Hong Zan

Department of Microbiology, University of Texas Long School of Medicine at San Antonio

Affiliated withUniversity of Texas Long School of Medicine at San Antonio

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 2	2017

Other Publications

Article	Year
Chronic lymphocytic leukemia B cells can undergo somatic hypermutation and intraclonal immunoglobulin V(H)DJ(H) gene diversification. The Journal of experimental medicine\| PubMed ID: 12208878	2002
Ongoing in vivo immunoglobulin class switch DNA recombination in chronic lymphocytic leukemia B cells. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 12444172	2002
Selective inhibition of class switching to IgG and IgE by recruitment of the HoxC4 and Oct-1 homeodomain proteins and Ku70/Ku86 to newly identified ATTT cis-elements. The Journal of biological chemistry\| PubMed ID: 12672812	2003
AID-dependent generation of resected double-strand DNA breaks and recruitment of Rad52/Rad51 in somatic hypermutation. Immunity\| PubMed ID: 12818155	2003
Immunoglobulin somatic hypermutation: double-strand DNA breaks, AID and error-prone DNA repair. Journal of clinical immunology\| PubMed ID: 12959216	2003
Class switching and Myc translocation: how does DNA break? Nature immunology\| PubMed ID: 15496946	2004
DNA lesions and repair in immunoglobulin class switch recombination and somatic hypermutation. Annals of the New York Academy of Sciences\| PubMed ID: 16014529	2005
The translesion DNA polymerase theta plays a dominant role in immunoglobulin gene somatic hypermutation. The EMBO journal\| PubMed ID: 16222339	2005
Biased dA/dT somatic hypermutation as regulated by the heavy chain intronic iEmu enhancer and 3'Ealpha enhancers in human lymphoblastoid B cells. Molecular immunology\| PubMed ID: 16412510	2006
A role for the MutL mismatch repair Mlh3 protein in immunoglobulin class switch DNA recombination and somatic hypermutation. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 16622010	2006
DNA repair in antibody somatic hypermutation. Trends in immunology\| PubMed ID: 16737852	2006
DNA replication to aid somatic hypermutation. Advances in experimental medicine and biology\| PubMed ID: 17338180	2007
Regulation of aicda expression and AID activity: relevance to somatic hypermutation and class switch DNA recombination. Critical reviews in immunology\| PubMed ID: 18197815	2007
A role for DRAK2 in the germinal center reaction and the antibody response. Autoimmunity\| PubMed ID: 18568639	2008
AID- and Ung-dependent generation of staggered double-strand DNA breaks in immunoglobulin class switch DNA recombination: a post-cleavage role for AID. Molecular immunology\| PubMed ID: 18760480	2008
Lupus-prone MRL/faslpr/lpr mice display increased AID expression and extensive DNA lesions, comprising deletions and insertions, in the immunoglobulin locus: concurrent upregulation of somat... Autoimmunity\| PubMed ID: 19156553	2009
HoxC4 binds to the promoter of the cytidine deaminase AID gene to induce AID expression, class-switch DNA recombination and somatic hypermutation. Nature immunology\| PubMed ID: 19363484	2009
Toll-like receptors and B-cell receptors synergize to induce immunoglobulin class-switch DNA recombination: relevance to microbial antibody responses. Critical reviews in immunology\| PubMed ID: 20370617	2010
14-3-3 adaptor proteins recruit AID to 5'-AGCT-3'-rich switch regions for class switch recombination. Nature structural & molecular biology\| PubMed ID: 20729863	2010
Specific cross-reaction of anti-dsDNA antibody with platelet integrin GPIIIa49-66. Autoimmunity\| PubMed ID: 20828249	2010
Estrogen receptors bind to and activate the HOXC4/HoxC4 promoter to potentiate HoxC4-mediated activation-induced cytosine deaminase induction, immunoglobulin class switch DNA recombination, ... The Journal of biological chemistry\| PubMed ID: 20855884	2010
Three fatal cases of pandemic 2009 influenza A virus infection in Shenzhen are associated with cytokine storm. Respiratory physiology & neurobiology\| PubMed ID: 21075220	2011
Endonuclease G plays a role in immunoglobulin class switch DNA recombination by introducing double-strand breaks in switch regions. Molecular immunology\| PubMed ID: 21111482	2011
AID dysregulation in lupus-prone MRL/Fas(lpr/lpr) mice increases class switch DNA recombination and promotes interchromosomal c-Myc/IgH loci translocations: modulation by HoxC4. Autoimmunity\| PubMed ID: 21585311	2011
Viral kinetics of enterovirus 71 in human abdomyosarcoma cells. World journal of gastroenterology\| PubMed ID: 22039330	2011
BCR-signalling synergizes with TLR-signalling for induction of AID and immunoglobulin class-switching through the non-canonical NF-κB pathway. Nature communications\| PubMed ID: 22473011	2012
B cell TLRs and induction of immunoglobulin class-switch DNA recombination. Frontiers in bioscience (Landmark edition)\| PubMed ID: 22652800	2012
Immunoglobulin class-switch DNA recombination: induction, targeting and beyond. Nature reviews. Immunology\| PubMed ID: 22728528	2012
Rev1 recruits ung to switch regions and enhances du glycosylation for immunoglobulin class switch DNA recombination. Cell reports\| PubMed ID: 23140944	2012
Regulation of Aicda expression and AID activity. Autoimmunity\| PubMed ID: 23181381	2013
Epigenetics of the antibody response. Trends in immunology\| PubMed ID: 23643790	2013
Combinatorial H3K9acS10ph histone modification in IgH locus S regions targets 14-3-3 adaptors and AID to specify antibody class-switch DNA recombination. Cell reports\| PubMed ID: 24209747	2013
MicroRNAs in lupus. Autoimmunity\| PubMed ID: 24826805	2014
Epigenetics in lupus. Autoimmunity\| PubMed ID: 24826881	2014
Histone deacetylase inhibitors upregulate B cell microRNAs that silence AID and Blimp-1 expression for epigenetic modulation of antibody and autoantibody responses. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 25392531	2014
Genome-Wide Analysis Reveals Selective Modulation of microRNAs and mRNAs by Histone Deacetylase Inhibitor in B Cells Induced to Undergo Class-Switch DNA Recombination and Plasma Cell Differe... Frontiers in immunology\| PubMed ID: 26697020	2015
Epigenetics of Peripheral B-Cell Differentiation and the Antibody Response. Frontiers in immunology\| PubMed ID: 26697022	2015
Editorial: Epigenetics of B Cells and Antibody Responses. Frontiers in immunology\| PubMed ID: 26793194	2015
Small Molecule Inhibition of Rab7 Impairs B Cell Class Switching and Plasma Cell Survival To Dampen the Autoantibody Response in Murine Lupus. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 27742832	2016
Rad52 competes with Ku70/Ku86 for binding to S-region DSB ends to modulate antibody class-switch DNA recombination. Nature communications\| PubMed ID: 28176781	2017