Kevin Mills

Centre for Translational Omics, University College London

Affiliated withUniversity College London

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 3	2016

Other Publications

Article	Year
Synthesis of novel internal standards for the quantitative determination of plasma ceramide trihexoside in Fabry disease by tandem mass spectrometry. FEBS letters\| PubMed ID: 11943216	2002
Unrepaired DNA breaks in p53-deficient cells lead to oncogenic gene amplification subsequent to translocations. Cell\| PubMed ID: 12110179	2002
Fourth ventricular CART reduces food and water intake and produces a conditioned taste aversion in rats. Behavioral neuroscience\| PubMed ID: 12369811	2002
The underglycosylation of plasma alpha 1-antitrypsin in congenital disorders of glycosylation type I is not random. Glycobiology\| PubMed ID: 12626422	2003
The role of DNA breaks in genomic instability and tumorigenesis. Immunological reviews\| PubMed ID: 12846809	2003
Rad54 and DNA Ligase IV cooperate to maintain mammalian chromatid stability. Genes & development\| PubMed ID: 15175260	2004
Collaboration of homologous recombination and nonhomologous end-joining factors for the survival and integrity of mice and cells. Genes & development\| PubMed ID: 15175261	2004
Monitoring the clinical and biochemical response to enzyme replacement therapy in three children with Fabry disease. European journal of pediatrics\| PubMed ID: 15243806	2004
The synthesis of internal standards for the quantitative determination of sphingolipids by tandem mass spectrometry. Rapid communications in mass spectrometry : RCM\| PubMed ID: 15909321	2005
Non-invasive screening method for Fabry disease by measuring globotriaosylceramide in whole urine samples using tandem mass spectrometry. Molecular genetics and metabolism\| PubMed ID: 15979031	2005
Determination of coenzyme Q10 status in blood mononuclear cells, skeletal muscle, and plasma by HPLC with di-propoxy-coenzyme Q10 as an internal standard. Clinical chemistry\| PubMed ID: 16306103	2005
Genomic instability and aging-like phenotype in the absence of mammalian SIRT6. Cell\| PubMed ID: 16439206	2006
53BP1 and p53 synergize to suppress genomic instability and lymphomagenesis. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16492765	2006
Diagnosis of congenital disorders of glycosylation type-I using protein chip technology. Proteomics\| PubMed ID: 16552784	2006
XRCC4 suppresses medulloblastomas with recurrent translocations in p53-deficient mice. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16670198	2006
Quantitative analysis of s-adenosylmethionine and s-adenosylhomocysteine in neurulation-stage mouse embryos by liquid chromatography tandem mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences\| PubMed ID: 16890031	2006
Integrity of the methylation cycle is essential for mammalian neural tube closure. Birth defects research. Part A, Clinical and molecular teratology\| PubMed ID: 16933307	2006
Dynamic clustered distribution of hemagglutinin resolved at 40 nm in living cell membranes discriminates between raft theories. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17959773	2007
Chromosome neighborhood composition determines translocation outcomes after exposure to high-dose radiation in primary cells. Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology\| PubMed ID: 18060570	2007
Homologous recombination is necessary for normal lymphocyte development. Molecular and cellular biology\| PubMed ID: 18212067	2008
Treatment of Fabry disease with different dosing regimens of agalsidase: effects on antibody formation and GL-3. Molecular genetics and metabolism\| PubMed ID: 18424138	2008
Abnormal sympathetic innervation of viable myocardium and the substrate of ventricular tachycardia after myocardial infarction. Journal of the American College of Cardiology\| PubMed ID: 18534275	2008
SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging. Cell\| PubMed ID: 19041753	2008
Discovery of a new biomarker for the mucopolysaccharidoses (MPS), dipeptidyl peptidase IV (DPP-IV; CD26), by SELDI-TOF mass spectrometry. Molecular genetics and metabolism\| PubMed ID: 19153055	2009
Gb(3)/creatinine biomarkers for Fabry disease: issues to consider. Molecular genetics and metabolism\| PubMed ID: 19428279	2009
Complex oncogenic translocations with gene amplification are initiated by specific DNA breaks in lymphocytes. Cancer research\| PubMed ID: 19435904	2009
Colocalization of somatic and meiotic double strand breaks near the Myc oncogene on mouse chromosome 15. Genes, chromosomes & cancer\| PubMed ID: 19603522	2009
Aging in inbred strains of mice: study design and interim report on median lifespans and circulating IGF1 levels. Aging cell\| PubMed ID: 19627267	2009
Engraftment, differentiation, and functional benefits of autologous cardiosphere-derived cells in porcine ischemic cardiomyopathy. Circulation\| PubMed ID: 19738142	2009
Global changes in processing of mRNA 3' untranslated regions characterize clinically distinct cancer subtypes. Cancer research\| PubMed ID: 19934316	2009
A novel method for the direct measurement of urinary conjugated metabolites of alpha-tocopherol and its use in diabetes. Molecular nutrition & food research\| PubMed ID: 20169581	2010
New role for LEKTI in skin barrier formation: label-free quantitative proteomic identification of caspase 14 as a novel target for the protease inhibitor LEKTI. Journal of proteome research\| PubMed ID: 20533828	2010
Genotypic and phenotypic spectrum of pyridoxine-dependent epilepsy (ALDH7A1 deficiency). Brain : a journal of neurology\| PubMed ID: 20554659	2010
Widespread genomic breaks generated by activation-induced cytidine deaminase are prevented by homologous recombination. Nature immunology\| PubMed ID: 20657597	2010
Nuclear positioning, higher-order folding, and gene expression of Mmu15 sequences are refractory to chromosomal translocation. Chromosoma\| PubMed ID: 20703494	2011
ARTEMIS stabilizes the genome and modulates proliferative responses in multipotent mesenchymal cells. BMC biology\| PubMed ID: 20979627	2010
Epidermal changes associated with symptomatic resolution of dandruff: biomarkers of scalp health. International journal of dermatology\| PubMed ID: 21182510	2011
Scalp stratum corneum histamine levels: novel sampling method reveals association with itch resolution in dandruff/seborrhoeic dermatitis treatment. Acta dermato-venereologica\| PubMed ID: 21336476	2011
Brain lipid-binding protein: a marker of differentiation in neuroblastic tumors. Journal of pediatric surgery\| PubMed ID: 21683222	2011
Rhabdomyosarcomas in aging A/J mice. PloS one\| PubMed ID: 21853140	2011
Quantitative analysis of myo-inositol in urine, blood and nutritional supplements by high-performance liquid chromatography tandem mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences\| PubMed ID: 21856255	2011
2D DIGE analysis of maternal plasma for potential biomarkers of Down Syndrome. Proteome science\| PubMed ID: 21929753	2011
Identification of new biomarkers for Down's syndrome in maternal plasma. Journal of proteomics\| PubMed ID: 22456345	2012
The development of a peptide SRM-based tandem mass spectrometry assay for prenatal screening of Down syndrome. Journal of proteomics\| PubMed ID: 22543281	2012
Measurement of plasma B6 vitamer profiles in children with inborn errors of vitamin B6 metabolism using an LC-MS/MS method. Journal of inherited metabolic disease\| PubMed ID: 22576361	2013
The identification of a new role for LEKTI in the skin: The use of protein 'bait' arrays to detect defective trafficking of dermcidin in the skin of patients with Netherton syndrome. Journal of proteomics\| PubMed ID: 22588119	2012
Activation-induced cytidine deaminase-initiated off-target DNA breaks are detected and resolved during S phase. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 22826323	2012
Reference measurement procedures for Alzheimer's disease cerebrospinal fluid biomarkers: definitions and approaches with focus on amyloid β42. Biomarkers in medicine\| PubMed ID: 22917143	2012
Urinary conjugated α-tocopheronolactone--a biomarker of oxidative stress in children with type 1 diabetes. Free radical biology & medicine\| PubMed ID: 23108104	2013
The identification of new biomarkers for identifying and monitoring kidney disease and their translation into a rapid mass spectrometry-based test: evidence of presymptomatic kidney disease ... Journal of proteome research\| PubMed ID: 23464927	2013
Progression in multiple sclerosis is associated with low endogenous NCAM. Journal of neurochemistry\| PubMed ID: 23495921	2013
Attenuating homologous recombination stimulates an AID-induced antileukemic effect. The Journal of experimental medicine\| PubMed ID: 23589568	2013
Coenzyme Q10 quantification in muscle, fibroblasts and cerebrospinal fluid by liquid chromatography/tandem mass spectrometry using a novel deuterated internal standard. Rapid communications in mass spectrometry : RCM\| PubMed ID: 23592193	2013
A new method for the rapid diagnosis of protein N-linked congenital disorders of glycosylation. Journal of proteome research\| PubMed ID: 23742123	2013
Thymosin β4-sulfoxide attenuates inflammatory cell infiltration and promotes cardiac wound healing. Nature communications\| PubMed ID: 23820300	2013
A DNA break- and phosphorylation-dependent positive feedback loop promotes immunoglobulin class-switch recombination. Nature immunology\| PubMed ID: 24097111	2013
Tumor suppression: putting p53 in context. Cell cycle (Georgetown, Tex.)\| PubMed ID: 24131920	2013
Physiological expression of the PI3K-activating mutation Pik3ca(H1047R) combines with Apc loss to promote development of invasive intestinal adenocarcinomas in mice. The Biochemical journal\| PubMed ID: 24320611	2014
Epilepsy due to PNPO mutations: genotype, environment and treatment affect presentation and outcome. Brain : a journal of neurology\| PubMed ID: 24645144	2014
Growth associated protein (GAP-43): cloning and the development of a sensitive ELISA for neurological disorders. Journal of neuroimmunology\| PubMed ID: 25175067	2014
Changes in regulation of human monocyte proteins in response to IgG from patients with antiphospholipid syndrome. Blood\| PubMed ID: 25301710	2014
Pathogenic autoantibodies from patients with lupus nephritis cause reduced tyrosine phosphorylation of podocyte proteins, including tubulin. Lupus science & medicine\| PubMed ID: 25396061	2014
Current applications of biomarkers in cardiomyopathies. Expert review of cardiovascular therapy\| PubMed ID: 26106935	2015
Residential Segregation and Overweight/Obesity Among African-American Adults: A Critical Review. Frontiers in public health\| PubMed ID: 26191522	2015
Proteomic Discovery and Development of a Multiplexed Targeted MRM-LC-MS/MS Assay for Urine Biomarkers of Extracellular Matrix Disruption in Mucopolysaccharidoses I, II, and VI. Analytical chemistry\| PubMed ID: 26537538	2015
Identification of novel CSF biomarkers for neurodegeneration and their validation by a high-throughput multiplexed targeted proteomic assay. Molecular neurodegeneration\| PubMed ID: 26627638	2015
Increased cerebrospinal fluid soluble TREM2 concentration in Alzheimer's disease. Molecular neurodegeneration\| PubMed ID: 26754172	2016
Inositol for the prevention of neural tube defects: a pilot randomised controlled trial. The British journal of nutrition\| PubMed ID: 26847388	2016
Erratum to: Identification of novel CSF biomarkers for neurodegeneration and their validation by a high-throughput multiplexed targeted proteomic assay. Molecular neurodegeneration\| PubMed ID: 26907468	2016
Inositol for prevention of neural tube defects: a pilot randomised controlled trial - CORRIGENDUM. The British journal of nutrition\| PubMed ID: 26917444	2016
Formate supplementation enhances folate-dependent nucleotide biosynthesis and prevents spina bifida in a mouse model of folic acid-resistant neural tube defects. Biochimie\| PubMed ID: 26924399	2016
Comparison of Two Dimension-Reduction Methods for Network Simulation Models. Journal of research of the National Institute of Standards and Technology\| PubMed ID: 26989599	2011
Chromosomal Instability Affects the Tumorigenicity of Glioblastoma Tumor-Initiating Cells. Cancer discovery\| PubMed ID: 27001151	2016
Quantitative Proteomic Analysis of Stratum Corneum Dysfunction in Adult Chronic Atopic Dermatitis. The Journal of investigative dermatology\| PubMed ID: 27091361	2016
Global serum glycoform profiling for the investigation of dystroglycanopathies & Congenital Disorders of Glycosylation. Molecular genetics and metabolism reports\| PubMed ID: 27134828	2016
Identification of novel bile acids as biomarkers for the early diagnosis of Niemann-Pick C disease. FEBS letters\| PubMed ID: 27139891	2016
A rapid high throughput proteomic method based on profiling of proteolytic free peptides to assess post-delivery degradation of placental tissue. Placenta\| PubMed ID: 27161200	2016
Simulating Timescale Dynamics of Network Traffic Using Homogeneous Modeling. Journal of research of the National Institute of Standards and Technology\| PubMed ID: 27274931	2006
The embryological basis of subclinical hypertrophic cardiomyopathy. Scientific reports\| PubMed ID: 27323879	2016
Regulation of post-Golgi LH3 trafficking is essential for collagen homeostasis. Nature communications\| PubMed ID: 27435297	2016
An optimised method for the proteomic profiling of full thickness human skin. Biological procedures online\| PubMed ID: 27445641	2016
Exploring Collective Dynamics in Communication Networks. Journal of research of the National Institute of Standards and Technology\| PubMed ID: 27446726	2002