Kinya Hotta

School of Biosciences, The University of Nottingham Malaysia Campus

Affiliated withThe University of Nottingham Malaysia Campus

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2017

Other Publications

Article	Year
Probing ligand recognition in the decarboxylase antibody 21D8: implications for the catalytic mechanism. Biochemistry\| PubMed ID: 11790098	2002
Catalysis on the coastline: theozyme, molecular dynamics, and free energy perturbation analysis of antibody 21D8 catalysis of the decarboxylation of 5-nitro-3-carboxybenzisoxazole. Journal of computational chemistry\| PubMed ID: 12483679	2003
Epothilone C macrolactonization and hydrolysis are catalyzed by the isolated thioesterase domain of epothilone polyketide synthase. Journal of the American Chemical Society\| PubMed ID: 12643694	2003
Precursor-directed biosynthesis of epothilone in Escherichia coli. Journal of the American Chemical Society\| PubMed ID: 15198579	2004
Nonspecific medium effects versus specific group positioning in the antibody and albumin catalysis of the base-promoted ring-opening reactions of benzisoxazoles. Journal of the American Chemical Society\| PubMed ID: 15225061	2004
Total biosynthesis of antitumor nonribosomal peptides in Escherichia coli. Nature chemical biology\| PubMed ID: 16799553	2006
Biosynthesis of the 3,4-dihydroxybenzoate moieties of petrobactin by Bacillus anthracis. The Journal of organic chemistry\| PubMed ID: 18582113	2008
The missing link in petrobactin biosynthesis: asbF encodes a (-)-3-dehydroshikimate dehydratase. Biochemistry\| PubMed ID: 18975921	2008
Complete sequence of biosynthetic gene cluster responsible for producing triostin A and evaluation of quinomycin-type antibiotics from Streptomyces triostinicus. Biotechnology progress\| PubMed ID: 19194935	2008
Chapter 15. Plasmid-borne gene cluster assemblage and heterologous biosynthesis of nonribosomal peptides in Escherichia coli. Methods in enzymology\| PubMed ID: 19374991	2009
Escherichia coli allows efficient modular incorporation of newly isolated quinomycin biosynthetic enzyme into echinomycin biosynthetic pathway for rational design and synthesis of potent ant... Journal of the American Chemical Society\| PubMed ID: 19514719	2009
Rationally engineered total biosynthesis of a synthetic analogue of a natural quinomycin depsipeptide in Escherichia coli. Chembiochem : a European journal of chemical biology\| PubMed ID: 19588480	2009
Differences in the risk of celiac disease associated with HLA-DQ2.5 or HLA-DQ2.2 are related to sustained gluten antigen presentation. Nature immunology\| PubMed ID: 19718029	2009
Siderophore-mediated iron acquisition in Bacillus anthracis and related strains. Microbiology (Reading, England)\| PubMed ID: 20466767	2010
Enzymatic epoxide-opening cascades catalyzed by a pair of epoxide hydrolases in the ionophore polyether biosynthesis. Organic letters\| PubMed ID: 21375229	2011
Structural and functional studies of trans-encoded HLA-DQ2.3 (DQA103:01/DQB102:01) protein molecule. The Journal of biological chemistry\| PubMed ID: 22362761	2012
Enzymatic catalysis of anti-Baldwin ring closure in polyether biosynthesis. Nature\| PubMed ID: 22388816	2012
Establishing a new methodology for genome mining and biosynthesis of polyketides and peptides through yeast molecular genetics. Chembiochem : a European journal of chemical biology\| PubMed ID: 22447505	2012
Overexpressing transcriptional regulator in Aspergillus oryzae activates a silent biosynthetic pathway to produce a novel polyketide. Chembiochem : a European journal of chemical biology\| PubMed ID: 22447538	2012
Overexpressing transcriptional regulator in Chaetomium globosum activates a silent biosynthetic pathway: evaluation of shanorellin biosynthesis. The Journal of antibiotics\| PubMed ID: 22569160	2012
Combinatorial generation of complexity by redox enzymes in the chaetoglobosin A biosynthesis. Journal of the American Chemical Society\| PubMed ID: 23611317	2013
Yeast-based genome mining, production and mechanistic studies of the biosynthesis of fungal polyketide and peptide natural products. Natural product reports\| PubMed ID: 23824111	2013
Echinomycin biosynthesis. Current opinion in chemical biology\| PubMed ID: 23856054	2013
Targeted disruption of transcriptional regulators in Chaetomium globosum activates biosynthetic pathways and reveals transcriptional regulator-like behavior of aureonitol. Journal of the American Chemical Society\| PubMed ID: 23941144	2013
Engineering the polyproline II propensity of a class II major histocompatibility complex ligand peptide. ACS chemical biology\| PubMed ID: 24001370	2013
Distinct mechanisms for spiro-carbon formation reveal biosynthetic pathway crosstalk. Nature chemical biology\| PubMed ID: 24121553	2013
Conversion of a disulfide bond into a thioacetal group during echinomycin biosynthesis. Angewandte Chemie (International ed. in English)\| PubMed ID: 24302672	2014
Cytochrome P450 as dimerization catalyst in diketopiperazine alkaloid biosynthesis. Chembiochem : a European journal of chemical biology\| PubMed ID: 24677498	2014
Biophysical properties of intrinsically disordered p130Cas substrate domain--implication in mechanosensing. PLoS computational biology\| PubMed ID: 24722239	2014
Elucidation of pseurotin biosynthetic pathway points to trans-acting C-methyltransferase: generation of chemical diversity. Angewandte Chemie (International ed. in English)\| PubMed ID: 24939566	2014
Non-heme dioxygenase catalyzes atypical oxidations of 6,7-bicyclic systems to form the 6,6-quinolone core of viridicatin-type fungal alkaloids. Angewandte Chemie (International ed. in English)\| PubMed ID: 25251934	2014
Epoxide hydrolase-lasalocid a structure provides mechanistic insight into polyether natural product biosynthesis. Journal of the American Chemical Society\| PubMed ID: 25535803	2015
Involvement of Lipocalin-like CghA in Decalin-Forming Stereoselective Intramolecular [4+2] Cycloaddition. Chembiochem : a European journal of chemical biology\| PubMed ID: 26360642	2015
Elucidation of Pyranonigrin Biosynthetic Pathway Reveals a Mode of Tetramic Acid, Fused γ-Pyrone, and exo-Methylene Formation. Organic letters\| PubMed ID: 26414728	2015
Oxidative trans to cis Isomerization of Olefins in Polyketide Biosynthesis. Angewandte Chemie (International ed. in English)\| PubMed ID: 27072782	2016