Michelle Bradley

Department of Chemistry and Biochemistry, University of California, Los Angeles

Affiliated withUniversity of California, Los Angeles

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 11	2016

Other Publications

Article	Year
C/EBPbeta regulation in lipopolysaccharide-stimulated macrophages. Molecular and cellular biology\| PubMed ID: 12832471	2003
LXR-dependent gene expression is important for macrophage survival and the innate immune response. Cell\| PubMed ID: 15479645	2004
Lesion macrophages are a key target for the antiatherogenic effects of LXR agonists. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 15626767	2005
A role for the apoptosis inhibitory factor AIM/Spalpha/Api6 in atherosclerosis development. Cell metabolism\| PubMed ID: 16054063	2005
Development and validation of a rotor-gene real-time PCR assay for detection, identification, and quantification of Chlamydia trachomatis in a single reaction. Journal of clinical microbiology\| PubMed ID: 16390971	2006
Expression profiling of metalloproteinases and tissue inhibitors of metalloproteinases in normal and degenerate human achilles tendon. Arthritis and rheumatism\| PubMed ID: 16508964	2006
Phosphorylation of the liver X receptors. FEBS letters\| PubMed ID: 16904112	2006
The arginase II gene is an anti-inflammatory target of liver X receptor in macrophages. The Journal of biological chemistry\| PubMed ID: 16943198	2006
MRI of the ankle: effect on diagnostic confidence and patient management. AJR. American journal of roentgenology\| PubMed ID: 17056924	2006
Human Ikaros function in activated T cells is regulated by coordinated expression of its largest isoforms. The Journal of biological chemistry\| PubMed ID: 17135265	2007
Ligand activation of LXR beta reverses atherosclerosis and cellular cholesterol overload in mice lacking LXR alpha and apoE. The Journal of clinical investigation\| PubMed ID: 17657314	2007
N-Acylthiadiazolines, a new class of liver X receptor agonists with selectivity for LXRbeta. Journal of medicinal chemistry\| PubMed ID: 17665897	2007
LXR signaling couples sterol metabolism to proliferation in the acquired immune response. Cell\| PubMed ID: 18614014	2008
Preserved glucose tolerance in high-fat-fed C57BL/6 mice transplanted with PPARgamma-/-, PPARdelta-/-, PPARgammadelta-/-, or LXRalphabeta-/- bone marrow. Journal of lipid research\| PubMed ID: 18772483	2009
TLR/MyD88 and liver X receptor alpha signaling pathways reciprocally control Chlamydia pneumoniae-induced acceleration of atherosclerosis. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 18981139	2008
T0901317, an LXR agonist, augments PKA-induced vascular cell calcification. FEBS letters\| PubMed ID: 19327357	2009
Apoptotic cells promote their own clearance and immune tolerance through activation of the nuclear receptor LXR. Immunity\| PubMed ID: 19646905	2009
The identification of indacaterol as an ultralong-acting inhaled beta2-adrenoceptor agonist. Journal of medicinal chemistry\| PubMed ID: 20402514	2010
A physical properties based approach for the exploration of a 4-hydroxybenzothiazolone series of beta2-adrenoceptor agonists as inhaled long-acting bronchodilators. Bioorganic & medicinal chemistry letters\| PubMed ID: 20655218	2010
LXR promotes the maximal egress of monocyte-derived cells from mouse aortic plaques during atherosclerosis regression. The Journal of clinical investigation\| PubMed ID: 21041949	2010
Constitutive activation of LXR in macrophages regulates metabolic and inflammatory gene expression: identification of ARL7 as a direct target. Journal of lipid research\| PubMed ID: 21187453	2011
Design and synthesis of a library of chemokine antagonists. Bioorganic & medicinal chemistry letters\| PubMed ID: 21940167	2011
The in vitro metabolism of sphingosine-1-phosphate: identification; inhibition and pharmacological implications. European journal of pharmacology\| PubMed ID: 21970805	2011
Mortality in carotid sinus hypersensitivity: a cohort study. BMJ open\| PubMed ID: 22021728	2011
Five years of denosumab exposure in women with postmenopausal osteoporosis: results from the first two years of the FREEDOM extension. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research\| PubMed ID: 22113951	2012
Monoamine oxidase A expression is suppressed in human cholangiocarcinoma via coordinated epigenetic and IL-6-driven events. Laboratory investigation; a journal of technical methods and pathology\| PubMed ID: 22906985	2012
An investigation into the structure-activity relationships associated with the systematic modification of the β(2)-adrenoceptor agonist indacaterol. Bioorganic & medicinal chemistry letters\| PubMed ID: 22932315	2012
The effect of three or six years of denosumab exposure in women with postmenopausal osteoporosis: results from the FREEDOM extension. The Journal of clinical endocrinology and metabolism\| PubMed ID: 23979955	2013
The discovery of potent, orally bioavailable pyrazolo and triazolopyrimidine CXCR2 receptor antagonists. Bioorganic & medicinal chemistry letters\| PubMed ID: 24332493	2014
Investigating the molecular mechanisms through which FTY720-P causes persistent S1P1 receptor internalization. British journal of pharmacology\| PubMed ID: 24641481	2014
The discovery of potent, orally bioavailable pyrimidine-5-carbonitrile-6-alkyl CXCR2 receptor antagonists. Bioorganic & medicinal chemistry letters\| PubMed ID: 24974342	2014
The identification of 7-[(R)-2-((1S,2S)-2-benzyloxycyclopentylamino)-1-hydroxyethyl]-4-hydroxybenzothiazolone as an inhaled long-acting β2-adrenoceptor agonist. Bioorganic & medicinal chemistry letters\| PubMed ID: 25065493	2014
Functional desensitization of the β 2 adrenoceptor is not dependent on agonist efficacy. Pharmacology research & perspectives\| PubMed ID: 25692019	2015
Interim estimates of male human papillomavirus vaccination coverage in the school-based program in Australia. Communicable diseases intelligence quarterly report\| PubMed ID: 26234254	2015
Long Receptor Residence Time of C26 Contributes to Super Agonist Activity at the Human β2 Adrenoceptor. Molecular pharmacology\| PubMed ID: 26772612	2016
Fevipiprant (QAW039), a Slowly Dissociating CRTh2 Antagonist with the Potential for Improved Clinical Efficacy. Molecular pharmacology\| PubMed ID: 26916831	2016
The Treatment of Chronic Coccydynia and Postcoccygectomy Pain With Pelvic Floor Physical Therapy. PM & R : the journal of injury, function, and rehabilitation\| PubMed ID: 27565640	2016