Gillian Farnie

Institute of Cancer Sciences, University of Manchester

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 20	2016

Other Publications

Article	Year
The mitogenic action of insulin-like growth factor I in normal human mammary epithelial cells requires the epidermal growth factor receptor tyrosine kinase. The Journal of biological chemistry\| PubMed ID: 14593113	2004
Isoindolinone-based inhibitors of the MDM2-p53 protein-protein interaction. Bioorganic & medicinal chemistry letters\| PubMed ID: 15713419	2005
Small-molecule inhibitors of the MDM2-p53 protein-protein interaction based on an isoindolinone scaffold. Journal of medicinal chemistry\| PubMed ID: 17034127	2006
Novel cell culture technique for primary ductal carcinoma in situ: role of Notch and epidermal growth factor receptor signaling pathways. Journal of the National Cancer Institute\| PubMed ID: 17440163	2007
Mammary stem cells and breast cancer--role of Notch signalling. Stem cell reviews\| PubMed ID: 17873349	2007
Prolactin receptor antagonism reduces the clonogenic capacity of breast cancer cells and potentiates doxorubicin and paclitaxel cytotoxicity. Breast cancer research : BCR\| PubMed ID: 18681966	2008
Are stem-like cells responsible for resistance to therapy in breast cancer? Breast disease\| PubMed ID: 19029627	2008
Resistance to endocrine therapy: are breast cancer stem cells the culprits? Journal of mammary gland biology and neoplasia\| PubMed ID: 19252972	2009
Regulation of breast cancer stem cell activity by signaling through the Notch4 receptor. Cancer research\| PubMed ID: 20068161	2010
Breast cancer stem cells: something out of notching? Cancer research\| PubMed ID: 21045140	2010
Breast cancer stem cells and their role in resistance to endocrine therapy. Hormones & cancer\| PubMed ID: 21761332	2011
P-Cadherin is Co-Expressed with Cd44 and Cd49f and Mediates Stem Cell Properties in Basal-Like Breast Cancer. Stem cells (Dayton, Ohio)\| PubMed ID: 22389315	2012
A detailed mammosphere assay protocol for the quantification of breast stem cell activity. Journal of mammary gland biology and neoplasia\| PubMed ID: 22665270	2012
Targeting CXCR1/2 significantly reduces breast cancer stem cell activity and increases the efficacy of inhibiting HER2 via HER2-dependent and -independent mechanisms. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 23149820	2013
Combined inhibition of ErbB1/2 and Notch receptors effectively targets breast ductal carcinoma in situ (DCIS) stem/progenitor cell activity regardless of ErbB2 status. PloS one\| PubMed ID: 23457626	2013
Recent advances reveal IL-8 signaling as a potential key to targeting breast cancer stem cells. Breast cancer research : BCR\| PubMed ID: 24041156	2013
Lapatinib inhibits stem/progenitor proliferation in preclinical in vitro models of ductal carcinoma in situ (DCIS). Cell cycle (Georgetown, Tex.)\| PubMed ID: 24247151	2014
A differential role for CXCR4 in the regulation of normal versus malignant breast stem cell activity. Oncotarget\| PubMed ID: 24583601	2014
Focal adhesion kinase and Wnt signaling regulate human ductal carcinoma in situ stem cell activity and response to radiotherapy. Stem cells (Dayton, Ohio)\| PubMed ID: 25187396	2015
Anti-estrogen Resistance in Human Breast Tumors Is Driven by JAG1-NOTCH4-Dependent Cancer Stem Cell Activity. Cell reports\| PubMed ID: 26387946	2015
High mitochondrial mass identifies a sub-population of stem-like cancer cells that are chemo-resistant. Oncotarget\| PubMed ID: 26421710	2015
Three-dimensional modelling identifies novel genetic dependencies associated with breast cancer progression in the isogenic MCF10 model. The Journal of pathology\| PubMed ID: 27512948	2016
Patient-derived Mammosphere and Xenograft Tumour Initiation Correlates with Progression to Metastasis. Journal of mammary gland biology and neoplasia\| PubMed ID: 27680982	2016
Erratum to: Patient-Derived Mammosphere and Xenograft Tumour Initiation Correlates with Progression to Metastasis. Journal of mammary gland biology and neoplasia\| PubMed ID: 27815673	2016