Jens Kurreck

Department of Applied Biochemistry, Institute of Biotechnology, Berlin University of Technology

Affiliated withInstitute of Biotechnology, Berlin University of Technology

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 7	2016

Other Publications

Article	Year
Sequence requirements in the catalytic core of the "10-23" DNA enzyme. The Journal of biological chemistry\| PubMed ID: 12192010	2002
Comparative study of DNA enzymes and ribozymes against the same full-length messenger RNA of the vanilloid receptor subtype I. The Journal of biological chemistry\| PubMed ID: 11751899	2002
Design of antisense oligonucleotides stabilized by locked nucleic acids. Nucleic acids research\| PubMed ID: 11972327	2002
Antisense technologies. Improvement through novel chemical modifications. European journal of biochemistry\| PubMed ID: 12694176	2003
Comparison of different antisense strategies in mammalian cells using locked nucleic acids, 2'-O-methyl RNA, phosphorothioates and small interfering RNA. Nucleic acids research\| PubMed ID: 12799446	2003
RNA cleaving '10-23' DNAzymes with enhanced stability and activity. Nucleic acids research\| PubMed ID: 14530446	2003
Nucleic acids chemistry and biology. Angewandte Chemie (International ed. in English)\| PubMed ID: 14618569	2003
Cellular uptake and localization of a Cy3-labeled siRNA specific for the serine/threonine kinase Pim-1. Oligonucleotides\| PubMed ID: 15000825	2003
Expediting target identification and validation through RNAi. Expert opinion on biological therapy\| PubMed ID: 15006736	2004
Gaining target access for deoxyribozymes. Journal of molecular biology\| PubMed ID: 15136038	2004
Differentiating the functional role of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha (EPAS-1) by the use of RNA interference: erythropoietin is a HIF-2alpha target gene in Hep3B and K... FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 15240563	2004
Application of locked nucleic acids to improve aptamer in vivo stability and targeting function. Nucleic acids research\| PubMed ID: 15509871	2004
Antisense and RNA interference approaches to target validation in pain research. Current opinion in drug discovery & development\| PubMed ID: 15603251	2004
Deletion analysis in the catalytic region of the 10-23 DNA enzyme. FEBS letters\| PubMed ID: 15642375	2005
Maintaining inhibition: siRNA double expression vectors against coxsackieviral RNAs. Journal of molecular biology\| PubMed ID: 15670596	2005
Local RNA target structure influences siRNA efficacy: systematic analysis of intentionally designed binding regions. Journal of molecular biology\| PubMed ID: 15843020	2005
Developing an effective RNA interference strategy against a plus-strand RNA virus: silencing of coxsackievirus B3 and its cognate coxsackievirus-adenovirus receptor. Biological chemistry\| PubMed ID: 16164410	2005
Comparative crystallization and preliminary X-ray diffraction studies of locked nucleic acid and RNA stems of a tenascin C-binding aptamer. Acta crystallographica. Section F, Structural biology and crystallization communications\| PubMed ID: 16820689	2006
Silencing of vanilloid receptor TRPV1 by RNAi reduces neuropathic and visceral pain in vivo. Biochemical and biophysical research communications\| PubMed ID: 16996476	2006
RNA interference in pain research. Journal of neurochemistry\| PubMed ID: 17029593	2006
Antinociceptive effect of antisense oligonucleotides against the vanilloid receptor VR1/TRPV1. Neurochemistry international\| PubMed ID: 17045702	2007
siRNA efficiency: structure or sequence-that is the question. Journal of biomedicine & biotechnology\| PubMed ID: 17057371	2006
Strand-specific silencing of a picornavirus by RNA interference: evidence for the superiority of plus-strand specific siRNAs. Antiviral research\| PubMed ID: 17112603	2007
Investigation of TRPV1 loss-of-function phenotypes in transgenic shRNA expressing and knockout mice. Molecular and cellular neurosciences\| PubMed ID: 18249134	2008
Inhibition of translation in living eukaryotic cells by an RNA G-quadruplex motif. RNA (New York, N.Y.)\| PubMed ID: 18515550	2008
Cardiac-targeted RNA interference mediated by an AAV9 vector improves cardiac function in coxsackievirus B3 cardiomyopathy. Journal of molecular medicine (Berlin, Germany)\| PubMed ID: 18548221	2008
Design of LNA-modified siRNAs against the highly structured 5' UTR of coxsackievirus B3. FEBS letters\| PubMed ID: 18691577	2008
Inhibition of picornaviruses by means of RNA interference. Nucleic acids symposium series (2004)\| PubMed ID: 18776254	2008
ESF-EMBO symposium: antiviral applications of RNA interference. Retrovirology\| PubMed ID: 18801178	2008
RNA interference: from basic research to therapeutic applications. Angewandte Chemie (International ed. in English)\| PubMed ID: 19153977	2009
Antiviral activity of highly potent siRNAs against echovirus 30 and its receptor. Journal of virological methods\| PubMed ID: 19187792	2009
Long-term cardiac-targeted RNA interference for the treatment of heart failure restores cardiac function and reduces pathological hypertrophy. Circulation\| PubMed ID: 19237664	2009
Locked nucleic acid aptamers. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 19377996	2009
Combination of soluble coxsackievirus-adenovirus receptor and anti-coxsackievirus siRNAs exerts synergistic antiviral activity against coxsackievirus B3. Antiviral research\| PubMed ID: 19591879	2009
RNA interference: Perspectives and caveats. Journal of RNAi and gene silencing : an international journal of RNA and gene targeting research\| PubMed ID: 19771205	2005
Application of small interfering RNAs modified by unlocked nucleic acid (UNA) to inhibit the heart-pathogenic coxsackievirus B3. FEBS letters\| PubMed ID: 20005874	2010
Proof of RNA interference in humans after systemic delivery of siRNAs. Angewandte Chemie (International ed. in English)\| PubMed ID: 20648509	2010
Rapid construction of adeno-associated virus vectors expressing multiple short hairpin RNAs with high antiviral activity against echovirus 30. Oligonucleotides\| PubMed ID: 20649454	2010
Inhibition of adenovirus infections by siRNA-mediated silencing of early and late adenoviral gene functions. Antiviral research\| PubMed ID: 20708037	2010
Design of small interfering RNAs for antiviral applications. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 21431692	2011
Pharmacological and biological antiviral therapeutics for cardiac coxsackievirus infections. Molecules (Basel, Switzerland)\| PubMed ID: 21989310	2011
Application of Mutated miR-206 Target Sites Enables Skeletal Muscle-specific Silencing of Transgene Expression of Cardiotropic AAV9 Vectors. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 23439498	2013
Adenovirus vector-mediated RNA interference for the inhibition of human parvovirus B19 replication. Virus research\| PubMed ID: 23770153	2013
A novel method for the quantification of adeno-associated virus vectors for RNA interference applications using quantitative polymerase chain reaction and purified genomic adeno-associated v... Human gene therapy methods\| PubMed ID: 23987130	2013
A novel artificial microRNA expressing AAV vector for phospholamban silencing in cardiomyocytes improves Ca2+ uptake into the sarcoplasmic reticulum. PloS one\| PubMed ID: 24670775	2014
Identification and characterization of RNA guanine-quadruplex binding proteins. Nucleic acids research\| PubMed ID: 24771345	2014
Combination of RNA interference and virus receptor trap exerts additive antiviral activity in coxsackievirus B3-induced myocarditis in mice. The Journal of infectious diseases\| PubMed ID: 25193982	2015
Enhanced suppression of adenovirus replication by triple combination of anti-adenoviral siRNAs, soluble adenovirus receptor trap sCAR-Fc and cidofovir. Antiviral research\| PubMed ID: 26026665	2015
Targeting Highly Structured RNA by Cooperative Action of siRNAs and Helper Antisense Oligomers in Living Cells. PloS one\| PubMed ID: 26308932	2015
Use of a three-dimensional humanized liver model for the study of viral gene vectors. Journal of biotechnology\| PubMed ID: 26356676	2015
Application of modified antisense oligonucleotides and siRNAs as antiviral drugs. Future medicinal chemistry\| PubMed ID: 26381598	2015
Hepatitis E Virus Superinfection and Clinical Progression in Hepatitis B Patients. EBioMedicine\| PubMed ID: 26844288	2015
The Coxsackievirus and Adenovirus Receptor: Glycosylation and the Extracellular D2 Domain Are Not Required for Coxsackievirus B3 Infection. Journal of virology\| PubMed ID: 27030267	2016
Biological antivirals for treatment of adenovirus infections. Antiviral therapy\| PubMed ID: 27032991	2016