Alexander Yu. Nikitin

Department of Biomedical Sciences, Cornell University

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 7	2016

Other Publications

Article	Year
Cell lineage-specific effects associated with multiple deficiencies of tumor susceptibility genes in Msh2(-/-)Rb(+/-) mice. Cancer research\| PubMed ID: 12234974	2002
ARF mutation accelerates pituitary tumor development in Rb+/- mice. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12486224	2002
Minimal effects of dietary restriction on neuroendocrine carcinogenesis in Rb+/- mice. Carcinogenesis\| PubMed ID: 12584165	2003
Female mice chimeric for expression of the simian virus 40 TAg under control of the MISIIR promoter develop epithelial ovarian cancer. Cancer research\| PubMed ID: 12649204	2003
Live tissue intrinsic emission microscopy using multiphoton-excited native fluorescence and second harmonic generation. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12756303	2003
Induction of carcinogenesis by concurrent inactivation of p53 and Rb1 in the mouse ovarian surface epithelium. Cancer research\| PubMed ID: 12839925	2003
Mammary carcinoma suppression by cellular retinoic acid binding protein-II. Cancer research\| PubMed ID: 12907615	2003
Classification of proliferative pulmonary lesions of the mouse: recommendations of the mouse models of human cancers consortium. Cancer research\| PubMed ID: 15059877	2004
Somatic mutation of p53 leads to estrogen receptor alpha-positive and -negative mouse mammary tumors with high frequency of metastasis. Cancer research\| PubMed ID: 15150107	2004
Use of multiphoton imaging for studying cell migration in the mouse. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 15576922	2005
Suppression of melanotroph carcinogenesis leads to accelerated progression of pituitary anterior lobe tumors and medullary thyroid carcinomas in Rb+/- mice. Cancer research\| PubMed ID: 15705875	2005
Cyclooxygenase-1 is overexpressed in multiple genetically engineered mouse models of epithelial ovarian cancer. Cancer research\| PubMed ID: 16510568	2006
Synergy of p53 and Rb deficiency in a conditional mouse model for metastatic prostate cancer. Cancer research\| PubMed ID: 16912162	2006
Precancer in mice: animal models used to understand, prevent, and treat human precancers. Toxicologic pathology\| PubMed ID: 17074738	2006
Training mouse pathologists: five years of pathology of mouse models of human disease workshops. Toxicologic pathology\| PubMed ID: 17474065	2007
Prostate cancer associated with p53 and Rb deficiency arises from the stem/progenitor cell-enriched proximal region of prostatic ducts. Cancer research\| PubMed ID: 17553900	2007
From whence will they come? - A perspective on the acute shortage of pathologists in biomedical research. Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc\| PubMed ID: 17609364	2007
Mouse models of prostate adenocarcinoma with the capacity to monitor spontaneous carcinogenesis by bioluminescence or fluorescence. Cancer research\| PubMed ID: 17671224	2007
MicroRNA-34b and MicroRNA-34c are targets of p53 and cooperate in control of cell proliferation and adhesion-independent growth. Cancer research\| PubMed ID: 17823410	2007
Cell lineage-specific interactions between Men1 and Rb in neuroendocrine neoplasia. Carcinogenesis\| PubMed ID: 17893233	2008
Toxicity and biomedical imaging of layered nanohybrids in the mouse. Toxicologic pathology\| PubMed ID: 17943654	2007
Broad overexpression of ribonucleotide reductase genes in mice specifically induces lung neoplasms. Cancer research\| PubMed ID: 18413732	2008
Disruption of the circadian clock due to the Clock mutation has discrete effects on aging and carcinogenesis. Cell cycle (Georgetown, Tex.)\| PubMed ID: 18418054	2008
Pro-neural transcription factors as cancer markers. BMC medical genomics\| PubMed ID: 18489756	2008
Overcoming retinoic acid-resistance of mammary carcinomas by diverting retinoic acid from PPARbeta/delta to RAR. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18495924	2008
Role of p53 and Rb in ovarian cancer. Advances in experimental medicine and biology\| PubMed ID: 18546622	2008
MicroRNA and ovarian cancer. Histology and histopathology\| PubMed ID: 18581287	2008
Do-it-yourself (DIY) pathology. Nature biotechnology\| PubMed ID: 18779800	2008
Mouse models for cancer stem cell research. Toxicologic pathology\| PubMed ID: 19920280	2010
EGF potentiated oncogenesis requires a tissue transglutaminase-dependent signaling pathway leading to Src activation. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 20080707	2010
Frequent downregulation of miR-34 family in human ovarian cancers. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 20145172	2010
Strategies for high-resolution imaging of epithelial ovarian cancer by laparoscopic nonlinear microscopy. Translational oncology\| PubMed ID: 20563260	2010
Mouse prostate cancer cell lines established from primary and postcastration recurrent tumors. Hormones & cancer\| PubMed ID: 20631921	2010
Local mesenchymal stem/progenitor cells are a preferential target for initiation of adult soft tissue sarcomas associated with p53 and Rb deficiency. The American journal of pathology\| PubMed ID: 20864684	2010
Advancing translational research. Science (New York, N.Y.)\| PubMed ID: 21436422	2011
Dominant activation of the hedgehog signaling pathway alters development of the female reproductive tract. Genesis (New York, N.Y. : 2000)\| PubMed ID: 21809434	2012
Wild-type p53 controls cell motility and invasion by dual regulation of MET expression. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 21831840	2011
MET-dependent cancer invasion may be preprogrammed by early alterations of p53-regulated feedforward loop and triggered by stromal cell-derived HGF. Cell cycle (Georgetown, Tex.)\| PubMed ID: 22071625	2011
Training mouse pathologists: ten years of workshops on the Pathology of Mouse Models of Human Disease. Toxicologic pathology\| PubMed ID: 22421749	2012
Challenges in pre-clinical testing of anti-cancer drugs in cell culture and in animal models. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 22446384	2012
Implanted adipose progenitor cells as physicochemical regulators of breast cancer. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 22665775	2012
c-kit+ precursors support postinfarction myogenesis in the neonatal, but not adult, heart. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 22847442	2012
Ovarian surface epithelium at the junction area contains a cancer-prone stem cell niche. Nature\| PubMed ID: 23467088	2013
Effects of Jianpi Jiedu Recipe on reversion of P-glycoprotein-mediated multidrug resistance through COX-2 pathway in colorectal cancer. Chinese journal of integrative medicine\| PubMed ID: 23543356	2014
Detection and organ-specific ablation of neuroendocrine cells by synaptophysin locus-based BAC cassette in transgenic mice. PloS one\| PubMed ID: 23630575	2013
Loss of survivin in the prostate epithelium impedes carcinogenesis in a mouse model of prostate adenocarcinoma. PloS one\| PubMed ID: 23936028	2013
PTEN is a potent suppressor of small cell lung cancer. Molecular cancer research : MCR\| PubMed ID: 24482365	2014
miR-34 cooperates with p53 in suppression of prostate cancer by joint regulation of stem cell compartment. Cell reports\| PubMed ID: 24630988	2014
The Thoc1 ribonucleoprotein and prostate cancer progression. Journal of the National Cancer Institute\| PubMed ID: 25296641	2014
A Quest for Better Mouse Models of Breast and Ovarian Cancers. EBioMedicine\| PubMed ID: 26629501	2015
Role of the stem cell niche in the pathogenesis of epithelial ovarian cancers. Molecular & cellular oncology\| PubMed ID: 27308341	2014