Jeffrey M. Peters

Department of Veterinary and Biomedical Sciences, The Pennsylvania State University

Affiliated withThe Pennsylvania State University

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 15	2017

Other Publications

Article	Year
Hepatic regeneration in peroxisome proliferator-activated receptor alpha-null mice after partial hepatectomy. Hepatology research : the official journal of the Japan Society of Hepatology\| PubMed ID: 11804834	2002
Induction of CYP3A expression by dehydroepiandrosterone: involvement of the pregnane X receptor. Drug metabolism and disposition: the biological fate of chemicals\| PubMed ID: 11950789	2002
Targeted disruption of peroxisomal proliferator-activated receptor beta (delta) results in distinct gender differences in mouse brain phospholipid and esterified FA levels. Lipids\| PubMed ID: 12056592	2002
Effects of conjugated linoleic acid (CLA) on immune responses, body composition and stearoyl-CoA desaturase. Canadian journal of applied physiology = Revue canadienne de physiologie appliquee\| PubMed ID: 12501000	2002
Bezafibrate is a dual ligand for PPARalpha and PPARbeta: studies using null mice. Biochimica et biophysica acta\| PubMed ID: 12782154	2003
Comprehensive gene expression analysis of peroxisome proliferator-treated immortalized hepatocytes: identification of peroxisome proliferator-activated receptor alpha-dependent growth regula... Cancer research\| PubMed ID: 14522898	2003
PPARalpha agonist-induced rodent tumors: modes of action and human relevance. Critical reviews in toxicology\| PubMed ID: 14727734	2003
Expression of base excision DNA repair genes is a sensitive biomarker for in vivo detection of chemical-induced chronic oxidative stress: identification of the molecular source of radicals r... Cancer research\| PubMed ID: 14871837	2004
Peroxisome proliferator-activated receptor beta/delta regulates very low density lipoprotein production and catabolism in mice on a Western diet. The Journal of biological chemistry\| PubMed ID: 15001574	2004
Peroxisome proliferator-activated receptor beta (delta)-dependent regulation of ubiquitin C expression contributes to attenuation of skin carcinogenesis. The Journal of biological chemistry\| PubMed ID: 15033975	2004
Peroxisome proliferator-activated receptor-delta attenuates colon carcinogenesis. Nature medicine\| PubMed ID: 15048110	2004
PPARgamma influences susceptibility to DMBA-induced mammary, ovarian and skin carcinogenesis. Carcinogenesis\| PubMed ID: 15073042	2004
Reduced adiposity and liver steatosis by stearoyl-CoA desaturase deficiency are independent of peroxisome proliferator-activated receptor-alpha. The Journal of biological chemistry\| PubMed ID: 15180999	2004
PPARbeta/delta potentiates PPARgamma-stimulated adipocyte differentiation. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 15247146	2004
Activation of mouse and human peroxisome proliferator-activated receptors (PPARs) by phthalate monoesters. Toxicological sciences : an official journal of the Society of Toxicology\| PubMed ID: 15310864	2004
The United States-Japan workshop on: The role of nuclear receptors in carcinogenesis. Molecular carcinogenesis\| PubMed ID: 15378646	2004
Peroxisome proliferator-activated receptor alpha protects against alcohol-induced liver damage. Hepatology (Baltimore, Md.)\| PubMed ID: 15382117	2004
Role of peroxisome proliferator-activated receptor-alpha (PPARalpha) in bezafibrate-induced hepatocarcinogenesis and cholestasis. Carcinogenesis\| PubMed ID: 15447978	2005
PPARdelta status and Apc-mediated tumourigenesis in the mouse intestine. Oncogene\| PubMed ID: 15480419	2004
Regulation of human apoA-I by gemfibrozil and fenofibrate through selective peroxisome proliferator-activated receptor alpha modulation. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 15618549	2005
Peroxisome proliferator-activated receptor-beta/delta inhibits epidermal cell proliferation by down-regulation of kinase activity. The Journal of biological chemistry\| PubMed ID: 15632134	2005
Differences in cell proliferation in rodent and human hepatic derived cell lines exposed to ciprofibrate. Cancer letters\| PubMed ID: 15863271	2005
Peroxisome proliferator-activated receptor-alpha and liver cancer: where do we stand? Journal of molecular medicine (Berlin, Germany)\| PubMed ID: 15976920	2005
Protective effects of a peroxisome proliferator-activated receptor-beta/delta agonist in experimental autoimmune encephalomyelitis. Journal of neuroimmunology\| PubMed ID: 16098614	2005
The role of peroxisome proliferator-activated receptor-beta/delta in epithelial cell growth and differentiation. Cellular signalling\| PubMed ID: 16109478	2006
Evidence that ligand binding is a key determinant of Ah receptor-mediated transcriptional activity. Archives of biochemistry and biophysics\| PubMed ID: 16137638	2005
The aryl hydrocarbon receptor directly regulates expression of the potent mitogen epiregulin. Toxicological sciences : an official journal of the Society of Toxicology\| PubMed ID: 16192470	2006
The toxicology of ligands for peroxisome proliferator-activated receptors (PPAR). Toxicological sciences : an official journal of the Society of Toxicology\| PubMed ID: 16322072	2006
Alterations in skin and stratified epithelia by constitutively activated PPARalpha. The Journal of investigative dermatology\| PubMed ID: 16374467	2006
Inhibition of chemically induced skin carcinogenesis by sulindac is independent of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta). Carcinogenesis\| PubMed ID: 16418176	2006
PPARdelta regulates glucose metabolism and insulin sensitivity. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16492734	2006
Ligand activation of peroxisome proliferator-activated receptor beta inhibits colon carcinogenesis. Cancer research\| PubMed ID: 16618765	2006
PPARdelta status and mismatch repair mediated neoplasia in the mouse intestine. BMC cancer\| PubMed ID: 16672050	2006
Regulation of hepatic fatty acid elongase and desaturase expression in diabetes and obesity. Journal of lipid research\| PubMed ID: 16790840	2006
Modes of action and species-specific effects of di-(2-ethylhexyl)phthalate in the liver. Critical reviews in toxicology\| PubMed ID: 16954067	2006
Sustained formation of alpha-(4-pyridyl-1-oxide)-N-tert-butylnitrone radical adducts in mouse liver by peroxisome proliferators is dependent upon peroxisome proliferator-activated receptor-a... Free radical biology & medicine\| PubMed ID: 17210446	2007
Ligand activation of peroxisome proliferator-activated receptor-beta/delta(PPARbeta/delta) inhibits cell growth of human N/TERT-1 keratinocytes. Cellular signalling\| PubMed ID: 17254750	2007
PPARalpha and effects of TCE. Environmental health perspectives\| PubMed ID: 17366801	2007
The oxidative stress mediator 4-hydroxynonenal is an intracellular agonist of the nuclear receptor peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta). Free radical biology & medicine\| PubMed ID: 17382197	2007
PPARbeta/delta protects against experimental colitis through a ligand-independent mechanism. Digestive diseases and sciences\| PubMed ID: 17404849	2007
Deregulation of tumor angiogenesis and blockade of tumor growth in PPARbeta-deficient mice. The EMBO journal\| PubMed ID: 17641685	2007
Transcriptional network governing the angiogenic switch in human pancreatic cancer. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17652168	2007
Growth of transgenic RAF-induced lung adenomas is increased in mice with a disrupted PPARbeta/delta gene. International journal of oncology\| PubMed ID: 17671688	2007
Peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) ligands do not potentiate growth of human cancer cell lines. Carcinogenesis\| PubMed ID: 17693664	2007
COX-2 suppresses tissue factor expression via endocannabinoid-directed PPARdelta activation. The Journal of experimental medicine\| PubMed ID: 17724132	2007
Ligand activation of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) and inhibition of cyclooxygenase 2 (COX2) attenuate colon carcinogenesis through independent signa... Carcinogenesis\| PubMed ID: 17893232	2008
Induction of nuclear translocation of constitutive androstane receptor by peroxisome proliferator-activated receptor alpha synthetic ligands in mouse liver. The Journal of biological chemistry\| PubMed ID: 17962186	2007
Peroxisome proliferator-activated receptor-beta/delta protects against chemically induced liver toxicity in mice. Hepatology (Baltimore, Md.)\| PubMed ID: 18038451	2008
Peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) ligands inhibit growth of UACC903 and MCF7 human cancer cell lines. Toxicology\| PubMed ID: 18054822	2008
Quantitative expression patterns of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) protein in mice. Biochemical and biophysical research communications\| PubMed ID: 18442472	2008
A Role for PPARbeta/delta in Tumor Stroma and Tumorigenesis. PPAR research\| PubMed ID: 18497874	2008
Role of peroxisome-proliferator-activated receptor beta/delta (PPARbeta/delta) in gastrointestinal tract function and disease. Clinical science (London, England : 1979)\| PubMed ID: 18616431	2008
Ligand activation of peroxisome proliferator-activated receptor beta/delta (PPARbeta/delta) attenuates carbon tetrachloride hepatotoxicity by downregulating proinflammatory gene expression. Toxicological sciences : an official journal of the Society of Toxicology\| PubMed ID: 18622026	2008
Ligand activation of peroxisome proliferator-activated receptor-beta/delta inhibits cell proliferation in human HaCaT keratinocytes. Molecular pharmacology\| PubMed ID: 18687807	2008
Peroxisome proliferator-activated receptor-delta agonist enhances vasculogenesis by regulating endothelial progenitor cells through genomic and nongenomic activations of the phosphatidylinos... Circulation\| PubMed ID: 18711014	2008
Nrf2- and PPAR alpha-mediated regulation of hepatic Mrp transporters after exposure to perfluorooctanoic acid and perfluorodecanoic acid. Toxicological sciences : an official journal of the Society of Toxicology\| PubMed ID: 18757529	2008
Ligand activation of peroxisome proliferator-activated receptor beta/delta (PPAR beta/delta) inhibits chemically induced skin tumorigenesis. Carcinogenesis\| PubMed ID: 18799709	2008
Effect of ligand activation of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) in human lung cancer cell lines. Toxicology\| PubMed ID: 18950674	2008
PPARdelta is pro-tumorigenic in a mouse model of COX-2-induced mammary cancer. Prostaglandins & other lipid mediators\| PubMed ID: 19101649	2009
Regulation of peroxisome proliferator-activated receptor-alpha by MDM2. Toxicological sciences : an official journal of the Society of Toxicology\| PubMed ID: 19103650	2009
Regulation of peroxisome proliferator-activated receptors by e6-associated protein. PPAR research\| PubMed ID: 19107217	2008
Differential hepatic effects of perfluorobutyrate mediated by mouse and human PPAR-alpha. Toxicological sciences : an official journal of the Society of Toxicology\| PubMed ID: 19359353	2009
Regulation of peroxisome proliferator-activated receptor-beta/delta by the APC/beta-CATENIN pathway and nonsteroidal antiinflammatory drugs. Molecular carcinogenesis\| PubMed ID: 19415698	2009
Sorting out the functional role(s) of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) in cell proliferation and cancer. Biochimica et biophysica acta\| PubMed ID: 19505534	2009
Ligand activation of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) inhibits cell growth in a mouse mammary gland cancer cell line. Cancer letters\| PubMed ID: 19660859	2010
Ligand activation of peroxisome proliferator-activated receptor-beta/delta and inhibition of cyclooxygenase-2 enhances inhibition of skin tumorigenesis. Toxicological sciences : an official journal of the Society of Toxicology\| PubMed ID: 19748995	2010
Regulation of oligodendrocyte progenitor cell maturation by PPARδ: effects on bone morphogenetic proteins. ASN neuro\| PubMed ID: 20001953	2010
A natural propenoic acid derivative activates peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta). Life sciences\| PubMed ID: 20153754	2010
Cellular and pharmacological selectivity of the peroxisome proliferator-activated receptor-beta/delta antagonist GSK3787. Molecular pharmacology\| PubMed ID: 20516370	2010
Synthesis of isosteric selenium analog of the PPARbeta/delta agonist GW501516 and comparison of biological activity. Bioorganic & medicinal chemistry letters\| PubMed ID: 20542425	2010
Effect of prenatal peroxisome proliferator-activated receptor alpha (PPARalpha) agonism on postnatal development. Toxicology\| PubMed ID: 20637823	2010
Xenobiotic metabolism, disposition, and regulation by receptors: from biochemical phenomenon to predictors of major toxicities. Toxicological sciences : an official journal of the Society of Toxicology\| PubMed ID: 21059794	2011
Chemoprevention of chemically induced skin tumorigenesis by ligand activation of peroxisome proliferator-activated receptor-beta/delta and inhibition of cyclooxygenase 2. Molecular cancer therapeutics\| PubMed ID: 21159610	2010
PPARβ/δ activation induces enteroendocrine L cell GLP-1 production. Gastroenterology\| PubMed ID: 21300064	2011
Functional characterization of peroxisome proliferator-activated receptor-β/δ expression in colon cancer. Molecular carcinogenesis\| PubMed ID: 21400612	2011
Stable over-expression of PPARβ/δ and PPARγ to examine receptor signaling in human HaCaT keratinocytes. Cellular signalling\| PubMed ID: 21843636	2011
PPAR action in insulin resistance unraveled by metabolomics: potential clinical implications. Genome medicine\| PubMed ID: 21861850	2011
Why toxic equivalency factors are not suitable for perfluoroalkyl chemicals. Chemical research in toxicology\| PubMed ID: 21913657	2011
Immunomodulatory action of dietary fish oil and targeted deletion of intestinal epithelial cell PPARδ in inflammation-induced colon carcinogenesis. American journal of physiology. Gastrointestinal and liver physiology\| PubMed ID: 21940900	2012
NTP-CERHR expert panel report on the developmental toxicity of soy infant formula. Birth defects research. Part B, Developmental and reproductive toxicology\| PubMed ID: 21948615	2011
Dissecting the role of peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) in colon, breast, and lung carcinogenesis. Cancer metastasis reviews\| PubMed ID: 22037942	2011
The role of peroxisome proliferator-activated receptors in carcinogenesis and chemoprevention. Nature reviews. Cancer\| PubMed ID: 22318237	2012
Peroxisome proliferator-activated receptor β/δ cross talks with E2F and attenuates mitosis in HRAS-expressing cells. Molecular and cellular biology\| PubMed ID: 22473992	2012
Modulation of gastrointestinal inflammation and colorectal tumorigenesis by peroxisome proliferator-activated receptor-β/δ (PPARβ/δ). Drug discovery today. Disease mechanisms\| PubMed ID: 22611424	2011
A species difference in the peroxisome proliferator-activated receptor α-dependent response to the developmental effects of perfluorooctanoic acid. Toxicological sciences : an official journal of the Society of Toxicology\| PubMed ID: 23143925	2013
Analysis of the peroxisome proliferator-activated receptor-Î²/Î´ (PPARÎ²/Î´) cistrome reveals novel co-regulatory role of ATF4. BMC genomics\| PubMed ID: 23176727	2012
Metabolomics: an essential tool to understand the function of peroxisome proliferator-activated receptor alpha. Toxicologic pathology\| PubMed ID: 23197196	2013
Cholestasis induces reversible accumulation of periplakin in mouse liver. BMC gastroenterology\| PubMed ID: 23849208	2013
PPARβ/δ modulates ethanol-induced hepatic effects by decreasing pyridoxal kinase activity. Toxicology\| PubMed ID: 23851158	2013
Mode of action framework analysis for receptor-mediated toxicity: The peroxisome proliferator-activated receptor alpha (PPARα) as a case study. Critical reviews in toxicology\| PubMed ID: 24180432	2014
Aryl hydrocarbon receptor antagonism attenuates growth factor expression, proliferation, and migration in fibroblast-like synoviocytes from patients with rheumatoid arthritis. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 24309559	2014
Targeting estrogen receptor-β for the prevention of nonmelanoma skin cancer. Cancer prevention research (Philadelphia, Pa.)\| PubMed ID: 24464730	2014
Activation of peroxisome proliferator-activated receptor-β/δ (PPAR-β/δ) inhibits human breast cancer cell line tumorigenicity. Molecular cancer therapeutics\| PubMed ID: 24464939	2014
Modulation of aryl hydrocarbon receptor (AHR)-dependent signaling by peroxisome proliferator-activated receptor β/δ (PPARβ/δ) in keratinocytes. Carcinogenesis\| PubMed ID: 24639079	2014
The nuclear receptor peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) promotes oncogene-induced cellular senescence through repression of endoplasmic reticulum stress. The Journal of biological chemistry\| PubMed ID: 24898257	2014
Comparative in vivo and in vitro analysis of possible estrogenic effects of perfluorooctanoic acid. Toxicology\| PubMed ID: 25456267	2014
M-CSF from Cancer Cells Induces Fatty Acid Synthase and PPARβ/δ Activation in Tumor Myeloid Cells, Leading to Tumor Progression. Cell reports\| PubMed ID: 25753425	2015
Targeting Peroxisome Proliferator-Activated Receptor-β/δ (PPARβ/δ) for Cancer Chemoprevention. Current pharmacology reports\| PubMed ID: 26000234	2015
Peroxisome Proliferator-activated Receptor-D (PPARD) Coordinates Mouse Spermatogenesis by Modulating Extracellular Signal-regulated Kinase (ERK)-dependent Signaling. The Journal of biological chemistry\| PubMed ID: 26242735	2015
Inhibition of testicular embryonal carcinoma cell tumorigenicity by peroxisome proliferator-activated receptor-β/δ- and retinoic acid receptor-dependent mechanisms. Oncotarget\| PubMed ID: 26431381	2015
Establishing the Role of PPARβ/δ in Carcinogenesis. Trends in endocrinology and metabolism: TEM\| PubMed ID: 26490384	2015
The Ron Receptor Tyrosine Kinase Regulates Macrophage Heterogeneity and Plays a Protective Role in Diet-Induced Obesity, Atherosclerosis, and Hepatosteatosis. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 27233965	2016
Editor's Highlight: Perfluorooctane Sulfonate-Choline Ion Pair Formation: A Potential Mechanism Modulating Hepatic Steatosis and Oxidative Stress in Mice. Toxicological sciences : an official journal of the Society of Toxicology\| PubMed ID: 27413108	2016
Ligand activation of peroxisome proliferator-activated receptor-β/δ suppresses liver tumorigenesis in hepatitis B transgenic mice. Toxicology\| PubMed ID: 27427494	2016
PPARβ/δ selectively regulates phenotypic features of age-related macular degeneration. Aging\| PubMed ID: 27622388	2016
Regulation of Cytochrome P450 2B10 (CYP2B10) Expression in Liver by Peroxisome Proliferator-activated Receptor-β/δ Modulation of SP1 Promoter Occupancy. The Journal of biological chemistry\| PubMed ID: 27765815	2016
Omics Approaches To Probe Microbiota and Drug Metabolism Interactions. Chemical research in toxicology\| PubMed ID: 27782392	2016
Peroxisome proliferator-activated receptor-β/δ modulates mast cell phenotype. Immunology\| PubMed ID: 27935639	2017
Peroxisome proliferator-activated receptor-β/δ inhibits human neuroblastoma cell tumorigenesis by inducing p53- and SOX2-mediated cell differentiation. Molecular carcinogenesis\| PubMed ID: 27996177	2016