David Baylink

Division of Regenerative Medicine, Loma Linda University

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 17	2017

Other Publications

Article	Year
Insulin-like growth factor-binding protein 5 (IGFBP-5) interacts with a four and a half LIM protein 2 (FHL2). The Journal of biological chemistry\| PubMed ID: 11821401	2002
Development of a synthetic peptide-based tartrate-resistant acid phosphatase radioimmunoassay for the measurement of bone resorption in rat serum. Journal of bone and mineral metabolism\| PubMed ID: 11862527	2002
DNA microarrays: their use and misuse. Microcirculation (New York, N.Y. : 1994)\| PubMed ID: 11896556	2002
Human osteoblasts' proliferative responses to strain and 17beta-estradiol are mediated by the estrogen receptor and the receptor for insulin-like growth factor I. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research\| PubMed ID: 11924572	2002
Chromosomal regions harboring genes for the work to femur failure in mice. Functional & integrative genomics\| PubMed ID: 11957111	2002
Gene expression between a congenic strain that contains a quantitative trait locus of high bone density from CAST/EiJ and its wild-type strain C57BL/6J. Functional & integrative genomics\| PubMed ID: 11957112	2002
Genetic dissection of femur breaking strength in a large population (MRL/MpJ x SJL/J) of F2 Mice: single QTL effects, epistasis, and pleiotropy. Genomics\| PubMed ID: 11991724	2002
A time course of bone response to jump exercise in C57BL/6J mice. Journal of bone and mineral metabolism\| PubMed ID: 12115066	2002
Quantitative trait loci (QTL) for lean body mass and body length in MRL/MPJ and SJL/J F(2) mice. Functional & integrative genomics\| PubMed ID: 12185457	2002
Quantitative trait loci that harbor genes regulating muscle size in (MRL/MPJ x SJL/J) F(2) mice. Functional & integrative genomics\| PubMed ID: 12185459	2002
Insulin-like growth factor I effect on the number of osteoblast progenitors is impaired in ovariectomized mice. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research\| PubMed ID: 12211427	2002
Differential regulation of pregnancy associated plasma protein (PAPP)-A during pregnancy in human and mouse. Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society\| PubMed ID: 12213189	2002
Effect of low-dose of recombinant human growth hormone on bone metabolism in elderly women with osteoporosis. European journal of endocrinology\| PubMed ID: 12213671	2002
Expression of the fibroblast growth factor receptor genes in fracture repair. Clinical orthopaedics and related research\| PubMed ID: 12360035	2002
Construction of a Tc1-like transposon Sleeping Beauty-based gene transfer plasmid vector for generation of stable transgenic mammalian cell clones. Analytical biochemistry\| PubMed ID: 12413468	2002
ADAM-9 is an insulin-like growth factor binding protein-5 protease produced and secreted by human osteoblasts. Biochemistry\| PubMed ID: 12484779	2002
Serum levels of insulin-like growth factor (IGF)-I and IGF binding protein (IGFBP)-1 to -6 and their relationship to bone metabolism in osteoporosis patients. European journal of internal medicine\| PubMed ID: 12554008	2003
Congenic strains of mice for verification and genetic decomposition of quantitative trait loci for femoral bone mineral density. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research\| PubMed ID: 12568393	2003
Insulin-like growth factor regulates peak bone mineral density in mice by both growth hormone-dependent and -independent mechanisms. Endocrinology\| PubMed ID: 12586770	2003
Fluid flow shear stress stimulates human osteoblast proliferation and differentiation through multiple interacting and competing signal transduction pathways. Bone\| PubMed ID: 12667551	2003
Analytical and clinical evaluation of the Bio-Rad HPLC kit for measurement of type I collagen cross links. Journal of bone and mineral metabolism\| PubMed ID: 12720047	2003
In vivo bone formation in fracture repair induced by direct retroviral-based gene therapy with bone morphogenetic protein-4. Bone\| PubMed ID: 12810166	2003
Mapping quantitative trait loci that influence serum insulin-like growth factor binding protein-5 levels in F2 mice (MRL/MpJ X SJL/J). Endocrinology\| PubMed ID: 12865330	2003
Evidence that sensitivity to growth hormone (GH) is growth period and tissue type dependent: studies in GH-deficient lit/lit mice. Endocrinology\| PubMed ID: 12933669	2003
Expression of a structurally unique osteoclastic protein-tyrosine phosphatase is driven by an alternative intronic, cell type-specific promoter. The Journal of biological chemistry\| PubMed ID: 12949066	2003
Lack of insulin-like growth factor I exaggerates the effect of calcium deficiency on bone accretion in mice. Endocrinology\| PubMed ID: 12960002	2003
A missense mutation in the mouse Col2a1 gene causes spondyloepiphyseal dysplasia congenita, hearing loss, and retinoschisis. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research\| PubMed ID: 12968670	2003
Osteoblastic tartrate-resistant acid phosphatase: its potential role in the molecular mechanism of osteogenic action of fluoride. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research\| PubMed ID: 14584902	2003
Patients with Van Buchem disease, an osteosclerotic genetic disease, have elevated bone formation markers, higher bone density, and greater derived polar moment of inertia than normal. The Journal of clinical endocrinology and metabolism\| PubMed ID: 14671168	2003
Studies on regulation of IGF (insulin-like growth factor)-binding protein (IGFBP) 4 proteolysis by pregnancy-associated plasma protein-A (PAPP-A) in cells treated with phorbol ester. The Biochemical journal\| PubMed ID: 14705967	2004
Local ex vivo gene therapy with bone marrow stromal cells expressing human BMP4 promotes endosteal bone formation in mice. The journal of gene medicine\| PubMed ID: 14716672	2004
Covalent interaction between proform of eosinophil major basic protein (proMBP) and pregnancy-associated plasma protein-A (PAPP-A) is a cell-mediated event and required for proMBP inhibition... Archives of biochemistry and biophysics\| PubMed ID: 15001398	2004
Progress toward skeletal gene therapy. Critical reviews in eukaryotic gene expression\| PubMed ID: 15104530	2004
Sustained elevation of pulsatile growth hormone (GH) secretion and insulin-like growth factor I (IGF-I), IGF-binding protein-3 (IGFBP-3), and IGFBP-5 concentrations during 30-day continuous ... The Journal of clinical endocrinology and metabolism\| PubMed ID: 15126555	2004
HSV-1 amplicon-mediated transfer of 128-kb BMP-2 genomic locus stimulates osteoblast differentiation in vitro. Biochemical and biophysical research communications\| PubMed ID: 15184051	2004
Extracellular signal-regulated kinase-1 and -2 are both essential for the shear stress-induced human osteoblast proliferation. Bone\| PubMed ID: 15268905	2004
Effects of secreted frizzled-related protein 3 on osteoblasts in vitro. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research\| PubMed ID: 15312239	2004
In vivo and in vitro evidence that the high osteoblastic activity in C3H/HeJ mice compared to C57BL/6J mice is intrinsic to bone cells. Bone\| PubMed ID: 15336608	2004
An osteoclastic protein-tyrosine phosphatase may play a role in differentiation and activity of human monocytic U-937 cell-derived, osteoclast-like cells. American journal of physiology. Cell physiology\| PubMed ID: 15355856	2004
Acute effects of calcitonin nasal spray on serum C-telopeptide of type 1 collagen (CTx) levels in elderly osteopenic women with increased bone turnover. Calcified tissue international\| PubMed ID: 15365658	2004
The multi-functional role of insulin-like growth factor binding proteins in bone. Pediatric nephrology (Berlin, Germany)\| PubMed ID: 15549410	2005
Insulin-like growth factor-binding protein-5 induces a gender-related decrease in bone mineral density in transgenic mice. Endocrinology\| PubMed ID: 15550514	2005
Genetic variation in femur extrinsic strength in 29 different inbred strains of mice is dependent on variations in femur cross-sectional geometry and bone density. Bone\| PubMed ID: 15664009	2005
Fluid shear stress synergizes with insulin-like growth factor-I (IGF-I) on osteoblast proliferation through integrin-dependent activation of IGF-I mitogenic signaling pathway. The Journal of biological chemistry\| PubMed ID: 15778506	2005
Isolation of wound healing/regeneration genes using restrictive fragment differential display-PCR in MRL/MPJ and C57BL/6 mice. Biochemical and biophysical research communications\| PubMed ID: 15781240	2005
Bayesian shrinkage estimation of quantitative trait loci parameters. Genetics\| PubMed ID: 15781696	2005
Ibandronate produces significant, similar antifracture efficacy in North American and European women: new clinical findings from BONE. Current medical research and opinion\| PubMed ID: 15811208	2005
Identification of novel genetic loci for bone size and mechanosensitivity in an ENU mutant exhibiting decreased bone size. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research\| PubMed ID: 15883645	2005
Clinical use of serum and urine bone markers in the management of osteoporosis. Current medical research and opinion\| PubMed ID: 16004668	2005
Ras-association domain family 1 protein, RASSF1C, is an IGFBP-5 binding partner and a potential regulator of osteoblast cell proliferation. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research\| PubMed ID: 16007340	2005
Mechanical loading-induced gene expression and BMD changes are different in two inbred mouse strains. Journal of applied physiology (Bethesda, Md. : 1985)\| PubMed ID: 16024522	2005
Spontaneous fractures in the mouse mutant sfx are caused by deletion of the gulonolactone oxidase gene, causing vitamin C deficiency. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research\| PubMed ID: 16059632	2005
Pregnancy-associated plasma protein-A regulates myoblast proliferation and differentiation through an insulin-like growth factor-dependent mechanism. The Journal of biological chemistry\| PubMed ID: 16115888	2005
Global gene expression analysis in the bones reveals involvement of several novel genes and pathways in mediating an anabolic response of mechanical loading in mice. Journal of cellular biochemistry\| PubMed ID: 16149068	2005
New quantitative trait loci that regulate wound healing in an intercross progeny from DBA/1J and 129 x 1/SvJ inbred strains of mice. Functional & integrative genomics\| PubMed ID: 16208538	2006
Quantitative trait loci for femoral and lumbar vertebral bone mineral density in C57BL/6J and C3h/HeJ inbred strains of mice. (2001). Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research\| PubMed ID: 16220609	2005
Identification of quantitative trait loci that regulate obesity and serum lipid levels in MRL/MpJ x SJL/J inbred mice. Journal of lipid research\| PubMed ID: 16254318	2006
An osteoclastic protein-tyrosine phosphatase is a potential positive regulator of the c-Src protein-tyrosine kinase activity: a mediator of osteoclast activity. Journal of cellular biochemistry\| PubMed ID: 16267838	2006
Identification and characterization of novel IGFBP5 interacting protein: evidence IGFBP5-IP is a potential regulator of osteoblast cell proliferation. American journal of physiology. Cell physiology\| PubMed ID: 16269403	2006
Microarray analysis of gene expression during the inflammation and endochondral bone formation stages of rat femur fracture repair. Bone\| PubMed ID: 16321582	2006
Mapping the dominant wound healing and soft tissue regeneration QTL in MRL x CAST. Mammalian genome : official journal of the International Mammalian Genome Society\| PubMed ID: 16341671	2005
Multiple genetic loci from CAST/EiJ chromosome 1 affect vBMD either positively or negatively in a C57BL/6J background. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research\| PubMed ID: 16355278	2006
Up-regulation of the Wnt, estrogen receptor, insulin-like growth factor-I, and bone morphogenetic protein pathways in C57BL/6J osteoblasts as opposed to C3H/HeJ osteoblasts in part contribut... The Journal of biological chemistry\| PubMed ID: 16461770	2006
Whole genome microarray analysis of growth hormone-induced gene expression in bone: T-box3, a novel transcription factor, regulates osteoblast proliferation. American journal of physiology. Endocrinology and metabolism\| PubMed ID: 16464905	2006
Identification of genetic loci that regulate bone adaptive response to mechanical loading in C57BL/6J and C3H/HeJ mice intercross. Bone\| PubMed ID: 16713414	2006
Femur mechanical properties in the F2 progeny of an NZB/B1NJ x RF/J cross are regulated predominantly by genetic loci that regulate bone geometry. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research\| PubMed ID: 16869724	2006
A platform of high-efficiency nonviral gene transfer in mouse osteoblast cells in vitro. Molecular biotechnology\| PubMed ID: 16943568	2006
Pregnancy-associated plasma protein-A increases osteoblast proliferation in vitro and bone formation in vivo. Endocrinology\| PubMed ID: 16946002	2006
An improved mouse Sca-1+ cell-based bone marrow transplantation model for use in gene- and cell-based therapeutic studies. Acta haematologica\| PubMed ID: 17095856	2007
Modifications of the fibroblast growth factor-2 gene led to a marked enhancement in secretion and stability of the recombinant fibroblast growth factor-2 protein. Journal of cellular biochemistry\| PubMed ID: 17243099	2007
The selective cyclooxygenase-2 inhibitor celecoxib reduces bone resorption, but not bone formation, in ovariectomized mice in vivo. The Tohoku journal of experimental medicine\| PubMed ID: 17347553	2007
Digit tip regrowth and differential gene expression in MRL/Mpj, DBA/2, and C57BL/6 mice. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society\| PubMed ID: 17352761	2007
A transmembrane osteoclastic protein-tyrosine phosphatase regulates osteoclast activity in part by promoting osteoclast survival through c-Src-dependent activation of NFkappaB and JNK2. Archives of biochemistry and biophysics\| PubMed ID: 17400176	2007
Identification of mouse Duffy antigen receptor for chemokines (Darc) as a BMD QTL gene. Genome research\| PubMed ID: 17416748	2007
Mapping genetic loci that regulate lipid levels in a NZB/B1NJxRF/J intercross and a combined intercross involving NZB/B1NJ, RF/J, MRL/MpJ, and SJL/J mouse strains. Journal of lipid research\| PubMed ID: 17496333	2007
Nuclear factor-E2-related factor-1 mediates ascorbic acid induction of osterix expression via interaction with antioxidant-responsive element in bone cells. The Journal of biological chemistry\| PubMed ID: 17510056	2007
Disruption of insulin-like growth factor-I expression in type IIalphaI collagen-expressing cells reduces bone length and width in mice. Physiological genomics\| PubMed ID: 17519362	2007
Novel loci regulating bone anabolic response to loading: expression QTL analysis in C57BL/6JXC3H/HeJ mice cross. Bone\| PubMed ID: 17543594	2007
Sca-1(+) hematopoietic cell-based gene therapy with a modified FGF-2 increased endosteal/trabecular bone formation in mice. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 17637718	2007
Conditional deletion of insulin-like growth factor-I in collagen type 1alpha2-expressing cells results in postnatal lethality and a dramatic reduction in bone accretion. Endocrinology\| PubMed ID: 17717052	2007
Mouse chromosome 9 quantitative trait loci for soft tissue regeneration: congenic analysis and fine mapping. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society\| PubMed ID: 18028142	2007
A chemical mutagenesis screen to identify modifier genes that interact with growth hormone and TGF-beta signaling pathways. Bone\| PubMed ID: 18063435	2008
Retroviral-based gene therapy with cyclooxygenase-2 promotes the union of bony callus tissues and accelerates fracture healing in the rat. The journal of gene medicine\| PubMed ID: 18088065	2008
Mapping of the chromosome 17 BMD QTL in the F(2) male mice of MRL/MpJ x SJL/J. Genetica\| PubMed ID: 18330711	2009
Quantitative trait loci, genes, and polymorphisms that regulate bone mineral density in mouse. Genomics\| PubMed ID: 19150398	2009
Marrow stromal cell-based cyclooxygenase 2 ex vivo gene-transfer strategy surprisingly lacks bone-regeneration effects and suppresses the bone-regeneration action of bone morphogenetic prote... Calcified tissue international\| PubMed ID: 19763374	2009
Prevention of colorectal cancer with vitamin D. Scandinavian journal of gastroenterology\| PubMed ID: 20367197	2010
Leptin receptor (Lepr) is a negative modulator of bone mechanosensitivity and genetic variations in Lepr may contribute to the differential osteogenic response to mechanical stimulation in t... The Journal of biological chemistry\| PubMed ID: 20851886	2010
Efficient Reprogramming of Human Cord Blood CD34(+) Cells Into Induced Pluripotent Stem Cells With OCT4 and SOX2 Alone. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 22108860	2012
Targeted overexpression of osteoactivin in cells of osteoclastic lineage promotes osteoclastic resorption and bone loss in mice. PloS one\| PubMed ID: 22536365	2012
Erythroid promoter confines FGF2 expression to the marrow after hematopoietic stem cell gene therapy and leads to enhanced endosteal bone formation. PloS one\| PubMed ID: 22629419	2012
Transgenic overexpression of pregnancy-associated plasma protein-A in skeletal muscle of mice increases myofiber size and central nucleation in sedentary muscle and promotes muscle regenerat... Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society\| PubMed ID: 22709655	2012
Disruption of the insulin-like growth factor-1 gene in osteocytes impairs developmental bone growth in mice. Bone\| PubMed ID: 23032105	2013
Cellular and molecular mechanisms of accelerated fracture healing by COX2 gene therapy: Studies in a mouse model of multiple fractures. Bone\| PubMed ID: 23314071	2013
Rapid and efficient reprogramming of human fetal and adult blood CD34+ cells into mesenchymal stem cells with a single factor. Cell research\| PubMed ID: 23478301	2013
1,25-Dihydroxyvitamin D3 suppresses TLR8 expression and TLR8-mediated inflammatory responses in monocytes in vitro and experimental autoimmune encephalomyelitis in vivo. PloS one\| PubMed ID: 23516559	2013
Efficient generation of integration-free ips cells from human adult peripheral blood using BCL-XL together with Yamanaka factors. PloS one\| PubMed ID: 23704989	2013
Osteocyte-derived insulin-like growth factor I is essential for determining bone mechanosensitivity. American journal of physiology. Endocrinology and metabolism\| PubMed ID: 23715728	2013
Serum 1,25-dihydroxyvitamin D: an outcome prognosticator in human sepsis. PloS one\| PubMed ID: 23741318	2013
ENU mutation mapped to a distal region of chromosome 11 is a major determinant of bone size. Physiological genomics\| PubMed ID: 24151243	2013
Maternal infection with Schistosoma japonicum induces a profibrotic response in neonates. Infection and immunity\| PubMed ID: 24166958	2014
Characterization of an animal model of pregnancy-induced vitamin D deficiency due to metabolic gene dysregulation. American journal of physiology. Endocrinology and metabolism\| PubMed ID: 24326417	2014
Role of Osteocyte-derived Insulin-Like Growth Factor I in Developmental Growth, Modeling, Remodeling, and Regeneration of the Bone. Journal of bone metabolism\| PubMed ID: 24707466	2014
Targeted 25-hydroxyvitamin D3 1α-hydroxylase adoptive gene therapy ameliorates dss-induced colitis without causing hypercalcemia in mice. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 25327179	2015
Osteocyte-derived insulin-like growth factor I is not essential for the bone repletion response in mice. PloS one\| PubMed ID: 25635763	2015
Generation of Mesenchymal Stem Cells by Blood Cell Reprogramming. Current stem cell research & therapy\| PubMed ID: 26027679	2016
PDGFB-based stem cell gene therapy increases bone strength in the mouse. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 26150503	2015
Patient-specific cardiovascular progenitor cells derived from integration-free induced pluripotent stem cells for vascular tissue regeneration. Biomaterials\| PubMed ID: 26398309	2015
MicroRNA223 promotes pathogenic T-cell development and autoimmune inflammation in central nervous system in mice. Immunology\| PubMed ID: 27083389	2016
Vitamin D status and metabolism in an ovine pregnancy model: effect of long-term, high-altitude hypoxia. American journal of physiology. Endocrinology and metabolism\| PubMed ID: 27143557	2016
Conditional deletion of IGF-I in osteocytes unexpectedly accelerates bony union of the fracture gap in mice. Bone\| PubMed ID: 27519969	2016
Targeting Non-classical Myelin Epitopes to Treat Experimental Autoimmune Encephalomyelitis. Scientific reports\| PubMed ID: 27796368	2016