Paul R. Knight

Department of Anesthesiology, University at Buffalo, State University of New York

Affiliated withUniversity at Buffalo, State University of New York Veterans Admistration Western New York Healthcare System

Research Area

Medicine

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 12	2017

Other Publications

Article	Year
The evolution of isolated bilateral lung contusion from blunt chest trauma in rats: cellular and cytokine responses. Shock (Augusta, Ga.)\| PubMed ID: 16044083	2005
Anesthesiology residency programs for physician scientists. Anesthesiology\| PubMed ID: 16394681	2006
Statistical prediction of the type of gastric aspiration lung injury based on early cytokine/chemokine profiles. Anesthesiology\| PubMed ID: 16394693	2006
A rat model for isolated bilateral lung contusion from blunt chest trauma. Anesthesia and analgesia\| PubMed ID: 16244015	2005
Halothane potentiation of hydrogen peroxide-induced inhibition of surfactant synthesis: the role of type II cell energy status. Anesthesia and analgesia\| PubMed ID: 11916801	2002
An unexplained death: Hannah Greener and chloroform. Anesthesiology\| PubMed ID: 11981167	2002
Expression of neuron-associated tumor necrosis factor alpha in the brain is increased during persistent pain. Regional anesthesia and pain medicine\| PubMed ID: 12132059	2002
Total extracellular surfactant is increased but abnormal in a rat model of gram-negative bacterial pneumonia. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 12169586	2002
Modulation of angiotensin II responses in sympathetic neurons by cytosolic calcium. Hypertension\| PubMed ID: 12511530	2003
The effects of Escherichia coli capsule, O-antigen, host neutrophils, and complement in a rat model of Gram-negative pneumonia. FEMS microbiology letters\| PubMed ID: 14553933	2003
Human neutrophil chemotaxis is modulated by capsule and O antigen from an extraintestinal pathogenic Escherichia coli strain. Infection and immunity\| PubMed ID: 14573665	2003
Development of a sensitive microarray immunoassay and comparison with standard enzyme-linked immunoassay for cytokine analysis. Shock (Augusta, Ga.)\| PubMed ID: 14676680	2004
Gastric acid and particulate aspiration injury inhibits pulmonary bacterial clearance. Critical care medicine\| PubMed ID: 15090957	2004
Bacterial clearance and cytokine profiles in a murine model of postsurgical nosocomial pneumonia. Clinical and diagnostic laboratory immunology\| PubMed ID: 15242950	2004
Progressive, severe lung injury secondary to the interaction of insults in gastric aspiration. Experimental lung research\| PubMed ID: 15371091	2004
Mechanisms of angiotensin II-mediated decreases in intraneuronal Ca2+ in calcium-loaded stellate ganglion neurons. Hypertension\| PubMed ID: 15642775	2005
The dissipation of neuropathic pain paradoxically involves the presence of tumor necrosis factor-alpha (TNF). Neuropharmacology\| PubMed ID: 15721177	2005
Surfactant alterations in acute inflammatory lung injury from aspiration of acid and gastric particulates. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 15757954	2005
Acid and particulate-induced aspiration lung injury in mice: importance of MCP-1. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 15778247	2005
E. coli virulence factor hemolysin induces neutrophil apoptosis and necrosis/lysis in vitro and necrosis/lysis and lung injury in a rat pneumonia model. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 15805136	2005
Discrimination of resident and infiltrated alveolar macrophages by flow cytometry in influenza A virus-infected mice. Experimental lung research\| PubMed ID: 15962712	2005
Serine antiproteinase administration preserves innate superoxide dismutase levels after acid aspiration and hyperoxia but does not decrease lung injury. Anesthesia and analgesia\| PubMed ID: 15976234	2005
Inclusion of sevoflurane in cardioplegia reduces neutrophil activity during cardiopulmonary bypass. Journal of cardiothoracic and vascular anesthesia\| PubMed ID: 16458215	2006
Antinociception mediated by alpha(2)-adrenergic activation involves increasing tumor necrosis factor alpha (TNFalpha) expression and restoring TNFalpha and alpha(2)-adrenergic inhibition of ... Neuropharmacology\| PubMed ID: 17055005	2007
Acid aspiration-induced lung inflammation and injury are exacerbated in NADPH oxidase-deficient mice. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 17114280	2007
Surfactant dysfunction and lung injury due to the E. coli virulence factor hemolysin in a rat pneumonia model. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 17341765	2007
The role of alveolar macrophages in the pathogenesis of aspiration pneumonitis. Immunological investigations\| PubMed ID: 17691026	2007
Capsule and O-antigen from an extraintestinal isolate of Escherichia coli modulate cytokine levels in rat macrophages in vitro and in a rat model of pneumonia. Experimental lung research\| PubMed ID: 17849261	2007
Surfactant dysfunction in lung contusion with and without superimposed gastric aspiration in a rat model. Shock (Augusta, Ga.)\| PubMed ID: 18323743	2008
Proteomic analysis of the balance between survival and cell death responses in cisplatin-mediated ototoxicity. Journal of proteome research\| PubMed ID: 18578524	2008
Pharmacotherapy of acute lung injury and acute respiratory distress syndrome. Current medicinal chemistry\| PubMed ID: 18691048	2008
Tissue inhibitor of metalloproteinase-1 modulates allergic lung inflammation in murine asthma. Clinical immunology (Orlando, Fla.)\| PubMed ID: 18955015	2009
Lung contusion: inflammatory mechanisms and interaction with other injuries. Shock (Augusta, Ga.)\| PubMed ID: 19174738	2009
Superimposed gastric aspiration increases the severity of inflammation and permeability injury in a rat model of lung contusion. The Journal of surgical research\| PubMed ID: 19515386	2009
Predictive modeling and inflammatory biomarkers in rats with lung contusion and gastric aspiration. The Journal of trauma\| PubMed ID: 20009665	2009
Biomarkers in the diagnosis of aspiration syndromes. Expert review of molecular diagnostics\| PubMed ID: 20370588	2010
Gold nanorod delivery of an ssRNA immune activator inhibits pandemic H1N1 influenza viral replication. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 20498074	2010
Doxorubicin-conjugated quantum dots to target alveolar macrophages and inflammation. Nanomedicine : nanotechnology, biology, and medicine\| PubMed ID: 20887813	2011
Aspiration-induced lung injury. Critical care medicine\| PubMed ID: 21263315	2011
Diagnostic use of serum procalcitonin levels in pulmonary aspiration syndromes. Critical care medicine\| PubMed ID: 21283001	2011
Role of macrophage chemoattractant protein-1 in acute inflammation after lung contusion. American journal of respiratory cell and molecular biology\| PubMed ID: 22281985	2012
Increasing TNF levels solely in the rat hippocampus produces persistent pain-like symptoms. Pain\| PubMed ID: 22770843	2012
The receptor for advanced glycation end products and acute lung injury/acute respiratory distress syndrome. Intensive care medicine\| PubMed ID: 22777515	2012
Effect of high advanced glycation end-product diet on pulmonary inflammatory response and pulmonary function following gastric aspiration. Shock (Augusta, Ga.)\| PubMed ID: 23143059	2012
NADPH oxidase and Nrf2 regulate gastric aspiration-induced inflammation and acute lung injury. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 23296708	2013
Role of pulmonary artery reactivity and nitric oxide in injury and inflammation following lung contusion. Shock (Augusta, Ga.)\| PubMed ID: 23364426	2013
Monocyte- and macrophage-targeted NADPH oxidase mediates antifungal host defense and regulation of acute inflammation in mice. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 23509361	2013
Interkingdom signaling induces Streptococcus pneumoniae biofilm dispersion and transition from asymptomatic colonization to disease. mBio\| PubMed ID: 23882016	2013
Low pH environmental stress inhibits LPS and LTA-stimulated proinflammatory cytokine production in rat alveolar macrophages. BioMed research international\| PubMed ID: 24288685	2013
Dietary advanced glycation end-products, its pulmonary receptor, and high mobility group box 1 in aspiration lung injury. The Journal of surgical research\| PubMed ID: 24814199	2014
Chronic constriction injury-induced nociception is relieved by nanomedicine-mediated decrease of rat hippocampal tumor necrosis factor. Pain\| PubMed ID: 25851457	2015
Halothane modulates the type i interferon response to influenza and minimizes the risk of secondary bacterial pneumonia through maintenance of neutrophil recruitment in an animal model. Anesthesiology\| PubMed ID: 26120770	2015
The Effect of Lipopolysaccharide on Ischemic-Reperfusion Injury of Heart: A Double Hit Model of Myocardial Ischemia and Endotoxemia. Journal of cardiovascular and thoracic research\| PubMed ID: 26430494	2015
Directed vaccination against pneumococcal disease. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 27274071	2016