Chi-Hao Luan

High Throughput Analysis Laboratory, Northwestern University

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 6	2016

Other Publications

Article	Year
Identification of the N-terminal functional domains of Cdk5 by molecular truncation and computer modeling. Proteins\| PubMed ID: 12112670	2002
Crystal structure of the cytoskeleton-associated protein glycine-rich (CAP-Gly) domain. The Journal of biological chemistry\| PubMed ID: 12221106	2002
Tethered dimers as NAD synthetase inhibitors with antibacterial activity. Journal of medicinal chemistry\| PubMed ID: 12852767	2003
Structural genomics for Caenorhabditis elegans: high throughput protein expression analysis. Protein expression and purification\| PubMed ID: 14766299	2004
High-throughput expression of C. elegans proteins. Genome research\| PubMed ID: 15489332	2004
Identification and characterization of nonsubstrate based inhibitors of the essential dengue and West Nile virus proteases. Bioorganic & medicinal chemistry\| PubMed ID: 15582469	2005
Protein production and crystallization at SECSG -- an overview. Journal of structural and functional genomics\| PubMed ID: 16211524	2005
Tethered dimer inhibitors of NAD synthetase: parallel synthesis of an aryl-substituted SAR library. Journal of combinatorial chemistry\| PubMed ID: 16283799	2005
Improving solubility of Shewanella oneidensis MR-1 and Clostridium thermocellum JW-20 proteins expressed into Esherichia coli. Journal of proteome research\| PubMed ID: 16335938	2005
Antibacterial nicotinamide adenine dinucleotide synthetase inhibitors: amide- and ether-linked tethered dimers with alpha-amino acid end groups. Journal of medicinal chemistry\| PubMed ID: 17489580	2007
Domain selection combined with improved cloning strategy for high throughput expression of higher eukaryotic proteins. BMC biotechnology\| PubMed ID: 17663785	2007
A high throughput platform for eukaryotic genes. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 18542866	2008
Antagonism of 4-substituted 1,4-dihydropyridine-3,5-dicarboxylates toward voltage-dependent L-type Ca2+ channels Ca V 1.3 and Ca V 1.2. Bioorganic & medicinal chemistry\| PubMed ID: 20382537	2010
Targeting MgrA-mediated virulence regulation in Staphylococcus aureus. Chemistry & biology\| PubMed ID: 21867918	2011
High-throughput screen for identifying small molecules that target fungal zinc homeostasis. PloS one\| PubMed ID: 21980385	2011
CaV1.3-selective L-type calcium channel antagonists as potential new therapeutics for Parkinson's disease. Nature communications\| PubMed ID: 23093183	2012
Phosphoglycerate mutase 1 coordinates glycolysis and biosynthesis to promote tumor growth. Cancer cell\| PubMed ID: 23153533	2012
Structure of severe fever with thrombocytopenia syndrome virus nucleocapsid protein in complex with suramin reveals therapeutic potential. Journal of virology\| PubMed ID: 23576501	2013
Structure-activity relationship of N,N'-disubstituted pyrimidinetriones as Ca(V)1.3 calcium channel-selective antagonists for Parkinson's disease. Journal of medicinal chemistry\| PubMed ID: 23651412	2013
Antagonism of L-type Ca2+ channels CaV1.3 and CaV1.2 by 1,4-dihydropyrimidines and 4H-pyrans as dihydropyridine mimics. Bioorganic & medicinal chemistry\| PubMed ID: 23688558	2013
A fluorescence-based thermal shift assay identifies inhibitors of mitogen activated protein kinase kinase 4. PloS one\| PubMed ID: 24339940	2013
Structural characterization of a hypothetical protein: a potential agent involved in trimethylamine metabolism in Catenulispora acidiphila. Journal of structural and functional genomics\| PubMed ID: 24562475	2014
Ligand screening using fluorescence thermal shift analysis (FTS). Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 24590724	2014
Nanoscale Synaptic Membrane Mimetic Allows Unbiased High Throughput Screen That Targets Binding Sites for Alzheimer's-Associated Aβ Oligomers. PloS one\| PubMed ID: 25928376	2015
Identification of Small-Molecule Inhibitors of Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels. Journal of biomolecular screening\| PubMed ID: 26045196	2015
HMG-CoA Reductase Inhibitors Bind to PPARα to Upregulate Neurotrophin Expression in the Brain and Improve Memory in Mice. Cell metabolism\| PubMed ID: 26118928	2015
Novel High Content Screen Detects Compounds That Promote Neurite Regeneration from Cochlear Spiral Ganglion Neurons. Scientific reports\| PubMed ID: 26521685	2015
A Genome-wide RNAi Screen for Microtubule Bundle Formation and Lysosome Motility Regulation in Drosophila S2 Cells. Cell reports\| PubMed ID: 26774481	2016
Loop-to-helix transition in the structure of multidrug regulator AcrR at the entrance of the drug-binding cavity. Journal of structural biology\| PubMed ID: 26796657	2016
Structure and mechanism of the essential two-component signal-transduction system WalKR in Staphylococcus aureus. Nature communications\| PubMed ID: 26987594	2016
Fluorescence-based thermal shift data on multidrug regulator AcrR from Salmonella enterica subsp. entrica serovar Typhimurium str. LT2. Data in brief\| PubMed ID: 27054155	2016
Crystal structures of the transpeptidase domain of the Mycobacterium tuberculosis penicillin-binding protein PonA1 reveal potential mechanisms of antibiotic resistance. The FEBS journal\| PubMed ID: 27101811	2016
Identification and characterization of PPARα ligands in the hippocampus. Nature chemical biology\| PubMed ID: 27748752	2016