Leslie Tung

Department of Biomedical Engineering, Johns Hopkins University

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 55	2017

Other Publications

Article	Year
Effects of uniform electric fields on intracellular calcium transients in single cardiac cells. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 11748049	2002
Spatial heterogeneity of transmembrane potential responses of single guinea-pig cardiac cells during electric field stimulation. The Journal of physiology\| PubMed ID: 12122146	2002
Decomposition of field-induced transmembrane potential responses of single cardiac cells. IEEE transactions on bio-medical engineering\| PubMed ID: 12214875	2002
A novel algorithm for cardiac biosignal filtering based on filtered residue method. IEEE transactions on bio-medical engineering\| PubMed ID: 12450361	2002
Functional reentry in cultured monolayers of neonatal rat cardiac cells. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 12623789	2003
Stretch-induced excitation and action potential changes of single cardiac cells. Progress in biophysics and molecular biology\| PubMed ID: 12732271	2003
Fluorescence imaging of electrical activity in cardiac cells using an all-solid-state system. IEEE transactions on bio-medical engineering\| PubMed ID: 14765706	2004
Ionic currents involved in shock-induced nonlinear changes in transmembrane potential responses of single cardiac cells. Pflugers Archiv : European journal of physiology\| PubMed ID: 15480751	2004
Multiarm spirals in a two-dimensional cardiac substrate. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15492227	2004
Paradoxical loss of excitation with high intensity pulses during electric field stimulation of single cardiac cells. Biophysical journal\| PubMed ID: 15665123	2005
Mechanoelectrical excitation by fluid jets in monolayers of cultured cardiac myocytes. Journal of applied physiology (Bethesda, Md. : 1985)\| PubMed ID: 15731396	2005
Antiarrhythmic engineering of skeletal myoblasts for cardiac transplantation. Circulation research\| PubMed ID: 15976318	2005
Acceleration of functional reentry by rapid pacing in anisotropic cardiac monolayers: formation of multi-wave functional reentries. Cardiovascular research\| PubMed ID: 16274682	2006
Structure-related initiation of reentry by rapid pacing in monolayers of cardiac cells. Circulation research\| PubMed ID: 16469953	2006
Proarrhythmic potential of mesenchymal stem cell transplantation revealed in an in vitro coculture model. Circulation\| PubMed ID: 16606790	2006
Inter-pulse interval between rectangular voltage pulses affects electroporation threshold of artificial lipid bilayers. IEEE transactions on nanobioscience\| PubMed ID: 16696301	2002
Electrical pacing counteracts intrinsic shortening of action potential duration of neonatal rat ventricular cells in culture. Journal of molecular and cellular cardiology\| PubMed ID: 16950369	2006
Optical imaging of arrhythmias in tissue culture. Journal of electrocardiology\| PubMed ID: 17015066	2006
Spiral wave attachment to millimeter-sized obstacles. Circulation\| PubMed ID: 17088465	2006
Gene transfer of connexin43 mutants attenuates coupling in cardiomyocytes: novel basis for modulation of cardiac conduction by gene therapy. Circulation research\| PubMed ID: 17495226	2007
Lentiviral vector-mediated expression of GFP or Kir2.1 alters the electrophysiology of neonatal rat ventricular myocytes without inducing cytotoxicity. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 17675572	2007
Novel anisotropic engineered cardiac tissues: studies of electrical propagation. Biochemical and biophysical research communications\| PubMed ID: 17689494	2007
Electric field perturbations of spiral waves attached to millimeter-size obstacles. Biophysical journal\| PubMed ID: 17921205	2008
Region [corrected] of slowed conduction acts as core for spiral wave reentry in cardiac cell monolayers. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 17965287	2008
Imaging fibrillation/defibrillation in a dish. Journal of electrocardiology\| PubMed ID: 17993331	2007
Cell cultures as models of cardiac mechanoelectric feedback. Progress in biophysics and molecular biology\| PubMed ID: 18384846	2008
Representation of collective electrical behavior of cardiac cell sheets. Biophysical journal\| PubMed ID: 18469085	2008
Myofibrillar architecture in engineered cardiac myocytes. Circulation research\| PubMed ID: 18635822	2008
IK1 heterogeneity affects genesis and stability of spiral waves in cardiac myocyte monolayers. Circulation research\| PubMed ID: 19122180	2009
Spiral waves and reentry dynamics in an in vitro model of the healed infarct border zone. Circulation research\| PubMed ID: 19815825	2009
Nanoscale cues regulate the structure and function of macroscopic cardiac tissue constructs. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 20018748	2010
Vulnerable windows define susceptibility to alternans and spatial discordance. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 20363894	2010
In vitro electrophysiological mapping of stem cells. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 20680822	2010
A universal system for highly efficient cardiac differentiation of human induced pluripotent stem cells that eliminates interline variability. PloS one\| PubMed ID: 21494607	2011
Expanding on forty years of reflection. The Journal of physiology\| PubMed ID: 21532028	2011
Mechanical coupling between myofibroblasts and cardiomyocytes slows electric conduction in fibrotic cell monolayers. Circulation\| PubMed ID: 21537003	2011
Reversible cardiac conduction block and defibrillation with high-frequency electric field. Science translational medicine\| PubMed ID: 21957174	2011
Engraftment of human embryonic stem cell derived cardiomyocytes improves conduction in an arrhythmogenic in vitro model. Journal of molecular and cellular cardiology\| PubMed ID: 22713758	2012
Dynamics of early afterdepolarization-mediated triggered activity in cardiac monolayers. Biophysical journal\| PubMed ID: 22735520	2012
Oscillation in cycle length induces transient discordant and steady-state concordant alternans in the heart. PloS one\| PubMed ID: 22792346	2012
Electrophysiological and contractile function of cardiomyocytes derived from human embryonic stem cells. Progress in biophysics and molecular biology\| PubMed ID: 22958937	2012
Cardiomyocytes derived from human induced pluripotent stem cells as models for normal and diseased cardiac electrophysiology and contractility. Progress in biophysics and molecular biology\| PubMed ID: 22971665	2012
Defibrillation Success with High Frequency Electric Fields is Related to Degree and Location of Conduction Block. Heart rhythm : the official journal of the Heart Rhythm Society\| PubMed ID: 23354078	2013
Structural and functional plasticity in long-term cultures of adult ventricular myocytes. Journal of molecular and cellular cardiology\| PubMed ID: 24076394	2013
Acute slowing of cardiac conduction in response to myofibroblast coupling to cardiomyocytes through N-cadherin. Journal of molecular and cellular cardiology\| PubMed ID: 24412534	2014
A metamorphosis distance for embryonic cardiac action potential interpolation and classification. Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention\| PubMed ID: 24505700	2013
A mutation causing Brugada syndrome identifies a mechanism for altered autonomic and oxidant regulation of cardiac sodium currents. Circulation. Cardiovascular genetics\| PubMed ID: 24795344	2014
Optical mapping of optogenetically shaped cardiac action potentials. Scientific reports\| PubMed ID: 25135113	2014
Automated grouping of action potentials of human embryonic stem cell-derived cardiomyocytes. IEEE transactions on bio-medical engineering\| PubMed ID: 25148658	2014
Physical developmental cues for the maturation of human pluripotent stem cell-derived cardiomyocytes. Stem cell research & therapy\| PubMed ID: 25688759	2014
Engineered heart slices for electrophysiological and contractile studies. Biomaterials\| PubMed ID: 25934457	2015
Variability of Action Potentials Within and Among Cardiac Cell Clusters Derived from Human Embryonic Stem Cells. Scientific reports\| PubMed ID: 26729331	2016
Tetanizing prepulse: A novel strategy to mitigate implantable cardioverter-defibrillator shock-related pain. Heart rhythm\| PubMed ID: 26767423	2016
Precisely parameterized experimental and computational models of tissue organization. Integrative biology : quantitative biosciences from nano to macro\| PubMed ID: 26822672	2016
Functional Coupling with Cardiac Muscle Promotes Maturation of hPSC-Derived Sympathetic Neurons. Cell stem cell\| PubMed ID: 27320040	2016
Adipose-derived perivascular mesenchymal stromal/stem cells promote functional vascular tissue engineering for cardiac regenerative purposes. Journal of tissue engineering and regenerative medicine\| PubMed ID: 28103423	2017
Effects of Strong Electrical Shock on Cardiac Muscle Tissuea. Annals of the New York Academy of Sciences\| PubMed ID: 28621858	1994