multiprotein complexes. Journal of immunological methods\| PubMed ID: 17568608	2007
Different composition of the human and the mouse gammadelta T cell receptor explains different phenotypes of CD3gamma and CD3delta immunodeficiencies. The Journal of experimental medicine\| PubMed ID: 17923503	2007
The TCR binding site does move. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17925433	2007
A permissive geometry model for TCR-CD3 activation. Trends in biochemical sciences\| PubMed ID: 18201888	2008
The short length of the extracellular domain of zeta is crucial for T cell antigen receptor function. Immunology letters\| PubMed ID: 18207249	2008
The extracellular part of zeta is buried in the T cell antigen receptor complex. Immunology letters\| PubMed ID: 18215426	2008
T cell receptor engagement triggers its CD3epsilon and CD3zeta subunits to adopt a compact, locked conformation. PloS one\| PubMed ID: 18320063	2008
Two-dimensional blue native polyacrylamide gel electrophoresis. Current protocols in cell biology / editorial board, Juan S. Bonifacino ... [et al.]\| PubMed ID: 18360818	2008
Differential antibody binding to the surface alphabetaTCR.CD3 complex of CD4+ and CD8+ T lymphocytes is conserved in mammals and associated with differential glycosylation. International immunology\| PubMed ID: 18653700	2008
Purification of the T cell antigen receptor and analysis by blue-native PAGE. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 19048218	2009
Clustering models. Advances in experimental medicine and biology\| PubMed ID: 19065784	2008
Segregation models. Advances in experimental medicine and biology\| PubMed ID: 19065785	2008
Permissive geometry model. Advances in experimental medicine and biology\| PubMed ID: 19065789	2008
Detection of protein complex interactions via a Blue Native-PAGE retardation assay. Analytical biochemistry\| PubMed ID: 19482002	2009
Target-dependent T-cell activation by coligation with a PSMA x CD3 diabody induces lysis of prostate cancer cells. Journal of immunotherapy (Hagerstown, Md. : 1997)\| PubMed ID: 19483653	2009
Models of antigen receptor activation in the design of vaccines. Current pharmaceutical design\| PubMed ID: 19860673	2009
Analysis of novel phospho-ITAM specific antibodies in a S2 reconstitution system for TCR-CD3 signalling. Immunology letters\| PubMed ID: 20005895	2010
Detection of phosphorylated T and B cell antigen receptor species by Phos-tag SDS- and Blue Native-PAGE. Immunology letters\| PubMed ID: 20005898	2010
Low-valency, but not monovalent, antigens trigger the B-cell antigen receptor (BCR). International immunology\| PubMed ID: 20145007	2010
Innate, antigen-independent role for T cells in the activation of the immune system by Propionibacterium acnes. European journal of immunology\| PubMed ID: 20690177	2010
Pre-clustered TCR complexes. FEBS letters\| PubMed ID: 20828560	2010
Quantitative analysis of protein phosphorylations and interactions by multi-colour IP-FCM as an input for kinetic modelling of signalling networks. PloS one\| PubMed ID: 21829558	2011
A new vampire saga: the molecular mechanism of T cell trogocytosis. Immunity\| PubMed ID: 21867922	2011
Increased sensitivity of antigen-experienced T cells through the enrichment of oligomeric T cell receptor complexes. Immunity\| PubMed ID: 21903423	2011
A leaky mutation in CD3D differentially affects Î±Î² and Î³Î´ T cells and leads to a TÎ±Î²-TÎ³Î´+B+NK+ human SCID. The Journal of clinical investigation\| PubMed ID: 21926461	2011