Ernst Klar

Department of General, Rostock University Medical Center

Affiliated withRostock University Medical Center

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 4	2017

Other Publications

Article	Year
Transformation of the microvascular system during multistage tumorigenesis. International journal of cancer\| PubMed ID: 11857345	2002
Immunoprophylaxis with basiliximab, a chimeric anti-interleukin-2 receptor monoclonal antibody, in combination with azathioprine-containing triple therapy in liver transplant recipients. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society\| PubMed ID: 11862588	2002
Detection of disseminated medullary thyroid carcinoma cells in cervical lymph nodes by cytokeratin 20 reverse transcription-polymerase chain reaction. World journal of surgery\| PubMed ID: 11865340	2002
Combination of T-cell therapy and trigger of inflammation induces remodeling of the vasculature and tumor eradication. Cancer research\| PubMed ID: 11888921	2002
Reduction in mortality with delayed surgical therapy of severe pancreatitis. Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract\| PubMed ID: 12023003	2002
Ischemic preconditioning by brief extremity ischemia before flap ischemia in a rat model. Plastic and reconstructive surgery\| PubMed ID: 12045567	2002
Pancreatic capillary blood flow in an improved model of necrotizing pancreatitis in the rat. The Journal of surgical research\| PubMed ID: 12175989	2002
Primary colorectal carcinomas and their intrapulmonary metastases: clinical, glyco-, immuno- and lectin histochemical, nuclear and syntactic structure analysis with emphasis on correlation w... APMIS : acta pathologica, microbiologica, et immunologica Scandinavica\| PubMed ID: 12193204	2002
Detection of hematogenic and lymphogenic tumor cell dissemination in patients with medullary thyroid carcinoma by cytokeratin 20 and preprogastrin-releasing peptide RT-PCR. International journal of cancer\| PubMed ID: 12455065	2003
Limits of Couinaud's liver segment classification: a quantitative computer-based three-dimensional analysis. Journal of computer assisted tomography\| PubMed ID: 12488744	2002
RET proto-oncogene mutations affecting codon 790/791: A mild form of multiple endocrine neoplasia type 2A syndrome? Surgery\| PubMed ID: 12490841	2002
Different radiogenic effects on microcirculation in healthy pancreas and in pancreatic carcinoma of the rat. Annals of surgery\| PubMed ID: 12677148	2003
Radiation-induced leukocyte adhesion to endothelium in normal pancreas and in pancreatic carcinoma of the rat. International journal of cancer\| PubMed ID: 12712442	2003
Assessment of renal graft function by perioperative monitoring of cortical microcirculation in kidney transplantation. Transplantation\| PubMed ID: 12717202	2003
Oxygen radicals promote ICAM-1 expression and microcirculatory disturbances in experimental acute pancreatitis. Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]\| PubMed ID: 12748425	2003
Primary human hepatocytes--a valuable tool for investigation of apoptosis and hepatitis B virus infection. Journal of hepatology\| PubMed ID: 12763365	2003
Donor pretreatment with gadolinium chloride improves early graft function and survival after porcine liver transplantation. Transplant international : official journal of the European Society for Organ Transplantation\| PubMed ID: 12879229	2003
Detection and prognostic relevance of cytokeratin 20 in differentiated and anaplastic thyroid carcinomas by RT-PCR. Surgery\| PubMed ID: 14668729	2003
Effects of heparin in experimental models of acute pancreatitis and post-ERCP pancreatitis. Surgery\| PubMed ID: 14739847	2004
C1-inhibitor reduces hepatic leukocyte-endothelial interaction and the expression of VCAM-1 in LPS-induced sepsis in the rat. Microvascular research\| PubMed ID: 15020209	2004
Expansion of endothelial surface by an increase of vessel diameter during tumor angiogenesis in experimental and hepatocellular and pancreatic cancer. World journal of gastroenterology\| PubMed ID: 15457566	2004
The effect of adenovirus expressing wild-type p53 on 5-fluorouracil chemosensitivity is related to p53 status in pancreatic cancer cell lines. World journal of gastroenterology\| PubMed ID: 15534911	2004
Neoadjuvant radiochemotherapy in locally advanced gastric carcinoma. Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]\| PubMed ID: 15549187	2004
Control of T-cell-mediated immune response by HLA class I in human pancreatic carcinoma. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 15701833	2005
Identification of differentially expressed genes after partial rat liver ischemia/reperfusion by suppression subtractive hybridization. World journal of gastroenterology\| PubMed ID: 15761968	2005
Sustained hypothermia accelerates microvascular thrombus formation in mice. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 16100248	2005
Axillary-axillary interarterial chest loop conduit as an alternative for chronic hemodialysis access. Journal of vascular surgery\| PubMed ID: 16102629	2005
HEGPOL: randomized, placebo controlled, multicenter, double-blind clinical trial to investigate hepatoprotective effects of glycine in the postoperative phase of liver transplantation [ISRCT... BMC surgery\| PubMed ID: 16105183	2005
Hepatic platelet and leukocyte adherence during endotoxemia. Critical care (London, England)\| PubMed ID: 16420661	2006
Ciclosporin aggravates tissue damage in ischemia reperfusion-induced acute pancreatitis. Pancreas\| PubMed ID: 16552333	2006
Activating anti-CD40 antibodies induce tumour invasion by cytotoxic T-lymphocytes and inhibition of tumour growth in experimental liver cancer. European journal of cancer (Oxford, England : 1990)\| PubMed ID: 16564167	2006
Postoperative chemotherapy may not be necessary for patients with ypN0-category after neoadjuvant chemoradiotherapy of rectal cancer. Diseases of the colon and rectum\| PubMed ID: 16758130	2006
Iliac anastomotic stenting with a biodegradable poly-L-lactide stent: a preliminary study after 1 and 6 weeks. Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists\| PubMed ID: 16928171	2006
Penetration of moxifloxacin into the human pancreas following a single intravenous or oral dose. The Journal of antimicrobial chemotherapy\| PubMed ID: 16956903	2006
Effective antitumoral immune responses are not induced by cytosine deaminase suicide gene transfer in a syngeneic rat pancreatic carcinoma model. European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes\| PubMed ID: 17028434	2006
Iliac anastomotic stenting with a sirolimus-eluting biodegradable poly-L-lactide stent: a preliminary study after 6 weeks. Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists\| PubMed ID: 17042669	2006
Dynamic changes of post-ischemic hepatic microcirculation improved by a pre-treatment of phosphodiesterase-3 inhibitor, milrinone. The Journal of surgical research\| PubMed ID: 17045613	2006
Systemic hypothermia increases PAI-1 expression and accelerates microvascular thrombus formation in endotoxemic mice. Critical care (London, England)\| PubMed ID: 17062126	2006
Sirolimus-eluting biodegradable poly-L-lactide stent for peripheral vascular application: a preliminary study in porcine carotid arteries. The Journal of surgical research\| PubMed ID: 17292417	2007
Darbepoetin-alpha does not promote microvascular thrombus formation in mice: role of eNOS-dependent protection through platelet and endothelial cell deactivation. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 17347485	2007
Distinct effects of acute and chronic nicotine application on microvascular thrombus formation and endothelial function in male and female mice. Langenbeck's archives of surgery / Deutsche Gesellschaft für Chirurgie\| PubMed ID: 17384961	2007
Effect of parathyroidectomy on quality of life and neuropsychological symptoms in primary hyperparathyroidism. World journal of surgery\| PubMed ID: 17460812	2007
Effect of neoadjuvant chemoradiation on postoperative fecal continence and anal sphincter function in rectal cancer patients. International journal of colorectal disease\| PubMed ID: 17497160	2007
Induction of an antitumoral immune response by wild-type adeno-associated virus type 2 in an in vivo model of pancreatic carcinoma. Pancreas\| PubMed ID: 17575547	2007
A biodegradable stent based on poly(L-lactide) and poly(4-hydroxybutyrate) for peripheral vascular application: preliminary experience in the pig. Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists\| PubMed ID: 17924740	2007
Intensified irinotecan-based neoadjuvant chemoradiotherapy in rectal cancer: four consecutive designed studies to minimize acute toxicity and to optimize efficacy measured by pathologic comp... Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology\| PubMed ID: 18036687	2007
Primary human hepatocytes are protected against complement by multiple regulators. Molecular immunology\| PubMed ID: 19446335	2009
Quantification of liver perfusion by dynamic magnetic resonance imaging: experimental evaluation and clinical pilot study. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society\| PubMed ID: 19562702	2009
Postoperative care following pancreatic surgery: surveillance and treatment. Deutsches Arzteblatt international\| PubMed ID: 20038981	2009
Microvascular dysfunction in hepatic ischemia-reperfusion injury in pigs. Microvascular research\| PubMed ID: 20184903	2010
Generation of highly pure fusions of colorectal carcinoma and antigen-presenting cells. Langenbeck's archives of surgery\| PubMed ID: 20309577	2010
Identification of an MSI-H tumor-specific cytotoxic T cell epitope generated by the (-1) frame of U79260(FTO). Journal of biomedicine & biotechnology\| PubMed ID: 20339516	2010
Induction of HSP70 shows differences in protection against I/R injury derived by ischemic preconditioning and intermittent clamping. Microvascular research\| PubMed ID: 20478315	2010
Cryopreservation of human colorectal carcinomas prior to xenografting. BMC cancer\| PubMed ID: 20615215	2010
Bacteriolytic therapy of experimental pancreatic carcinoma. World journal of gastroenterology\| PubMed ID: 20653063	2010
Laparoscopic treatment of renal artery entrapment. Journal of vascular surgery\| PubMed ID: 20678884	2010
Pharmacokinetics and penetration of moxifloxacin into infected diabetic foot tissue in a large diabetic patient cohort. European journal of clinical pharmacology\| PubMed ID: 20871984	2011
Extracorporeal cell therapy of septic shock patients with donor granulocytes: a pilot study. Critical care (London, England)\| PubMed ID: 21371308	2011
Impact of portal branch ligation on tissue regeneration, microcirculatory response and microarchitecture in portal blood-deprived and undeprived liver tissue. Microvascular research\| PubMed ID: 21397614	2011
DTG procurement guidelines in heart beating donors. Transplant international : official journal of the European Society for Organ Transplantation\| PubMed ID: 21668528	2011
Multidrug-resistance proteins are weak tumor associated antigens for colorectal carcinoma. BMC immunology\| PubMed ID: 21740599	2011
Multidrug strategies are effective in the treatment of severe experimental pancreatitis. Surgery\| PubMed ID: 21982067	2012
Immunosuppressants accelerate microvascular thrombus formation in vivo: role of endothelial cell activation. Surgery\| PubMed ID: 22019501	2012
Bacterial immunotherapy of gastrointestinal tumors. Langenbeck's archives of surgery\| PubMed ID: 22189906	2012
Combining bacterial-immunotherapy with therapeutic antibodies: a novel therapeutic concept. Vaccine\| PubMed ID: 22342917	2012
Treatment of necrotizing pancreatitis: redefining the role of surgery. World journal of surgery\| PubMed ID: 22382765	2012
Ex-vivo clonally expanded B lymphocytes infiltrating colorectal carcinoma are of mature immunophenotype and produce functional IgG. PloS one\| PubMed ID: 22393427	2012
Acute mesenteric ischemia: a vascular emergency. Deutsches Arzteblatt international\| PubMed ID: 22536301	2012
A novel sialyl Le(X) expression score as a potential prognostic tool in colorectal cancer. World journal of surgical oncology\| PubMed ID: 22621806	2012
Volume-outcome relationship in pancreatic surgery: the situation in Germany. Surgery\| PubMed ID: 22763260	2012
R1 resection in pancreatic cancer has significant impact on long-term outcome in standardized pathology modified for routine use. Surgery\| PubMed ID: 22766366	2012
The "North German Tumor Bank of Colorectal Cancer": status report after the first 2 years of support by the German Cancer Aid Foundation. Langenbeck's archives of surgery / Deutsche Gesellschaft für Chirurgie\| PubMed ID: 23292500	2013
Reperfusion of liver graft during transplantation: techniques used in transplant centres within Eurotransplant and meta-analysis of the literature. Transplant international : official journal of the European Society for Organ Transplantation\| PubMed ID: 23517278	2013
Is the lymph node ratio superior to the Union for International Cancer Control (UICC) TNM system in prognosis of colon cancer? World journal of surgical oncology\| PubMed ID: 23521843	2013
Scoring of human acute pancreatitis: state of the art. Langenbeck's archives of surgery\| PubMed ID: 23680979	2013
Prognosis of rectal cancer patients improves with downstaging by intensified neoadjuvant radiochemotherapy - a matched pair analysis. BMC cancer\| PubMed ID: 23947828	2013
Acute cholecystitis: early versus delayed cholecystectomy, a multicenter randomized trial (ACDC study, NCT00447304). Annals of surgery\| PubMed ID: 24022431	2013
Intensified neoadjuvant radiochemotherapy for rectal cancer enhances surgical complications. BMC surgery\| PubMed ID: 24073705	2013
Future perspectives for surgical research in Germany. Langenbeck's archives of surgery\| PubMed ID: 24615143	2014
Host defense peptides for treatment of colorectal carcinoma - a comparative in vitro and in vivo analysis. Oncotarget\| PubMed ID: 24962950	2014
Gastric gastrointestinal stromal tumor lost in the peritoneum after endoscopic resection. Endoscopy\| PubMed ID: 25121627	2014
VEGF-releasing suture material for enhancement of vascularization: development, in vitro and in vivo study. Acta biomaterialia\| PubMed ID: 25204522	2014
Endoscopic continuity-preserving therapy for esophageal stenosis and perforation following colliquative necrosis. Endoscopy\| PubMed ID: 25254576	2014
Establishment and characterization of cell lines from chromosomal instable colorectal cancer. World journal of gastroenterology\| PubMed ID: 25574089	2015
Reactivity against microsatellite instability-induced frameshift mutations in patients with inflammatory bowel disease. World journal of gastroenterology\| PubMed ID: 25574094	2015
Graft rinse prior to reperfusion in liver transplantation: literature review and online survey within the Eurotransplant community. Transplant international : official journal of the European Society for Organ Transplantation\| PubMed ID: 26147505	2015
Optimizing the process of nucleofection for professional antigen presenting cells. BMC research notes\| PubMed ID: 26404473	2015
Inflammatory Bowel Diseases: Current Medical and Surgical Therapy. Viszeralmedizin\| PubMed ID: 26557829	2015
Surgical Principles in the Treatment of Ulcerative Colitis. Viszeralmedizin\| PubMed ID: 26557832	2015
Endoscopic Vacuum Therapy in Colorectal Surgery. Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract\| PubMed ID: 26597270	2016
Functional Characterization and Drug Response of Freshly Established Patient-Derived Tumor Models with CpG Island Methylator Phenotype. PloS one\| PubMed ID: 26618628	2015
Surgical Endoscopic Vacuum Therapy for Defects of the Upper Gastrointestinal Tract. Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract\| PubMed ID: 26643296	2016
Ectopic Spleen Tissue - an Underestimated Differential Diagnosis of a Hypervascularised Liver Tumour. Viszeralmedizin\| PubMed ID: 26889148	2015
Establishment and characterization of HROC69 - a Crohn´s related colonic carcinoma cell line and its matched patient-derived xenograft. Scientific reports\| PubMed ID: 27087592	2016
Differential effects of endogenous, phyto and synthetic cannabinoids on thrombogenesis and platelet activity. BioFactors (Oxford, England)\| PubMed ID: 27151562	2016
The mutational profile and infiltration pattern of murine MLH1-/- tumors: concurrences, disparities and cell line establishment for functional analysis. Oncotarget\| PubMed ID: 27447752	2016
Extending the Limits of Resection for Colorectal Liver Metastases. Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract\| PubMed ID: 27619805	2017
Open Surgical versus Minimal Invasive Necrosectomy of the Pancreas-A Retrospective Multicenter Analysis of the German Pancreatitis Study Group. PloS one\| PubMed ID: 27668746	2016
The effects of hydrogen sulfide on platelet-leukocyte aggregation and microvascular thrombolysis. Platelets\| PubMed ID: 27819526	2016
Tumor Take Rate Optimization for Colorectal Carcinoma Patient-Derived Xenograft Models. BioMed research international\| PubMed ID: 27999790	2016
Endoscopic vacuum therapy for various defects of the upper gastrointestinal tract. Surgical endoscopy\| PubMed ID: 28078463	2017