Jean-Pierre Raufman

Department of Medicine, University of Maryland School of Medicine

Affiliated withUniversity of Maryland School of Medicine VA Maryland Health Care System

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 8	2016

Other Publications

Article	Year
Seroprevalence of H. pylori infection and symptoms of upper gastrointestinal tract disease in two groups of health-care workers. Digestive diseases and sciences\| PubMed ID: 11855543	2002
Heterozygosity for factor V Leiden and G20210A prothrombin genotypes in a patient with mesenteric vein thrombosis. Digestive diseases and sciences\| PubMed ID: 11911349	2002
Deoxycholic acid conjugates are muscarinic cholinergic receptor antagonists. Pharmacology\| PubMed ID: 12119452	2002
Lithocholylcholine, a bile acid/acetylcholine hybrid, is a muscarinic receptor antagonist. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 12235229	2002
Functional interaction of lithocholic acid conjugates with M3 muscarinic receptors on a human colon cancer cell line. Biochimica et biophysica acta\| PubMed ID: 12379313	2002
Selective interaction of bile acids with muscarinic receptors: a case of molecular mimicry. European journal of pharmacology\| PubMed ID: 12464352	2002
Activation of muscarinic receptor signaling by bile acids: physiological and medical implications. Digestive diseases and sciences\| PubMed ID: 12924634	2003
Transactivation of the epidermal growth factor receptor mediates cholinergic agonist-induced proliferation of H508 human colon cancer cells. Cancer research\| PubMed ID: 14583469	2003
Vasodilatory effects of cholinergic agonists are greatly diminished in aorta from M3R-/- mice. European journal of pharmacology\| PubMed ID: 15189773	2004
Hepatitis C knowledge among primary care residents: is our teaching adequate for the times? The American journal of gastroenterology\| PubMed ID: 15330909	2004
3',5'-Cyclic diguanylic acid (c-di-GMP) inhibits basal and growth factor-stimulated human colon cancer cell proliferation. Biochemical and biophysical research communications\| PubMed ID: 15721270	2005
Cholinergic agonist-induced pepsinogen secretion from murine gastric chief cells is mediated by M1 and M3 muscarinic receptors. American journal of physiology. Gastrointestinal and liver physiology\| PubMed ID: 15933222	2005
A survey of credentialing practices of gastrointestinal endoscopy centers in the United States. Journal of clinical gastroenterology\| PubMed ID: 15942436	2005
Deoxycholyltaurine-induced vasodilation of rodent aorta is nitric oxide- and muscarinic M(3) receptor-dependent. European journal of pharmacology\| PubMed ID: 15964566	2005
Declining gastrointestinal opportunistic infections in HIV-infected persons: a triumph of science and a challenge for our HAARTs and minds. The American journal of gastroenterology\| PubMed ID: 15984965	2005
Bile acid-induced proliferation of a human colon cancer cell line is mediated by transactivation of epidermal growth factor receptors. Biochemical pharmacology\| PubMed ID: 16139803	2005
Quality assessment of colonoscopic cecal intubation: an analysis of 6 years of continuous practice at a university hospital. The American journal of gastroenterology\| PubMed ID: 16494586	2006
Matrix metalloproteinase-7-catalyzed release of HB-EGF mediates deoxycholyltaurine-induced proliferation of a human colon cancer cell line. Biochemical pharmacology\| PubMed ID: 17222808	2007
Human cecal bile acids: concentration and spectrum. American journal of physiology. Gastrointestinal and liver physiology\| PubMed ID: 17412828	2007
Deoxycholyltaurine rescues human colon cancer cells from apoptosis by activating EGFR-dependent PI3K/Akt signaling. Journal of cellular physiology\| PubMed ID: 18064605	2008
Genetic ablation of M3 muscarinic receptors attenuates murine colon epithelial cell proliferation and neoplasia. Cancer research\| PubMed ID: 18483237	2008
Acetylcholine release by human colon cancer cells mediates autocrine stimulation of cell proliferation. American journal of physiology. Gastrointestinal and liver physiology\| PubMed ID: 18653726	2008
Muscarinic receptors and ligands in cancer. American journal of physiology. Cell physiology\| PubMed ID: 19036940	2009
Akt-dependent NF-kappaB activation is required for bile acids to rescue colon cancer cells from stress-induced apoptosis. Experimental cell research\| PubMed ID: 19056378	2009
Acetylcholine-induced activation of M3 muscarinic receptors stimulates robust matrix metalloproteinase gene expression in human colon cancer cells. American journal of physiology. Gastrointestinal and liver physiology\| PubMed ID: 19221016	2009
Computational models for drug inhibition of the human apical sodium-dependent bile acid transporter. Molecular pharmaceutics\| PubMed ID: 19673539	2009
Gastrointestinal peptides and regulation of gastric acid secretion. Current opinion in endocrinology, diabetes, and obesity\| PubMed ID: 19855274	2010
Scopolamine treatment and muscarinic receptor subtype-3 gene ablation augment azoxymethane-induced murine liver injury. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 20197374	2010
In vivo magnetic resonance imaging to detect biliary excretion of 19F-labeled drug in mice. Drug metabolism and disposition: the biological fate of chemicals\| PubMed ID: 21270105	2011
Muscarinic receptor agonists stimulate human colon cancer cell migration and invasion. American journal of physiology. Gastrointestinal and liver physiology\| PubMed ID: 21273532	2011
Muscarinic receptor subtype-3 gene ablation and scopolamine butylbromide treatment attenuate small intestinal neoplasia in Apcmin/+ mice. Carcinogenesis\| PubMed ID: 21705482	2011
Bile acids regulate cardiovascular function. Clinical and translational science\| PubMed ID: 21707953	2011
Anatomic classification of the endoscopic appearance of the normal appendiceal orifice: a novel tool for recognition and documentation of cecal intubation. Clinical anatomy (New York, N.Y.)\| PubMed ID: 21913231	2012
Muscarinic receptor agonists stimulate matrix metalloproteinase 1-dependent invasion of human colon cancer cells. Biochemical and biophysical research communications\| PubMed ID: 22027145	2011
Effects of deoxycholylglycine, a conjugated secondary bile acid, on myogenic tone and agonist-induced contraction in rat resistance arteries. PloS one\| PubMed ID: 22359652	2012
Src-mediated aryl hydrocarbon and epidermal growth factor receptor cross talk stimulates colon cancer cell proliferation. American journal of physiology. Gastrointestinal and liver physiology\| PubMed ID: 22361730	2012
SlimQuick™ - associated hepatotoxicity in a woman with alpha-1 antitrypsin heterozygosity. World journal of hepatology\| PubMed ID: 22567188	2012
Src-mediated cross-talk between farnesoid X and epidermal growth factor receptors inhibits human intestinal cell proliferation and tumorigenesis. PloS one\| PubMed ID: 23119029	2012
Design and characterization of a novel fluorinated magnetic resonance imaging agent for functional analysis of bile Acid transporter activity. Pharmaceutical research\| PubMed ID: 23319170	2013
RNase-L deficiency exacerbates experimental colitis and colitis-associated cancer. Inflammatory bowel diseases\| PubMed ID: 23567782	2013
Cholinergic muscarinic receptor activation augments murine intestinal epithelial cell proliferation and tumorigenesis. BMC cancer\| PubMed ID: 23617763	2013
Effects of modulating M3 muscarinic receptor activity on azoxymethane-induced liver injury in mice. Biochemical pharmacology\| PubMed ID: 23707755	2013
Bedside to bench: role of muscarinic receptor activation in ultrarapid growth of colorectal cancer in a patient with pheochromocytoma. Mayo Clinic proceedings\| PubMed ID: 24100192	2013
The Cdc42/Rac nucleotide exchange factor protein β1Pix (Pak-interacting exchange factor) modulates β-catenin transcriptional activity in colon cancer cells: evidence for direct interaction o... The Journal of biological chemistry\| PubMed ID: 24129564	2013
Muscarinic receptor signaling in colon cancer. Cancers\| PubMed ID: 24212649	2011
Phrygian Cap Appearance of a Mouse Gallbladder on Magnetic Resonance Imaging. Journal of veterinary science & medical diagnosis\| PubMed ID: 24371838	2013
The role of matrix metalloproteinases in colorectal cancer. Cancers\| PubMed ID: 24518611	2014
Divergent effects of muscarinic receptor subtype gene ablation on murine colon tumorigenesis reveals association of M3R and zinc finger protein 277 expression in colon neoplasia. Molecular cancer\| PubMed ID: 24694019	2014
In vivo performance of a novel fluorinated magnetic resonance imaging agent for functional analysis of bile acid transport. Molecular pharmaceutics\| PubMed ID: 24708306	2014
Design and evaluation of a novel trifluorinated imaging agent for assessment of bile acid transport using fluorine magnetic resonance imaging. Journal of pharmaceutical sciences\| PubMed ID: 25196788	2014
M1 muscarinic receptors modify oxidative stress response to acetaminophen-induced acute liver injury. Free radical biology & medicine\| PubMed ID: 25452146	2015
Type 3 Muscarinic Receptors Contribute to Clearance of Citrobacter rodentium. Inflammatory bowel diseases\| PubMed ID: 25985244	2015
Pharmacokinetics and Tolerability of Intravenous Sildenafil in Two Subjects with Child-Turcotte-Pugh Class C Cirrhosis and Renal Dysfunction. Digestive diseases and sciences\| PubMed ID: 26143343	2015
Slc10a2-null mice uncover colon cancer-promoting actions of endogenous fecal bile acids. Carcinogenesis\| PubMed ID: 26210740	2015
Role of the Aryl Hydrocarbon Receptor in Colon Neoplasia. Cancers\| PubMed ID: 26264025	2015
M1 Muscarinic Receptor Deficiency Attenuates Azoxymethane-Induced Chronic Liver Injury in Mice. Scientific reports\| PubMed ID: 26374068	2015
Butyrate inhibits pro-proliferative miR-92a by diminishing c-Myc-induced miR-17-92a cluster transcription in human colon cancer cells. Molecular cancer\| PubMed ID: 26463716	2015
Type 3 muscarinic receptors contribute to intestinal mucosal homeostasis and clearance of Nippostrongylus brasiliensis through induction of TH2 cytokines. American journal of physiology. Gastrointestinal and liver physiology\| PubMed ID: 27173511	2016