Roland Baur

Institute of Biochemistry and Molecular Medicine, University of Bern

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 5	2016

Other Publications

Article	Year
A GABA(A) receptor of defined subunit composition and positioning: concatenation of five subunits. FEBS letters\| PubMed ID: 16494876	2006
N-Substituted 4-amino-3,3-dipropyl-2(3H)-furanones: new positive allosteric modulators of the GABA(A) receptor sharing electrophysiological properties with the anticonvulsant loreclezole. Journal of medicinal chemistry\| PubMed ID: 12061884	2002
Functional characterization of the new human GABA(A) receptor mutation beta3(R192H). Human genetics\| PubMed ID: 12189488	2002
Forced subunit assembly in alpha1beta2gamma2 GABAA receptors. Insight into the absolute arrangement. The Journal of biological chemistry\| PubMed ID: 12324466	2002
Anxiolytic effect of wogonin, a benzodiazepine receptor ligand isolated from Scutellaria baicalensis Georgi. Biochemical pharmacology\| PubMed ID: 12392823	2002
On high- and low-affinity agonist sites in GABAA receptors. Journal of neurochemistry\| PubMed ID: 14511110	2003
Naturally occurring 2'-hydroxyl-substituted flavonoids as high-affinity benzodiazepine site ligands. Biochemical pharmacology\| PubMed ID: 14637197	2003
Individual properties of the two functional agonist sites in GABA(A) receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 14657175	2003
The flavone hispidulin, a benzodiazepine receptor ligand with positive allosteric properties, traverses the blood-brain barrier and exhibits anticonvulsive effects. British journal of pharmacology\| PubMed ID: 15231642	2004
Benzodiazepines affect channel opening of GABA A receptors induced by either agonist binding site. Molecular pharmacology\| PubMed ID: 15657366	2005
Conformational changes at benzodiazepine binding sites of GABA(A) receptors detected with a novel technique. Journal of neurochemistry\| PubMed ID: 15686488	2005
Novel plant substances acting as beta subunit isoform-selective positive allosteric modulators of GABAA receptors. Molecular pharmacology\| PubMed ID: 15939801	2005
Homeopathic medical practice: long-term results of a cohort study with 3981 patients. BMC public health\| PubMed ID: 16266440	2005
Influence of the point mutation alpha-1-H101R on the assembly of gamma-aminobutyric acid type A receptors. Neuroreport\| PubMed ID: 16272886	2005
Consequence of the presence of two different beta subunit isoforms in a GABA(A) receptor. Journal of neurochemistry\| PubMed ID: 16300645	2005
Proximity-accelerated chemical coupling reaction in the benzodiazepine-binding site of gamma-aminobutyric acid type A receptors: superposition of different allosteric modulators. The Journal of biological chemistry\| PubMed ID: 17626010	2007
Two neighboring residues of loop A of the alpha1 subunit point towards the benzodiazepine binding site of GABAA receptors. FEBS letters\| PubMed ID: 17854801	2007
Replacement of histidine in position 105 in the α₅ subunit by cysteine stimulates zolpidem sensitivity of α₅β₂γ₂ GABA(A) receptors. Journal of neurochemistry\| PubMed ID: 17953656	2007
The promiscuous role of the epsilon subunit in GABAA receptor biogenesis. Molecular and cellular neurosciences\| PubMed ID: 18206389	2008
Novel chloride channel mutations leading to mild myotonia among Chinese. Neuromuscular disorders : NMD\| PubMed ID: 18579381	2008
Covalent modification of GABAA receptor isoforms by a diazepam analogue provides evidence for a novel benzodiazepine binding site that prevents modulation by these drugs. Journal of neurochemistry\| PubMed ID: 18643789	2008
Unanticipated structural and functional properties of delta-subunit-containing GABAA receptors. The Journal of biological chemistry\| PubMed ID: 19141615	2009
Homeopathic treatment of patients with chronic low back pain: A prospective observational study with 2 years' follow-up. The Clinical journal of pain\| PubMed ID: 19590483	2009
Structure of alpha6 beta3 delta GABA(A) receptors and their lack of ethanol sensitivity. Journal of neurochemistry\| PubMed ID: 19765192	2009
Relative positioning of diazepam in the benzodiazepine-binding-pocket of GABA receptors. Journal of neurochemistry\| PubMed ID: 19804380	2009
Use of concatamers to study GABAA receptor architecture and function: application to delta-subunit-containing receptors and possible pitfalls. Biochemical Society transactions\| PubMed ID: 19909272	2009
Highly potent modulation of GABA(A) receptors by valerenic acid derivatives. ChemMedChem\| PubMed ID: 20235267	2010
Diversity of structure and function of alpha1alpha6beta3delta GABAA receptors: comparison with alpha1beta3delta and alpha6beta3delta receptors. The Journal of biological chemistry\| PubMed ID: 20382738	2010
Monepantel allosterically activates DEG-3/DES-2 channels of the gastrointestinal nematode Haemonchus contortus. Molecular pharmacology\| PubMed ID: 20679419	2010
A residue close to α1 loop F disrupts modulation of GABAA receptors by benzodiazepines while their binding is maintained. Journal of neurochemistry\| PubMed ID: 20946417	2010
The major central endocannabinoid directly acts at GABA(A) receptors. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 22025726	2011
Influence of GABA(A) receptor α subunit isoforms on the benzodiazepine binding site. PloS one\| PubMed ID: 22848717	2012
Molecular analysis of the site for 2-arachidonylglycerol (2-AG) on the β₂ subunit of GABA(A) receptors. Journal of neurochemistry\| PubMed ID: 23600744	2013
Effects and feasibility of an Integrative Medicine program for geriatric patients-a cluster-randomized pilot study. Clinical interventions in aging\| PubMed ID: 23901266	2013
acr-23 Encodes a monepantel-sensitive channel in Caenorhabditis elegans. PLoS pathogens\| PubMed ID: 23950710	2013
Dementia: treating patients and caregivers with complementary and alternative medicine--results of a clinical expert conference using the World Café method. Forschende Komplementarmedizin (2006)\| PubMed ID: 24030449	2013
Do N-arachidonyl-glycine (NA-glycine) and 2-arachidonoyl glycerol (2-AG) share mode of action and the binding site on the β2 subunit of GABAA receptors? PeerJ\| PubMed ID: 24058880	2013
Accelerated discovery of novel benzodiazepine ligands by experiment-guided virtual screening. ACS chemical biology\| PubMed ID: 24960548	2014
Moderate concentrations of 4-O-methylhonokiol potentiate GABAA receptor currents stronger than honokiol. Biochimica et biophysica acta\| PubMed ID: 24973566	2014
A pentasymmetric open channel blocker for Cys-loop receptor channels. PloS one\| PubMed ID: 25184303	2014
Monepantel irreversibly binds to and opens Haemonchus contortus MPTL-1 and Caenorhabditis elegans ACR-20 receptors. Molecular pharmacology\| PubMed ID: 25352042	2015
Structural analogues of the natural products magnolol and honokiol as potent allosteric potentiators of GABA(A) receptors. Bioorganic & medicinal chemistry\| PubMed ID: 25456080	2014
Positive modulation of synaptic and extrasynaptic GABAA receptors by an antagonist of the high affinity benzodiazepine binding site. Neuropharmacology\| PubMed ID: 25963418	2015
Modulatory Effects of Eschscholzia californica Alkaloids on Recombinant GABAA Receptors. Biochemistry research international\| PubMed ID: 26509084	2015
Functional sites involved in modulation of the GABAA receptor channel by the intravenous anesthetics propofol, etomidate and pentobarbital. Neuropharmacology\| PubMed ID: 26767954	2016
A new chromanone derivative isolated from Hypericum lissophloeus (Hypericaceae) potentiates GABAA receptor currents in a subunit specific fashion. Bioorganic & medicinal chemistry\| PubMed ID: 26791864	2016
Novel positive allosteric modulators of GABAA receptors with anesthetic activity. Scientific reports\| PubMed ID: 27198062	2016
Molecular mode of action of CGS 9895 at α1 β2 γ2 GABAA receptors. Journal of neurochemistry\| PubMed ID: 27319298	2016
Toward Understanding Functional Properties and Subunit Arrangement of α4β2δ γ-Aminobutyric Acid, Type A (GABAA) Receptors. The Journal of biological chemistry\| PubMed ID: 27382064	2016