Lisa M. Coussens

Cell, Oregon Health & Science University

Affiliated withOregon Health & Science University

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 6	2017

Other Publications

Article	Year
Matrix metalloproteinase inhibitors and cancer: trials and tribulations. Science (New York, N.Y.)\| PubMed ID: 11923519	2002
RECKing MMP function: implications for cancer development. Trends in cell biology\| PubMed ID: 12062160	2002
MMP9 potentiates pulmonary metastasis formation. Cancer cell\| PubMed ID: 12398887	2002
Inflammation and cancer. Nature\| PubMed ID: 12490959	2002
Epithelial carcinogenesis: dynamic interplay between neoplastic cells and their microenvironment. Differentiation; research in biological diversity\| PubMed ID: 12492502	2002
Immune enhancement of skin carcinogenesis by CD4+ T cells. The Journal of experimental medicine\| PubMed ID: 12695493	2003
The tumor microenvironment: a critical determinant of neoplastic evolution. European journal of cell biology\| PubMed ID: 14703010	2003
TIMP-1 alters susceptibility to carcinogenesis. Cancer research\| PubMed ID: 14871825	2004
Stromal matrix metalloproteinase-9 regulates the vascular architecture in neuroblastoma by promoting pericyte recruitment. Cancer research\| PubMed ID: 14996727	2004
Matrix metalloproteinase-2 and -9 expression increases in Mycoplasma-infected airways but is not required for microvascular remodeling. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 15075248	2004
Cancer: an inflammatory link. Nature\| PubMed ID: 15385993	2004
Early neoplastic progression is complement independent. Neoplasia (New York, N.Y.)\| PubMed ID: 15720803	2004
Soluble mediators of inflammation during tumor development. Advances in cancer research\| PubMed ID: 15797447	2005
The contribution of bone marrow-derived cells to the tumor vasculature in neuroblastoma is matrix metalloproteinase-9 dependent. Cancer research\| PubMed ID: 15833851	2005
De novo carcinogenesis promoted by chronic inflammation is B lymphocyte dependent. Cancer cell\| PubMed ID: 15894262	2005
Paradoxical roles of the immune system during cancer development. Nature reviews. Cancer\| PubMed ID: 16397525	2006
Inflammation, proteases and cancer. European journal of cancer (Oxford, England : 1990)\| PubMed ID: 16524717	2006
The inflammatory tumor microenvironment and its impact on cancer development. Contributions to microbiology\| PubMed ID: 16627962	2006
A selective activity-based probe for the papain family cysteine protease dipeptidyl peptidase I/cathepsin C. Journal of the American Chemical Society\| PubMed ID: 16637611	2006
Analysis of immune cell infiltrates during squamous carcinoma development. The journal of investigative dermatology. Symposium proceedings\| PubMed ID: 17069009	2006
Tumor progression and metastasis from genetic to microenvironmental determinants: a workshop of the tumor progression and metastasis NIH study section in honor of Dr. Martin L. Padarathsingh... Cancer biology & therapy\| PubMed ID: 17224636	2006
Immune cells as anti-cancer therapeutic targets and tools. Journal of cellular biochemistry\| PubMed ID: 17265430	2007
Humoral immunity, inflammation and cancer. Current opinion in immunology\| PubMed ID: 17276050	2007
IKKalpha at the crossroads of inflammation and metastasis. Cell\| PubMed ID: 17418780	2007
Type I collagen is a genetic modifier of matrix metalloproteinase 2 in murine skeletal development. Developmental dynamics : an official publication of the American Association of Anatomists\| PubMed ID: 17440987	2007
Hu/Mu ProtIn oligonucleotide microarray: dual-species array for profiling protease and protease inhibitor gene expression in tumors and their microenvironment. Molecular cancer research : MCR\| PubMed ID: 17510311	2007
Distinctive features of angiogenesis and lymphangiogenesis determine their functionality during de novo tumor development. Cancer research\| PubMed ID: 17545601	2007
Inflammation and breast cancer. Balancing immune response: crosstalk between adaptive and innate immune cells during breast cancer progression. Breast cancer research : BCR\| PubMed ID: 17705880	2007
Tissue inhibitor of metalloproteinases-1 promotes liver metastasis by induction of hepatocyte growth factor signaling. Cancer research\| PubMed ID: 17875701	2007
Tumor stroma and regulation of cancer development. Annual review of pathology\| PubMed ID: 18039110	2006
Immune cells as mediators of solid tumor metastasis. Cancer metastasis reviews\| PubMed ID: 18066650	2008
The initial steps of ovarian cancer cell metastasis are mediated by MMP-2 cleavage of vitronectin and fibronectin. The Journal of clinical investigation\| PubMed ID: 18340378	2008
Polarized immune responses differentially regulate cancer development. Immunological reviews\| PubMed ID: 18363999	2008
Genetic and cellular mechanisms of oncogenesis. Current opinion in genetics & development\| PubMed ID: 18440220	2008
Inflaming gastrointestinal oncogenic programming. Cancer cell\| PubMed ID: 18598939	2008
Three-dimensional visualization of blood and lymphatic vasculature in tissue whole mounts using confocal microscopy. Current protocols in cytometry\| PubMed ID: 18770816	2005
Development of an optimized activatable MMP-14 targeted SPECT imaging probe. Bioorganic & medicinal chemistry\| PubMed ID: 19109023	2009
Delineating protease functions during cancer development. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 19377975	2009
CD4(+) T cells regulate pulmonary metastasis of mammary carcinomas by enhancing protumor properties of macrophages. Cancer cell\| PubMed ID: 19647220	2009
Collagen-based cell migration models in vitro and in vivo. Seminars in cell & developmental biology\| PubMed ID: 19682592	2009
Optical imaging of the peri-tumoral inflammatory response in breast cancer. Journal of translational medicine\| PubMed ID: 19906309	2009
Lymphocytes in cancer development: polarization towards pro-tumor immunity. Cytokine & growth factor reviews\| PubMed ID: 20005150	2010
FcRgamma activation regulates inflammation-associated squamous carcinogenesis. Cancer cell\| PubMed ID: 20138013	2010
Stromal regulation of vessel stability by MMP14 and TGFbeta. Disease models & mechanisms\| PubMed ID: 20223936	2010
Unimpeded skin carcinogenesis in K14-HPV16 transgenic mice deficient for plasminogen activator inhibitor. International journal of cancer\| PubMed ID: 20232379	2011
Cancer and inflammation: promise for biologic therapy. Journal of immunotherapy (Hagerstown, Md. : 1997)\| PubMed ID: 20386472	2010
Interactions between lymphocytes and myeloid cells regulate pro- versus anti-tumor immunity. Cancer metastasis reviews\| PubMed ID: 20405169	2010
Macrophage expression of hypoxia-inducible factor-1 alpha suppresses T-cell function and promotes tumor progression. Cancer research\| PubMed ID: 20841473	2010
Receptor tyrosine kinase signaling favors a protumorigenic state in breast cancer cells by inhibiting the adaptive immune response. Cancer research\| PubMed ID: 20924104	2010
Leukocytes in mammary development and cancer. Cold Spring Harbor perspectives in biology\| PubMed ID: 21123394	2011
The tumor-immune microenvironment and response to radiation therapy. Journal of mammary gland biology and neoplasia\| PubMed ID: 21161342	2010
Histamine restricts cancer: nothing to sneeze at. Nature medicine\| PubMed ID: 21217680	2011
Leukocytes as paracrine regulators of metastasis and determinants of organ-specific colonization. International journal of cancer. Journal international du cancer\| PubMed ID: 21387299	2011
Protective role of cathepsin L in mouse skin carcinogenesis. Molecular carcinogenesis\| PubMed ID: 21538579	2012
B regulatory cells and the tumor-promoting actions of TNF-α during squamous carcinogenesis. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 21670304	2011
MRI of tumor-associated macrophages with clinically applicable iron oxide nanoparticles. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 21791632	2011
Leukocyte composition of human breast cancer. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 21825174	2012
Leukocyte complexity predicts breast cancer survival and functionally regulates response to chemotherapy. Cancer discovery\| PubMed ID: 22039576	2011
Immune microenvironments in solid tumors: new targets for therapy. Genes & development\| PubMed ID: 22190457	2011
Differential macrophage programming in the tumor microenvironment. Trends in immunology\| PubMed ID: 22277903	2012
Respiratory Homeostasis and Exploitation of the Immune System for Lung Cancer Vaccines. US oncology\| PubMed ID: 22368692	2009
Tumor microenvironment complexity: emerging roles in cancer therapy. Cancer research\| PubMed ID: 22414581	2012
Accessories to the crime: functions of cells recruited to the tumor microenvironment. Cancer cell\| PubMed ID: 22439926	2012
MR imaging of tumor-associated macrophages. Oncoimmunology\| PubMed ID: 22754769	2012
Neutralizing tumor-promoting chronic inflammation: a magic bullet? Science (New York, N.Y.)\| PubMed ID: 23329041	2013
B cells and their mediators as targets for therapy in solid tumors. Experimental cell research\| PubMed ID: 23499742	2013
Some DCs are "B"etter. Immunity\| PubMed ID: 23601679	2013
Tumor-infiltrating regulatory T cells inhibit endogenous cytotoxic T cell responses to lung adenocarcinoma. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 23851682	2013
Cathepsin C is a tissue-specific regulator of squamous carcinogenesis. Genes & development\| PubMed ID: 24065739	2013
Dendritic cells, inflammation, and breast cancer. Cancer journal (Sudbury, Mass.)\| PubMed ID: 24270350	2013
Poker face no more: cancer recurrence reveals its hand. Nature medicine\| PubMed ID: 24309652	2013
CSF1R inhibition delays cervical and mammary tumor growth in murine models by attenuating the turnover of tumor-associated macrophages and enhancing infiltration by CD8(+) T cells. Oncoimmunology\| PubMed ID: 24498562	2013
A Listeria vaccine and depletion of T-regulatory cells activate immunity against early stage pancreatic intraepithelial neoplasms and prolong survival of mice. Gastroenterology\| PubMed ID: 24607504	2014
B cells regulate macrophage phenotype and response to chemotherapy in squamous carcinomas. Cancer cell\| PubMed ID: 24909985	2014
Mammary gland involution as an immunotherapeutic target for postpartum breast cancer. Journal of mammary gland biology and neoplasia\| PubMed ID: 24952477	2014
Manipulating microRNAs to regulate macrophage polarization in gliomas. Journal of the National Cancer Institute\| PubMed ID: 25136034	2014
Duality of the immune response in cancer: lessons learned from skin. The Journal of investigative dermatology\| PubMed ID: 25302470	2014
Macrophage IL-10 blocks CD8+ T cell-dependent responses to chemotherapy by suppressing IL-12 expression in intratumoral dendritic cells. Cancer cell\| PubMed ID: 25446896	2014
TH2-Polarized CD4(+) T Cells and Macrophages Limit Efficacy of Radiotherapy. Cancer immunology research\| PubMed ID: 25716473	2015
Macrophages and therapeutic resistance in cancer. Cancer cell\| PubMed ID: 25858805	2015
Myeloid Cells as Targets for Therapy in Solid Tumors. Cancer journal (Sudbury, Mass.)\| PubMed ID: 26222088	2015
Senescence and cancer: An evolving inflammatory paradox. Biochimica et biophysica acta\| PubMed ID: 26453912	2016
Immune response to cancer therapy: mounting an effective antitumor response and mechanisms of resistance. Trends in cancer\| PubMed ID: 26457331	2015
Lymphatic Vessels, Inflammation, and Immunity in Skin Cancer. Cancer discovery\| PubMed ID: 26552413	2016
Bruton Tyrosine Kinase-Dependent Immune Cell Cross-talk Drives Pancreas Cancer. Cancer discovery\| PubMed ID: 26715645	2016
The Basis of Oncoimmunology. Cell\| PubMed ID: 26967289	2016
Distinct clinical patterns and immune infiltrates are observed at time of progression on targeted therapy versus immune checkpoint blockade for melanoma. Oncoimmunology\| PubMed ID: 27141370	2016
Alk5 inhibition increases delivery of macromolecular and protein-bound contrast agents to tumors. JCI insight\| PubMed ID: 27182558	2016
AACR Cancer Progress Report 2016. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 27697776	2016
Trim32 Deficiency Enhances Th2 Immunity and Predisposes to Features of Atopic Dermatitis. The Journal of investigative dermatology\| PubMed ID: 27720760	2017
MicroRNA regulation of endothelial TREX1 reprograms the tumour microenvironment. Nature communications\| PubMed ID: 27886180	2016
Colorectal Cancer Liver Metastasis: Evolving Paradigms and Future Directions. Cellular and molecular gastroenterology and hepatology\| PubMed ID: 28275683	2017
Quantitative Multiplex Immunohistochemistry Reveals Myeloid-Inflamed Tumor-Immune Complexity Associated with Poor Prognosis. Cell reports\| PubMed ID: 28380359	2017
Immune Escape in Breast Cancer During In Situ to Invasive Carcinoma Transition. Cancer discovery\| PubMed ID: 28652380	2017