Alma Zernecke

Institute of Experimental Biomedicine, Würzburg University

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 6	2017

Other Publications

Article	Year
JAM-1 is a ligand of the beta(2) integrin LFA-1 involved in transendothelial migration of leukocytes. Nature immunology\| PubMed ID: 11812992	2002
Suppression of endothelial adhesion molecule up-regulation with cyclopentenone prostaglandins is dissociated from IkappaB-alpha kinase inhibition and cell death induction. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 12692090	2003
Residual mesorectal lymph node involvement following neoadjuvant combined-modality therapy: rationale for radical resection? Annals of surgical oncology\| PubMed ID: 14761922	2004
Cyclopentenone prostaglandins induce endothelial cell apoptosis independent of the peroxisome proliferator-activated receptor-gamma. European journal of immunology\| PubMed ID: 14971050	2004
Chemokines: key regulators of mononuclear cell recruitment in atherosclerotic vascular disease. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 15319268	2004
Targeted disruption of cd73/ecto-5'-nucleotidase alters thromboregulation and augments vascular inflammatory response. Circulation research\| PubMed ID: 15358667	2004
Crucial role of the CCL2/CCR2 axis in neointimal hyperplasia after arterial injury in hyperlipidemic mice involves early monocyte recruitment and CCL2 presentation on platelets. Circulation research\| PubMed ID: 15528472	2004
Inflammatory mediators in atherosclerotic vascular disease. Basic research in cardiology\| PubMed ID: 15645164	2005
Involvement of JAM-A in mononuclear cell recruitment on inflamed or atherosclerotic endothelium: inhibition by soluble JAM-A. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 15681301	2005
Transplantation of human umbilical vein endothelial cells improves left ventricular function in a rat model of myocardial infarction. Basic research in cardiology\| PubMed ID: 15690102	2005
SDF-1alpha/CXCR4 axis is instrumental in neointimal hyperplasia and recruitment of smooth muscle progenitor cells. Circulation research\| PubMed ID: 15761195	2005
Platelet microparticles: a transcellular delivery system for RANTES promoting monocyte recruitment on endothelium. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 15890969	2005
Reduction of the aortic inflammatory response in spontaneous atherosclerosis by blockade of macrophage migration inhibitory factor (MIF). Atherosclerosis\| PubMed ID: 15921687	2006
Importance of junctional adhesion molecule-A for neointimal lesion formation and infiltration in atherosclerosis-prone mice. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 16306427	2006
Deficiency in CCR5 but not CCR1 protects against neointima formation in atherosclerosis-prone mice: involvement of IL-10. Blood\| PubMed ID: 16467202	2006
Thienopyridines in percutaneous coronary interventions: standard procedures and high risk subsets. Current pharmaceutical design\| PubMed ID: 16611112	2006
CD73/ecto-5'-nucleotidase protects against vascular inflammation and neointima formation. Circulation\| PubMed ID: 16636171	2006
MCP-1 induces a novel transcription factor with proapoptotic activity. Circulation research\| PubMed ID: 16690887	2006
SDF-1alpha-mediated tissue repair by stem cells: a promising tool in cardiovascular medicine? Trends in cardiovascular medicine\| PubMed ID: 16713531	2006
Vascular endothelial growth factor-A induces plaque expansion in ApoE knock-out mice by promoting de novo leukocyte recruitment. Blood\| PubMed ID: 16990600	2007
Ccr5 but not Ccr1 deficiency reduces development of diet-induced atherosclerosis in mice. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 17138939	2007
Chemokines: inflammatory mediators of atherosclerosis. Archives of physiology and biochemistry\| PubMed ID: 17178596	2006
Importance of CXC chemokine receptor 2 in the homing of human peripheral blood endothelial progenitor cells to sites of arterial injury. Circulation research\| PubMed ID: 17272812	2007
MIF is a noncognate ligand of CXC chemokine receptors in inflammatory and atherogenic cell recruitment. Nature medicine\| PubMed ID: 17435771	2007
Perivascular mast cells promote atherogenesis and induce plaque destabilization in apolipoprotein E-deficient mice. Circulation\| PubMed ID: 17470698	2007
Chemokines in vascular remodeling. Thrombosis and haemostasis\| PubMed ID: 17479183	2007
Regulation of endothelial progenitor cell homing after arterial injury. Thrombosis and haemostasis\| PubMed ID: 17721606	2007
Y-box binding protein-1 controls CC chemokine ligand-5 (CCL5) expression in smooth muscle cells and contributes to neointima formation in atherosclerosis-prone mice. Circulation\| PubMed ID: 17893273	2007
Expression of HIF-1alpha in injured arteries controls SDF-1alpha mediated neointima formation in apolipoprotein E deficient mice. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 17932320	2007
Protective role of CXC receptor 4/CXC ligand 12 unveils the importance of neutrophils in atherosclerosis. Circulation research\| PubMed ID: 17991882	2008
C1-esterase inhibitor protects against neointima formation after arterial injury in atherosclerosis-prone mice. Circulation\| PubMed ID: 18071075	2008
The CD40-TRAF6 axis is the key regulator of the CD40/CD40L system in neointima formation and arterial remodeling. Blood\| PubMed ID: 18195092	2008
Macrophage migration inhibitory factor in cardiovascular disease. Circulation\| PubMed ID: 18362243	2008
Role of smooth muscle cGMP/cGKI signaling in murine vascular restenosis. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 18420996	2008
Neutrophil secretion products pave the way for inflammatory monocytes. Blood\| PubMed ID: 18490516	2008
Sialyltransferase ST3Gal-IV controls CXCR2-mediated firm leukocyte arrest during inflammation. The Journal of experimental medicine\| PubMed ID: 18519646	2008
Chemokines in atherosclerosis: an update. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 18566299	2008
Adult progenitor cells in vascular remodeling during atherosclerosis. Biological chemistry\| PubMed ID: 18627306	2008
Blockade of angio-associated migratory cell protein inhibits smooth muscle cell migration and neointima formation in accelerated atherosclerosis. Journal of the American College of Cardiology\| PubMed ID: 18634987	2008
Caffeine enhances endothelial repair by an AMPK-dependent mechanism. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 18757291	2008
Dynamic changes in murine vessel geometry assessed by high-resolution magnetic resonance angiography: a 9.4T study. Journal of magnetic resonance imaging : JMRI\| PubMed ID: 18777558	2008
The multifaceted contributions of leukocyte subsets to atherosclerosis: lessons from mouse models. Nature reviews. Immunology\| PubMed ID: 18825131	2008
Structural determinants of MIF functions in CXCR2-mediated inflammatory and atherogenic leukocyte recruitment. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18852457	2008
CX3CR1 is required for monocyte homeostasis and atherogenesis by promoting cell survival. Blood\| PubMed ID: 18971423	2009
Disrupting functional interactions between platelet chemokines inhibits atherosclerosis in hyperlipidemic mice. Nature medicine\| PubMed ID: 19122657	2009
Regulated release and functional modulation of junctional adhesion molecule A by disintegrin metalloproteinases. Blood\| PubMed ID: 19258599	2009
Importance of junctional adhesion molecule-C for neointimal hyperplasia and monocyte recruitment in atherosclerosis-prone mice-brief report. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 19520977	2009
Neutrophils launch monocyte extravasation by release of granule proteins. Thrombosis and haemostasis\| PubMed ID: 19652869	2009
Alteration of matrix metalloproteinases in selective left ventricular adriamycin-induced cardiomyopathy in the pig. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation\| PubMed ID: 19782292	2009
Evaluation of a novel system for hypothermic oxygenated pulsatile perfusion preservation. The International journal of artificial organs\| PubMed ID: 19943234	2009
Delivery of microRNA-126 by apoptotic bodies induces CXCL12-dependent vascular protection. Science signaling\| PubMed ID: 19996457	2009
Chemokines in the vascular inflammatory response of atherosclerosis. Cardiovascular research\| PubMed ID: 20007309	2010
Soluble CD40 ligand impairs the function of peripheral blood angiogenic outgrowth cells and increases neointimal formation after arterial injury. Circulation\| PubMed ID: 20048211	2010
Deficient CD40-TRAF6 signaling in leukocytes prevents atherosclerosis by skewing the immune response toward an antiinflammatory profile. The Journal of experimental medicine\| PubMed ID: 20100871	2010
Functional contribution of elevated circulating and hepatic non-classical CD14CD16 monocytes to inflammation and human liver fibrosis. PloS one\| PubMed ID: 20548789	2010
Myeloid type I interferon signaling promotes atherosclerosis by stimulating macrophage recruitment to lesions. Cell metabolism\| PubMed ID: 20674859	2010
Platelet CD40L mediates thrombotic and inflammatory processes in atherosclerosis. Blood\| PubMed ID: 20705757	2010
C5a receptor targeting in neointima formation after arterial injury in atherosclerosis-prone mice. Circulation\| PubMed ID: 20733098	2010
A new monocyte chemotactic protein-1/chemokine CC motif ligand-2 competitor limiting neointima formation and myocardial ischemia/reperfusion injury in mice. Journal of the American College of Cardiology\| PubMed ID: 21087715	2010
Role of the CX3C chemokine receptor CX3CR1 in the pathogenesis of atherosclerosis after aortic transplantation. PloS one\| PubMed ID: 28234900	2017
MIF-chemokine receptor interactions in atherogenesis are dependent on an N-loop-based 2-site binding mechanism. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 21106938	2011
Non- invasive in vivo analysis of a murine aortic graft using high resolution ultrasound microimaging. European journal of radiology\| PubMed ID: 21334152	2012
Complement C5a inhibition reduces atherosclerosis in ApoE-/- mice. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 21490292	2011
The soluble CTLA-4 splice variant protects from type 1 diabetes and potentiates regulatory T-cell function. Diabetes\| PubMed ID: 21602513	2011
CCL17-expressing dendritic cells drive atherosclerosis by restraining regulatory T cell homeostasis in mice. The Journal of clinical investigation\| PubMed ID: 21633167	2011
Neutrophil-derived cathelicidin protects from neointimal hyperplasia. Science translational medicine\| PubMed ID: 21974936	2011
Double-edged role of the CXCL12/CXCR4 axis in experimental myocardial infarction. Journal of the American College of Cardiology\| PubMed ID: 22115649	2011
microRNAs in the regulation of dendritic cell functions in inflammation and atherosclerosis. Journal of molecular medicine (Berlin, Germany)\| PubMed ID: 22307520	2012
Auto-antigenic protein-DNA complexes stimulate plasmacytoid dendritic cells to promote atherosclerosis. Circulation\| PubMed ID: 22388324	2012
Hematopoietic interferon regulatory factor 8-deficiency accelerates atherosclerosis in mice. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 22556330	2012
Plasmacytoid dendritic cells in atherosclerosis. Frontiers in physiology\| PubMed ID: 22754539	2012
Visualization of vascular inflammation in the atherosclerotic mouse by ultrasmall superparamagnetic iron oxide vascular cell adhesion molecule-1-specific nanoparticles. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 22879583	2012
Pathophysiological mechanisms of carotid plaque vulnerability: impact on ischemic stroke. Archivum immunologiae et therapiae experimentalis\| PubMed ID: 22945688	2012
Improving the treatment of atherosclerosis by linking anti-inflammatory and lipid modulating strategies. Heart (British Cardiac Society)\| PubMed ID: 23086996	2012
Regulatory T cells are strong promoters of acute ischemic stroke in mice by inducing dysfunction of the cerebral microvasculature. Blood\| PubMed ID: 23160472	2013
Distinct functions of chemokine receptor axes in the atherogenic mobilization and recruitment of classical monocytes. EMBO molecular medicine\| PubMed ID: 23417922	2013
Early venous manifestation of Ehlers-Danlos syndrome Type IV through a novel mutation in COL3A1. Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology\| PubMed ID: 23688910	2013
Endothelial junctional adhesion molecule-a guides monocytes into flow-dependent predilection sites of atherosclerosis. Circulation\| PubMed ID: 24065611	2014
CCR6 selectively promotes monocyte mediated inflammation and atherogenesis in mice. Thrombosis and haemostasis\| PubMed ID: 24114205	2013
Role of extracellular RNA in atherosclerotic plaque formation in mice. Circulation\| PubMed ID: 24201302	2014
Molecular imaging of inflammation in atherosclerosis. Theranostics\| PubMed ID: 24312156	2013
Chemokines in atherosclerosis: proceedings resumed. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 24436368	2014
Bone marrow-specific knock-in of a non-activatable Ikkα kinase mutant influences haematopoiesis but not atherosclerosis in Apoe-deficient mice. PloS one\| PubMed ID: 24498325	2014
Controlled intramyocardial release of engineered chemokines by biodegradable hydrogels as a treatment approach of myocardial infarction. Journal of cellular and molecular medicine\| PubMed ID: 24512349	2014
Dendritic cell subset distributions in the aorta in healthy and atherosclerotic mice. PloS one\| PubMed ID: 24551105	2014
Programmed Cell Death-1 Deficiency Exacerbates T Cell Activation and Atherogenesis despite Expansion of Regulatory T Cells in Atherosclerosis-Prone Mice. PloS one\| PubMed ID: 24691202	2014
CXCR4 blockade induces atherosclerosis by affecting neutrophil function. Journal of molecular and cellular cardiology\| PubMed ID: 24816217	2014
Distinct functions of specialized dendritic cell subsets in atherosclerosis and the road ahead. Scientifica\| PubMed ID: 24818041	2014
Quantitative expression and localization of cysteine and aspartic proteases in human abdominal aortic aneurysms. Experimental & molecular medicine\| PubMed ID: 24833013	2014
Noncoding RNAs in vascular inflammation and atherosclerosis: recent advances toward therapeutic applications. Current opinion in lipidology\| PubMed ID: 25051497	2014
Establishment of a new murine elastase-induced aneurysm model combined with transplantation. PloS one\| PubMed ID: 25068788	2014
Response to letter regarding article "Role of extracellular RNA in atherosclerotic plaque formation in mice". Circulation\| PubMed ID: 25311624	2014
STAT1-dependent signal integration between IFNγ and TLR4 in vascular cells reflect pro-atherogenic responses in human atherosclerosis. PloS one\| PubMed ID: 25478796	2014
The hemostatic system as a regulator of inflammation in atherosclerosis. IUBMB life\| PubMed ID: 25491152	2014
Echogenic perfluorohexane-loaded macrophages adhere in vivo to activated vascular endothelium in mice, an explorative study. Cardiovascular ultrasound\| PubMed ID: 25567641	2015
Dendritic cells in atherosclerosis: evidence in mice and humans. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 25675999	2015
Macrophages and immune cells in atherosclerosis: recent advances and novel concepts. Basic research in cardiology\| PubMed ID: 25947006	2015
CD8+ T Cells Regulate Monopoiesis and Circulating Ly6C-high Monocyte Levels in Atherosclerosis in Mice. Circulation research\| PubMed ID: 25991812	2015
Stimulating arteriogenesis but not atherosclerosis: IFN-α/β receptor subunit 1 as a novel therapeutic target. Cardiovascular research\| PubMed ID: 26084309	2015
Deficiency of HIF1α in Antigen-Presenting Cells Aggravates Atherosclerosis and Type 1 T-Helper Cell Responses in Mice. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 26404487	2015
Carotid Plaque Morphology Is Significantly Associated With Sex, Age, and History of Neurological Symptoms. Stroke\| PubMed ID: 26451032	2015
Efficacy and Safety of Platelet Glycoprotein Receptor Blockade in Aged and Comorbid Mice With Acute Experimental Stroke. Stroke; a journal of cerebral circulation\| PubMed ID: 26486866	2015
Histone acetylation and methylation significantly change with severity of atherosclerosis in human carotid plaques. Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology\| PubMed ID: 26764138	2016
Histone acetylation and histone acetyltransferases show significant alterations in human abdominal aortic aneurysm. Clinical epigenetics\| PubMed ID: 26767057	2016
Aneurysm miRNA Signature Differs, Depending on Disease Localization and Morphology. International journal of molecular sciences\| PubMed ID: 26771601	2016
Extracellular Ribonucleic Acids (RNA) Enter the Stage in Cardiovascular Disease. Circulation research\| PubMed ID: 26846641	2016
Targeting In-Stent-Stenosis with RGD- and CXCL1-Coated Mini-Stents in Mice. PloS one\| PubMed ID: 27192172	2016
Regulation of matrix metalloproteinases (MMPs) expression and secretion in MDA-MB-231 breast cancer cells by LIM and SH3 protein 1 (LASP1). Oncotarget\| PubMed ID: 27588391	2016
Increased intermediate CD14(++)CD16(++) monocyte subset levels associate with restenosis after peripheral percutaneous transluminal angioplasty. Atherosclerosis\| PubMed ID: 27615596	2016
Protective and pathogenic roles of CD8(+) T cells in atherosclerosis. Basic research in cardiology\| PubMed ID: 27783202	2016
Coagulation factor XII induces pro-inflammatory cytokine responses in macrophages and promotes atherosclerosis in mice. Thrombosis and haemostasis\| PubMed ID: 27786338	2017
Congenital valvular defects associated with deleterious mutations in the PLD1 gene. Journal of medical genetics\| PubMed ID: 27799408	2017
CD98 promotes vascular smooth muscle cell accumulation in atherosclerosis to confer plaque stability. Atherosclerosis\| PubMed ID: 27939649	2017
The "Intermediate" CD14(++)CD16(+) monocyte subset increases in severe peripheral artery disease in humans. Scientific reports\| PubMed ID: 27991581	2016
Targeting Elastase for Molecular Imaging of Early Atherosclerotic Lesions. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 28062502	2017
Macrophages in vascular inflammation and atherosclerosis. Pflugers Archiv : European journal of physiology\| PubMed ID: 28168325	2017
Visualization of endothelial barrier damage prior to formation of atherosclerotic plaques. Histochemistry and cell biology\| PubMed ID: 28343238	2017
Deletion of Batf3-dependent antigen-presenting cells does not affect atherosclerotic lesion formation in mice. PloS one\| PubMed ID: 28771609	2017
Hypercholesterolemia induced cerebral small vessel disease. PloS one\| PubMed ID: 28796818	2017
Antigen-presenting dendritic cells in atherosclerosis. European journal of pharmacology\| PubMed ID: 28822856	2017
Cell differentiation defines acute and chronic infection cell types in Staphylococcus aureus. eLife\| PubMed ID: 28893374	2017
Extracellular Cyclophilin A Augments Platelet-Dependent Thrombosis and Thromboinflammation. Thrombosis and haemostasis\| PubMed ID: 28981554	2017