Lies Langouche

Clinical Division and Laboratory of Intensive Care Medicine, KU Leuven

Affiliated withKU Leuven

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 18	2017

Other Publications

Article	Year
Structure-activity relationship and signal transduction of gamma-MSH peptides in GH3 cells: further evidence for a new melanocortin receptor. Peptides\| PubMed ID: 12126734	2002
Glycemic and nonglycemic effects of insulin: how do they contribute to a better outcome of critical illness? Current opinion in critical care\| PubMed ID: 16015107	2005
Intensive insulin therapy protects the endothelium of critically ill patients. The Journal of clinical investigation\| PubMed ID: 16075063	2005
The role of insulin therapy in critically ill patients. Treatments in endocrinology\| PubMed ID: 16318401	2005
Glucose metabolism and insulin therapy. Critical care clinics\| PubMed ID: 16399023	2006
Survival benefits of intensive insulin therapy in critical illness: impact of maintaining normoglycemia versus glycemia-independent actions of insulin. Diabetes\| PubMed ID: 16567534	2006
Intensive insulin therapy in the intensive care unit: update on clinical impact and mechanisms of action. Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists\| PubMed ID: 16905512	2006
Endocrine aspects of acute and prolonged critical illness. Nature clinical practice. Endocrinology & metabolism\| PubMed ID: 16932250	2006
The dynamic neuroendocrine response to critical illness. Endocrinology and metabolism clinics of North America\| PubMed ID: 17127146	2006
Therapy insight: the effect of tight glycemic control in acute illness. Nature clinical practice. Endocrinology & metabolism\| PubMed ID: 17315035	2007
Modulating the endocrine response in sepsis: insulin and blood glucose control. Novartis Foundation symposium\| PubMed ID: 17380796	2007
The type II iodothyronine deiodinase is up-regulated in skeletal muscle during prolonged critical illness. The Journal of clinical endocrinology and metabolism\| PubMed ID: 17504898	2007
Indication and practical use of intensive insulin therapy in the critically ill. Current opinion in critical care\| PubMed ID: 17599008	2007
Tight blood glucose control with insulin in the ICU: facts and controversies. Chest\| PubMed ID: 17625087	2007
Effect of intensive insulin therapy on insulin sensitivity in the critically ill. The Journal of clinical endocrinology and metabolism\| PubMed ID: 17666481	2007
Tight blood glucose control: what is the evidence? Critical care medicine\| PubMed ID: 17713399	2007
Glycemic control modulates arginine and asymmetrical-dimethylarginine levels during critical illness by preserving dimethylarginine-dimethylaminohydrolase activity. Endocrinology\| PubMed ID: 18292189	2008
Modulation of regional nitric oxide metabolism: blood glucose control or insulin? Intensive care medicine\| PubMed ID: 18427775	2008
Effect of insulin therapy on coagulation and fibrinolysis in medical intensive care patients. Critical care medicine\| PubMed ID: 18434900	2008
Polymorphisms in innate immunity genes predispose to bacteremia and death in the medical intensive care unit. Critical care medicine\| PubMed ID: 19050632	2009
Expression of thyroid hormone transporters during critical illness. European journal of endocrinology\| PubMed ID: 19439506	2009
Adiponectin, retinol-binding protein 4, and leptin in protracted critical illness of pulmonary origin. Critical care (London, England)\| PubMed ID: 19589139	2009
Changes in the central component of the hypothalamus-pituitary-thyroid axis in a rabbit model of prolonged critical illness. Critical care (London, England)\| PubMed ID: 19747372	2009
Molecular mechanisms behind clinical benefits of intensive insulin therapy during critical illness: glucose versus insulin. Best practice & research. Clinical anaesthesiology\| PubMed ID: 20108584	2009
Alterations in adipose tissue during critical illness: An adaptive and protective response? American journal of respiratory and critical care medicine\| PubMed ID: 20442437	2010
Tight glycemic control protects the myocardium and reduces inflammation in neonatal heart surgery. The Annals of thoracic surgery\| PubMed ID: 20609741	2010
Molecular analysis of sepsis-induced changes in the liver: microarray study in a porcine model of acute fecal peritonitis with fluid resuscitation. Shock (Augusta, Ga.)\| PubMed ID: 20610940	2010
Critical illness evokes elevated circulating bile acids related to altered hepatic transporter and nuclear receptor expression. Hepatology (Baltimore, Md.)\| PubMed ID: 21800341	2011
Critical illness induces alternative activation of M2 macrophages in adipose tissue. Critical care (London, England)\| PubMed ID: 22018099	2011
Contribution of nutritional deficit to the pathogenesis of the nonthyroidal illness syndrome in critical illness: a rabbit model study. Endocrinology\| PubMed ID: 22166982	2012
Effect of tight glucose control with insulin on the thyroid axis of critically ill children and its relation with outcome. The Journal of clinical endocrinology and metabolism\| PubMed ID: 22872689	2012
Endocrine, metabolic, and morphologic alterations of adipose tissue during critical illness. Critical care medicine\| PubMed ID: 23135416	2013
Impact of early nutrient restriction during critical illness on the nonthyroidal illness syndrome and its relation with outcome: a randomized, controlled clinical study. The Journal of clinical endocrinology and metabolism\| PubMed ID: 23348400	2013
Reduced cortisol metabolism during critical illness. The New England journal of medicine\| PubMed ID: 23506003	2013
Impact of early parenteral nutrition on muscle and adipose tissue compartments during critical illness. Critical care medicine\| PubMed ID: 23860247	2013
Critical illness induces nutrient-independent adipogenesis and accumulation of alternatively activated tissue macrophages. Critical care (London, England)\| PubMed ID: 24020372	2013
Impact of parenteral nutrition versus fasting on hepatic bile acid production and transport in a rabbit model of prolonged critical illness. Shock (Augusta, Ga.)\| PubMed ID: 24089008	2014
Withholding parenteral nutrition during critical illness increases plasma bilirubin but lowers the incidence of biliary sludge. Hepatology (Baltimore, Md.)\| PubMed ID: 24213952	2014
The authors reply. Critical care medicine\| PubMed ID: 24736366	2014
Impact of duration of critical illness on the adrenal glands of human intensive care patients. The Journal of clinical endocrinology and metabolism\| PubMed ID: 25062464	2014
Hypothalamic-pituitary hormones during critical illness: a dynamic neuroendocrine response. Handbook of clinical neurology\| PubMed ID: 25248583	2014
Effect of Early Parenteral Nutrition on the HPA Axis and on Treatment With Corticosteroids in Intensive Care Patients. The Journal of clinical endocrinology and metabolism\| PubMed ID: 25942482	2015
Liver X receptor activation enhances CVB3 viral replication during myocarditis by stimulating lipogenesis. Cardiovascular research\| PubMed ID: 25998987	2015
Neuropathological Correlates of Hyperglycemia During Prolonged Polymicrobial Sepsis in Mice. Shock (Augusta, Ga.)\| PubMed ID: 26009823	2015
Thyroid function in critically ill patients. The lancet. Diabetes & endocrinology\| PubMed ID: 26071885	2015
Cholestatic liver (dys)function during sepsis and other critical illnesses. Intensive care medicine\| PubMed ID: 26392257	2016
Drug-induced HPA axis alterations during acute critical illness: a multivariable association study. Clinical endocrinology\| PubMed ID: 27422812	2017
Circulating 3-T1AM and 3,5-T2 in Critically Ill Patients: A Cross-Sectional Observational Study. Thyroid : official journal of the American Thyroid Association\| PubMed ID: 27676423	2016
Premorbid obesity, but not nutrition, prevents critical illness-induced muscle wasting and weakness. Journal of cachexia, sarcopenia and muscle\| PubMed ID: 27897405	2017
Stimulation of Intracellular Free Calcium in GH3 Cells byγ 3-Melanocyte-Stimulating Hormone. Involvement of a Novel Melanocortin Receptor? Endocrinology\| PubMed ID: 28201334	2001
Proliferation and differentiation of adipose tissue in prolonged lean and obese critically ill patients. Intensive care medicine experimental\| PubMed ID: 28303483	2017