Raymond Chang

Laboratory of Neurodegenerative Diseases, The University of Hong Kong - HKU

Affiliated withThe University of Hong Kong - HKU

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 26	2007

Other Publications

Article	Year
p38 MAP kinase is involved in lipopolysaccharide-induced dopaminergic neuronal cell death in rat mesencephalic neuron-glia cultures. Annals of the New York Academy of Sciences\| PubMed ID: 12076985	2002
Involvement of double-stranded RNA-dependent protein kinase and phosphorylation of eukaryotic initiation factor-2alpha in neuronal degeneration. Journal of neurochemistry\| PubMed ID: 12437593	2002
Asian therapies for cancer--coming of age. Journal of alternative and complementary medicine (New York, N.Y.)\| PubMed ID: 12470433	2002
Brain cancer: a case of glioblastoma multiforme. Journal of alternative and complementary medicine (New York, N.Y.)\| PubMed ID: 12470435	2002
Bioactive polysaccharides from traditional Chinese medicine herbs as anticancer adjuvants. Journal of alternative and complementary medicine (New York, N.Y.)\| PubMed ID: 12470436	2002
Role of acupuncture in the treatment of female infertility. Fertility and sterility\| PubMed ID: 12477502	2002
Phosphorylation of eukaryotic initiation factor-2alpha (eIF2alpha) is associated with neuronal degeneration in Alzheimer's disease. Neuroreport\| PubMed ID: 12499843	2002
BAD and Bcl-2 regulation are early events linking neuronal endoplasmic reticulum stress to mitochondria-mediated apoptosis. Brain research. Molecular brain research\| PubMed ID: 12531534	2002
Trial spacing is a determinant of cue interaction. Journal of experimental psychology. Animal behavior processes\| PubMed ID: 12561131	2003
Images in clinical medicine. "Corkscrew" esophagus. The New England journal of medicine\| PubMed ID: 12711742	2003
Benzodiazepines as potent and selective bradykinin B1 antagonists. Journal of medicinal chemistry\| PubMed ID: 12723943	2003
Discovery of a potent, non-peptide bradykinin B1 receptor antagonist. Journal of the American Chemical Society\| PubMed ID: 12812482	2003
Backward conditioning: mediation by the context. Journal of experimental psychology. Animal behavior processes\| PubMed ID: 12884677	2003
A family of highly selective allosteric modulators of the metabotropic glutamate receptor subtype 5. Molecular pharmacology\| PubMed ID: 12920211	2003
Upstream signaling pathways leading to the activation of double-stranded RNA-dependent serine/threonine protein kinase in beta-amyloid peptide neurotoxicity. The Journal of biological chemistry\| PubMed ID: 12975376	2003
Difference in mGluR5 interaction between positive allosteric modulators from two structural classes. Annals of the New York Academy of Sciences\| PubMed ID: 14684495	2003
Comparing excitatory backward and forward conditioning. The Quarterly journal of experimental psychology. B, Comparative and physiological psychology\| PubMed ID: 14690847	2004
Reduction of calcium release from the endoplasmic reticulum could only provide partial neuroprotection against beta-amyloid peptide toxicity. Journal of neurochemistry\| PubMed ID: 14713297	2003
Massive preexposure and preexposure in multiple contexts attenuate the context specificity of latent inhibition. Learning & behavior\| PubMed ID: 14733485	2003
Generation and characterization of a human bradykinin receptor B1 transgenic rat as a pharmacodynamic model. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 15051800	2004
Modulation of calcium/calmodulin kinase-II provides partial neuroprotection against beta-amyloid peptide toxicity. The European journal of neuroscience\| PubMed ID: 15090032	2004
Reconstruction of complex oncologic chest wall defects: a 10-year experience. Annals of plastic surgery\| PubMed ID: 15096930	2004
Pharmacological characterization and radioligand binding properties of a high-affinity, nonpeptide, bradykinin B1 receptor antagonist. European journal of pharmacology\| PubMed ID: 15363953	2004
In vivo evaluation of [11C]N-(2-chloro-5-thiomethylphenyl)-N'-(3-methoxy-phenyl)-N'-methylguanidine ([11C]GMOM) as a potential PET radiotracer for the PCP/NMDA receptor. Nuclear medicine and biology\| PubMed ID: 15464396	2004
Characterization of polysaccharides from the flowers of Nerium indicum and their neuroprotective effects. International journal of molecular medicine\| PubMed ID: 15492866	2004
Isolated cortical venous thrombosis presenting as subarachnoid hemorrhage: a report of three cases. AJNR. American journal of neuroradiology\| PubMed ID: 15569729	2004
2,3-diaminopyridine bradykinin B1 receptor antagonists. Journal of medicinal chemistry\| PubMed ID: 15588075	2004
Immune modulatory effects of Prunella vulgaris L. International journal of molecular medicine\| PubMed ID: 15702244	2005
2,3-Diaminopyridine as a platform for designing structurally unique nonpeptide bradykinin B1 receptor antagonists. Bioorganic & medicinal chemistry letters\| PubMed ID: 15837330	2005
Stable expression of EBERs in immortalized nasopharyngeal epithelial cells confers resistance to apoptotic stress. Molecular carcinogenesis\| PubMed ID: 16086371	2005
Neuroprotective effects of anti-aging oriental medicine Lycium barbarum against beta-amyloid peptide neurotoxicity. Experimental gerontology\| PubMed ID: 16139464	2005
Immune modulatory effects of Prunella vulgaris L. on monocytes/macrophages. International journal of molecular medicine\| PubMed ID: 16273294	2005
Inhibition of acute nociceptive responses in rat spinal cord by a bradykinin B1 receptor antagonist. European journal of pharmacology\| PubMed ID: 16310181	2005
Novel neuroprotective effects of the aqueous extracts from Verbena officinalis Linn. Neuropharmacology\| PubMed ID: 16406021	2006
Cyclopropylamino acid amide as a pharmacophoric replacement for 2,3-diaminopyridine. Application to the design of novel bradykinin B1 receptor antagonists. Journal of medicinal chemistry\| PubMed ID: 16480259	2006
Beta-amyloid peptides induces neuronal apoptosis via a mechanism independent of unfolded protein responses. Apoptosis : an international journal on programmed cell death\| PubMed ID: 16532272	2006
In vivo evaluation in rats of [(18)F]1-(2-fluoroethyl)-4-[(4-cyanophenoxy)methyl]piperidine as a potential radiotracer for PET assessment of CNS sigma-1 receptors. Nuclear medicine and biology\| PubMed ID: 16546675	2006
Cytoprotective effects of Lycium barbarum against reducing stress on endoplasmic reticulum. International journal of molecular medicine\| PubMed ID: 16685430	2006
Design, synthesis, and in vivo efficacy of glycine transporter-1 (GlyT1) inhibitors derived from a series of [4-phenyl-1-(propylsulfonyl)piperidin-4-yl]methyl benzamides. ChemMedChem\| PubMed ID: 16902933	2006
Preclinical acute toxicity studies and dosimetry estimates of the novel sigma-1 receptor radiotracer, [18F]SFE. Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging\| PubMed ID: 16924428	2006
Neuroprotective effects of Lycium barbarum Lynn on protecting retinal ganglion cells in an ocular hypertension model of glaucoma. Experimental neurology\| PubMed ID: 17045262	2007
Potent bradykinin B1 receptor antagonists: 4-substituted phenyl cyclohexanes. Bioorganic & medicinal chemistry letters\| PubMed ID: 17428657	2007
In vitro and in vivo binding of neuroactive steroids to the sigma-1 receptor as measured with the positron emission tomography radioligand [18F]FPS. Synapse (New York, N.Y.)\| PubMed ID: 17447254	2007
New polysaccharide from Nerium indicum protects neurons via stress kinase signaling pathway. Brain research\| PubMed ID: 17475226	2007
Significance of molecular signaling for protein translation control in neurodegenerative diseases. Neuro-Signals\| PubMed ID: 17496426	2006
Characterizing the neuroprotective effects of alkaline extract of Lycium barbarum on beta-amyloid peptide neurotoxicity. Brain research\| PubMed ID: 17568570	2007
Characterization of the effects of anti-aging medicine Fructus lycii on beta-amyloid peptide neurotoxicity. International journal of molecular medicine\| PubMed ID: 17611646	2007
Use of anti-aging herbal medicine, Lycium barbarum, against aging-associated diseases. What do we know so far? Cellular and molecular neurobiology\| PubMed ID: 17710531	2008
Alpha-hydroxy amides as a novel class of bradykinin B1 selective antagonists. Bioorganic & medicinal chemistry letters\| PubMed ID: 18061443	2008
Antagonizing beta-amyloid peptide neurotoxicity of the anti-aging fungus Ganoderma lucidum. Brain research\| PubMed ID: 18083148	2008
2-Aminobenzophenones as a novel class of bradykinin B1 receptor antagonists. Journal of medicinal chemistry\| PubMed ID: 18553956	2008
Dietary oxyresveratrol prevents parkinsonian mimetic 6-hydroxydopamine neurotoxicity. Free radical biology & medicine\| PubMed ID: 18675900	2008
Dexras1 interacts with FE65 to regulate FE65-amyloid precursor protein-dependent transcription. The Journal of biological chemistry\| PubMed ID: 18922798	2008
Effects of all-trans-retinoic acid on human SH-SY5Y neuroblastoma as in vitro model in neurotoxicity research. Neurotoxicology\| PubMed ID: 19056420	2009
Low molecular weight Abeta induces collapse of endoplasmic reticulum. Molecular and cellular neurosciences\| PubMed ID: 19386229	2009
Protective effects of pinostilbene, a resveratrol methylated derivative, against 6-hydroxydopamine-induced neurotoxicity in SH-SY5Y cells. The Journal of nutritional biochemistry\| PubMed ID: 19443200	2010
Polysaccharides from wolfberry antagonizes glutamate excitotoxicity in rat cortical neurons. Cellular and molecular neurobiology\| PubMed ID: 19499323	2009
Calcium dysregulation in Alzheimer's disease: from mechanisms to therapeutic opportunities. Progress in neurobiology\| PubMed ID: 19664678	2009
Modulation of microglia by Wolfberry on the survival of retinal ganglion cells in a rat ocular hypertension model. Journal of ocular biology, diseases, and informatics\| PubMed ID: 19672466	2009
Could PKR inhibition modulate human neurodegeneration? Expert review of neurotherapeutics\| PubMed ID: 19831834	2009
Anti-aging herbal medicine--how and why can they be used in aging-associated neurodegenerative diseases? Ageing research reviews\| PubMed ID: 19833234	2010
Modulation of neuroimmune responses on glia in the central nervous system: implication in therapeutic intervention against neuroinflammation. Cellular & molecular immunology\| PubMed ID: 19887044	2009
Temporal relationship of autophagy and apoptosis in neurons challenged by low molecular weight Î²-amyloid peptide. Journal of cellular and molecular medicine\| PubMed ID: 20015199	2011
A pro-drug of the green tea polyphenol (-)-epigallocatechin-3-gallate (EGCG) prevents differentiated SH-SY5Y cells from toxicity induced by 6-hydroxydopamine. Neuroscience letters\| PubMed ID: 20026175	2010
Erratum: Modulation of microglia by Wolfberry on the survival of retinal ganglion cells in a rat ocular hypertension model. Journal of ocular biology, diseases, and informatics\| PubMed ID: 20046845	2009
Modulation of morphological changes of microglia and neuroprotection by monocyte chemoattractant protein-1 in experimental glaucoma. Cellular & molecular immunology\| PubMed ID: 20081877	2010
Transcriptional regulation of human FE65, a ligand of Alzheimer's disease amyloid precursor protein, by Sp1. Journal of cellular biochemistry\| PubMed ID: 20091743	2010
Neuroprotective effects of polysaccharides from wolfberry, the fruits of Lycium barbarum, against homocysteine-induced toxicity in rat cortical neurons. Journal of Alzheimer's disease : JAD\| PubMed ID: 20157238	2010
Up-regulation of crystallins is involved in the neuroprotective effect of wolfberry on survival of retinal ganglion cells in rat ocular hypertension model. Journal of cellular biochemistry\| PubMed ID: 20336662	2010
The putative neurodegenerative links between depression and Alzheimer's disease. Progress in neurobiology\| PubMed ID: 20441786	2010
Beneficial effects of cinnamon proanthocyanidins on the formation of specific advanced glycation endproducts and methylglyoxal-induced impairment on glucose consumption. Journal of agricultural and food chemistry\| PubMed ID: 20476737	2010
Modulation of mitochondrial calcium as a pharmacological target for Alzheimer's disease. Ageing research reviews\| PubMed ID: 20553970	2010
Genetic sphingosine kinase 1 deficiency significantly decreases synovial inflammation and joint erosions in murine TNF-alpha-induced arthritis. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 20644167	2010
Sulfur-containing constituents and one 1H-pyrrole-2-carboxylic acid derivative from pineapple [Ananas comosus (L.) Merr.] fruit. Phytochemistry\| PubMed ID: 20843530	2010
Light deprivation induces depression-like behavior and suppresses neurogenesis in diurnal mongolian gerbil (Meriones unguiculatus). Cell transplantation\| PubMed ID: 21054936	2011
Lycium barbarum polysaccharides reduce neuronal damage, blood-retinal barrier disruption and oxidative stress in retinal ischemia/reperfusion injury. PloS one\| PubMed ID: 21298100	2011
Drug discovery from Chinese medicine against neurodegeneration in Alzheimer's and vascular dementia. Chinese medicine\| PubMed ID: 21513513	2011
Neurodegeneration of the retina in mouse models of Alzheimer's disease: what can we learn from the retina? Age (Dordrecht, Netherlands)\| PubMed ID: 21559868	2011
Endoplasmic Reticulum Stress Induces Tau Pathology and Forms a Vicious Cycle: Implication in Alzheimer's Disease Pathogenesis. Journal of Alzheimer's disease : JAD\| PubMed ID: 22101233	2011
Lycium barbarum polysaccharides protect mice liver from carbon tetrachloride-induced oxidative stress and necroinflammation. Journal of ethnopharmacology\| PubMed ID: 22138659	2012
From small to big molecules: how do we prevent and delay the progression of age-related neurodegeneration? Current pharmaceutical design\| PubMed ID: 22211681	2012