Nicolas Schlegel

Department of General, University of Würzburg

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2022

Other Publications

Article	Year
Lipopolysaccharide-induced endothelial barrier breakdown is cyclic adenosine monophosphate dependent in vivo and in vitro. Critical care medicine\| PubMed ID: 19325485	2009
Impaired integrin-mediated adhesion contributes to reduced barrier properties in VASP-deficient microvascular endothelium. Journal of cellular physiology\| PubMed ID: 19347869	2009
Endothelial barrier stabilization by a cyclic tandem peptide targeting VE-cadherin transinteraction in vitro and in vivo. Journal of cell science\| PubMed ID: 19420236	2009
Impaired cAMP and Rac 1 signaling contribute to TNF-alpha-induced endothelial barrier breakdown in microvascular endothelium. Microcirculation (New York, N.Y. : 1994)\| PubMed ID: 19504398	2009
The impact of crystalloid and colloid infusion on the kidney in rodent sepsis. Intensive care medicine\| PubMed ID: 19890625	2010
Desmoglein 2-mediated adhesion is required for intestinal epithelial barrier integrity. American journal of physiology. Gastrointestinal and liver physiology\| PubMed ID: 20224006	2010
Differential role of Rho GTPases in intestinal epithelial barrier regulation in vitro. Journal of cellular physiology\| PubMed ID: 20945370	2011
Pulmonary effects of positive end-expiratory pressure and fluid therapy in experimental lung injury. Experimental lung research\| PubMed ID: 21077780	2011
Atrial natriuretic peptide enhances microvascular albumin permeability by the caveolae-mediated transcellular pathway. Cardiovascular research\| PubMed ID: 22025581	2012
Phosphodiesterase-4 inhibition as a therapeutic approach to treat capillary leakage in systemic inflammation. The Journal of physiology\| PubMed ID: 22495586	2012
Role of NF-κB activation in LPS-induced endothelial barrier breakdown. Histochemistry and cell biology\| PubMed ID: 22718247	2012
Effects of crystalloids and colloids on liver and intestine microcirculation and function in cecal ligation and puncture induced septic rodents. BMC gastroenterology\| PubMed ID: 23245375	2012
Phosphodiesterase 4 inhibition dose dependently stabilizes microvascular barrier functions and microcirculation in a rodent model of polymicrobial sepsis. Shock (Augusta, Ga.)\| PubMed ID: 24569506	2014
[Is a different view on the pathophysiology of sepsis the key for novel therapeutic options?]. Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen\| PubMed ID: 25103839	2014
E7080 (lenvatinib), a multi-targeted tyrosine kinase inhibitor, demonstrates antitumor activities against colorectal cancer xenografts. Neoplasia (New York, N.Y.)\| PubMed ID: 25425971	2014
Phosphodiesterase-4 inhibition with rolipram attenuates hepatocellular injury in hyperinflammation in vivo and in vitro without influencing inflammation and HO-1 expression. Journal of pharmacology & pharmacotherapeutics\| PubMed ID: 25709347	2015
Sphincter-sparing intersphincteric rectal resection as an alternative to proctectomy in long-standing fistulizing and stenotic Crohn's proctitis? International journal of colorectal disease\| PubMed ID: 25847822	2015
Soluble VE-cadherin is involved in endothelial barrier breakdown in systemic inflammation and sepsis. Cardiovascular research\| PubMed ID: 25975259	2015
Sepsis-induced acute kidney injury by standardized colon ascendens stent peritonitis in rats - a simple, reproducible animal model. Intensive care medicine experimental\| PubMed ID: 26266931	2014
Glial cell line-derived neurotrophic factor promotes barrier maturation and wound healing in intestinal epithelial cells in vitro. American journal of physiology. Gastrointestinal and liver physiology\| PubMed ID: 26294673	2015
Balanced Hydroxyethylstarch (HES 130/0.4) Impairs Kidney Function In-Vivo without Inflammation. PloS one\| PubMed ID: 26340751	2015
The glial cell-line derived neurotrophic factor: a novel regulator of intestinal barrier function in health and disease. American journal of physiology. Gastrointestinal and liver physiology\| PubMed ID: 27151942	2016
[Updated definition of sepsis : Implications for diagnostics and therapy principles]. Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen\| PubMed ID: 27975124	2017
Sphingosine-1-Phosphate Receptor-1 Agonist Sew2871 Causes Severe Cardiac Side Effects and Does Not Improve Microvascular Barrier Breakdown in Sepsis. Shock (Augusta, Ga.)\| PubMed ID: 28538086	2018
[Expectations of visceral surgeons from the results of clinical autopsies]. Der Pathologe\| PubMed ID: 28660345	2017
Dsg2 via Src-mediated transactivation shapes EGFR signaling towards cell adhesion. Cellular and molecular life sciences : CMLS\| PubMed ID: 29980799	2018
Desmoglein 2, but not desmocollin 2, protects intestinal epithelia from injury. Mucosal immunology\| PubMed ID: 30115995	2018
Ureaplasma species modulate cell adhesion molecules and growth factors in human brain microvascular endothelial cells. Cytokine\| PubMed ID: 31158700	2019
Correction to: Dsg2 via Src-mediated transactivation shapes EGFR signaling towards cell adhesion. Cellular and molecular life sciences : CMLS\| PubMed ID: 31292664	2019
Prognostic Relevance of Steroid Sulfation in Adrenocortical Carcinoma Revealed by Molecular Phenotyping Using High-Resolution Mass Spectrometry Imaging. Clinical chemistry\| PubMed ID: 31492715	2019
Mortality and Complications Following Visceral Surgery: A Nationwide Analysis Based on the Diagnostic Categories Used in German Hospital Invoicing Data. Deutsches Arzteblatt international\| PubMed ID: 31774053	2019
Serum-derived factors of breast cancer patients with brain metastases alter permeability of a human blood-brain barrier model. Fluids and barriers of the CNS\| PubMed ID: 32321535	2020
Clinical Presentation, Treatment, and Outcome of Parathyroid Carcinoma: Results of the NEKAR Retrospective International Multicenter Study. Annals of surgery\| PubMed ID: 32649472	2022
Case Report: Abdominal Lymph Node Metastases of Parathyroid Carcinoma: Diagnostic Workup, Molecular Diagnosis, and Clinical Management. Frontiers in endocrinology\| PubMed ID: 33833736	2021
Prognostic impact of additive chemotherapy after curative resection of metachronous colorectal liver metastasis: a single-centre retrospective study. BMC cancer\| PubMed ID: 33941104	2021
Evaluation of diagnostic efficacy for localization of parathyroid adenoma in patients with primary hyperparathyroidism undergoing repeat surgery. Langenbeck's archives of surgery\| PubMed ID: 33993327	2021
G6b-B regulates an essential step in megakaryocyte maturation. Blood advances\| PubMed ID: 35134123	2022