Doris Kretzschmar

Oregon Institute of Occupational Health Sciences, Oregon Health & Sciences University

Affiliated withOregon Health & Sciences University

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 35	2016

Other Publications

Article	Year
The neurodegeneration mutant löchrig interferes with cholesterol homeostasis and Appl processing. The EMBO journal\| PubMed ID: 12456644	2002
Deregulation of the Egfr/Ras signaling pathway induces age-related brain degeneration in the Drosophila mutant vap. Molecular biology of the cell\| PubMed ID: 12529440	2003
Placental failure and impaired vasculogenesis result in embryonic lethality for neuropathy target esterase-deficient mice. Molecular and cellular biology\| PubMed ID: 14749382	2004
Age-dependent neurodegeneration and Alzheimer-amyloid plaque formation in transgenic Drosophila. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 15102905	2004
The Drosophila carbonyl reductase sniffer prevents oxidative stress-induced neurodegeneration. Current biology : CB\| PubMed ID: 15120069	2004
Glial and neuronal expression of polyglutamine proteins induce behavioral changes and aggregate formation in Drosophila. Glia\| PubMed ID: 15390099	2005
Disruption of the MAP1B-related protein FUTSCH leads to changes in the neuronal cytoskeleton, axonal transport defects, and progressive neurodegeneration in Drosophila. Molecular biology of the cell\| PubMed ID: 15772149	2005
Loss of Swiss cheese/neuropathy target esterase activity causes disruption of phosphatidylcholine homeostasis and neuronal and glial death in adult Drosophila. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 15772346	2005
Neurodegenerative mutants in Drosophila: a means to identify genes and mechanisms involved in human diseases? Invertebrate neuroscience : IN\| PubMed ID: 16187075	2005
Optomotor-blind expression in glial cells is required for correct axonal projection across the Drosophila inner optic chiasm. Developmental biology\| PubMed ID: 18234176	2008
Swiss Cheese, a protein involved in progressive neurodegeneration, acts as a noncanonical regulatory subunit for PKA-C3. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 18945896	2008
Neurotoxic effects induced by the Drosophila amyloid-beta peptide suggest a conserved toxic function. Neurobiology of disease\| PubMed ID: 19049874	2009
Swiss cheese et allii, some of the first neurodegenerative mutants isolated in Drosophila. Journal of neurogenetics\| PubMed ID: 19132601	2009
Identification of novel 1,4-benzoxazine compounds that are protective in tissue culture and in vivo models of neurodegeneration. Journal of neuroscience research\| PubMed ID: 20143421	2010
The circadian clock gene period extends healthspan in aging Drosophila melanogaster. Aging\| PubMed ID: 20157575	2009
Alzheimer's disease and tauopathy studies in flies and worms. Neurobiology of disease\| PubMed ID: 20302939	2010
A translational continuum of model systems for evaluating treatment strategies in Alzheimer's disease: isradipine as a candidate drug. Disease models & mechanisms\| PubMed ID: 21596710	2011
Analysis of amyloid precursor protein function in Drosophila melanogaster. Experimental brain research\| PubMed ID: 21912928	2012
Drosophila GGA model: an ultimate gateway to GGA analysis. Traffic (Copenhagen, Denmark)\| PubMed ID: 21923734	2011
Loss of circadian clock accelerates aging in neurodegeneration-prone mutants. Neurobiology of disease\| PubMed ID: 22227001	2012
Amyloid precursor proteins are protective in Drosophila models of progressive neurodegeneration. Neurobiology of disease\| PubMed ID: 22266106	2012
Increased RhoA prenylation in the loechrig (loe) mutant leads to progressive neurodegeneration. PloS one\| PubMed ID: 22970217	2012
β-secretase cleavage of the fly amyloid precursor protein is required for glial survival. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 23152602	2012
Mutations in γ adducin are associated with inherited cerebral palsy. Annals of neurology\| PubMed ID: 23836506	2013
Organophosphate-induced changes in the PKA regulatory function of Swiss Cheese/NTE lead to behavioral deficits and neurodegeneration. PloS one\| PubMed ID: 24558370	2014
Increased actin polymerization and stabilization interferes with neuronal function and survival in the AMPKγ mutant Loechrig. PloS one\| PubMed ID: 24587072	2014
Loss of Tau results in defects in photoreceptor development and progressive neuronal degeneration in Drosophila. Developmental neurobiology\| PubMed ID: 24909306	2014
Loss-of-function mutations in PNPLA6 encoding neuropathy target esterase underlie pubertal failure and neurological deficits in Gordon Holmes syndrome. The Journal of clinical endocrinology and metabolism\| PubMed ID: 25033069	2014
Relationships between the circadian system and Alzheimer's disease-like symptoms in Drosophila. PloS one\| PubMed ID: 25171136	2014
Manipulations of amyloid precursor protein cleavage disrupt the circadian clock in aging Drosophila. Neurobiology of disease\| PubMed ID: 25766673	2015
Glial expression of Swiss cheese (SWS), the Drosophila orthologue of neuropathy target esterase (NTE), is required for neuronal ensheathment and function. Disease models & mechanisms\| PubMed ID: 26634819	2016
Analysis of Amyloid Precursor Protein Function in Drosophila melanogaster. Frontiers in molecular neuroscience\| PubMed ID: 27507933	2016
Amyloid Precursor Proteins Are Dynamically Trafficked and Processed during Neuronal Development. Frontiers in molecular neuroscience\| PubMed ID: 27932950	2016