Michael V. Sefton

Institute of Biomaterials and Biomedical Engineering / Department of Chemical Engineering and Applied Chemistry, University of Toronto

Affiliated withUniversity of Toronto

Research Area

Bioengineering

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 9	2010

Other Publications

Article	Year
Functional considerations in tissue-engineering whole organs. Annals of the New York Academy of Sciences\| PubMed ID: 12081898	2002
Functional assessment of engineered tissues and elements of tissue design: breakout session summary. Annals of the New York Academy of Sciences\| PubMed ID: 12081902	2002
Reaction of poly(acrylamide-co-vinylamine) with tresyl-PEG in the presence of PC12 cells. Biomaterials\| PubMed ID: 12423598	2003
Biomaterial-associated thrombosis: roles of coagulation factors, complement, platelets and leukocytes. Biomaterials\| PubMed ID: 15147815	2004
Poly(methylidene malonate 2.1.2) nanoparticles: a biocompatible polymer that enhances peri-adventitial adenoviral gene delivery. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 15313000	2004
Expression of matrix metalloproteinase-2 and -9 in exudates associated with polydimethyl siloxane and gelatin tubes implanted in mice. Journal of biomedical materials research. Part A\| PubMed ID: 15386490	2004
In vivo recognition by the host adaptive immune system of microencapsulated xenogeneic cells. Transplantation\| PubMed ID: 15599309	2004
Endotoxin: the uninvited guest. Biomaterials\| PubMed ID: 16019062	2005
Semi-synthetic collagen/poloxamine matrices for tissue engineering. Biomaterials\| PubMed ID: 16023714	2005
Poloxamine hydrogels with a quaternary ammonium modification to improve cell attachment. Journal of biomedical materials research. Part A\| PubMed ID: 16059894	2005
Surface study of collagen/poloxamine hydrogels by a 'deep freezing' ToF-SIMS approach. Biomaterials\| PubMed ID: 16332388	2006
Methylation of poloxamine for enhanced cell adhesion. Biomacromolecules\| PubMed ID: 16398533	2006
Conformal coating of mammalian cells immobilized onto magnetically driven beads. Tissue engineering\| PubMed ID: 16411825	2005
Collagen/poloxamine hydrogels: cytocompatibility of embedded HepG2 cells and surface-attached endothelial cells. Tissue engineering\| PubMed ID: 16411826	2005
Vascularized organoid engineered by modular assembly enables blood perfusion. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16864785	2006
Suppressed splenocyte proliferation following a xenogeneic skin graft due to implanted biomaterials. Transplantation\| PubMed ID: 16906042	2006
Tissue factor and thrombomodulin expression on endothelial cell-seeded collagen modules for tissue engineering. Journal of biomedical materials research. Part A\| PubMed ID: 17111414	2007
The influence of biomaterials on endothelial cell thrombogenicity. Biomaterials\| PubMed ID: 17316788	2007
Fabrication of cell-containing gel modules to assemble modular tissue-engineered constructs [corrected]. Nature protocols\| PubMed ID: 17406556	2006
Design criteria for a modular tissue-engineered construct. Tissue engineering\| PubMed ID: 17439395	2007
Advanced tools for tissue engineering: scaffolds, bioreactors, and signaling. Tissue engineering\| PubMed ID: 17518670	2006
Vascularization and improved in vivo survival of VEGF-secreting cells microencapsulated in HEMA-MMA. Tissue engineering\| PubMed ID: 17523877	2007
Poly(butyl methacrylate-co-methacrylic acid) tissue engineering scaffold with pro-angiogenic potential in vivo. Journal of biomedical materials research. Part A\| PubMed ID: 17530634	2007
Design and fabrication of sub-mm-sized modules containing encapsulated cells for modular tissue engineering. Tissue engineering\| PubMed ID: 17582838	2007
A modular tissue engineering construct containing smooth muscle cells and endothelial cells. Annals of biomedical engineering\| PubMed ID: 17882548	2007
Lactoyl-poloxamine/collagen matrix for cell-containing tissue engineering modules. Journal of biomedical materials research. Part A\| PubMed ID: 17969022	2008
Modular tissue engineering: fabrication of a gelatin-based construct. Journal of tissue engineering and regenerative medicine\| PubMed ID: 18038402	2007
Effect of mouse VEGF164 on the viability of hydroxyethyl methacrylate-methyl methacrylate-microencapsulated cells in vivo: bioluminescence imaging. Journal of biomedical materials research. Part A\| PubMed ID: 18181105	2008
Innate and adaptive immune responses in tissue engineering. Seminars in immunology\| PubMed ID: 18221888	2008
The thrombogenicity of human umbilical vein endothelial cell seeded collagen modules. Biomaterials\| PubMed ID: 18325586	2008
Amidine surface modification of poly(acrylonitrile-co-vinyl chloride) reduces platelet adhesion. Journal of biomedical materials research. Part A\| PubMed ID: 18465816	2009
IL-10 secretion increases signal persistence of HEMA-MMA-microencapsulated luciferase-modified CHO fibroblasts in mice. Tissue engineering. Part A\| PubMed ID: 18710337	2009
Acceleration of diabetic wound healing by an angiopoietin peptide mimetic. Tissue engineering. Part A\| PubMed ID: 18939935	2009
A preliminary study of the effect of poly(methacrylic acid-co-methyl methacrylate) beads on angiogenesis in rodent skin grafts and the quality of the panniculus carnosus. Plastic and reconstructive surgery\| PubMed ID: 18971719	2008
Dual delivery of placental growth factor and vascular endothelial growth factor from poly(hydroxyethyl methacrylate-co-methyl methacrylate) microcapsules containing doubly transfected lucife... Tissue engineering. Part A\| PubMed ID: 19125649	2009
The effect of a hydroxamic acid-containing polymer on active matrix metalloproteinases. Biomaterials\| PubMed ID: 19147221	2009
Fate of endothelialized modular constructs implanted in an omental pouch in nude rats. Tissue engineering. Part A\| PubMed ID: 19265460	2009
Effect of a matrix metalloproteinase sequestering biomaterial on Caco-2 epithelial cell barrier integrity in vitro. Acta biomaterialia\| PubMed ID: 19307161	2009
Poly(methacrylic acid-co-methyl methacrylate) beads promote vascularization and wound repair in diabetic mice. Journal of biomedical materials research. Part A\| PubMed ID: 19585566	2010
MMP levels in the response to degradable implants in the presence of a hydroxamate-based matrix metalloproteinase sequestering biomaterial in vivo. Journal of biomedical materials research. Part A\| PubMed ID: 19911383	2010
A modular approach to cardiac tissue engineering. Tissue engineering. Part A\| PubMed ID: 20504074	2010
Effectiveness factor and diffusion limitations in collagen gel modules containing HepG2 cells. Journal of tissue engineering and regenerative medicine\| PubMed ID: 20653045	2011
Perfusion and characterization of an endothelial cell-seeded modular tissue engineered construct formed in a microfluidic remodeling chamber. Biomaterials\| PubMed ID: 20678792	2010
Chimeric vessel tissue engineering driven by endothelialized modules in immunosuppressed Sprague-Dawley rats. Tissue engineering. Part A\| PubMed ID: 20695789	2011
Endothelial cell behaviour within a microfluidic mimic of the flow channels of a modular tissue engineered construct. Biomedical microdevices\| PubMed ID: 20842530	2011
Patterning Collagen/Poloxamine-Methacrylate Hydrogels for Tissue-Engineering-Inspired Microfluidic and Laser Lithography Applications. Journal of biomaterials science. Polymer edition\| PubMed ID: 21144168	2010
A Poloxamine-Polylysine Acrylate Scaffold for Modular Tissue Engineering. Journal of biomaterials science. Polymer edition\| PubMed ID: 21144169	2010
Application of an endothelialized modular construct for islet transplantation in syngeneic and allogeneic immunosuppressed rat models. Tissue engineering. Part A\| PubMed ID: 21449709	2011
Endothelialized biomaterials for tissue engineering applications in vivo. Trends in biotechnology\| PubMed ID: 21549438	2011
Bone marrow-derived mesenchymal stromal cells enhance chimeric vessel development driven by endothelial cell-coated microtissues. Tissue engineering. Part A\| PubMed ID: 21861779	2012
On the mechanism of poly(methacrylic acid -co- methyl methacrylate)-induced angiogenesis: gene expression analysis of dTHP-1 cells. Biomaterials\| PubMed ID: 21872324	2011
Toward an In Vitro Vasculature: Differentiation of Mesenchymal Stromal Cells Within an Endothelial Cell-Seeded Modular Construct in a Microfluidic Flow Chamber. Tissue engineering. Part A\| PubMed ID: 21992078	2011
Recovery of cardiac function mediated by MSC and interleukin-10 plasmid functionalised scaffold. Biomaterials\| PubMed ID: 22078809	2012