Monica Driscoll

Department of Molecular Biology and Biochemistry, Rutgers University

Research Area

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 18	2016
Publication title Cited by 28	2020

Other Publications

Article	Year
Neuropathology of degenerative cell death in Caenorhabditis elegans. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 8994058	1997
UNC-4/UNC-37-dependent repression of motor neuron-specific genes controls synaptic choice in Caenorhabditis elegans. Genes & development\| PubMed ID: 10557206	1999
Caloric restriction and lifespan: a role for protein turnover? Mechanisms of ageing and development\| PubMed ID: 11718814	2002
Protons at the gate: DEG/ENaC ion channels help us feel and remember. Neuron\| PubMed ID: 11988165	2002
Stochastic and genetic factors influence tissue-specific decline in ageing C. elegans. Nature\| PubMed ID: 12397350	2002
Specific aspartyl and calpain proteases are required for neurodegeneration in C. elegans. Nature\| PubMed ID: 12410314	2002
A potassium channel-MiRP complex controls neurosensory function in Caenorhabditis elegans. The Journal of biological chemistry\| PubMed ID: 12533541	2003
Dying for a cause: invertebrate genetics takes on human neurodegeneration. Nature reviews. Genetics\| PubMed ID: 12610523	2003
Modeling human peroxisome biogenesis disorders in the nematode Caenorhabditis elegans. Journal of cell science\| PubMed ID: 12665560	2003
In vivo imaging of C. elegans mechanosensory neurons demonstrates a specific role for the MEC-4 channel in the process of gentle touch sensation. Neuron\| PubMed ID: 12971899	2003
The neurotoxic MEC-4(d) DEG/ENaC sodium channel conducts calcium: implications for necrosis initiation. Nature neuroscience\| PubMed ID: 15543143	2004
In vivo spectrofluorimetry reveals endogenous biomarkers that report healthspan and dietary restriction in Caenorhabditis elegans. Aging cell\| PubMed ID: 15924569	2005
Temperature-sensitive mutant of the Caenorhabditis elegans neurotoxic MEC-4(d) DEG/ENaC channel identifies a site required for trafficking or surface maintenance. The Journal of biological chemistry\| PubMed ID: 16239217	2005
Modulated microRNA expression during adult lifespan in Caenorhabditis elegans. Aging cell\| PubMed ID: 16842496	2006
Caenorhabditis elegans glutamate transporters influence synaptic function and behavior at sites distant from the synapse. The Journal of biological chemistry\| PubMed ID: 17681948	2007
Culture of embryonic C. elegans cells for electrophysiological and pharmacological analyses. WormBook : the online review of C. elegans biology\| PubMed ID: 18050435	2006
Heterologous expression of C. elegans ion channels in Xenopus oocytes. WormBook : the online review of C. elegans biology\| PubMed ID: 18050441	2006
A role for autophagy in the extension of lifespan by dietary restriction in C. elegans. PLoS genetics\| PubMed ID: 18282106	2008
A novel computational approach for simultaneous tracking and feature extraction of C. elegans populations in fluid environments. IEEE transactions on bio-medical engineering\| PubMed ID: 18440900	2008
Sequence relationships among C. elegans, D. melanogaster and human microRNAs highlight the extensive conservation of microRNAs in biology. PloS one\| PubMed ID: 18665242	2008
A glial DEG/ENaC channel functions with neuronal channel DEG-1 to mediate specific sensory functions in C. elegans. The EMBO journal\| PubMed ID: 18701922	2008
Caenorhabditis elegans glutamate transporter deletion induces AMPA-receptor/adenylyl cyclase 9-dependent excitotoxicity. Journal of neurochemistry\| PubMed ID: 19054279	2009
FOXO3a is broadly neuroprotective in vitro and in vivo against insults implicated in motor neuron diseases. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 19553463	2009
MicroRNAs in C. elegans Aging: Molecular Insurance for Robustness? Current genomics\| PubMed ID: 19881908	2009
Metformin induces a dietary restriction-like state and the oxidative stress response to extend C. elegans Healthspan via AMPK, LKB1, and SKN-1. PloS one\| PubMed ID: 20090912	2010
Novel EGF pathway regulators modulate C. elegans healthspan and lifespan via EGF receptor, PLC-gamma, and IP3R activation. Aging cell\| PubMed ID: 20497132	2010
Specific roles for DEG/ENaC and TRP channels in touch and thermosensation in C. elegans nociceptors. Nature neuroscience\| PubMed ID: 20512132	2010
Spatial asymmetry in the mechanosensory phenotypes of the C. elegans DEG/ENaC gene mec-10. Journal of neurophysiology\| PubMed ID: 20881202	2010
EGF signaling comes of age: promotion of healthy aging in C. elegans. Experimental gerontology\| PubMed ID: 21074601	2011
The core apoptotic executioner proteins CED-3 and CED-4 promote initiation of neuronal regeneration in Caenorhabditis elegans. PLoS biology\| PubMed ID: 22629231	2012
Neurite sprouting and synapse deterioration in the aging Caenorhabditis elegans nervous system. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 22745480	2012
Complex expression dynamics and robustness in C. elegans insulin networks. Genome research\| PubMed ID: 23539137	2013
Dramatic fertility decline in aging C. elegans males is associated with mating execution deficits rather than diminished sperm quality. Experimental gerontology\| PubMed ID: 23916839	2013
Deletion of microRNA-80 activates dietary restriction to extend C. elegans healthspan and lifespan. PLoS genetics\| PubMed ID: 24009527	2013
Neuronal repair: Apoptotic proteins make good. Worm\| PubMed ID: 24058867	2013
NRA-2, a nicalin homolog, regulates neuronal death by controlling surface localization of toxic Caenorhabditis elegans DEG/ENaC channels. The Journal of biological chemistry\| PubMed ID: 24567339	2014
A novel MitoTimer reporter gene for mitochondrial content, structure, stress, and damage in vivo. The Journal of biological chemistry\| PubMed ID: 24644293	2014
Mechanism of longevity extension of Caenorhabditis elegans induced by pentagalloyl glucose isolated from eucalyptus leaves. Journal of agricultural and food chemistry\| PubMed ID: 24701969	2014
CeleST: computer vision software for quantitative analysis of C. elegans swim behavior reveals novel features of locomotion. PLoS computational biology\| PubMed ID: 25033081	2014
Insulin signaling in the aging of healthy and proteotoxically stressed mechanosensory neurons. Frontiers in genetics\| PubMed ID: 25101108	2014
Flow-scanning optical tomography. Lab on a chip\| PubMed ID: 25256716	2014
A lysine-rich motif in the phosphatidylserine receptor PSR-1 mediates recognition and removal of apoptotic cells. Nature communications\| PubMed ID: 25564762	2015
Using measures of single-cell physiology and physiological state to understand organismic aging. Aging cell\| PubMed ID: 26616110	2016
Age-Related Phasic Patterns of Mitochondrial Maintenance in Adult Caenorhabditis elegans Neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 26818523	2016
Morphological remodeling of C. elegans neurons during aging is modified by compromised protein homeostasis. NPJ aging and mechanisms of disease\| PubMed ID: 27347427	2016
Impact of genetic background and experimental reproducibility on identifying chemical compounds with robust longevity effects. Nature communications\| PubMed ID: 28220799	2017
A long journey to reproducible results. Nature\| PubMed ID: 28836615	2017
TOR-mediated regulation of metabolism in aging. Aging cell\| PubMed ID: 28971552	2017
Q&A: Trash talk: disposal and remote degradation of neuronal garbage. BMC biology\| PubMed ID: 29382333	2018
NemaFlex: a microfluidics-based technology for standardized measurement of muscular strength of C. elegans. Lab on a chip\| PubMed ID: 29892747	2018
Necrotic Neurodegeneration in Caenorhabditis Elegans. TheScientificWorldJournal\| PubMed ID: 30147608	2001
Execution of Necrotic-Like Cell Death in Requires Cathepsin D Activity. TheScientificWorldJournal\| PubMed ID: 30147617	2001
CED-4 CARD domain residues can modulate non-apoptotic neuronal regeneration functions independently from apoptosis. Scientific reports\| PubMed ID: 31527664	2019
Automated lifespan determination across Caenorhabditis strains and species reveals assay-specific effects of chemical interventions. GeroScience\| PubMed ID: 31820364	2019
Intervention Testing Program: the creatine analog β-guanidinopropionic acid does not extend lifespan in nematodes. microPublication biology\| PubMed ID: 31998863	2020
Intervention Testing Program: the tyrosine kinase inhibitor imatinib mesylate does not extend lifespan in nematodes. microPublication biology\| PubMed ID: 32010883	2019
Healthy lifespan extension mediated by oenothein B isolated from Eucalyptus grandis × Eucalyptus urophylla GL9 in Caenorhabditis elegans. Food & function\| PubMed ID: 32129349	2020
Intervention Testing Program: the farnesoid X receptor agonist obeticholic acid does not robustly extend lifespan in nematodes. microPublication biology\| PubMed ID: 32550518	2020
Gluconeogenesis and PEPCK are critical components of healthy aging and dietary restriction life extension. PLoS genetics\| PubMed ID: 32841230	2020