Joris Vriens

Joris Vriens

Department of Development and Regeneration, Katholieke Universiteit Leuven (KU Leuven)

Affiliated withKatholieke Universiteit Leuven (KU Leuven)KU Leuven

Research Area

Biography

Joris Vriens is Full Professor at the Department Development & Regeneration at the University of Leuven in Belgium. He received his PhD in Biomedical Sciences at the University of Leuven investigating the different activation mechanism of the TRPV4 ion channel. As a post doctoral researcher he went abroad to the lab of Prof Clapham at the Harvard Medical School, Boston, US to assess the Total Internal Reflection Fluorescence Microscopy to study the trafficking of ion channels to the plasma membrane. After his post doc period he returned to the lab of ion channel research where he initiated new research projects on TRPM3. Together with prof Voets he characterized TRPM3 as an important nociceptor in the peripheral nerve system and an interesting target for the development of novel analgesics for the treatment of different types of pain. In 2011, Vriens became the head of the lab of endometrium, endometriosis and reproductive medicine (LEERM) at the Leuven University. His research group continues to pioneer and investigate the role of ion channels in the female reproductive system with a particular focus on endometrial receptivity and assess the role of ion channels in placental function and development. The lab of Vriens is part of the Center of Ion Channel Research headed by Prof Voets.

JoVE Journal Publications

ArticleTotal : 2
Year
Isolation of Mouse Endometrial Epithelial and Stromal Cells for <em>In Vitro</em> Decidualization
Publication title

Cited by 86

2017
2020

Other Publications

Article
Year
Activation of TRPV4 channels (hVRL-2/mTRP12) by phorbol derivatives.

The Journal of biological chemistry| PubMed ID: 11827975

2002
Molecular determinants of permeation through the cation channel TRPV4.

The Journal of biological chemistry| PubMed ID: 12093812

2002
2002
The TRPV4 channel: structure-function relationship and promiscuous gating behaviour.

Pflugers Archiv : European journal of physiology| PubMed ID: 12715179

2003
2003
2003
TRPV4 calcium entry channel: a paradigm for gating diversity.

American journal of physiology. Cell physiology| PubMed ID: 14707014

2004
2004
Invertebrate TRP proteins as functional models for mammalian channels.

Pflugers Archiv : European journal of physiology| PubMed ID: 15480752

2004
2007
2007
2007
2008
2008
2008
2009
2009
Herbal compounds and toxins modulating TRP channels.

Current neuropharmacology| PubMed ID: 19305789

2008
2009
Functional characterization of transient receptor potential channels in mouse urothelial cells.

American journal of physiology. Renal physiology| PubMed ID: 20015940

2010
Dominant TRPV4 mutations in nonlethal and lethal metatropic dysplasia.

American journal of medical genetics. Part A| PubMed ID: 20425821

2010
Inhibition of the cation channel TRPV4 improves bladder function in mice and rats with cyclophosphamide-induced cystitis.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 20956320

2010
2011
2012
2012
2012
2014
Peripheral thermosensation in mammals.

Nature reviews. Neuroscience| PubMed ID: 25053448

2014
2015
Activation of TRPM3 by a potent synthetic ligand reveals a role in peptide release.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 25733887

2015
2015
2015
Signature and Pathophysiology of Non-canonical Pores in Voltage-Dependent Cation Channels.

Reviews of physiology, biochemistry and pharmacology| PubMed ID: 26791748

2016
2016
Urine of Preterm Neonates as a Novel Source of Kidney Progenitor Cells.

Journal of the American Society of Nephrology : JASN| PubMed ID: 26940093

2016
Laparoscopic Surgery: A New Technique to Induce Endometriosis in a Mouse Model.

Reproductive sciences (Thousand Oaks, Calif.)| PubMed ID: 26994066

2016
TRPM3 in temperature sensing and beyond.

Temperature (Austin, Tex.)| PubMed ID: 27227024

2015
TRPV4 is associated with central rather than nephrogenic osmoregulation.

Pflugers Archiv : European journal of physiology| PubMed ID: 27364478

2016
2016
2016
2017
2016
TRP channel pores and local calcium signals.

Cell calcium| PubMed ID: 28807146

2017
Of Mice and Women: A Laparoscopic Mouse Model for Endometriosis.

Journal of minimally invasive gynecology| PubMed ID: 29032250

2018
Sensing the heat with TRPM3.

Pflugers Archiv : European journal of physiology| PubMed ID: 29305649

2018
2018
2018
2018
2019
Establishing life is a calcium-dependent TRiP: Transient receptor potential channels in reproduction.

Biochimica et biophysica acta. Molecular cell research| PubMed ID: 30798946

2018
High-resolution contrast-enhanced microCT reveals the true three-dimensional morphology of the murine placenta.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 31249139

2019
2019
Heat sensing involves a TRiPlet of ion channels.

British journal of pharmacology| PubMed ID: 31372975

2019
2019
2020
The Sensory Coding of Warm Perception.

Neuron| PubMed ID: 32208171

2020
2020
2020
2020
2020
2020
2020