Terrence Town

Zilkha Neurogenetic Institute, University of Southern California (USC)

Affiliated withUniversity of Southern California (USC)

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 4	2016

Other Publications

Article	Year
CD40 is expressed and functional on neuronal cells. The EMBO journal\| PubMed ID: 11847112	2002
p35/Cdk5 pathway mediates soluble amyloid-beta peptide-induced tau phosphorylation in vitro. Journal of neuroscience research\| PubMed ID: 12125077	2002
CD40-CD40L interaction in Alzheimer's disease. Current opinion in pharmacology\| PubMed ID: 12127879	2002
Role of CD40 ligand in amyloidosis in transgenic Alzheimer's mice. Nature neuroscience\| PubMed ID: 12402041	2002
Reduced Th1 and enhanced Th2 immunity after immunization with Alzheimer's beta-amyloid(1-42). Journal of neuroimmunology\| PubMed ID: 12417433	2002
CD45 isoform alteration in CD4+ T cells as a potential diagnostic marker of Alzheimer's disease. Journal of neuroimmunology\| PubMed ID: 12417447	2002
Increased vulnerability to focal ischemic brain injury in human apolipoprotein E4 knock-in mice. Journal of neuropathology and experimental neurology\| PubMed ID: 12638732	2003
Neuronal expression of CD22: novel mechanism for inhibiting microglial proinflammatory cytokine production. Glia\| PubMed ID: 15095367	2004
CD45 isoform RB as a molecular target to oppose lipopolysaccharide-induced microglial activation in mice. Neuroscience letters\| PubMed ID: 15147773	2004
Augmented delayed infarct expansion and reactive astrocytosis after permanent focal ischemia in apolipoprotein E4 knock-in mice. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 15181372	2004
Behavioral effects of CD40-CD40L pathway disruption in aged PSAPP mice. Brain research\| PubMed ID: 15223380	2004
Toll-like receptor 3 mediates West Nile virus entry into the brain causing lethal encephalitis. Nature medicine\| PubMed ID: 15558055	2004
CD40 signaling regulates innate and adaptive activation of microglia in response to amyloid beta-peptide. European journal of immunology\| PubMed ID: 15688347	2005
Modulation of astrocytic activation by arundic acid (ONO-2506) mitigates detrimental effects of the apolipoprotein E4 isoform after permanent focal ischemia in apolipoprotein E knock-in mice... Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 15689951	2005
Interchromosomal associations between alternatively expressed loci. Nature\| PubMed ID: 15880101	2005
Physiological regulation of the beta-amyloid precursor protein signaling domain by c-Jun N-terminal kinase JNK3 during neuronal differentiation. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 15944381	2005
Green tea epigallocatechin-3-gallate (EGCG) modulates amyloid precursor protein cleavage and reduces cerebral amyloidosis in Alzheimer transgenic mice. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 16177050	2005
T-cells in Alzheimer's disease. Neuromolecular medicine\| PubMed ID: 16247185	2005
The microglial "activation" continuum: from innate to adaptive responses. Journal of neuroinflammation\| PubMed ID: 16259628	2005
Microglia recognize double-stranded RNA via TLR3. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 16517751	2006
ADAM10 activation is required for green tea (-)-epigallocatechin-3-gallate-induced alpha-secretase cleavage of amyloid precursor protein. The Journal of biological chemistry\| PubMed ID: 16624814	2006
Arundic Acid ameliorates cerebral amyloidosis and gliosis in Alzheimer transgenic mice. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 16709678	2006
HSP70 enhances macrophage phagocytosis by interaction with lipid raft-associated TLR-7 and upregulating p38 MAPK and PI3K pathways. The Journal of surgical research\| PubMed ID: 16979664	2006
Antiviral peptides targeting the west nile virus envelope protein. Journal of virology\| PubMed ID: 17151121	2007
Transcutaneous beta-amyloid immunization reduces cerebral beta-amyloid deposits without T cell infiltration and microhemorrhage. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17264212	2007
NSAIDs for the chemoprevention of Alzheimer's disease. Sub-cellular biochemistry\| PubMed ID: 17612054	2007
Apoptotic hepatocyte DNA inhibits hepatic stellate cell chemotaxis via toll-like receptor 9. Hepatology (Baltimore, Md.)\| PubMed ID: 17705260	2007
Abrogation of macrophage migration inhibitory factor decreases West Nile virus lethality by limiting viral neuroinvasion. The Journal of clinical investigation\| PubMed ID: 17909632	2007
Control of toll-like receptor 7 expression is essential to restrict autoimmunity and dendritic cell proliferation. Immunity\| PubMed ID: 17997333	2007
Toll-like receptor modulation of murine cerebral malaria is dependent on the genetic background of the host. The Journal of infectious diseases\| PubMed ID: 18008236	2007
West Nile virus envelope protein inhibits dsRNA-induced innate immune responses. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 18056386	2007
Icam-1 participates in the entry of west nile virus into the central nervous system. Journal of virology\| PubMed ID: 18256150	2008
The stumpy gene is required for mammalian ciliogenesis. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18287022	2008
Peripherally administered human umbilical cord blood cells reduce parenchymal and vascular beta-amyloid deposits in Alzheimer mice. Stem cells and development\| PubMed ID: 18366296	2008
Defective p53 engagement after the induction of DNA damage in cells deficient in topoisomerase 3beta. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18367668	2008
Flavonoid-mediated presenilin-1 phosphorylation reduces Alzheimer's disease beta-amyloid production. Journal of cellular and molecular medicine\| PubMed ID: 18410522	2009
Overexpression of human S100B exacerbates brain damage and periinfarct gliosis after permanent focal ischemia. Stroke\| PubMed ID: 18451356	2008
Blocking TGF-beta-Smad2/3 innate immune signaling mitigates Alzheimer-like pathology. Nature medicine\| PubMed ID: 18516051	2008
Drak2 contributes to West Nile virus entry into the brain and lethal encephalitis. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 18641347	2008
TGF-beta signaling in dendritic cells is a prerequisite for the control of autoimmune encephalomyelitis. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18669656	2008
Primary cilia regulate hippocampal neurogenesis by mediating sonic hedgehog signaling. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18728187	2008
Inflammaging as a prodrome to Alzheimer's disease. Journal of neuroinflammation\| PubMed ID: 19014446	2008
Toll-like receptor 7 mitigates lethal West Nile encephalitis via interleukin 23-dependent immune cell infiltration and homing. Immunity\| PubMed ID: 19200759	2009
Approaches to determine expression of inflammatory cytokines. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 19347295	2009
Alternative Abeta immunotherapy approaches for Alzheimer's disease. CNS & neurological disorders drug targets\| PubMed ID: 19355932	2009
A role for the JAK-STAT1 pathway in blocking replication of HSV-1 in dendritic cells and macrophages. Virology journal\| PubMed ID: 19439086	2009
A protective function for interleukin 17A in T cell-mediated intestinal inflammation. Nature immunology\| PubMed ID: 19448631	2009
CNS infiltration of peripheral immune cells: D-Day for neurodegenerative disease? Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology\| PubMed ID: 19669892	2009
Overexpression of human S100B exacerbates cerebral amyloidosis and gliosis in the Tg2576 mouse model of Alzheimer's disease. Glia\| PubMed ID: 19705461	2010
IL-10 signaling blockade controls murine West Nile virus infection. PLoS pathogens\| PubMed ID: 19816558	2009
Mutant presenilin-1 deregulated peripheral immunity exacerbates Alzheimer-like pathology. Journal of cellular and molecular medicine\| PubMed ID: 19900216	2011
Can peripheral leukocytes be used as Alzheimer's disease biomarkers? Expert review of neurotherapeutics\| PubMed ID: 19903022	2009
Inflammation, immunity, and Alzheimer's disease. CNS & neurological disorders drug targets\| PubMed ID: 20205648	2010
Alzheimer's Disease Beyond Abeta. Expert review of neurotherapeutics\| PubMed ID: 20429127	2010
Macrophages in Alzheimer's disease: the blood-borne identity. Journal of neural transmission (Vienna, Austria : 1996)\| PubMed ID: 20517700	2010
Targeting S100B in Cerebral Ischemia and in Alzheimer's Disease. Cardiovascular psychiatry and neurology\| PubMed ID: 20862385	2010
Macrophage IL-12p70 signaling prevents HSV-1-induced CNS autoimmunity triggered by autoaggressive CD4+ Tregs. Investigative ophthalmology & visual science\| PubMed ID: 21220560	2011
CD45 deficiency drives amyloid-β peptide oligomers and neuronal loss in Alzheimer's disease mice. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 21273420	2011
The role of LAT in increased CD8+ T cell exhaustion in trigeminal ganglia of mice latently infected with herpes simplex virus 1. Journal of virology\| PubMed ID: 21307196	2011
Control of TH17 cells occurs in the small intestine. Nature\| PubMed ID: 21765430	2011
Adaptive and innate transforming growth factor beta signaling impact herpes simplex virus 1 latency and reactivation. Journal of virology\| PubMed ID: 21880769	2011
Myeloid differentiation factor-2 interacts with Lyn kinase and is tyrosine phosphorylated following lipopolysaccharide-induced activation of the TLR4 signaling pathway. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 21918188	2011
Tannic acid is a natural β-secretase inhibitor that prevents cognitive impairment and mitigates Alzheimer-like pathology in transgenic mice. The Journal of biological chemistry\| PubMed ID: 22219198	2012
Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis. Immunity\| PubMed ID: 22342844	2012
Basic biology and mechanisms of neural ciliogenesis and the B9 family. Molecular neurobiology\| PubMed ID: 22644387	2012
Rapid genetic targeting of pial surface neural progenitors and immature neurons by neonatal electroporation. Neural development\| PubMed ID: 22776033	2012
Microglia in Alzheimer's Disease: It's All About Context. International journal of Alzheimer's disease\| PubMed ID: 22779026	2012
IL-22 signaling contributes to West Nile encephalitis pathogenesis. PloS one\| PubMed ID: 22952908	2012
Ferulic acid is a nutraceutical β-secretase modulator that improves behavioral impairment and alzheimer-like pathology in transgenic mice. PloS one\| PubMed ID: 23409038	2013
Increasing hematopoietic stem cell yield to develop mice with human immune systems. BioMed research international\| PubMed ID: 23509770	2013
Innate immunity in Alzheimer's disease: a complex affair. CNS & neurological disorders drug targets\| PubMed ID: 23574177	2013
A transgenic Alzheimer rat with plaques, tau pathology, behavioral impairment, oligomeric aβ, and frank neuronal loss. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 23575824	2013
Brain injury, neuroinflammation and Alzheimer's disease. Frontiers in aging neuroscience\| PubMed ID: 23874297	2013
CD8α dendritic cells drive establishment of HSV-1 latency. PloS one\| PubMed ID: 24695322	2014
T-cell TGF-β signaling abrogation restricts medulloblastoma progression. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 25082897	2014
Methylene blue modulates β-secretase, reverses cerebral amyloidosis, and improves cognition in transgenic mice. The Journal of biological chemistry\| PubMed ID: 25157105	2014
MyD88 is dispensable for cerebral amyloidosis and neuroinflammation in APP/PS1 transgenic mice. The American journal of pathology\| PubMed ID: 25174876	2014
The role of the immune system in neurodegenerative disorders: Adaptive or maladaptive? Brain research\| PubMed ID: 25218556	2015
Il10 deficiency rebalances innate immunity to mitigate Alzheimer-like pathology. Neuron\| PubMed ID: 25619654	2015
Spatial proximity of homologous alleles and long noncoding RNAs regulate a switch in allelic gene expression. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 25770217	2015
Neuroinflammation in Alzheimer's disease. The Lancet. Neurology\| PubMed ID: 25792098	2015
Characterization of cancer stem cells and primary cilia in medulloblastoma. CNS & neurological disorders drug targets\| PubMed ID: 25921740	2015
Innate Immunity Fights Alzheimer's Disease. Trends in neurosciences\| PubMed ID: 26549882	2015
Increased Susceptibility of Humanized NSG Mice to Panton-Valentine Leukocidin and Staphylococcus aureus Skin Infection. PLoS pathogens\| PubMed ID: 26618545	2015
Multi-Shell Hybrid Diffusion Imaging (HYDI) at 7 Tesla in TgF344-AD Transgenic Alzheimer Rats. PloS one\| PubMed ID: 26683657	2015
CD8+ T Cells Play a Bystander Role in Mice Latently Infected with Herpes Simplex Virus 1. Journal of virology\| PubMed ID: 26962220	2016
Targeting innate immunity for neurodegenerative disorders of the central nervous system. Journal of neurochemistry\| PubMed ID: 27248001	2016
Interrelationship of Primary Virus Replication, Level of Latency, and Time to Reactivation in the Trigeminal Ganglia of Latently Infected Mice. Journal of virology\| PubMed ID: 27512072	2016
Amyloid Cascade into Clarity. Immunity\| PubMed ID: 27760336	2016
Interleukin-17A Promotes CD8+ T Cell Cytotoxicity To Facilitate West Nile Virus Clearance. Journal of virology\| PubMed ID: 27795421	2017
TLR8 Couples SOCS-1 and Restrains TLR7-Mediated Antiviral Immunity, Exacerbating West Nile Virus Infection in Mice. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 27798161	2016