ultrasound-guided-botulinum-toxin-injections-method-treating

Ultrasound-guided Botulinum Toxin-A Injections: A Method of Treating Sialorrhea

Neurological diseases can be complicated by sialorrhea, an excessive flow of saliva. Patients suffering from moderate to severe sialorrhea have an ...

University of Torino, San Luigi Gonzaga Hospital

To review our method of perform needle biopsies of renal masses.

Diagnostic accuracy and clinical impact of imaging-guided needle biopsy of renal masses. Retrospective analysis on 150 cases.

Primary tracheo-bronchial amyloidosis studied with 64-slice MDCT (2D and 3D reconstructions).

Our aim was to analyse the results of our first 100 radiofrequency ablation (RFA) procedures, of primary (nonsmall-cell lung cancers, NSCLC) and secondary (MTS) lung cancers to assess what lessons could be learned from our experience.

Radiofrequency ablation of thoracic tumours: lessons learned with ablation of 100 lesions.

The study was done to analyse the results of a series of radiofrequency ablation (RFA) procedures performed on hepatic metastases (METS) from breast cancer in order to evaluate the clinical impact of this therapy.

Radiofrequency thermal ablation (RFA) of hepatic metastases (METS) from breast cancer (BC): an adjunctive tool in the multimodal treatment of advanced disease.

To evaluate the long-term effects of radiofrequency ablation (RFA) of renal masses (RM) and compare them with surgery.

T1a as the sole selection criterion for RFA of renal masses: randomized controlled trials versus surgery should not be postponed.

Lung ultrasound (LUS) may accurately diagnose pneumothorax. However, there is uncertainty about its usefulness in the quantification of pneumothorax size. To determine the ability of LUS in the semi-quantification of pneumothorax volume, we compared the projection of the lung point (LP) with the pneumothorax volume measured by computerized tomography (CT) and the interpleural distance on chest radiography (CXR).

Semi-quantification of pneumothorax volume by lung ultrasound.

We present the case of a 29-years-old male patient, affected by a voluminous post-traumatic mesenteric cyst, a rare abdominal disease; our patient represents a rarely affected age group. Treatment was based on interventional radiology with an US-guided drainage and sclerosis by ethyl alcohol of the lesion. The intervention performed on this patient represents the application of a standardized radiological technique to a new contest, mesenteric cysts, whose gold-standard treatment is represented in literature by surgery. In our case we obtained an optimal result, with complete regression of the treated cyst: it proved to be an effective, feasible, safe and minimally invasive procedure.

Percutaneous drainage and sclerosis of mesenteric cysts: literature overview and report of an innovative approach.

Corrigendum to "Percutaneous drainage and sclerosis of mesenteric cysts: Literature overview and report of an innovative approach" [Int. J. Surg. 12 (2014) S90-S93].

To identify risk factors for the adverse events and determine the diagnostic yield of a large series of image-guided thoracic biopsies performed in a single institution.

Safety and diagnostic performance of image-guided lung biopsy in the targeted therapy era.

Literature provides reports only of a limited follow-up single injection of botulinum toxin-A (BoNT-A) in patients with sialorrhea. The aim of our study is to evaluate the long-lasting efficacy and safety of ultrasound-guided BoNT-A injections for severe sialorrhea secondary to neurological dysphagia. We enrolled 38 severe adult sialorrhea patients referred consecutively to the neurology unit and performed bilateral parotid and submandibular gland BoNT-A injections under ultrasound guidance. The outcomes of the study were reduction of sialorrhea, duration of therapeutic effect, and subjective patient- and caregiver-reported satisfaction. A total of 113 BoNT-A administrations were given during the study period with a mean duration of follow-up of 20.2 ± 4.4 months. We observed a significant decrease from baseline in mean number of daily aspirations and a significant improvement in patient- and caregiver-reported outcomes following ultrasound-guided BoNT-A injections (p < 0.001 vs baseline for all comparisons) and the mean duration of the efficacy was 5.6 ± 1 months. No major treatment-related adverse events occurred and a low incidence of minor adverse events was reported. This study confirms the long-lasting efficacy and safety of ultrasound-guided BoNT-A injections for sialorrhea, regardless of the causative neurological disorder. These results should encourage the use of BoNT-A in the treatment of severe sialorrhea and highlight the role of ultrasound guidance to obtain optimal results in terms of safety and reproducible outcomes.

Long-term follow-up of ultrasound-guided botulinum toxin-A injections for sialorrhea in neurological dysphagia.

While acute arterial occlusion causes life-threatening ischemia and organ damage requiring urgent revascularization, the incidental identification of arterial occlusions in asymptomatic patients represents a therapeutic dilemma in clinicians. Does chronic asymptomatic artery occlusion require specific treatment?

Article	Year
Diagnostic accuracy and clinical impact of imaging-guided needle biopsy of renal masses. Retrospective analysis on 150 cases. European radiology\| PubMed ID: 20809129	2011
Primary tracheo-bronchial amyloidosis studied with 64-slice MDCT (2D and 3D reconstructions). Thorax\| PubMed ID: 21163808	2011
Radiofrequency ablation of thoracic tumours: lessons learned with ablation of 100 lesions. La Radiologia medica\| PubMed ID: 24234185	2014
Radiofrequency thermal ablation (RFA) of hepatic metastases (METS) from breast cancer (BC): an adjunctive tool in the multimodal treatment of advanced disease. La Radiologia medica\| PubMed ID: 24297589	2014
T1a as the sole selection criterion for RFA of renal masses: randomized controlled trials versus surgery should not be postponed. Cardiovascular and interventional radiology\| PubMed ID: 24337348	2014
Semi-quantification of pneumothorax volume by lung ultrasound. Intensive care medicine\| PubMed ID: 25056671	2014
Percutaneous drainage and sclerosis of mesenteric cysts: literature overview and report of an innovative approach. International journal of surgery (London, England)\| PubMed ID: 25183644	2014
Corrigendum to "Percutaneous drainage and sclerosis of mesenteric cysts: Literature overview and report of an innovative approach" [Int. J. Surg. 12 (2014) S90-S93]. International journal of surgery (London, England)\| PubMed ID: 25662476	2015
Safety and diagnostic performance of image-guided lung biopsy in the targeted therapy era. La Radiologia medica\| PubMed ID: 25930161	2015
Long-term follow-up of ultrasound-guided botulinum toxin-A injections for sialorrhea in neurological dysphagia. Journal of neurology\| PubMed ID: 26410746	2015
When collateral vessels matter: asymptomatic Leriche syndrome. Clinical case reports\| PubMed ID: 26576282	2015
Gastropancreatic fistula in a patient with chronic pancreatitis and IPMN. BMJ case reports\| PubMed ID: 27222278	2016

Marco Busso

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