Thomas Hankemeier

Division of Analytical Biosciences, Leiden University

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 10	2016
Publication title Cited by 25	2019

Other Publications

Article	Year
Microbial metabolomics: replacing trial-and-error by the unbiased selection and ranking of targets. Journal of industrial microbiology & biotechnology\| PubMed ID: 15895265	2005
Sign constraints improve the detection of differences between complex spectral data sets: LC-IR as an example. Analytical chemistry\| PubMed ID: 16351148	2005
Typical diffusion behaviour in packaging polymers - application to functional barriers. Food additives and contaminants\| PubMed ID: 16449064	2006
Microbial metabolomics with gas chromatography/mass spectrometry. Analytical chemistry\| PubMed ID: 16478122	2006
Effects of growth conditions and processing on Rehmannia glutinosa using fingerprint strategy. Planta medica\| PubMed ID: 16557461	2006
Hyphenation of infrared spectroscopy to liquid chromatography for qualitative and quantitative polymer analysis: degradation of poly(bisphenol A)carbonate. Journal of chromatography. A\| PubMed ID: 16735038	2006
Simultaneous quantitative analysis of metabolites using ion-pair liquid chromatography-electrospray ionization mass spectrometry. Analytical chemistry\| PubMed ID: 16970336	2006
Metabolite profiling of human urine by CE-ESI-MS using separation electrolytes at low pH. Electrophoresis\| PubMed ID: 17054083	2006
Metabolomics-based systems biology and personalized medicine: moving towards n = 1 clinical trials? Pharmacogenomics\| PubMed ID: 17054418	2006
CE-ESI-MS of biological anions in plastic capillaries at high pH. Electrophoresis\| PubMed ID: 17300131	2007
Microbial metabolomics: toward a platform with full metabolome coverage. Analytical biochemistry\| PubMed ID: 17765195	2007
Profiling of endogenous peptides in human synovial fluid by NanoLC-MS: method validation and peptide identification. Journal of proteome research\| PubMed ID: 17929855	2007
Recent methodology in the phytochemical analysis of ginseng. Phytochemical analysis : PCA\| PubMed ID: 18058794	2008
Higher mass loadability in comprehensive two-dimensional gas chromatography-mass spectrometry for improved analytical performance in metabolomics analysis. Journal of chromatography. A\| PubMed ID: 18155223	2008
Similarities and differences in lipidomics profiles among healthy monozygotic twin pairs. Omics : a journal of integrative biology\| PubMed ID: 18266560	2008
Comprehensive analysis of the metabolome of Pseudomonas putida S12 grown on different carbon sources. Molecular bioSystems\| PubMed ID: 18354785	2008
Lipidomic approach to evaluate rosuvastatin and atorvastatin at various dosages: investigating differential effects among statins. Current medical research and opinion\| PubMed ID: 18655752	2008
Solution titration by wall deprotonation during capillary filling of silicon oxide nanochannels. Analytical chemistry\| PubMed ID: 18826247	2008
RPLC-ion-trap-FTMS method for lipid profiling of plasma: method validation and application to p53 mutant mouse model. Journal of proteome research\| PubMed ID: 18841877	2008
Bioconversion of red ginseng saponins in the gastro-intestinal tract in vitro model studied by high-performance liquid chromatography-high resolution Fourier transform ion cyclotron resonanc... Journal of chromatography. A\| PubMed ID: 19041979	2009
Alkaloid profiling of the Chinese herbal medicine Fuzi by combination of matrix-assisted laser desorption ionization mass spectrometry with liquid chromatography-mass spectrometry. Journal of chromatography. A\| PubMed ID: 19095240	2009
Analytical strategies in lipidomics and applications in disease biomarker discovery. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences\| PubMed ID: 19233743	2009
Feasibility of electrodialysis as a fast and selective sample preparation method for the profiling of low-abundant peptides in biofluids. Electrophoresis\| PubMed ID: 19569123	2009
The effect of preanalytical factors on stability of the proteome and selected metabolites in cerebrospinal fluid (CSF). Journal of proteome research\| PubMed ID: 19845411	2009
Metabolic profiling of ultrasmall sample volumes with GC/MS: from microliter to nanoliter samples. Analytical chemistry\| PubMed ID: 19947586	2010
Mass-spectrometry-based metabolomics: limitations and recommendations for future progress with particular focus on nutrition research. Metabolomics : Official journal of the Metabolomic Society\| PubMed ID: 20046865	2009
Systems toxicology study of doxorubicin on rats using ultra performance liquid chromatography coupled with mass spectrometry based metabolomics. Metabolomics : Official journal of the Metabolomic Society\| PubMed ID: 20046867	2009
Equating, or correction for between-block effects with application to body fluid LC-MS and NMR metabolomics data sets. Analytical chemistry\| PubMed ID: 20052990	2010
Comprehensive LC-MS E lipidomic analysis using a shotgun approach and its application to biomarker detection and identification in osteoarthritis patients. Journal of proteome research\| PubMed ID: 20355720	2010
Comparative transcriptional profiling and preliminary study on heterosis mechanism of super-hybrid rice. Molecular plant\| PubMed ID: 20729474	2010
Quantitative proteomics and metabolomics analysis of normal human cerebrospinal fluid samples. Molecular & cellular proteomics : MCP\| PubMed ID: 20811074	2010
In vivo D2O labeling to quantify static and dynamic changes in cholesterol and cholesterol esters by high resolution LC/MS. Journal of lipid research\| PubMed ID: 20884843	2011
Systems biology-based diagnostic principles as pillars of the bridge between Chinese and Western medicine. Planta medica\| PubMed ID: 20979015	2010
Online capillary liquid-liquid electroextraction of peptides as fast pre-concentration prior to LC-MS. Electrophoresis\| PubMed ID: 21064141	2010
LC/MS analysis of stratum corneum lipids: ceramide profiling and discovery. Journal of lipid research\| PubMed ID: 21444759	2011
Semi-automated non-target processing in GC × GC-MS metabolomics analysis: applicability for biomedical studies. Metabolomics : Official journal of the Metabolomic Society\| PubMed ID: 21461033	2011
Traditional processing strongly affects metabolite composition by hydrolysis in Rehmannia glutinosa roots. Chemical & pharmaceutical bulletin\| PubMed ID: 21532190	2011
Plasma and liver lipidomics response to an intervention of rimonabant in ApoE*3Leiden.CETP transgenic mice. PloS one\| PubMed ID: 21611179	2011
Identifying static and kinetic lipid phenotypes by high resolution UPLC-MS: unraveling diet-induced changes in lipid homeostasis by coupling metabolomics and fluxomics. Journal of proteome research\| PubMed ID: 21744776	2011
Elemental composition determination based on MS(n). Bioinformatics (Oxford, England)\| PubMed ID: 21757467	2011
Attenuation of Slc27a5 gene expression followed by LC-MS measurement of bile acid reconjugation using metabolomics and a stable isotope tracer strategy. Journal of proteome research\| PubMed ID: 21819150	2011
ApoB siRNA-induced liver steatosis is resistant to clearance by the loss of fatty acid transport protein 5 (Fatp5). Lipids\| PubMed ID: 21826528	2011
Anacetrapib promotes reverse cholesterol transport and bulk cholesterol excretion in Syrian golden hamsters. Journal of lipid research\| PubMed ID: 21841206	2011
Single-electrolyte isotachophoresis using a nanochannel-induced depletion zone. Analytical chemistry\| PubMed ID: 21861489	2011
Linking biological activity with herbal constituents by systems biology-based approaches: effects of Panax ginseng in type 2 diabetic Goto-Kakizaki rats. Molecular bioSystems\| PubMed ID: 21901208	2011
Quantitative metabolomics based on gas chromatography mass spectrometry: status and perspectives. Metabolomics : Official journal of the Metabolomic Society\| PubMed ID: 21949491	2011
Sub-typing of rheumatic diseases based on a systems diagnosis questionnaire. PloS one\| PubMed ID: 21949766	2011
Localization of fatty acyl and double bond positions in phosphatidylcholines using a dual stage CID fragmentation coupled with ion mobility mass spectrometry. Journal of the American Society for Mass Spectrometry\| PubMed ID: 21953258	2011
The impact of delayed storage on the measured proteome and metabolome of human cerebrospinal fluid. Clinical chemistry\| PubMed ID: 21998343	2011
Enrichment of viable bacteria in a micro-volume by free-flow electrophoresis. Lab on a chip\| PubMed ID: 22008897	2012
[An ultra performance liquid chromatography-time-of-flight-mass spectrometric method for fast analysis of ginsenosides in Panax ginseng root]. Se pu = Chinese journal of chromatography / Zhongguo hua xue hui\| PubMed ID: 22032158	2011
An efficient hydrophilic interaction liquid chromatography separation of 7 phospholipid classes based on a diol column. Journal of chromatography. A\| PubMed ID: 22169191	2012
Understanding and classifying metabolite space and metabolite-likeness. PloS one\| PubMed ID: 22194963	2011
Lipidomics reveals multiple pathway effects of a multi-components preparation on lipid biochemistry in ApoE*3Leiden.CETP mice. PloS one\| PubMed ID: 22291936	2012
Metabolomics of cerebrospinal fluid reveals changes in the central nervous system metabolism in a rat model of multiple sclerosis. Metabolomics : Official journal of the Metabolomic Society\| PubMed ID: 22448154	2012
Metabolite identification using automated comparison of high-resolution multistage mass spectral trees. Analytical chemistry\| PubMed ID: 22612383	2012
Limits of miniaturization: assessing ITP performance in sub-micron and nanochannels. Lab on a chip\| PubMed ID: 22691967	2012
Hierarchical clustering analysis of blood plasma lipidomics profiles from mono- and dizygotic twin families. European journal of human genetics : EJHG\| PubMed ID: 22713803	2013
On-line large-volume electroextraction coupled to liquid chromatography-mass spectrometry to improve detection of peptides. Journal of chromatography. A\| PubMed ID: 22749583	2012
Quantitative profiling of oxylipins through comprehensive LC-MS/MS analysis: application in cardiac surgery. Analytical and bioanalytical chemistry\| PubMed ID: 22814969	2012
Instrument and process independent binning and baseline correction methods for liquid chromatography-high resolution-mass spectrometry deconvolution. Analytica chimica acta\| PubMed ID: 22840645	2012
MetiTree: a web application to organize and process high-resolution multi-stage mass spectrometry metabolomics data. Bioinformatics (Oxford, England)\| PubMed ID: 22851531	2012
Fragmentation trees for the structural characterisation of metabolites. Rapid communications in mass spectrometry : RCM\| PubMed ID: 22956319	2012
Characterization of rheumatoid arthritis subtypes using symptom profiles, clinical chemistry and metabolomics measurements. PloS one\| PubMed ID: 22984493	2012
OMG: Open Molecule Generator. Journal of cheminformatics\| PubMed ID: 22985496	2012
Feasibility of electroextraction as versatile sample preconcentration for fast and sensitive analysis of urine metabolites, demonstrated on acylcarnitines. Electrophoresis\| PubMed ID: 23001993	2012
Tunable ionic mobility filter for depletion zone isotachophoresis. Analytical chemistry\| PubMed ID: 23013213	2012
Increase in short-chain ceramides correlates with an altered lipid organization and decreased barrier function in atopic eczema patients. Journal of lipid research\| PubMed ID: 23024286	2012
Assessing the metabolic effects of prednisolone in healthy volunteers using urine metabolic profiling. Genome medicine\| PubMed ID: 23199229	2012
How do metabolites differ from their parent molecules and how are they excreted? Journal of chemical information and modeling\| PubMed ID: 23351040	2013
Automated pipeline for de novo metabolite identification using mass-spectrometry-based metabolomics. Analytical chemistry\| PubMed ID: 23368721	2013
Lipidomics of familial longevity. Aging cell\| PubMed ID: 23451766	2013
Pre-processing liquid chromatography/high-resolution mass spectrometry data: extracting pure mass spectra by deconvolution from the invariance of isotopic distribution. Rapid communications in mass spectrometry : RCM\| PubMed ID: 23592192	2013
Solvent Exchange Module for LC-NMR Hyphenation Using Machine Vision-Controlled Droplet Evaporation. Analytical chemistry\| PubMed ID: 23679001	2013
Three-phase electroextraction: a new (online) sample purification and enrichment method for bioanalysis. Analytical chemistry\| PubMed ID: 23724849	2013
A branched biosynthetic pathway is involved in production of roquefortine and related compounds in Penicillium chrysogenum. PloS one\| PubMed ID: 23776469	2013
Human metabolomics: strategies to understand biology. Current opinion in chemical biology\| PubMed ID: 23849548	2013
Microfluidic titer plate for stratified 3D cell culture. Lab on a chip\| PubMed ID: 23887749	2013
Proposed minimum reporting standards for chemical analysis Chemical Analysis Working Group (CAWG) Metabolomics Standards Initiative (MSI). Metabolomics : Official journal of the Metabolomic Society\| PubMed ID: 24039616	2007
Combined LC/MS-platform for analysis of all major stratum corneum lipids, and the profiling of skin substitutes. Biochimica et biophysica acta\| PubMed ID: 24120918	2014
Postprandial fatty acid specific changes in circulating oxylipins in lean and obese men after high-fat challenge tests. Molecular nutrition & food research\| PubMed ID: 24127338	2014
A new approach to untargeted integration of high resolution liquid chromatography-mass spectrometry data. Analytica chimica acta\| PubMed ID: 24139572	2013
Elastomeric microvalves as tunable nanochannels for concentration polarization. Lab on a chip\| PubMed ID: 24158567	2013
Novel key metabolites reveal further branching of the roquefortine/meleagrin biosynthetic pathway. The Journal of biological chemistry\| PubMed ID: 24225953	2013
The potential of electrophoretic sample pretreatment techniques and new instrumentation for bioanalysis, with a focus on peptidomics and metabolomics. Bioanalysis\| PubMed ID: 24256359	2013
Capillary electrophoresis-mass spectrometry using a flow-through microvial interface for cationic metabolome analysis. Electrophoresis\| PubMed ID: 24375112	2014
Novel hollow microneedle technology for depth-controlled microinjection-mediated dermal vaccination: a study with polio vaccine in rats. Pharmaceutical research\| PubMed ID: 24469907	2014
Isotachophoretic phenomena in electric field gradient focusing: perspectives for sample preparation and bioassays. Analytical chemistry\| PubMed ID: 24670194	2014
A protective lipidomic biosignature associated with a balanced omega-6/omega-3 ratio in fat-1 transgenic mice. PloS one\| PubMed ID: 24760204	2014
Phaseguide assisted liquid lamination for magnetic particle-based assays. Lab on a chip\| PubMed ID: 24832933	2014
Simple capillary electrophoresis-mass spectrometry method for complex glycan analysis using a flow-through microvial interface. Analytical chemistry\| PubMed ID: 24873509	2014
Metabolomics profiling for identification of novel potential markers in early prediction of preeclampsia. PloS one\| PubMed ID: 24873829	2014
A non-canonical NRPS is involved in the synthesis of fungisporin and related hydrophobic cyclic tetrapeptides in Penicillium chrysogenum. PloS one\| PubMed ID: 24887561	2014
Enhanced lipid isomer separation in human plasma using reversed-phase UPLC with ion-mobility/high-resolution MS detection. Journal of lipid research\| PubMed ID: 24891331	2014
Continuous-flow microelectroextraction for enrichment of low abundant compounds. Analytical chemistry\| PubMed ID: 24892382	2014
Phaseguides as tunable passive microvalves for liquid routing in complex microfluidic networks. Lab on a chip\| PubMed ID: 24989781	2014
Metabolic phenotyping reveals a lipid mediator response to ionizing radiation. Journal of proteome research\| PubMed ID: 25126707	2014
Analysis of oxysterols and vitamin D metabolites in mouse brain and cell line samples by ultra-high-performance liquid chromatography-atmospheric pressure photoionization-mass spectrometry. Journal of chromatography. A\| PubMed ID: 25204266	2014
Lab-on-a-Chip hyphenation with mass spectrometry: strategies for bioanalytical applications. Current opinion in biotechnology\| PubMed ID: 25232996	2015
Gas pressure assisted microliquid-liquid extraction coupled online to direct infusion mass spectrometry: a new automated screening platform for bioanalysis. Analytical chemistry\| PubMed ID: 25243401	2014
Roux-en-Y gastric bypass surgery, but not calorie restriction, reduces plasma branched-chain amino acids in obese women independent of weight loss or the presence of type 2 diabetes. Diabetes care\| PubMed ID: 25315204	2014
Testing tuberculosis drug efficacy in a zebrafish high-throughput translational medicine screen. Antimicrobial agents and chemotherapy\| PubMed ID: 25385118	2015
Systematic evaluation of commercially available ultra-high performance liquid chromatography columns for drug metabolite profiling: optimization of chromatographic peak capacity. Journal of chromatography. A\| PubMed ID: 25435462	2014
A mutasynthesis approach with a Penicillium chrysogenum ΔroqA strain yields new roquefortine D analogues. Chembiochem : a European journal of chemical biology\| PubMed ID: 25766600	2015
Individualization of treatments with drugs metabolized by CES1: combining genetics and metabolomics. Pharmacogenomics\| PubMed ID: 25896426	2015
Differentiation of neuroepithelial stem cells into functional dopaminergic neurons in 3D microfluidic cell culture. Lab on a chip\| PubMed ID: 25902196	2015
Matrix Effect Compensation in Small-Molecule Profiling for an LC-TOF Platform Using Multicomponent Postcolumn Infusion. Analytical chemistry\| PubMed ID: 25965142	2015
p53 attenuates AKT signaling by modulating membrane phospholipid composition. Oncotarget\| PubMed ID: 26061814	2015
Highly Selective, Reversible Inhibitor Identified by Comparative Chemoproteomics Modulates Diacylglycerol Lipase Activity in Neurons. Journal of the American Chemical Society\| PubMed ID: 26083464	2015
Microfluidic 3D cell culture: from tools to tissue models. Current opinion in biotechnology\| PubMed ID: 26094109	2015
First-Trimester Serum Acylcarnitine Levels to Predict Preeclampsia: A Metabolomics Approach. Disease markers\| PubMed ID: 26146448	2015
Effects of metformin on metabolite profiles and LDL cholesterol in patients with type 2 diabetes. Diabetes care\| PubMed ID: 26251408	2015
COordination of Standards in MetabOlomicS (COSMOS): facilitating integrated metabolomics data access. Metabolomics : Official journal of the Metabolomic Society\| PubMed ID: 26491418	2015
Serum amine-based metabolites and their association with outcomes in primary prevention implantable cardioverter-defibrillator patients. Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology\| PubMed ID: 26498162	2016
Oxylipid Profile of Low-Dose Aspirin Exposure: A Pharmacometabolomics Study. Journal of the American Heart Association\| PubMed ID: 26504148	2015
Quantitative profiling of oxylipins in plasma and atherosclerotic plaques of hypercholesterolemic rabbits. Analytical and bioanalytical chemistry\| PubMed ID: 26511226	2016
Sheathless capillary electrophoresis-mass spectrometry for anionic metabolic profiling. Electrophoresis\| PubMed ID: 26593113	2016
Collagen Induced Arthritis in DBA/1J Mice Associates with Oxylipin Changes in Plasma. Mediators of inflammation\| PubMed ID: 26604432	2015
Weight loss predictability by plasma metabolic signatures in adults with obesity and morbid obesity of the DiOGenes study. Obesity (Silver Spring, Md.)\| PubMed ID: 26813527	2016
Delayed luminescence: an experimental protocol for Chinese herbal medicines. Luminescence : the journal of biological and chemical luminescence\| PubMed ID: 26818567	2016
Metabolic effects of a 13-weeks lifestyle intervention in older adults: The Growing Old Together Study. Aging\| PubMed ID: 26824634	2016
Electroextraction and electromembrane extraction: Advances in hyphenation to analytical techniques. Electrophoresis\| PubMed ID: 26864699	2016
Migraine biomarkers in cerebrospinal fluid: A systematic review and meta-analysis. Cephalalgia : an international journal of headache\| PubMed ID: 26888294	2016
Discovery of biochemical biomarkers for aggression: A role for metabolomics in psychiatry. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics\| PubMed ID: 26913573	2016
A Chinese literature overview on ultra-weak photon emission as promising technology for studying system-based diagnostics. Complementary therapies in medicine\| PubMed ID: 27062943	2016
Bacterial surface layer proteins as a novel capillary coating material for capillary electrophoretic separations. Analytica chimica acta\| PubMed ID: 27155306	2016
Serum-Based Oxylipins Are Associated with Outcomes in Primary Prevention Implantable Cardioverter Defibrillator Patients. PloS one\| PubMed ID: 27281224	2016
Metabolic characterization of the natural progression of chronic hepatitis B. Genome medicine\| PubMed ID: 27286979	2016
Effects of growth altitude on chemical constituents and delayed luminescence properties in medicinal rhubarb. Journal of photochemistry and photobiology. B, Biology\| PubMed ID: 27327125	2016
Metabolomics profiling of the free and total oxidised lipids in urine by LC-MS/MS: application in patients with rheumatoid arthritis. Analytical and bioanalytical chemistry\| PubMed ID: 27405874	2016
Next-generation capillary electrophoresis-mass spectrometry approaches in metabolomics. Current opinion in biotechnology\| PubMed ID: 27455398	2016
Tracking biochemical changes correlated with ultra-weak photon emission using metabolomics. Journal of photochemistry and photobiology. B, Biology\| PubMed ID: 27597516	2016
Exploring the Inflammatory Metabolomic Profile to Predict Response to TNF-α Inhibitors in Rheumatoid Arthritis. PloS one\| PubMed ID: 27631111	2016
Pharmacokinetic Modeling of Paracetamol Uptake and Clearance in Zebrafish Larvae: Expanding the Allometric Scale in Vertebrates with Five Orders of Magnitude. Zebrafish\| PubMed ID: 27632065	2016
Metabolomics enables precision medicine: "A White Paper, Community Perspective". Metabolomics : Official journal of the Metabolomic Society\| PubMed ID: 27642271	2016
Differences between serum polar lipid profiles of male and female rheumatoid arthritis patients in response to glucocorticoid treatment. Inflammopharmacology\| PubMed ID: 27682325	2016
Classification for Longevity Potential: The Use of Novel Biomarkers. Frontiers in public health\| PubMed ID: 27840811	2016
Measuring ultra-weak photon emission as a non-invasive diagnostic tool for detecting early-stage type 2 diabetes: A step toward personalized medicine. Journal of photochemistry and photobiology. B, Biology\| PubMed ID: 27888740	2017
Quantitative profiling of endocannabinoids and related -acylethanolamines in human CSF using nano LC-MS/MS. Journal of lipid research\| PubMed ID: 27999147	2017
Integration of pharmacometabolomics with pharmacokinetics and pharmacodynamics: towards personalized drug therapy. Metabolomics : Official journal of the Metabolomic Society\| PubMed ID: 28058041	2017
Feasibility of ultra-performance liquid chromatography-ion mobility-time-of-flight mass spectrometry in analyzing oxysterols. Journal of chromatography. A\| PubMed ID: 28118975	2017
Characterization of the therapeutic properties of Chinese herbal materials by measuring delayed luminescence and dendritic cell-based immunomodulatory response. Journal of photochemistry and photobiology. B, Biology\| PubMed ID: 28147303	2017
Spontaneous ultra-weak photon emission in correlation to inflammatory metabolism and oxidative stress in a mouse model of collagen-induced arthritis. Journal of photochemistry and photobiology. B, Biology\| PubMed ID: 28199905	2017
Role of amino acids in rheumatoid arthritis studied by metabolomics. International journal of rheumatic diseases\| PubMed ID: 28328075	2019
Metabolic network failures in Alzheimer's disease: A biochemical road map. Alzheimer's & dementia : the journal of the Alzheimer's Association\| PubMed ID: 28341160	2017
Ultra-weak photon emission as a dynamic tool for monitoring oxidative stress metabolism. Scientific reports\| PubMed ID: 28450732	2017
Integrating clinical metabolomics-based biomarker discovery and clinical pharmacology to enable precision medicine. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences\| PubMed ID: 28502671	2017
Towards personalized treatment of pain using a quantitative systems pharmacology approach. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences\| PubMed ID: 28506867	2017
Activity-based protein profiling reveals off-target proteins of the FAAH inhibitor BIA 10-2474. Science (New York, N.Y.)\| PubMed ID: 28596366	2017
Fetal Metabolic Stress Disrupts Immune Homeostasis and Induces Proinflammatory Responses in Human Immunodeficiency Virus Type 1- and Combination Antiretroviral Therapy-Exposed Infants. The Journal of infectious diseases\| PubMed ID: 28633455	2017
Endocannabinoid tone is higher in healthy lean South Asian than white Caucasian men. Scientific reports\| PubMed ID: 28790443	2017
Metabolomics based markers predict type 2 diabetes in a 14-year follow-up study. Metabolomics : Official journal of the Metabolomic Society\| PubMed ID: 28804275	2017
Membrane-free culture and real-time barrier integrity assessment of perfused intestinal epithelium tubes. Nature communications\| PubMed ID: 28811479	2017
A Mendelian Randomization Study of Metabolite Profiles, Fasting Glucose, and Type 2 Diabetes. Diabetes\| PubMed ID: 28847883	2017
Cellular glutathione levels in HL-60 cells during respiratory burst are not correlated with ultra-weak photon emission. Journal of photochemistry and photobiology. B, Biology\| PubMed ID: 28926741	2017
Blood-based metabolic signatures in Alzheimer's disease. Alzheimer's & dementia (Amsterdam, Netherlands)\| PubMed ID: 28951883	2017
The future of metabolomics in ELIXIR. F1000Research\| PubMed ID: 29043062	2017
Therapy response testing of breast cancer in a 3D high-throughput perfused microfluidic platform. BMC cancer\| PubMed ID: 29096610	2017
Circulating metabolites and general cognitive ability and dementia: Evidence from 11 cohort studies. Alzheimer's & dementia : the journal of the Alzheimer's Association\| PubMed ID: 29316447	2018
Caloric restriction lowers endocannabinoid tonus and improves cardiac function in type 2 diabetes. Nutrition & diabetes\| PubMed ID: 29343706	2018
Pharmacological targeting of ROS reaction network in myeloid leukemia cells monitored by ultra-weak photon emission. Oncotarget\| PubMed ID: 29416750	2018
A metabolomics study of Qiliqiangxin in a rat model of heart failure: a reverse pharmacology approach. Scientific reports\| PubMed ID: 29487344	2018
Development and application of a UHPLC-MS/MS metabolomics based comprehensive systemic and tissue-specific screening method for inflammatory, oxidative and nitrosative stress. Analytical and bioanalytical chemistry\| PubMed ID: 29497765	2018
Strategies to assess and optimize stability of endogenous amines during cerebrospinal fluid sampling. Metabolomics : Official journal of the Metabolomic Society\| PubMed ID: 29527143	2018
Mass spectrometric recommendations for Quan/Qual analysis using liquid-chromatography coupled to quadrupole time-of-flight mass spectrometry. Analytica chimica acta\| PubMed ID: 29655429	2018
Fusing metabolomics data sets with heterogeneous measurement errors. PloS one\| PubMed ID: 29698490	2018
High-Resolution Analysis of the Peptidoglycan Composition in Streptomyces coelicolor. Journal of bacteriology\| PubMed ID: 30061355	2018
Gene Expression of Endocannabinoid System Components in Skeletal Muscle and Adipose Tissue of South Asians and White Caucasians with Overweight. Obesity (Silver Spring, Md.)\| PubMed ID: 30070030	2018
Baseline metabolic profiles of early rheumatoid arthritis patients achieving sustained drug-free remission after initiating treat-to-target tocilizumab, methotrexate, or the combination: ins... Arthritis research & therapy\| PubMed ID: 30322408	2018
Altered bile acid profile associates with cognitive impairment in Alzheimer's disease-An emerging role for gut microbiome. Alzheimer's & dementia : the journal of the Alzheimer's Association\| PubMed ID: 30337151	2019
Altered bile acid profile in mild cognitive impairment and Alzheimer's disease: Relationship to neuroimaging and CSF biomarkers. Alzheimer's & dementia : the journal of the Alzheimer's Association\| PubMed ID: 30337152	2019
Persistent metabolic changes in HIV-infected patients during the first year of combination antiretroviral therapy. Scientific reports\| PubMed ID: 30446683	2018
PhenoMeNal: processing and analysis of metabolomics data in the cloud. GigaScience\| PubMed ID: 30535405	2019
Utility of sheathless capillary electrophoresis-mass spectrometry for metabolic profiling of limited sample amounts. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences\| PubMed ID: 30554093	2019
Covariates in Pharmacometric Repeated Time-to-Event Models: Old and New (Pre)Selection Tools. The AAPS journal\| PubMed ID: 30565031	2018
Activity-Based Protein Profiling Identifies α-Ketoamides as Inhibitors for Phospholipase A2 Group XVI. ACS chemical biology\| PubMed ID: 30620559	2019
Blood-Based Biomarkers of Quinpirole Pharmacology: Cluster-Based PK/PD and Metabolomics to Unravel the Underlying Dynamics in Rat Plasma and Brain. CPT: pharmacometrics & systems pharmacology\| PubMed ID: 30680960	2019
High Fat Diet Increases Circulating Endocannabinoids Accompanied by Increased Synthesis Enzymes in Adipose Tissue. Frontiers in physiology\| PubMed ID: 30687125	2018
Discovery of novel glycerolated quinazolinones from Streptomyces sp. MBT27. Journal of industrial microbiology & biotechnology\| PubMed ID: 30729343	2019
Automated microfluidic cell culture of stem cell derived dopaminergic neurons. Scientific reports\| PubMed ID: 30741972	2019
Impact of post-hatching maturation on the pharmacokinetics of paracetamol in zebrafish larvae. Scientific reports\| PubMed ID: 30770889	2019
Global testing of shifts in metabolic phenotype. Metabolomics : Official journal of the Metabolomic Society\| PubMed ID: 30830386	2018
The influence of neuronal electrical activity on the mammalian central clock metabolome. Metabolomics : Official journal of the Metabolomic Society\| PubMed ID: 30830420	2018
Capillary Electrophoresis-Mass Spectrometry for Metabolic Profiling of Biomass-Limited Samples. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 30847790	2019
Interoperable and scalable data analysis with microservices: applications in metabolomics. Bioinformatics (Oxford, England)\| PubMed ID: 30851093	2019
Assessing the suitability of capillary electrophoresis-mass spectrometry for biomarker discovery in plasma-based metabolomics. Electrophoresis\| PubMed ID: 31025710	2019
CE-MS for anionic metabolic profiling: An overview of methodological developments. Electrophoresis\| PubMed ID: 31106868	2019
Mechanistic and Quantitative Understanding of Pharmacokinetics in Zebrafish Larvae through Nanoscale Blood Sampling and Metabolite Modeling of Paracetamol. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 31371482	2019
LC-MS/MS analysis of the central energy and carbon metabolites in biological samples following derivatization by dimethylaminophenacyl bromide. Journal of chromatography. A\| PubMed ID: 31395359	2019
Intersubject and Intrasubject Variability of Potential Plasma and Urine Metabolite and Protein Biomarkers in Healthy Human Volunteers. Clinical pharmacology and therapeutics\| PubMed ID: 31400148	2019
Fast LC-ESI-MS/MS analysis and influence of sampling conditions for gut metabolites in plasma and serum. Scientific reports\| PubMed ID: 31451722	2019
Interstitial Flow Recapitulates Gemcitabine Chemoresistance in A 3D Microfluidic Pancreatic Ductal Adenocarcinoma Model by Induction of Multidrug Resistance Proteins. International journal of molecular sciences\| PubMed ID: 31546820	2019
Supervised Multidimensional Item Response Theory Modeling of Pediatric Iatrogenic Withdrawal Symptoms. CPT: pharmacometrics & systems pharmacology\| PubMed ID: 31612647	2019
Chemical Diversity and Classification of Secondary Metabolites in Nine Bryophyte Species. Metabolites\| PubMed ID: 31614655	2019
Impaired serine metabolism complements LRRK2-G2019S pathogenicity in PD patients. Parkinsonism & related disorders\| PubMed ID: 31621607	2019
STATegra, a comprehensive multi-omics dataset of B-cell differentiation in mouse. Scientific data\| PubMed ID: 31672995	2019