Jacqueline Cloos

Department of Pediatric Oncology/Hematology, VU University medical center

Affiliated withVU University medical center

Research Area

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 25	2016
Publication title Cited by 36	2018

Other Publications

Article	Year
The effect of G-CSF on the in vitro cytotoxicity of cytarabine and fludarabine in the FLAG combination in pediatric acute myeloid leukemia. International journal of oncology\| PubMed ID: 15547723	2004
Acquired resistance to chloroquine in human CEM T cells is mediated by multidrug resistance-associated protein 1 and provokes high levels of cross-resistance to glucocorticoids. Arthritis and rheumatism\| PubMed ID: 16447232	2006
Microarray analysis of bleomycin-exposed lymphoblastoid cells for identifying cancer susceptibility genes. Molecular cancer research : MCR\| PubMed ID: 16513838	2006
Stability and prognostic influence of FLT3 mutations in paired initial and relapsed AML samples. Leukemia\| PubMed ID: 16642044	2006
Sulfasalazine sensitises human monocytic/macrophage cells for glucocorticoids by upregulation of glucocorticoid receptor alpha and glucocorticoid induced apoptosis. Annals of the rheumatic diseases\| PubMed ID: 17267514	2007
Methylenetetrahydrofolate reductase (MTHFR) C677T and thymidylate synthase promoter (TSER) polymorphisms in Indonesian children with and without leukemia. Leukemia research\| PubMed ID: 17395259	2008
Molecular basis of bortezomib resistance: proteasome subunit beta5 (PSMB5) gene mutation and overexpression of PSMB5 protein. Blood\| PubMed ID: 18565852	2008
Integrated genomics identifies five medulloblastoma subtypes with distinct genetic profiles, pathway signatures and clinicopathological features. PloS one\| PubMed ID: 18769486	2008
Role of tyrosine phosphatase inhibitors in cancer treatment with emphasis on SH2 domain-containing tyrosine phosphatases (SHPs). Anti-cancer agents in medicinal chemistry\| PubMed ID: 19199865	2009
Attenuated AMPA receptor expression allows glioblastoma cell survival in glutamate-rich environment. PloS one\| PubMed ID: 19536293	2009
FLT3 and KIT mutated pediatric acute myeloid leukemia (AML) samples are sensitive in vitro to the tyrosine kinase inhibitor SU11657. Leukemia research\| PubMed ID: 20435347	2010
Strategies for the analysis of in vitro radiation sensitivity and prediction of interaction with potential radiation modifying agents. International journal of radiation biology\| PubMed ID: 20470196	2010
High-frequency type I/II mutational shifts between diagnosis and relapse are associated with outcome in pediatric AML: implications for personalized medicine. Blood\| PubMed ID: 20592250	2010
In silico analysis of kinase expression identifies WEE1 as a gatekeeper against mitotic catastrophe in glioblastoma. Cancer cell\| PubMed ID: 20832752	2010
Evaluation of gene expression signatures predictive of cytogenetic and molecular subtypes of pediatric acute myeloid leukemia. Haematologica\| PubMed ID: 20971820	2011
Down-regulation of miR-101 in endothelial cells promotes blood vessel formation through reduced repression of EZH2. PloS one\| PubMed ID: 21297974	2011
miR-101 is down-regulated in glioblastoma resulting in EZH2-induced proliferation, migration, and angiogenesis. Oncotarget\| PubMed ID: 21321380	2010
Cell sensitivity assays: the MTT assay. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 21516412	2011
Integrative analysis of type-I and type-II aberrations underscores the genetic heterogeneity of pediatric acute myeloid leukemia. Haematologica\| PubMed ID: 21791472	2011
Proteasome-based mechanisms of intrinsic and acquired bortezomib resistance in non-small cell lung cancer. Biochemical pharmacology\| PubMed ID: 22027222	2012
PARP inhibition sensitizes childhood high grade glioma, medulloblastoma and ependymoma to radiation. Oncotarget\| PubMed ID: 22184287	2011
Myeloid Antigen Expression in Childhood Acute Lymphoblastic Leukemia and Its Relevance for Clinical Outcome in Indonesian ALL-2006 Protocol. Journal of oncology\| PubMed ID: 23227046	2012
Overcoming bortezomib resistance in human B cells by anti-CD20/rituximab-mediated complement-dependent cytotoxicity and epoxyketone-based irreversible proteasome inhibitors. Experimental hematology & oncology\| PubMed ID: 23305345	2013
Randomized double blind trial of ciprofloxacin prophylaxis during induction treatment in childhood acute lymphoblastic leukemia in the WK-ALL protocol in Indonesia. Journal of blood medicine\| PubMed ID: 23403504	2013
Proteasome inhibitors in acute leukemia. Expert review of anticancer therapy\| PubMed ID: 23477519	2013
Higher ratio immune versus constitutive proteasome level as novel indicator of sensitivity of pediatric acute leukemia cells to proteasome inhibitors. Haematologica\| PubMed ID: 24056819	2013
High resolution SNP array profiling identifies variability in retinoblastoma genome stability. Genes, chromosomes & cancer\| PubMed ID: 24249257	2014
Interferon-γ-induced upregulation of immunoproteasome subunit assembly overcomes bortezomib resistance in human hematological cell lines. Journal of hematology & oncology\| PubMed ID: 24418325	2014
Pre-B-cell leukemia homeobox interacting protein 1 is overexpressed in astrocytoma and promotes tumor cell growth and migration. Neuro-oncology\| PubMed ID: 24470547	2014
Anti-leukemic activity and mechanisms underlying resistance to the novel immunoproteasome inhibitor PR-924. Biochemical pharmacology\| PubMed ID: 24552657	2014
RB1 mutation spectrum in a comprehensive nationwide cohort of retinoblastoma patients. Journal of medical genetics\| PubMed ID: 24688104	2014
Antileukemic activity and mechanism of drug resistance to the marine Salinispora tropica proteasome inhibitor salinosporamide A (Marizomib). Molecular pharmacology\| PubMed ID: 24737138	2014
Relevance of leukemic stem cells in acute myeloid leukemia: heterogeneity and influence on disease monitoring, prognosis and treatment design. Expert review of hematology\| PubMed ID: 25242511	2014
Pre-mRNA splicing in cancer: the relevance in oncogenesis, treatment and drug resistance. Expert opinion on drug metabolism & toxicology\| PubMed ID: 25495223	2015
Molecular basis of resistance to proteasome inhibitors in hematological malignancies. Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy\| PubMed ID: 25670156	2015
Gene expression profiles associated with pediatric relapsed AML. PloS one\| PubMed ID: 25849371	2015
Methotrexate resistance in relation to treatment outcome in childhood acute lymphoblastic leukemia. Journal of hematology & oncology\| PubMed ID: 26022503	2015
Loss of photoreceptorness and gain of genomic alterations in retinoblastoma reveal tumor progression. EBioMedicine\| PubMed ID: 26288838	2015
Multifactorial resistance to aminopeptidase inhibitor prodrug CHR2863 in myeloid leukemia cells: down-regulation of carboxylesterase 1, drug sequestration in lipid droplets and pro-survival ... Oncotarget\| PubMed ID: 26496029	2016
Folylpolyglutamate synthetase splicing alterations in acute lymphoblastic leukemia are provoked by methotrexate and other chemotherapeutics and mediate chemoresistance. International journal of cancer\| PubMed ID: 26547381	2016
Clinical Impact of Additional Cytogenetic Aberrations, cKIT and RAS Mutations, and Treatment Elements in Pediatric t(8;21)-AML: Results From an International Retrospective Study by the Inter... Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 26573082	2015
miR expression profiling at diagnosis predicts relapse in pediatric precursor B-cell acute lymphoblastic leukemia. Genes, chromosomes & cancer\| PubMed ID: 26684414	2016
Pharmacodynamic monitoring of (immuno)proteasome inhibition during bortezomib treatment of a critically ill patient with lupus nephritis and myocarditis. Lupus science & medicine\| PubMed ID: 26719810	2015
Exosomes Secreted by Apoptosis-Resistant Acute Myeloid Leukemia (AML) Blasts Harbor Regulatory Network Proteins Potentially Involved in Antagonism of Apoptosis. Molecular & cellular proteomics : MCP\| PubMed ID: 26801919	2016
How to assess minimal residual disease in pediatric and adult acute myeloid leukemia? Translational pediatrics\| PubMed ID: 26835296	2013
A chemical screen for medulloblastoma identifies quercetin as a putative radiosensitizer. Oncotarget\| PubMed ID: 26967057	2016
The association of aberrant folylpolyglutamate synthetase splicing with ex vivo methotrexate resistance and clinical outcome in childhood acute lymphoblastic leukemia. Haematologica\| PubMed ID: 27036162	2016
A Meta-Analysis of Retinoblastoma Copy Numbers Refines the List of Possible Driver Genes Involved in Tumor Progression. PloS one\| PubMed ID: 27115612	2016
Somatic genomic alterations in retinoblastoma beyond RB1 are rare and limited to copy number changes. Scientific reports\| PubMed ID: 27126562	2016
Exocytosis of polyubiquitinated proteins in bortezomib-resistant leukemia cells: a role for MARCKS in acquired resistance to proteasome inhibitors. Oncotarget\| PubMed ID: 27542283	2016
Proteasome subunit expression analysis and chemosensitivity in relapsed paediatric acute leukaemia patients receiving bortezomib-containing chemotherapy. Journal of hematology & oncology\| PubMed ID: 27599459	2016
Genomic landscape of retinoblastoma in Rbp130mice resembles human retinoblastoma. Genes, chromosomes & cancer\| PubMed ID: 27750399	2017
Leukemic stem cells: identification and clinical application. International journal of hematology\| PubMed ID: 28357569	2017
The interference of genetic associations in establishing the prognostic value of the immunophenotype in acute myeloid leukemia. Cytometry. Part B, Clinical cytometry\| PubMed ID: 28646564	2018
Bortezomib resistance in multiple myeloma is associated with increased serine synthesis. Cancer & metabolism\| PubMed ID: 28855983	2017
(Immuno)proteasomes as therapeutic target in acute leukemia. Cancer metastasis reviews\| PubMed ID: 29071527	2017
Leukaemic stem cell load at diagnosis predicts the development of relapse in young acute myeloid leukaemia patients. British journal of haematology\| PubMed ID: 29076143	2017
Trimethylation of H3K27 during human cerebellar development in relation to medulloblastoma. Oncotarget\| PubMed ID: 29108280	2017
Positioning of proteasome inhibitors in therapy of solid malignancies. Cancer chemotherapy and pharmacology\| PubMed ID: 29184971	2018
Minimal/measurable residual disease in AML: consensus document from ELN MRD Working Party. Blood\| PubMed ID: 29330221	2018
Proteasome inhibition and mechanism of resistance to a synthetic, library-based hexapeptide. Investigational new drugs\| PubMed ID: 29442210	2018