Pedro Cabrales

Bioengineering, University of California, San Diego

Affiliated withUniversity of California, San Diego

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 36	2010

Other Publications

Article	Year
Microvascular oxygen distribution in awake hamster window chamber model during hyperoxia. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 12805029	2003
Measurement of the cardiac output in small animals by thermodilution. Microvascular research\| PubMed ID: 12935765	2003
Microcirculatory changes during chronic adaptation to hypoxia. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 14561680	2003
Radial displacement of red blood cells during hemodilution and the effect on arteriolar oxygen profile. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 14615279	2004
Microlymphatic and tissue oxygen tension in the rat mesentery. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 14630627	2004
Microvascular pressure and functional capillary density in extreme hemodilution with low- and high-viscosity dextran and a low-viscosity Hb-based O2 carrier. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 14975932	2004
Microvascular PO2 during extreme hemodilution with hemoglobin site specifically PEGylated at Cys-93(beta) in hamster window chamber. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 15191899	2004
Oxygen delivery and consumption in the microcirculation after extreme hemodilution with perfluorocarbons. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 15210452	2004
Oxygen-carrying blood substitutes: a microvascular perspective. Expert opinion on biological therapy\| PubMed ID: 15268681	2004
Increased tissue PO2 and decreased O2 delivery and consumption after 80% exchange transfusion with polymerized hemoglobin. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 15297257	2004
Resuscitation from hemorrhagic shock with MalPEG-albumin: comparison with MalPEG-hemoglobin. Shock (Augusta, Ga.)\| PubMed ID: 15377891	2004
Hyperosmotic-hyperoncotic versus hyperosmotic-hyperviscous: small volume resuscitation in hemorrhagic shock. Shock (Augusta, Ga.)\| PubMed ID: 15489635	2004
Microvascular perfusion upon exchange transfusion with stored red blood cells in normovolemic anemic conditions. Transfusion\| PubMed ID: 15504169	2004
Oxygen distribution and respiration by the microcirculation. Antioxidants & redox signaling\| PubMed ID: 15548898	2004
Oxygen transport by low and normal oxygen affinity hemoglobin vesicles in extreme hemodilution. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 15563528	2005
Microvascular oxygen delivery and consumption following treatment with verapamil. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 15563532	2005
Elevated plasma viscosity in extreme hemodilution increases perivascular nitric oxide concentration and microvascular perfusion. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 15576432	2005
Alginate plasma expander maintains perfusion and plasma viscosity during extreme hemodilution. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 15591096	2005
Effects of extreme hemodilution with hemoglobin-based O2 carriers on microvascular pressure. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 15637119	2005
Oxygen release from low and normal P50 Hb vesicles in transiently occluded arterioles of the hamster window model. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 15681705	2005
Increase plasma viscosity sustains microcirculation after resuscitation from hemorrhagic shock and continuous bleeding. Shock (Augusta, Ga.)\| PubMed ID: 15897809	2005
Early difference in tissue pH and microvascular hemodynamics in hemorrhagic shock resuscitation using polyethylene glycol-albumin- and hydroxyethyl starch-based plasma expanders. Shock (Augusta, Ga.)\| PubMed ID: 15988323	2005
Blood viscosity: a factor in tissue survival? Critical care medicine\| PubMed ID: 16003089	2005
Extreme hemodilution with PEG-hemoglobin vs. PEG-albumin. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 16024576	2005
Effect of oxygen consumption by measuring method on PO2 transients associated with the passage of erythrocytes in capillaries of rat mesentery. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 16162870	2005
Role of endothelial nitric oxide in microvascular oxygen delivery and consumption. Free radical biology & medicine\| PubMed ID: 16214038	2005
The vascular wall as a regulator of tissue oxygenation. Current opinion in nephrology and hypertension\| PubMed ID: 16340669	2006
Nitric oxide regulation of microvascular oxygen exchange during hypoxia and hyperoxia. Journal of applied physiology (Bethesda, Md. : 1985)\| PubMed ID: 16357070	2006
Microvascular effects following treatment with polyethylene glycol-albumin in lipopolysaccharide-induced endotoxemia. Critical care medicine\| PubMed ID: 16374164	2006
Oxygen release from arterioles with normal flow and no-flow conditions. Journal of applied physiology (Bethesda, Md. : 1985)\| PubMed ID: 16384838	2006
Increased cardiac output and microvascular blood flow during mild hemoconcentration in hamster window model. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 16489106	2006
Blood viscosity maintains microvascular conditions during normovolemic anemia independent of blood oxygen-carrying capacity. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 16517943	2006
Can the effects of vasoactivity of molecular hemoglobin-based plasma expanders be ignored? Critical care medicine\| PubMed ID: 16633264	2006
Plasma viscosity regulates systemic and microvascular perfusion during acute extreme anemic conditions. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 16731641	2006
Microvascular perspective of oxygen-carrying and -noncarrying blood substitutes. Annual review of biomedical engineering\| PubMed ID: 16834558	2006
Dissociation of local nitric oxide concentration and vasoconstriction in the presence of cell-free hemoglobin oxygen carriers. Blood\| PubMed ID: 16857991	2006
Hemorrhagic shock resuscitation with carbon monoxide saturated blood. Resuscitation\| PubMed ID: 17092627	2007
Deferoxamine lowers tissue damage after 80% exchange transfusion with polymerized hemoglobin. Antioxidants & redox signaling\| PubMed ID: 17184174	2007
Perfluorocarbon in microcirculation during ischemia reperfusion. Journal of the American College of Surgeons\| PubMed ID: 17254926	2007
Microvascular and systemic effects following top load administration of saturated carbon monoxide-saline solution. Critical care medicine\| PubMed ID: 17334240	2007
Microvascular and capillary perfusion following glycocalyx degradation. Journal of applied physiology (Bethesda, Md. : 1985)\| PubMed ID: 17347383	2007
Excessive erythrocytosis does not elevate capillary oxygen delivery in subcutaneous mouse tissue. Microcirculation (New York, N.Y. : 1994)\| PubMed ID: 17365666	2007
Is resuscitation from hemorrhagic shock limited by blood oxygen-carrying capacity or blood viscosity? Shock (Augusta, Ga.)\| PubMed ID: 17414420	2007
Effects of erythrocyte flexibility on microvascular perfusion and oxygenation during acute anemia. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 17449555	2007
Transfusion restores blood viscosity and reinstates microvascular conditions from hemorrhagic shock independent of oxygen carrying capacity. Resuscitation\| PubMed ID: 17481796	2007
New phosphorescence quenching oxygen measurements technique yields unusual tissue and plasma PO2 distributions. Journal of applied physiology (Bethesda, Md. : 1985)\| PubMed ID: 17483445	2007
Time-dependant oxygen partial pressure in capillaries and tissue in the hamster window chamber model. Antioxidants & redox signaling\| PubMed ID: 17508910	2007
Resuscitation from hemorrhagic shock with hydroxyethyl starch and coagulation changes. Shock (Augusta, Ga.)\| PubMed ID: 17558350	2007
Lowering of blood pressure by increasing hematocrit with non nitric oxide scavenging red blood cells. American journal of respiratory cell and molecular biology\| PubMed ID: 17709601	2008
Modulation of perfusion and oxygenation by red blood cell oxygen affinity during acute anemia. American journal of respiratory cell and molecular biology\| PubMed ID: 17884988	2008
Terminal lymphatics: the potential "lethal corner" in the distribution of tissue pO2. Lymphatic research and biology\| PubMed ID: 18035934	2007
Increased hematocrit and reduced blood pressure following control of glycemia in diabetes. Clinical hemorheology and microcirculation\| PubMed ID: 18094460	2008
Increased plasma viscosity prolongs microhemodynamic conditions during small volume resuscitation from hemorrhagic shock. Resuscitation\| PubMed ID: 18308459	2008
Survival time in severe hemorrhagic shock after perioperative hemodilution is longer with PEG-conjugated human serum albumin than with HES 130/0.4: a microvascular perspective. Critical care (London, England)\| PubMed ID: 18423033	2008
Microvascular experimental evidence on the relative significance of restoring oxygen carrying capacity vs. blood viscosity in shock resuscitation. Biochimica et biophysica acta\| PubMed ID: 18502215	2008
Oxygen transport during hemodilution with a perfluorocarbon-based oxygen carrier: effect of altitude and hyperoxia. Journal of applied physiology (Bethesda, Md. : 1985)\| PubMed ID: 18535127	2008
Volume resuscitation from hemorrhagic shock with albumin and hexaPEGylated human serum albumin. Resuscitation\| PubMed ID: 18621463	2008
Balance between vasoconstriction and enhanced oxygen delivery. Transfusion\| PubMed ID: 18631171	2008
Polymerized bovine hemoglobin can improve small-volume resuscitation from hemorrhagic shock in hamsters. Shock (Augusta, Ga.)\| PubMed ID: 18636045	2009
Isovolemic exchange transfusion with increasing concentrations of low oxygen affinity hemoglobin solution limits oxygen delivery due to vasoconstriction. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 18835914	2008
Microcirculatory effects of changing blood hemoglobin oxygen affinity during hemorrhagic shock resuscitation in an experimental model. Shock (Augusta, Ga.)\| PubMed ID: 18948853	2009
Blood pressure reduction due to hemoglobin glycosylation in type 2 diabetic patients. Vascular health and risk management\| PubMed ID: 19066010	2008
Exogenous nitric oxide induces protection during hemorrhagic shock. Resuscitation\| PubMed ID: 19362408	2009
Nonobese, exercising children diagnosed with dyslipidemia have normal C-reactive protein. Vascular health and risk management\| PubMed ID: 19436676	2009
Will fixing the vasoactivity caused by hemoglobin-based oxygen carriers be enough? Critical care medicine\| PubMed ID: 19448469	2009
Hematocrit and mean arterial blood pressure in pre- and postmenopause women. Vascular health and risk management\| PubMed ID: 19554088	2009
Hexa-thiocarbamoyl phenyl PEG5K Hb: vasoactivity and structure: influence of rigidity of the conjugation linkage on the PEGylation induced plasma expander-like solution properties of PEG-Hb ... The protein journal\| PubMed ID: 19653083	2009
Effects of the molecular mass of tense-state polymerized bovine hemoglobin on blood pressure and vasoconstriction. Journal of applied physiology (Bethesda, Md. : 1985)\| PubMed ID: 19745190	2009
The physics of oxygen delivery: facts and controversies. Antioxidants & redox signaling\| PubMed ID: 19757988	2010
Low dose nitrite enhances perfusion after fluid resuscitation from hemorrhagic shock. Resuscitation\| PubMed ID: 19804938	2009
Nitrate and nitrite in biology, nutrition and therapeutics. Nature chemical biology\| PubMed ID: 19915529	2009
Tissue oxygenation after exchange transfusion with ultrahigh-molecular-weight tense- and relaxed-state polymerized bovine hemoglobins. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 20061539	2010
Murine cerebral malaria is associated with a vasospasm-like microcirculatory dysfunction, and survival upon rescue treatment is markedly increased by nimodipine. The American journal of pathology\| PubMed ID: 20110412	2010
Blood pressure directly correlates with blood viscosity in diabetes type 1 children but not in normals. Clinical hemorheology and microcirculation\| PubMed ID: 20134093	2010
Synthesis, biophysical properties and pharmacokinetics of ultrahigh molecular weight tense and relaxed state polymerized bovine hemoglobins. Biomaterials\| PubMed ID: 20149433	2010
Low oxygen-affinity hemoglobin solution increases oxygenation of partially ischemic tissue during acute anemia. Journal of the American College of Surgeons\| PubMed ID: 20193889	2010
Sustained release nitric oxide from long-lived circulating nanoparticles. Free radical biology & medicine\| PubMed ID: 20460149	2010
The variability of blood pressure due to small changes of hematocrit. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 20601464	2010
Perfusion vs. oxygen delivery in transfusion with "fresh" and "old" red blood cells: the experimental evidence. Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis\| PubMed ID: 20646963	2010
Cardiac systolic function recovery after hemorrhage determines survivability during shock. The Journal of trauma\| PubMed ID: 20805773	2011
Tissue oxidative metabolism after extreme hemodilution with PEG-conjugated hemoglobin. Journal of applied physiology (Bethesda, Md. : 1985)\| PubMed ID: 20813980	2010
Effects of plasma viscosity modulation on cardiac function during moderate hemodilution. Asian journal of transfusion science\| PubMed ID: 20859509	2010
Biophysical properties and oxygenation potential of high-molecular-weight glutaraldehyde-polymerized human hemoglobins maintained in the tense and relaxed quaternary states. Tissue engineering. Part A\| PubMed ID: 20979534	2011
Reversal of hemoglobin-induced vasoconstriction with sustained release of nitric oxide. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 21057038	2011
Cardiac mechanoenergetic cost of elevated plasma viscosity after moderate hemodilution. Biorheology\| PubMed ID: 21084746	2010
Synthesis and biophysical properties of polymerized human serum albumin. Biotechnology progress\| PubMed ID: 21213297	2010
Improved resuscitation from hemorrhagic shock with Ringer's lactate with increased viscosity in the hamster window chamber model. The Journal of trauma\| PubMed ID: 21248647	2011
Synthesis and biophysical properties of polymerized human serum albumin. Biotechnology progress\| PubMed ID: 21312376	2011
Delaying blood transfusion in experimental acute anemia with a perfluorocarbon emulsion. Anesthesiology\| PubMed ID: 21326091	2011
Small-volume resuscitation from hemorrhagic shock using high-molecular-weight tense-state polymerized hemoglobins. The Journal of trauma\| PubMed ID: 21336190	2011
Exogenous nitric oxide prevents cardiovascular collapse during hemorrhagic shock. Resuscitation\| PubMed ID: 21342744	2011
Nitric oxide protection against murine cerebral malaria is associated with improved cerebral microcirculatory physiology. The Journal of infectious diseases\| PubMed ID: 21415018	2011
Integration of cardiovascular regulation by the blood/endothelium cell-free layer. Wiley interdisciplinary reviews. Systems biology and medicine\| PubMed ID: 21523919	2011
Synthesis, biophysical properties, and oxygenation potential of variable molecular weight glutaraldehyde-polymerized bovine hemoglobins with low and high oxygen affinity. Biotechnology progress\| PubMed ID: 21584950	2011
Exogenous nitric oxide decreases brain vascular inflammation, leakage and venular resistance during Plasmodium berghei ANKA infection in mice. Journal of neuroinflammation\| PubMed ID: 21649904	2011
Nanoengineering bactericidal nitric oxide therapies. Virulence\| PubMed ID: 21670586	2011
Exogenous intravascular nitric oxide enhances ventricular function after hemodilution with plasma expander. Life sciences\| PubMed ID: 22056371	2012
Small-volume resuscitation from hemorrhagic shock with polymerized human serum albumin. The American journal of emergency medicine\| PubMed ID: 22100469	2011
Nonlinear cardiovascular regulation consequent to changes in blood viscosity. Clinical hemorheology and microcirculation\| PubMed ID: 22214675	2011
Effects of acute anemia and hyperoxia on oxygen distribution. Advances in experimental medicine and biology\| PubMed ID: 22259104	2012
Simulation of NO and O(2) transport facilitated by polymerized hemoglobin solutions in an arteriole that takes into account wall shear stress-induced NO production. Biophysical chemistry\| PubMed ID: 22285312	2012
Hypervolemic infusion of Lumbricus terrestris erythrocruorin purified by tangential-flow filtration. Transfusion\| PubMed ID: 22304397	2012