Paul H. Patterson

Department of Biology, California Institute of Technology

Affiliated withCalifornia Institute of Technology

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 395	2011

Other Publications

Article	Year
Effects of intracellular expression of anti-huntingtin antibodies of various specificities on mutant huntingtin aggregation and toxicity. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 11792860	2002
Maternal infection: window on neuroimmune interactions in fetal brain development and mental illness. Current opinion in neurobiology\| PubMed ID: 11861174	2002
Prenatal viral infection leads to pyramidal cell atrophy and macrocephaly in adulthood: implications for genesis of autism and schizophrenia. Cellular and molecular neurobiology\| PubMed ID: 12064515	2002
Denervated Schwann cells attract macrophages by secretion of leukemia inhibitory factor (LIF) and monocyte chemoattractant protein-1 in a process regulated by interleukin-6 and LIF. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 12151548	2002
Maternal influenza infection causes marked behavioral and pharmacological changes in the offspring. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 12514227	2003
Developmental cooperation of leukemia inhibitory factor and insulin-like growth factor I in mice is tissue-specific and essential for lung maturation involving the transcription factors Sp3 ... Mechanisms of development\| PubMed ID: 12591604	2003
Lymphocyte regulation of neuropeptide gene expression after neuronal injury. Journal of neuroscience research\| PubMed ID: 14515353	2003
Neonatal impact of leukemia inhibitory factor on neurobehavioral development in rats. Neuroscience research\| PubMed ID: 15154680	2004
Antibodies against huntingtin: production and screening of monoclonals and single-chain recombinant forms. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 15201451	2004
Potent pro-inflammatory actions of leukemia inhibitory factor in the spinal cord of the adult mouse. Experimental neurology\| PubMed ID: 15246839	2004
Activation of the IkappaB kinase complex and nuclear factor-kappaB contributes to mutant huntingtin neurotoxicity. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 15371500	2004
Targeted overexpression of leukemia inhibitory factor to preserve myocardium in a rat model of postinfarction heart failure. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 15573071	2004
Endothelin receptor B inhibition triggers apoptosis and enhances angiogenesis in melanomas. Cancer research\| PubMed ID: 15604257	2004
Maternal influenza infection is likely to alter fetal brain development indirectly: the virus is not detected in the fetus. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience\| PubMed ID: 15749254	2005
Leukemia inhibitory factor promotes oligodendrocyte survival after spinal cord injury. Glia\| PubMed ID: 15779090	2005
The cell cycle-apoptosis connection revisited in the adult brain. The Journal of cell biology\| PubMed ID: 16291699	2005
Leukemia inhibitory factor is a key regulator of astrocytic, microglial and neuronal responses in a low-dose pilocarpine injury model. Brain research\| PubMed ID: 16458863	2006
Autism: neuropathology, alterations of the GABAergic system, and animal models. International review of neurobiology\| PubMed ID: 16512344	2005
Behavioral stress and tumor progression. Anticancer research\| PubMed ID: 16619523	2006
Leukemia inhibitory factor promotes neural stem cell self-renewal in the adult brain. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 17108182	2006
The neuropoietic cytokine family in development, plasticity, disease and injury. Nature reviews. Neuroscience\| PubMed ID: 17311007	2007
A chronically implantable, hybrid cannula-electrode device for assessing the effects of molecules on electrophysiological signals in freely behaving animals. Journal of neuroscience methods\| PubMed ID: 17499854	2007
Molecular basis for passive immunotherapy of Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17895381	2007
Maternal immune activation alters fetal brain development through interleukin-6. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 17913903	2007
Neuroscience. Maternal effects on schizophrenia risk. Science (New York, N.Y.)\| PubMed ID: 17962542	2007
Activation of the maternal immune system alters cerebellar development in the offspring. Brain, behavior, and immunity\| PubMed ID: 18755264	2009
Intrabodies binding the proline-rich domains of mutant huntingtin increase its turnover and reduce neurotoxicity. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 18768695	2008
Endothelin receptor B antagonists decrease glioma cell viability independently of their cognate receptor. BMC cancer\| PubMed ID: 19040731	2008
Immune involvement in schizophrenia and autism: etiology, pathology and animal models. Behavioural brain research\| PubMed ID: 19136031	2009
IKKalpha and IKKbeta regulation of DNA damage-induced cleavage of huntingtin. PloS one\| PubMed ID: 19488402	2009
Monoclonal antibodies recognize distinct conformational epitopes formed by polyglutamine in a mutant huntingtin fragment. The Journal of biological chemistry\| PubMed ID: 19491400	2009
Cytokines and CNS development. Neuron\| PubMed ID: 19840550	2009
Intrabody gene therapy ameliorates motor, cognitive, and neuropathological symptoms in multiple mouse models of Huntington's disease. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 19864571	2009
IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome. The Journal of cell biology\| PubMed ID: 20026656	2009
Maternal immune activation alters nonspatial information processing in the hippocampus of the adult offspring. Brain, behavior, and immunity\| PubMed ID: 20227486	2010
Pulsed UV light inactivation of Salmonella enteritidis on eggshells and its effects on egg quality. Journal of food protection\| PubMed ID: 20819349	2010
Antibody therapy in neurodegenerative disease. Reviews in the neurosciences\| PubMed ID: 21086760	2010
Maternal infection and schizophrenia: implications for prevention. Schizophrenia bulletin\| PubMed ID: 21134972	2011
Activation of the maternal immune system induces endocrine changes in the placenta via IL-6. Brain, behavior, and immunity\| PubMed ID: 21195166	2011
Modeling autistic features in animals. Pediatric research\| PubMed ID: 21289542	2011
Perturbation with intrabodies reveals that calpain cleavage is required for degradation of huntingtin exon 1. PloS one\| PubMed ID: 21304966	2011
Maternal infection and immune involvement in autism. Trends in molecular medicine\| PubMed ID: 21482187	2011
Gene therapy in mouse models of huntington disease. The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry\| PubMed ID: 21489966	2011
The role of IÎºB kinase complex in the neurobiology of Huntington's disease. Neurobiology of disease\| PubMed ID: 21554955	2011
Maternal infection and autism. Brain, behavior, and immunity\| PubMed ID: 22001185	2011
Deletion of densin-180 results in abnormal behaviors associated with mental illness and reduces mGluR5 and DISC1 in the postsynaptic density fraction. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 22072671	2011
Maternal immune activation yields offspring displaying mouse versions of the three core symptoms of autism. Brain, behavior, and immunity\| PubMed ID: 22310922	2012
Exogenous leukemia inhibitory factor stimulates oligodendrocyte progenitor cell proliferation and enhances hippocampal remyelination. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 22323722	2012