Ki-Hyuk Shin

The Shapiro Family Laboratory of Viral Oncology and Aging Research, The UCLA School of Dentistry

Affiliated withThe UCLA School of Dentistry UCLA Jonsson Comprehensive Cancer Center

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 15	2017

Other Publications

Article	Year
Mutational analysis of promoters of mismatch repair genes hMSH2 and hMLH1 in hereditary nonpolyposis colorectal cancer and early onset colorectal cancer patients: identification of three nov... Cancer research\| PubMed ID: 11782355	2002
Characterization of novel cell lines established from three human oral squamous cell carcinomas. International journal of oncology\| PubMed ID: 12011992	2002
Prevalence of microsatellite instability, inactivation of mismatch repair genes, p53 mutation, and human papillomavirus infection in Korean oral cancer patients. International journal of oncology\| PubMed ID: 12118324	2002
Inactivation of the PTEN gene by mutation, exonic deletion, and loss of transcript in human oral squamous cell carcinomas. International journal of oncology\| PubMed ID: 12370746	2002
Glutathione S-transferase M1 associated with cancer occurrence in Korean HNPCC families carrying the hMLH1/hMSH2 mutation. Oncology reports\| PubMed ID: 12579293	2003
Absence of hamTERT gene expression is associated with promoter hypermethylation in immortal hamster buccal pouch epithelial cells. International journal of oncology\| PubMed ID: 12739004	2003
Senescence-associated genes in normal human oral keratinocytes. Experimental cell research\| PubMed ID: 12837283	2003
Microsatellite instability and mutations in DNA mismatch repair genes in sporadic colorectal cancers. Diseases of the colon and rectum\| PubMed ID: 12907901	2003
Introduction of human telomerase reverse transcriptase to normal human fibroblasts enhances DNA repair capacity. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 15073136	2004
Senescence occurs with hTERT repression and limited telomere shortening in human oral keratinocytes cultured with feeder cells. Journal of cellular physiology\| PubMed ID: 15095283	2004
Normal human oral keratinocytes demonstrate abnormal DNA end joining activity during replicative senescence. Mechanisms of ageing and development\| PubMed ID: 15722106	2005
Senescence-associated decline in the intranuclear accumulation of hOGG1-alpha and impaired 8-oxo-dG repair activity in senescing normal human oral keratinocytes in vivo. Experimental cell research\| PubMed ID: 16122734	2005
HPV-16 E6 oncoprotein impairs the fidelity of DNA end-joining via p53-dependent and -independent pathways. International journal of oncology\| PubMed ID: 16327998	2006
Abnormal DNA end-joining activity in human head and neck cancer. International journal of molecular medicine\| PubMed ID: 16596281	2006
Heterogeneous nuclear ribonucleoprotein G shows tumor suppressive effect against oral squamous cell carcinoma cells. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 16707624	2006
Bmi-1 cooperates with human papillomavirus type 16 E6 to immortalize normal human oral keratinocytes. Experimental cell research\| PubMed ID: 17161394	2007
p53 promotes the fidelity of DNA end-joining activity by, in part, enhancing the expression of heterogeneous nuclear ribonucleoprotein G. DNA repair\| PubMed ID: 17387044	2007
Heterogeneous nuclear ribonucleoprotein G, nitric oxide, and oral carcinogenesis. Nitric oxide : biology and chemistry\| PubMed ID: 18474262	2008
hnRNP G elicits tumor-suppressive activity in part by upregulating the expression of Txnip. Biochemical and biophysical research communications\| PubMed ID: 18541147	2008
HIV-1 Tat enhances replicative potential of human oral keratinocytes harboring HPV-16 genome. International journal of oncology\| PubMed ID: 18813791	2008
Association of hsp90 to the hTERT promoter is necessary for hTERT expression in human oral cancer cells. Carcinogenesis\| PubMed ID: 18820283	2008
Bmi-1 extends the life span of normal human oral keratinocytes by inhibiting the TGF-beta signaling. Experimental cell research\| PubMed ID: 20630502	2010
Grainyhead-like 2 enhances the human telomerase reverse transcriptase gene expression by inhibiting DNA methylation at the 5'-CpG island in normal human keratinocytes. The Journal of biological chemistry\| PubMed ID: 20938050	2010
miR-181a shows tumor suppressive effect against oral squamous cell carcinoma cells by downregulating K-ras. Biochemical and biophysical research communications\| PubMed ID: 21167132	2011
Radioprotective effects of Bmi-1 involve epigenetic silencing of oxidase genes and enhanced DNA repair in normal human keratinocytes. The Journal of investigative dermatology\| PubMed ID: 21307872	2011
Identification of senescence-inducing microRNAs in normal human keratinocytes. International journal of oncology\| PubMed ID: 21725593	2011
Expression and mutation analysis of heterogeneous nuclear ribonucleoprotein G in human oral cancer. Oral oncology\| PubMed ID: 21840245	2011
DeltaNp63α protein triggers epithelial-mesenchymal transition and confers stem cell properties in normal human keratinocytes. The Journal of biological chemistry\| PubMed ID: 21880709	2011
TNFα enhances cancer stem cell-like phenotype via Notch-Hes1 activation in oral squamous cell carcinoma cells. Biochemical and biophysical research communications\| PubMed ID: 22728043	2012
Camphorquinone inhibits odontogenic differentiation of dental pulp cells and triggers release of inflammatory cytokines. Journal of endodontics\| PubMed ID: 23228258	2013
Efavirenz induces autophagy and aberrant differentiation in normal human keratinocytes. International journal of molecular medicine\| PubMed ID: 23563240	2013
2-Hydroxyethyl methacrylate inhibits migration of dental pulp stem cells. Journal of endodontics\| PubMed ID: 23953290	2013
Development of oral osteomucosal tissue constructs in vitro and localization of fluorescently-labeled bisphosphonates to hard and soft tissue. International journal of molecular medicine\| PubMed ID: 24920042	2014
Impaired bone resorption and woven bone formation are associated with development of osteonecrosis of the jaw-like lesions by bisphosphonate and anti-receptor activator of NF-κB ligand antib... The American journal of pathology\| PubMed ID: 25173134	2014
Osteo-/odontogenic differentiation of induced mesenchymal stem cells generated through epithelial-mesenchyme transition of cultured human keratinocytes. Journal of endodontics\| PubMed ID: 25201509	2014
The p63 Gene Is Regulated by Grainyhead-like 2 (GRHL2) through Reciprocal Feedback and Determines the Epithelial Phenotype in Human Keratinocytes. The Journal of biological chemistry\| PubMed ID: 26085095	2015
Regulation of p53 during senescence in normal human keratinocytes. Aging cell\| PubMed ID: 26138448	2015
Elevated expression of JMJD6 is associated with oral carcinogenesis and maintains cancer stemness properties. Carcinogenesis\| PubMed ID: 26645717	2016
Human papillomavirus 16 (HPV16) enhances tumor growth and cancer stemness of HPV-negative oral/oropharyngeal squamous cell carcinoma cells via miR-181 regulation. Papillomavirus research (Amsterdam, Netherlands)\| PubMed ID: 26693182	2015
Grainyhead-like 2 regulates epithelial plasticity and stemness in oral cancer cells. Carcinogenesis\| PubMed ID: 26933170	2016
Orai1 mediates osteogenic differentiation via BMP signaling pathway in bone marrow mesenchymal stem cells. Biochemical and biophysical research communications\| PubMed ID: 27086849	2016
Orai1 promotes tumor progression by enhancing cancer stemness via NFAT signaling in oral/oropharyngeal squamous cell carcinoma. Oncotarget\| PubMed ID: 27259269	2016
IL-36 Induces Bisphosphonate-Related Osteonecrosis of the Jaw-Like Lesions in Mice by Inhibiting TGF-β-Mediated Collagen Expression. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research\| PubMed ID: 27567012	2016
Preexisting Periapical Inflammatory Condition Exacerbates Tooth Extraction-induced Bisphosphonate-related Osteonecrosis of the Jaw Lesions in Mice. Journal of endodontics\| PubMed ID: 27637460	2016
Zinc Up-Regulates Insulin Secretion from β Cell-Like Cells Derived from Stem Cells from Human Exfoliated Deciduous Tooth (SHED). International journal of molecular sciences\| PubMed ID: 27983594	2016